PL3331998T3 - Wytwarzanie przez fermentację l-metioniny zależne od tiokarboksylanu białka - Google Patents

Wytwarzanie przez fermentację l-metioniny zależne od tiokarboksylanu białka

Info

Publication number
PL3331998T3
PL3331998T3 PL15798180T PL15798180T PL3331998T3 PL 3331998 T3 PL3331998 T3 PL 3331998T3 PL 15798180 T PL15798180 T PL 15798180T PL 15798180 T PL15798180 T PL 15798180T PL 3331998 T3 PL3331998 T3 PL 3331998T3
Authority
PL
Poland
Prior art keywords
thiocarboxylate
fermentation
protein
dependent
methionine production
Prior art date
Application number
PL15798180T
Other languages
English (en)
Inventor
Philippe Soucaille
Perrine Vasseur
Original Assignee
Evonik Operations Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Operations Gmbh filed Critical Evonik Operations Gmbh
Publication of PL3331998T3 publication Critical patent/PL3331998T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01031—Homoserine O-acetyltransferase (2.3.1.31)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y205/00—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5)
    • C12Y205/01—Transferases transferring alkyl or aryl groups, other than methyl groups (2.5) transferring alkyl or aryl groups, other than methyl groups (2.5.1)
    • C12Y205/01049—O-acetylhomoserine aminocarboxypropyltransferase (2.5.1.49)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL15798180T 2015-08-07 2015-08-07 Wytwarzanie przez fermentację l-metioniny zależne od tiokarboksylanu białka PL3331998T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/IB2015/001888 WO2017025766A1 (en) 2015-08-07 2015-08-07 Protein thiocarboxylate-dependent l-methionine production by fermentation
EP15798180.4A EP3331998B1 (en) 2015-08-07 2015-08-07 Protein thiocarboxylate-dependent l-methionine production by fermentation

Publications (1)

Publication Number Publication Date
PL3331998T3 true PL3331998T3 (pl) 2020-12-28

Family

ID=54695761

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15798180T PL3331998T3 (pl) 2015-08-07 2015-08-07 Wytwarzanie przez fermentację l-metioniny zależne od tiokarboksylanu białka

Country Status (7)

Country Link
US (1) US20180223319A1 (pl)
EP (1) EP3331998B1 (pl)
CN (1) CN108026516A (pl)
BR (1) BR112018002048A2 (pl)
MY (1) MY184139A (pl)
PL (1) PL3331998T3 (pl)
WO (1) WO2017025766A1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112018010747A8 (pt) 2015-11-27 2019-02-26 Evonik Degussa Gmbh método para a produção de l-metionina
CN109952380B (zh) * 2016-10-26 2023-07-14 味之素株式会社 用于生产目标物质的方法
WO2019238725A1 (en) * 2018-06-13 2019-12-19 Acib Gmbh - Austrian Centre Of Industrial Biotechnology Methionine analogue synthesis
KR102377500B1 (ko) * 2019-10-28 2022-03-23 씨제이제일제당 주식회사 외래 metZ 유전자에 의해 코딩되는 단백질이 도입된 L-메티오닌 생산 미생물 및 이를 이용한 L-메티오닌 생산방법
CN112501144B (zh) * 2021-02-02 2021-04-20 中国科学院天津工业生物技术研究所 高丝氨酸乙酰转移酶突变体及其在生产o-乙酰高丝氨酸中的应用

