DK3239304T3 - Højgennemløbsdetektering af molekylære markører baseret på AFLP og sekventering med højt gennemløb - Google Patents
Højgennemløbsdetektering af molekylære markører baseret på AFLP og sekventering med højt gennemløb Download PDFInfo
- Publication number
- DK3239304T3 DK3239304T3 DK17163116.1T DK17163116T DK3239304T3 DK 3239304 T3 DK3239304 T3 DK 3239304T3 DK 17163116 T DK17163116 T DK 17163116T DK 3239304 T3 DK3239304 T3 DK 3239304T3
- Authority
- DK
- Denmark
- Prior art keywords
- throughput
- aflp
- molecular markers
- markers based
- detection
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
- C12Q1/6855—Ligating adaptors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US78870606P | 2006-04-04 | 2006-04-04 | |
US88005207P | 2007-01-12 | 2007-01-12 | |
EP15158621.1A EP2963127B1 (en) | 2006-04-04 | 2007-04-04 | High throughput detection of molecular markers based on restriction fragments |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3239304T3 true DK3239304T3 (da) | 2020-10-26 |
Family
ID=38508899
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK17163116.1T DK3239304T3 (da) | 2006-04-04 | 2007-04-04 | Højgennemløbsdetektering af molekylære markører baseret på AFLP og sekventering med højt gennemløb |
DK07747276.9T DK2002017T3 (da) | 2006-04-04 | 2007-04-04 | Højkapacitet-detektering af molekylære markører baseret på restriktionsfragmenter |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK07747276.9T DK2002017T3 (da) | 2006-04-04 | 2007-04-04 | Højkapacitet-detektering af molekylære markører baseret på restriktionsfragmenter |
Country Status (9)
Country | Link |
---|---|
US (6) | US20090253581A1 (da) |
EP (3) | EP2002017B1 (da) |
JP (2) | JP5389638B2 (da) |
DK (2) | DK3239304T3 (da) |
ES (3) | ES2829295T3 (da) |
HK (2) | HK1219761A1 (da) |
PL (1) | PL2963127T3 (da) |
PT (1) | PT2963127T (da) |
WO (1) | WO2007114693A2 (da) |
Families Citing this family (114)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1885882T3 (da) | 2005-05-10 | 2011-04-11 | State Of Oregon Acting By & Through The State Board Of Higher Eduction On Behalf Of The University O | Fremgangsmåder til kortlægning af polymorfier og polymorfi-mikroarray |
ES2387878T3 (es) | 2005-06-23 | 2012-10-03 | Keygene N.V. | Estrategias para la identificación de alto rendimiento y la detección de polimorfismos |
US10316364B2 (en) | 2005-09-29 | 2019-06-11 | Keygene N.V. | Method for identifying the source of an amplicon |
CA2623539C (en) | 2005-09-29 | 2015-12-15 | Keygene N.V. | High throughput screening of mutagenized populations |
JP5452021B2 (ja) | 2005-12-22 | 2014-03-26 | キージーン ナムローゼ フェンノートシャップ | ハイスループットaflp系多型検出法 |
US9365901B2 (en) | 2008-11-07 | 2016-06-14 | Adaptive Biotechnologies Corp. | Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia |
EP4335932A3 (en) | 2008-11-07 | 2024-06-26 | Adaptive Biotechnologies Corporation | Methods of monitoring conditions by sequence analysis |
US8748103B2 (en) | 2008-11-07 | 2014-06-10 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
US8628927B2 (en) | 2008-11-07 | 2014-01-14 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
US9506119B2 (en) | 2008-11-07 | 2016-11-29 | Adaptive Biotechnologies Corp. | Method of sequence determination using sequence tags |
US9528160B2 (en) | 2008-11-07 | 2016-12-27 | Adaptive Biotechnolgies Corp. | Rare clonotypes and uses thereof |
US8685898B2 (en) | 2009-01-15 | 2014-04-01 | Imdaptive, Inc. | Adaptive immunity profiling and methods for generation of monoclonal antibodies |
CA2750879C (en) * | 2009-01-30 | 2018-05-22 | Oxford Nanopore Technologies Limited | Adaptors for nucleic acid constructs in transmembrane sequencing |
