BR112018001978A2 - composição farmacêutica compreendendo fibras obtidas de forma eletro-hidrodinâ¬mica, composição com tempo de permanência melhorado sobre o local de aplicação - Google Patents

composição farmacêutica compreendendo fibras obtidas de forma eletro-hidrodinâ¬mica, composição com tempo de permanência melhorado sobre o local de aplicação

Info

Publication number
BR112018001978A2
BR112018001978A2 BR112018001978A BR112018001978A BR112018001978A2 BR 112018001978 A2 BR112018001978 A2 BR 112018001978A2 BR 112018001978 A BR112018001978 A BR 112018001978A BR 112018001978 A BR112018001978 A BR 112018001978A BR 112018001978 A2 BR112018001978 A2 BR 112018001978A2
Authority
BR
Brazil
Prior art keywords
composition
residence time
time over
application site
pharmaceutical composition
Prior art date
Application number
BR112018001978A
Other languages
English (en)
Portuguese (pt)
Inventor
Hansen Jens
Eduardo Santocildes Romero Martin
Original Assignee
Dermtreat Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dermtreat Aps filed Critical Dermtreat Aps
Publication of BR112018001978A2 publication Critical patent/BR112018001978A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0092—Hollow drug-filled fibres, tubes of the core-shell type, coated fibres, coated rods, microtubules or nanotubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nanotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Dermatology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nonwoven Fabrics (AREA)
  • Spinning Methods And Devices For Manufacturing Artificial Fibers (AREA)
BR112018001978A 2015-11-19 2016-11-18 composição farmacêutica compreendendo fibras obtidas de forma eletro-hidrodinâ¬mica, composição com tempo de permanência melhorado sobre o local de aplicação BR112018001978A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201570745 2015-11-19
PCT/EP2016/078151 WO2017085264A1 (en) 2015-11-19 2016-11-18 A pharmaceutical composition comprising electrohydrodynamically obtained fibres, the composition having improved residence time on the application site

Publications (1)

Publication Number Publication Date
BR112018001978A2 true BR112018001978A2 (pt) 2018-09-18

Family

ID=58718438

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018001978A BR112018001978A2 (pt) 2015-11-19 2016-11-18 composição farmacêutica compreendendo fibras obtidas de forma eletro-hidrodinâ¬mica, composição com tempo de permanência melhorado sobre o local de aplicação

Country Status (17)

Country Link
US (4) US20180221295A1 (https=)
EP (1) EP3334412B1 (https=)
JP (2) JP6606279B2 (https=)
KR (3) KR20190067280A (https=)
CN (1) CN108135833B (https=)
AU (2) AU2016358266B2 (https=)
BR (1) BR112018001978A2 (https=)
CA (1) CA2993377C (https=)
DK (1) DK3334412T3 (https=)
ES (1) ES2900741T3 (https=)
IL (1) IL258093B (https=)
MX (1) MX391778B (https=)
MY (1) MY167777A (https=)
NZ (1) NZ740615A (https=)
RU (2) RU2701513C2 (https=)
SG (1) SG10201913222XA (https=)
WO (1) WO2017085264A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102592782B1 (ko) 2017-01-23 2023-10-20 에이에프와이엑스 테라퓨틱스 에스에이 전기방사 섬유에 기반한 2층 제품의 제조 방법
IL268185B2 (en) 2017-01-23 2024-01-01 Afyx Therapeutics As Method for preparing electrospun fibers with a high content of a bioadhesive substance
WO2021050532A1 (en) * 2019-09-09 2021-03-18 Afyx Therapeutics A/S Compositions for treating fungal infections
EP4041190A1 (en) 2019-10-08 2022-08-17 Afyx Therapeutics A/S Compositions for the delivery of proteins
CA3171147A1 (en) * 2020-03-17 2021-09-23 Nannaji Saka Expandable, multi-excipient structured dosage form for prolonged drug release
CN116887866A (zh) 2020-12-03 2023-10-13 巴特尔纪念研究院 聚合物纳米颗粒和dna纳米结构组合物及用于非病毒递送的方法
WO2022216977A1 (en) 2021-04-07 2022-10-13 Batelle Memorial Institute Rapid design, build, test, and learn technologies for identifying and using non-viral carriers
EP4108231A1 (en) * 2021-06-25 2022-12-28 Johann-Wolfgang-Goethe-Universität Frankfurt am Main In-situ dissolving electrospun polymer fibers for ocular drug delivery
ES2962999T3 (es) * 2021-07-30 2024-03-22 Cannamedical Pharma Gmbh Parche transmucoso que comprende un cannabinoide y/o un opiáceo
AU2022395509A1 (en) 2021-11-23 2024-06-13 Afyx Development A/S Mucosal patches and methods of use thereof
WO2024160792A1 (en) * 2023-01-30 2024-08-08 Cannamedical Pharma Gmbh Improved transmucosal patch comprising a cannabinoid and/or an opioid
CN121843694A (zh) 2023-09-06 2026-04-10 阿费克斯发展有限公司 用于治疗及预防口腔癌的组合物与方法
WO2025072751A1 (en) 2023-09-29 2025-04-03 Battelle Memorial Institute Polymer nanoparticle compositions for in vivo expression of polypeptides
US12441996B2 (en) 2023-12-08 2025-10-14 Battelle Memorial Institute Use of DNA origami nanostructures for molecular information based data storage systems
WO2025258992A1 (ko) * 2024-06-11 2025-12-18 주식회사 아이메디텍 중재시술용 지혈 의료용 나노섬유 제조방법 및 이에 의한 의료용 나노섬유