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4110641B2 (ja) 1998-11-17 2008-07-02 味の素株式会社 発酵法によるｌ−メチオニンの製造法
JP2000157267A (ja) 1998-11-24 2000-06-13 Ajinomoto Co Inc 変異型ｍｅｔＪ遺伝子及びＬ−メチオニンの製造法
AU2001285844A1 (en) 2000-08-02 2002-02-13 Degussa A.G. Nucleotide sequences which code for the meth gene
EP1656454A4 (en) 2003-07-08 2011-06-22 Novus Int Inc PROCESS FOR METHIONINAL RECOVERY
DE10359594A1 (de) 2003-12-18 2005-07-28 Basf Ag PEF-TU-Expressionseinheiten
DE10359668A1 (de) 2003-12-18 2005-07-14 Basf Ag Verfahren zur Herstellung von Methionin
FR2864967B1 (fr) 2004-01-12 2006-05-19 Metabolic Explorer Sa Microorganisme evolue pour la production de 1,2-propanediol
WO2005111202A1 (en) 2004-05-12 2005-11-24 Metabolic Explorer Recombinant enzyme with altered feedback sensitivity
KR100651220B1 (ko) 2004-06-29 2006-11-29 씨제이 주식회사 Ｌ-메씨오닌 생산 균주 및 상기 균주를 이용한ｌ-메씨오닌의 생산방법
DE102004035065A1 (de) 2004-07-20 2006-02-16 Basf Ag P-ET-TS-Expressionseinheiten
JP4061557B2 (ja) 2005-07-11 2008-03-19 三菱マテリアル株式会社 相変化膜形成用スパッタリングターゲットおよびその製造方法。
CN101223279B (zh) * 2005-07-18 2012-09-05 赢创德固赛有限公司 产生甲硫氨酸的重组微生物
BRPI0620880B1 (pt) * 2006-01-04 2018-10-09 Evonik Degussa Gmbh método para a produção de metionina, pelo cultivo de um microorganismo, e, microorganismo
KR100905381B1 (ko) 2006-07-28 2009-06-30 씨제이제일제당 (주) Ｌ-메치오닌 전구체 생산 균주 및 상기 ｌ-메치오닌전구체로부터의 ｌ-메치오닌 및 유기산의 생산방법
CA2679989C (en) 2007-03-23 2015-07-07 Metabolic Explorer New micro-organisms for the production of 1,2-propanediol obtained by a combination of evolution and rational design
EP2808382B1 (en) 2007-04-11 2016-03-16 CJ CheilJedang Corporation Compositions and methods of producing methionine
WO2009043372A1 (en) * 2007-10-02 2009-04-09 Metabolic Explorer Increasing methionine yield
US9005952B2 (en) * 2008-04-04 2015-04-14 Cj Cheiljedang Corporation Microorganism producing L-methionine precursor and the method of producing L-methionine precursor using the microorganism
US8163532B2 (en) * 2008-05-28 2012-04-24 Evonik Degussa Gmbh Microorganisms with a reactivation system for cob(I)alamin-dependent methionine synthase
WO2010020290A1 (en) 2008-08-22 2010-02-25 Metabolic Explorer Producing methionine without n-acetyl methionine
US8283152B2 (en) 2009-08-28 2012-10-09 Cj Cheiljedang Corporation Microorganism producing O-acetyl-homoserine and the method of producing O-acetyl-homoserine using the microorganism
WO2011073738A1 (en) 2009-12-14 2011-06-23 Metabolic Explorer Use of inducible promoters in the production of methionine
WO2011080301A2 (en) 2009-12-30 2011-07-07 Metabolic Explorer Strains and method for the production of methionine
MX2012007718A (es) 2009-12-30 2012-07-25 Metabolic Explorer Sa Aumento de la produccion de metionina mediante la sobreexpresion de succinato deshidrogenasa.
AR083468A1 (es) 2010-10-25 2013-02-27 Metabolic Explorer Sa Aumento de la disponibilidad de nadph para la produccion de metionina
EP2479279A1 (de) 2011-01-20 2012-07-25 Evonik Degussa GmbH Verfahren zur fermentativen Herstellung schwefelhaltiger Aminosäuren
AR086790A1 (es) 2011-06-29 2014-01-22 Metabolic Explorer Sa Un microorganismo para la produccion de metionina con importacion de glucosa mejorada
US9506093B2 (en) * 2012-06-18 2016-11-29 Metabolic Explorer Recombinant microorganism for the fermentative production of methionine
EP3039153B1 (en) 2013-08-30 2018-08-22 Evonik Degussa GmbH Microorganism for methionine production with improved methionine synthase activity and methionine efflux
CN105658785B (zh) 2013-08-30 2019-12-06 赢创德固赛有限公司 具有增强的甲硫氨酸流出的用于甲硫氨酸生产的微生物

Also Published As

Publication number Publication date
CN108026516A (zh) 2018-05-11
US20180223319A1 (en) 2018-08-09
WO2017025766A1 (en) 2017-02-16
MY184139A (en) 2021-03-22
BR112018002048A2 (pt) 2018-09-18
EP3331998B1 (en) 2020-06-24
EP3331998A1 (en) 2018-06-13

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