GB2472371B (en) * | 2009-04-24 | 2011-10-26 | Selectamark Security Systems Plc | Synthetic nucleotide containing compositions for use in security marking of property and/or for marking a thief or attacker |
US9085798B2 (en) | 2009-04-30 | 2015-07-21 | Prognosys Biosciences, Inc. | Nucleic acid constructs and methods of use |
EP2248914A1 (en) * | 2009-05-05 | 2010-11-10 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | The use of class IIB restriction endonucleases in 2nd generation sequencing applications |
CA2765949C (en) | 2009-06-25 | 2016-03-29 | Fred Hutchinson Cancer Research Center | Method of measuring adaptive immunity |
US9043160B1 (en) | 2009-11-09 | 2015-05-26 | Sequenta, Inc. | Method of determining clonotypes and clonotype profiles |
US10787701B2 (en) | 2010-04-05 | 2020-09-29 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
PT2556171E (pt) | 2010-04-05 | 2015-12-21 | Prognosys Biosciences Inc | Ensaios biológicos codificados espacialmente |
US20190300945A1 (en) | 2010-04-05 | 2019-10-03 | Prognosys Biosciences, Inc. | Spatially Encoded Biological Assays |
US8766054B2 (en) | 2010-12-08 | 2014-07-01 | Hm.Clause | Phytophthora resistance in sweet peppers |
GB201106254D0 (en) | 2011-04-13 | 2011-05-25 | Frisen Jonas | Method and product |
KR20140050067A (ko) | 2011-07-25 | 2014-04-28 | 옥스포드 나노포어 테크놀로지즈 리미티드 | 막횡단 포어를 사용한 이중 가닥 폴리뉴클레오티드 서열분석을 위한 헤어핀 루프 방법 |
US10385475B2 (en) | 2011-09-12 | 2019-08-20 | Adaptive Biotechnologies Corp. | Random array sequencing of low-complexity libraries |
US9279159B2 (en) | 2011-10-21 | 2016-03-08 | Adaptive Biotechnologies Corporation | Quantification of adaptive immune cell genomes in a complex mixture of cells |
EP2788509B1 (en) | 2011-12-09 | 2018-07-11 | Adaptive Biotechnologies Corporation | Diagnosis of lymphoid malignancies and minimal residual disease detection |
US9499865B2 (en) | 2011-12-13 | 2016-11-22 | Adaptive Biotechnologies Corp. | Detection and measurement of tissue-infiltrating lymphocytes |
CN104334739A (zh) | 2012-01-13 | 2015-02-04 | Data生物有限公司 | 通过新一代测序进行基因分型 |
LT3363901T (lt) | 2012-02-17 | 2021-04-12 | Fred Hutchinson Cancer Research Center | Kompozicijos ir būdai, skirti tiksliam mutacijų nustatymui |
WO2013134162A2 (en) | 2012-03-05 | 2013-09-12 | Sequenta, Inc. | Determining paired immune receptor chains from frequency matched subunits |
HUE051845T2 (hu) | 2012-03-20 | 2021-03-29 | Univ Washington Through Its Center For Commercialization | Módszerek a tömegesen párhuzamos DNS-szekvenálás hibaarányának csökkentésére duplex konszenzus szekvenálással |
SG10201507700VA (en) | 2012-05-08 | 2015-10-29 | Adaptive Biotechnologies Corp | Compositions and method for measuring and calibrating amplification bias in multiplexed pcr reactions |
ES2660027T3 (es) | 2012-10-01 | 2018-03-20 | Adaptive Biotechnologies Corporation | Evaluación de la inmunocompetencia por la diversidad de los receptores de inmunidad adaptativa y caracterización de la clonalidad |
USRE50065E1 (en) | 2012-10-17 | 2024-07-30 | 10X Genomics Sweden Ab | Methods and product for optimising localised or spatial detection of gene expression in a tissue sample |
CN105209634B (zh) | 2013-03-08 | 2020-05-12 | 牛津纳米孔技术公司 | 酶停滞方法 |
GB201314695D0 (en) | 2013-08-16 | 2013-10-02 | Oxford Nanopore Tech Ltd | Method |
DK3013984T3 (da) | 2013-06-25 | 2023-06-06 | Prognosys Biosciences Inc | Metode til bestemmelse af spatiale mønstre i biologiske targets i en prøve |
US9708657B2 (en) | 2013-07-01 | 2017-07-18 | Adaptive Biotechnologies Corp. | Method for generating clonotype profiles using sequence tags |
WO2015134787A2 (en) | 2014-03-05 | 2015-09-11 | Adaptive Biotechnologies Corporation | Methods using randomer-containing synthetic molecules |