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61280423A (ja) 1985-06-05 1986-12-11 Kiyuukiyuu Yakuhin Kogyo Kk 口腔内粘膜貼付剤
US6753454B1 (en) * 1999-10-08 2004-06-22 The University Of Akron Electrospun fibers and an apparatus therefor
WO2001054667A1 (en) * 2000-01-28 2001-08-02 Smithkline Beecham Corporation Electrospun pharmaceutical compositions
US7309498B2 (en) * 2001-10-10 2007-12-18 Belenkaya Bronislava G Biodegradable absorbents and methods of preparation
US20030017208A1 (en) * 2002-07-19 2003-01-23 Francis Ignatious Electrospun pharmaceutical compositions
TW200410714A (en) * 2002-08-07 2004-07-01 Smithkline Beecham Corp Electrospun amorphous pharmaceutical compositions
AU2003265446A1 (en) * 2002-08-13 2004-02-25 Medtronic, Inc. Active agent delivery system including a hydrophilic polymer, medical device, and method
CA2719637C (en) * 2008-03-27 2014-10-28 Agigma, Inc. Methods and compositions for the delivery of agents
WO2013165604A1 (en) * 2012-05-02 2013-11-07 Massachusetts Institute Of Technology Electroprocessing of active pharmaceutical ingredients
CN102670483B (zh) * 2012-05-09 2014-04-02 上海交通大学 一种用于高血脂症治疗的静电纺丝纤维膜制剂及其制备方法
WO2014066297A1 (en) * 2012-10-22 2014-05-01 North Carolina State University Nonwoven fiber materials
EP2810645B1 (en) * 2013-06-06 2017-05-24 A. Sezai Sarac New Drug Delivery System
NZ746573A (en) 2014-06-10 2023-07-28 Afyx Therapeutics As Compositions comprising electrohydrodynamically obtained fibres for administration of specific dosages of an active substance to skin or mucosa

Also Published As

Publication number Publication date
JP2020022787A (ja) 2020-02-13
RU2019129082A (ru) 2020-04-28
KR20180040704A (ko) 2018-04-20
SG10201913222XA (en) 2020-03-30
EP3334412A1 (en) 2018-06-20
JP6929916B2 (ja) 2021-09-01
EP3334412B1 (en) 2021-10-20
CN108135833B (zh) 2022-11-29
KR20190020173A (ko) 2019-02-27
AU2018220020B2 (en) 2020-05-21
MY167777A (en) 2018-09-25
MX391778B (es) 2025-03-21
NZ740615A (en) 2019-06-28
CN108135833A (zh) 2018-06-08
MX2018005206A (es) 2018-08-01
US20240139117A1 (en) 2024-05-02
IL258093B (en) 2022-03-01
AU2016358266B2 (en) 2018-06-21
DK3334412T3 (da) 2022-01-17
AU2018220020A1 (en) 2018-09-06
RU2701513C2 (ru) 2019-09-27
WO2017085264A1 (en) 2017-05-26
KR102001163B1 (ko) 2019-07-18
US20180221295A1 (en) 2018-08-09
CA2993377A1 (en) 2017-05-26
RU2018109496A (ru) 2019-09-19
ES2900741T3 (es) 2022-03-18
US20190254985A1 (en) 2019-08-22
JP2018528256A (ja) 2018-09-27
HK1256209A1 (en) 2019-09-13
KR102435996B1 (ko) 2022-08-25
AU2018220020C1 (en) 2020-09-17
US20230285313A1 (en) 2023-09-14
KR20190067280A (ko) 2019-06-14
RU2018109496A3 (https=) 2019-09-19
IL258093A (en) 2018-05-31
CA2993377C (en) 2019-11-12
AU2016358266A1 (en) 2018-04-05
JP6606279B2 (ja) 2019-11-13

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Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: DERMTREAT A/S (DK)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B25D Requested change of name of applicant approved

Owner name: AFYX THERAPEUTICS A/S (DK)

B25G Requested change of headquarter approved

Owner name: AFYX THERAPEUTICS A/S (DK)

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements