DK3334412T3 - Farmaceutisk sammensætning, som omfatter elektrohydrodynamisk opnåede fibre, hvilken sammensætning har forøget opholdstid på påføringsstedet - Google Patents

Farmaceutisk sammensætning, som omfatter elektrohydrodynamisk opnåede fibre, hvilken sammensætning har forøget opholdstid på påføringsstedet Download PDF

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Publication number
DK3334412T3
DK3334412T3 DK16797943.4T DK16797943T DK3334412T3 DK 3334412 T3 DK3334412 T3 DK 3334412T3 DK 16797943 T DK16797943 T DK 16797943T DK 3334412 T3 DK3334412 T3 DK 3334412T3
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Denmark
Prior art keywords
electrohydrodynamic
residence
fibers
acquired
increased
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DK16797943.4T
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Danish (da)
English (en)
Inventor
Jens Hansen
Martin Eduardo Santocildes Romero
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Afyx Therapeutics As
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Publication of DK3334412T3 publication Critical patent/DK3334412T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nanotechnology (AREA)
  • Dermatology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nonwoven Fabrics (AREA)
  • Spinning Methods And Devices For Manufacturing Artificial Fibers (AREA)
DK16797943.4T 2015-11-19 2016-11-18 Farmaceutisk sammensætning, som omfatter elektrohydrodynamisk opnåede fibre, hvilken sammensætning har forøget opholdstid på påføringsstedet DK3334412T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201570745 2015-11-19
PCT/EP2016/078151 WO2017085264A1 (en) 2015-11-19 2016-11-18 A pharmaceutical composition comprising electrohydrodynamically obtained fibres, the composition having improved residence time on the application site

Publications (1)

Publication Number Publication Date
DK3334412T3 true DK3334412T3 (da) 2022-01-17

Family

ID=58718438

Family Applications (1)

Application Number Title Priority Date Filing Date
DK16797943.4T DK3334412T3 (da) 2015-11-19 2016-11-18 Farmaceutisk sammensætning, som omfatter elektrohydrodynamisk opnåede fibre, hvilken sammensætning har forøget opholdstid på påføringsstedet

Country Status (17)

Country Link
US (4) US20180221295A1 (https=)
EP (1) EP3334412B1 (https=)
JP (2) JP6606279B2 (https=)
KR (3) KR102435996B1 (https=)
CN (1) CN108135833B (https=)
AU (2) AU2016358266B2 (https=)
BR (1) BR112018001978A2 (https=)
CA (1) CA2993377C (https=)
DK (1) DK3334412T3 (https=)
ES (1) ES2900741T3 (https=)
IL (1) IL258093B (https=)
MX (1) MX391778B (https=)
MY (1) MY167777A (https=)
NZ (1) NZ740615A (https=)
RU (2) RU2019129082A (https=)
SG (1) SG10201913222XA (https=)
WO (1) WO2017085264A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2019125715A (ru) 2017-01-23 2021-02-24 Афикс Терапьютикс А/С Способ изготовления двухслойного продукта на основе электроспряденных волокон
BR112019014732A2 (pt) 2017-01-23 2020-03-10 Afyx Therapeutics A/S Método para a preparação de fibras eletrofiadas com um alto teor de uma substância bioadesiva
WO2021050532A1 (en) * 2019-09-09 2021-03-18 Afyx Therapeutics A/S Compositions for treating fungal infections
CA3157209A1 (en) 2019-10-08 2021-04-15 Afyx Therapeutics A/S Compositions for the delivery of proteins
EP4121017A4 (en) * 2020-03-17 2024-07-03 Blaesi, Aron H. EXPANDABLE, MULTI-EXCIPIENT STRUCTURED DOSAGE FORM FOR EXTENDED ACTIVE INGREDIENT RELEASE
CA3203975A1 (en) 2020-12-03 2022-06-09 Battelle Memorial Institute Polymer nanoparticle and dna nanostructure compositions and methods for non-viral delivery
CA3216359A1 (en) 2021-04-07 2022-10-13 Battelle Memorial Institute Rapid design, build, test, and learn technologies for identifying and using non-viral carriers
EP4108231A1 (en) * 2021-06-25 2022-12-28 Johann-Wolfgang-Goethe-Universität Frankfurt am Main In-situ dissolving electrospun polymer fibers for ocular drug delivery
PL4124336T3 (pl) * 2021-07-30 2024-02-26 Cannamedical Pharma Gmbh Plaster przezśluzówkowy obejmujący kannabinoid i/lub opioid
AU2022395509A1 (en) 2021-11-23 2024-06-13 Afyx Development A/S Mucosal patches and methods of use thereof
WO2024160792A1 (en) * 2023-01-30 2024-08-08 Cannamedical Pharma Gmbh Improved transmucosal patch comprising a cannabinoid and/or an opioid
CN121843694A (zh) 2023-09-06 2026-04-10 阿费克斯发展有限公司 用于治疗及预防口腔癌的组合物与方法
AU2024353375A1 (en) 2023-09-29 2026-04-09 Battelle Memorial Institute Polymer nanoparticle compositions for in vivo expression of polypeptides
WO2025122954A1 (en) 2023-12-08 2025-06-12 Battelle Memorial Institute Use of dna origami nanostructures for molecular information based data storage systems
KR20250176151A (ko) * 2024-06-11 2025-12-18 주식회사 아이메디텍 중재시술용 지혈 의료용 나노섬유 제조방법 및 이에 의한 의료용 나노섬유