US11390921B2 (en) | 2014-04-01 | 2022-07-19 | Adaptive Biotechnologies Corporation | Determining WT-1 specific T cells and WT-1 specific T cell receptors (TCRs) |
US10066265B2 (en) | 2014-04-01 | 2018-09-04 | Adaptive Biotechnologies Corp. | Determining antigen-specific t-cells |
ES2777529T3 (es) | 2014-04-17 | 2020-08-05 | Adaptive Biotechnologies Corp | Cuantificación de genomas de células inmunitarias adaptativas en una mezcla compleja de células |
GB201418159D0 (en) | 2014-10-14 | 2014-11-26 | Oxford Nanopore Tech Ltd | Method |
EP3715455A1 (en) | 2014-10-29 | 2020-09-30 | Adaptive Biotechnologies Corp. | Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from many samples |
US10246701B2 (en) | 2014-11-14 | 2019-04-02 | Adaptive Biotechnologies Corp. | Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture |
US11066705B2 (en) | 2014-11-25 | 2021-07-20 | Adaptive Biotechnologies Corporation | Characterization of adaptive immune response to vaccination or infection using immune repertoire sequencing |
EP3591074B1 (en) | 2015-02-24 | 2024-10-23 | Adaptive Biotechnologies Corp. | Methods for diagnosing infectious disease and determining hla status using immune repertoire sequencing |
EP3277294B1 (en) | 2015-04-01 | 2024-05-15 | Adaptive Biotechnologies Corp. | Method of identifying human compatible t cell receptors specific for an antigenic target |
FI3901281T3 (fi) | 2015-04-10 | 2023-01-31 | Biologisten näytteiden spatiaalisesti eroteltu moninkertainen nukleiinihappoanalyysi | |
EP3387152B1 (en) | 2015-12-08 | 2022-01-26 | Twinstrand Biosciences, Inc. | Improved adapters, methods, and compositions for duplex sequencing |
CN105441572B (zh) * | 2016-01-07 | 2019-10-22 | 南京中医药大学 | 鉴别当归早薹的dna分子标记及其应用 |
GB201609220D0 (en) | 2016-05-25 | 2016-07-06 | Oxford Nanopore Tech Ltd | Method |
JP7343264B2 (ja) | 2016-06-29 | 2023-09-12 | トヨタ自動車株式会社 | Dnaライブラリーの作製方法及びdnaライブラリーを用いたゲノムdna解析方法 |
JP6515884B2 (ja) | 2016-06-29 | 2019-05-22 | トヨタ自動車株式会社 | Dnaプローブの作製方法及びdnaプローブを用いたゲノムdna解析方法 |
US10428325B1 (en) | 2016-09-21 | 2019-10-01 | Adaptive Biotechnologies Corporation | Identification of antigen-specific B cell receptors |
EP3601611B1 (en) * | 2017-03-24 | 2022-01-05 | Life Technologies Corporation | Polynucleotide adapters and methods of use thereof |
WO2018183942A1 (en) | 2017-03-31 | 2018-10-04 | Grail, Inc. | Improved library preparation and use thereof for sequencing-based error correction and/or variant identification |
JP7056012B2 (ja) | 2017-05-19 | 2022-04-19 | トヨタ自動車株式会社 | ランダムプライマーセット、及びこれを用いたdnaライブラリーの作製方法 |
AU2018366213A1 (en) | 2017-11-08 | 2020-05-14 | Twinstrand Biosciences, Inc. | Reagents and adapters for nucleic acid sequencing and methods for making such reagents and adapters |
US11254980B1 (en) | 2017-11-29 | 2022-02-22 | Adaptive Biotechnologies Corporation | Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements |
WO2019121603A1 (en) | 2017-12-18 | 2019-06-27 | Keygene N.V. | Chemical mutagenesis of cassava |
JP7047373B2 (ja) | 2017-12-25 | 2022-04-05 | トヨタ自動車株式会社 | 次世代シーケンサー用プライマー並びにその製造方法、次世代シーケンサー用プライマーを用いたdnaライブラリー並びにその製造方法、及びdnaライブラリーを用いたゲノムdna解析方法 |
GB201807793D0 (en) | 2018-05-14 | 2018-06-27 | Oxford Nanopore Tech Ltd | Method |
KR20210059694A (ko) | 2018-07-12 | 2021-05-25 | 트윈스트랜드 바이오사이언시스, 인코포레이티드 | 게놈 편집, 클론 팽창 및 연관된 분야를 규명하기 위한 방법 및 시약 |
US11519033B2 (en) | 2018-08-28 | 2022-12-06 | 10X Genomics, Inc. | Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample |
EP3894587A1 (en) | 2018-12-10 | 2021-10-20 | 10X Genomics, Inc. | Resolving spatial arrays by proximity-based deconvolution |
US11649485B2 (en) | 2019-01-06 | 2023-05-16 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
US11926867B2 (en) | 2019-01-06 | 2024-03-12 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
WO2020169830A1 (en) | 2019-02-21 | 2020-08-27 | Keygene N.V. | Genotyping of polyploids |
WO2020243579A1 (en) | 2019-05-30 | 2020-12-03 | 10X Genomics, Inc. | Methods of detecting spatial heterogeneity of a biological sample |
EP4025711A2 (en) | 2019-11-08 | 2022-07-13 | 10X Genomics, Inc. | Enhancing specificity of analyte binding |
WO2021091611A1 (en) | 2019-11-08 | 2021-05-14 | 10X Genomics, Inc. | Spatially-tagged analyte capture agents for analyte multiplexing |
WO2021116371A1 (en) | 2019-12-12 | 2021-06-17 | Keygene N.V. | Semi-solid state nucleic acid manipulation |
JP2023506631A (ja) | 2019-12-20 | 2023-02-17 | キージーン ナムローゼ フェンノートシャップ | 共有結合で閉端された核酸分子末端を使用したngsライブラリー調製 |
EP4424843A3 (en) | 2019-12-23 | 2024-09-25 | 10X Genomics, Inc. | Methods for spatial analysis using rna-templated ligation |
WO2021133842A1 (en) | 2019-12-23 | 2021-07-01 | 10X Genomics, Inc. | Compositions and methods for using fixed biological samples in partition-based assays |
US11702693B2 (en) | 2020-01-21 | 2023-07-18 | 10X Genomics, Inc. | Methods for printing cells and generating arrays of barcoded cells |
US11732299B2 (en) | 2020-01-21 | 2023-08-22 | 10X Genomics, Inc. | Spatial assays with perturbed cells |
US11821035B1 (en) | 2020-01-29 | 2023-11-21 | 10X Genomics, Inc. | Compositions and methods of making gene expression libraries |
US12076701B2 (en) | 2020-01-31 | 2024-09-03 | 10X Genomics, Inc. | Capturing oligonucleotides in spatial transcriptomics |
US12110541B2 (en) | 2020-02-03 | 2024-10-08 | 10X Genomics, Inc. | Methods for preparing high-resolution spatial arrays |
US11898205B2 (en) | 2020-02-03 | 2024-02-13 | 10X Genomics, Inc. | Increasing capture efficiency of spatial assays |
US11732300B2 (en) | 2020-02-05 | 2023-08-22 | 10X Genomics, Inc. | Increasing efficiency of spatial analysis in a biological sample |
US11835462B2 (en) | 2020-02-11 | 2023-12-05 | 10X Genomics, Inc. | Methods and compositions for partitioning a biological sample |
US11211144B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Methods and systems for refining copy number variation in a liquid biopsy assay |
US11475981B2 (en) | 2020-02-18 | 2022-10-18 | Tempus Labs, Inc. | Methods and systems for dynamic variant thresholding in a liquid biopsy assay |
US11211147B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing |
US11891654B2 (en) | 2020-02-24 | 2024-02-06 | 10X Genomics, Inc. | Methods of making gene expression libraries |
US11926863B1 (en) | 2020-02-27 | 2024-03-12 | 10X Genomics, Inc. | Solid state single cell method for analyzing fixed biological cells |
US11768175B1 (en) | 2020-03-04 | 2023-09-26 | 10X Genomics, Inc. | Electrophoretic methods for spatial analysis |
CN111304341A (zh) * | 2020-04-10 | 2020-06-19 | 西北民族大学 | 一种鉴定食品中猪源性成分的pcr-aflp方法 |
CN115916999A (zh) | 2020-04-22 | 2023-04-04 | 10X基因组学有限公司 | 用于使用靶向rna耗竭进行空间分析的方法 |
AU2021275906A1 (en) | 2020-05-22 | 2022-12-22 | 10X Genomics, Inc. | Spatial analysis to detect sequence variants |
EP4414459A3 (en) | 2020-05-22 | 2024-09-18 | 10X Genomics, Inc. | Simultaneous spatio-temporal measurement of gene expression and cellular activity |
WO2021242834A1 (en) | 2020-05-26 | 2021-12-02 | 10X Genomics, Inc. | Method for resetting an array |
EP4025692A2 (en) | 2020-06-02 | 2022-07-13 | 10X Genomics, Inc. | Nucleic acid library methods |
AU2021283184A1 (en) | 2020-06-02 | 2023-01-05 | 10X Genomics, Inc. | Spatial transcriptomics for antigen-receptors |
US12031177B1 (en) | 2020-06-04 | 2024-07-09 | 10X Genomics, Inc. | Methods of enhancing spatial resolution of transcripts |
WO2021252499A1 (en) | 2020-06-08 | 2021-12-16 | 10X Genomics, Inc. | Methods of determining a surgical margin and methods of use thereof |