Family Cites Families (13)

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JPS61280423A (ja) 1985-06-05 1986-12-11 Kiyuukiyuu Yakuhin Kogyo Kk 口腔内粘膜貼付剤
US6753454B1 (en) * 1999-10-08 2004-06-22 The University Of Akron Electrospun fibers and an apparatus therefor
JP2003521493A (ja) * 2000-01-28 2003-07-15 スミスクライン・ビーチャム・コーポレイション 電気紡糸された医薬組成物
US7309498B2 (en) * 2001-10-10 2007-12-18 Belenkaya Bronislava G Biodegradable absorbents and methods of preparation
US20030017208A1 (en) * 2002-07-19 2003-01-23 Francis Ignatious Electrospun pharmaceutical compositions
TW200410714A (en) * 2002-08-07 2004-07-01 Smithkline Beecham Corp Electrospun amorphous pharmaceutical compositions
CA2495181A1 (en) * 2002-08-13 2004-02-19 Medtronic, Inc. Active agent delivery system including a hydrophilic polymer, medical device, and method
US9233080B2 (en) * 2008-03-27 2016-01-12 Agigma, Inc. Compositions and methods for the delivery of agents
WO2013165604A1 (en) * 2012-05-02 2013-11-07 Massachusetts Institute Of Technology Electroprocessing of active pharmaceutical ingredients
CN102670483B (zh) * 2012-05-09 2014-04-02 上海交通大学 一种用于高血脂症治疗的静电纺丝纤维膜制剂及其制备方法
US20150290354A1 (en) * 2012-10-22 2015-10-15 North Carolina State University Nonwoven fiber materials
EP2810645B1 (en) * 2013-06-06 2017-05-24 A. Sezai Sarac New Drug Delivery System
CA2950821C (en) 2014-06-10 2024-02-06 Dermtreat Aps Compositions comprising electrohydrodynamically obtained fibres for administration of specific dosages of an active substance to skin or mucosa

Also Published As

Publication number Publication date
CA2993377A1 (en) 2017-05-26
KR20190067280A (ko) 2019-06-14
BR112018001978A2 (pt) 2018-09-18
MX391778B (es) 2025-03-21
RU2019129082A (ru) 2020-04-28
MY167777A (en) 2018-09-25
CN108135833A (zh) 2018-06-08
EP3334412B1 (en) 2021-10-20
AU2018220020B2 (en) 2020-05-21
HK1256209A1 (en) 2019-09-13
MX2018005206A (es) 2018-08-01
CA2993377C (en) 2019-11-12
US20230285313A1 (en) 2023-09-14
US20180221295A1 (en) 2018-08-09
NZ740615A (en) 2019-06-28
KR20180040704A (ko) 2018-04-20
EP3334412A1 (en) 2018-06-20
US20190254985A1 (en) 2019-08-22
KR102435996B1 (ko) 2022-08-25
RU2018109496A (ru) 2019-09-19
AU2016358266B2 (en) 2018-06-21
RU2018109496A3 (https=) 2019-09-19
KR20190020173A (ko) 2019-02-27
KR102001163B1 (ko) 2019-07-18
IL258093B (en) 2022-03-01
JP6606279B2 (ja) 2019-11-13
JP6929916B2 (ja) 2021-09-01
IL258093A (en) 2018-05-31
ES2900741T3 (es) 2022-03-18
AU2016358266A1 (en) 2018-04-05
AU2018220020C1 (en) 2020-09-17
SG10201913222XA (en) 2020-03-30
JP2018528256A (ja) 2018-09-27
JP2020022787A (ja) 2020-02-13
CN108135833B (zh) 2022-11-29
WO2017085264A1 (en) 2017-05-26
RU2701513C2 (ru) 2019-09-27
AU2018220020A1 (en) 2018-09-06
US20240139117A1 (en) 2024-05-02

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