EP4165207B1 (en) | 2020-06-10 | 2024-09-25 | 10X Genomics, Inc. | Methods for determining a location of an analyte in a biological sample |
EP4450639A2 (en) | 2020-06-25 | 2024-10-23 | 10X Genomics, Inc. | Spatial analysis of dna methylation |
US11981960B1 (en) | 2020-07-06 | 2024-05-14 | 10X Genomics, Inc. | Spatial analysis utilizing degradable hydrogels |
US11761038B1 (en) | 2020-07-06 | 2023-09-19 | 10X Genomics, Inc. | Methods for identifying a location of an RNA in a biological sample |
US11981958B1 (en) | 2020-08-20 | 2024-05-14 | 10X Genomics, Inc. | Methods for spatial analysis using DNA capture |
US11926822B1 (en) | 2020-09-23 | 2024-03-12 | 10X Genomics, Inc. | Three-dimensional spatial analysis |
US11827935B1 (en) | 2020-11-19 | 2023-11-28 | 10X Genomics, Inc. | Methods for spatial analysis using rolling circle amplification and detection probes |
AU2021409136A1 (en) | 2020-12-21 | 2023-06-29 | 10X Genomics, Inc. | Methods, compositions, and systems for capturing probes and/or barcodes |
WO2022178267A2 (en) | 2021-02-19 | 2022-08-25 | 10X Genomics, Inc. | Modular assay support devices |
EP4301870A1 (en) | 2021-03-18 | 2024-01-10 | 10X Genomics, Inc. | Multiplex capture of gene and protein expression from a biological sample |
EP4347879A1 (en) | 2021-06-03 | 2024-04-10 | 10X Genomics, Inc. | Methods, compositions, kits, and systems for enhancing analyte capture for spatial analysis |
EP4196605A1 (en) | 2021-09-01 | 2023-06-21 | 10X Genomics, Inc. | Methods, compositions, and kits for blocking a capture probe on a spatial array |
WO2024121354A1 (en) | 2022-12-08 | 2024-06-13 | Keygene N.V. | Duplex sequencing with covalently closed dna ends |
WO2024209000A1 (en) | 2023-04-04 | 2024-10-10 | Keygene N.V. | Linkers for duplex sequencing |
Family Cites Families (85)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0456721A4 (en) | 1989-01-31 | 1992-06-03 | University Of Miami | Microdissection and amplification of chromosomal dna |
JP3236295B2 (ja) | 1991-09-24 | 2001-12-10 | ケイヘーネ・エヌ・ベー | 選択的な制限断片増幅:一般的なdnaフィンガプリント法 |
US20100267023A1 (en) * | 1992-09-24 | 2010-10-21 | Keygene N.V. | Selective restriction fragment amplification: fingerprinting |
WO1995019697A1 (en) | 1994-01-21 | 1995-07-27 | North Carolina State University | Methods for within family selection in woody perennials using genetic markers |
EG23907A (en) | 1994-08-01 | 2007-12-30 | Delta & Pine Land Co | Control of plant gene expression |
US6013445A (en) | 1996-06-06 | 2000-01-11 | Lynx Therapeutics, Inc. | Massively parallel signature sequencing by ligation of encoded adaptors |
DE69507646T2 (de) * | 1994-11-28 | 1999-09-16 | E.I. Du Pont De Nemours And Co., Wilmington | Mikrosatelliteverbindung für detektion genetisches polymorphismen |
US5565340A (en) | 1995-01-27 | 1996-10-15 | Clontech Laboratories, Inc. | Method for suppressing DNA fragment amplification during PCR |
AU6024598A (en) * | 1997-01-10 | 1998-08-03 | Pioneer Hi-Bred International, Inc. | Hybridization-based genetic amplification and analysis |
US6090556A (en) | 1997-04-07 | 2000-07-18 | Japan Science & Technology Corporation | Method for quantitatively determining the expression of a gene |
ES2163271T3 (es) | 1997-05-13 | 2002-01-16 | Azign Bioscience As | Procedimiento para clonar arnm y visualizar transcriptores diferencialmente expresados (dodets). |
ATE369439T1 (de) | 1997-12-15 | 2007-08-15 | Csl Behring Gmbh | Markierter primer, geeignet für die detektion von nukleinsäuren |
CA2273616A1 (en) | 1998-06-08 | 1999-12-08 | The Board Of Trustees Of The Leland Stanford Junior University | Method for parallel screening of allelic variation |
ATE244771T1 (de) | 1998-07-29 | 2003-07-15 | Keygene Nv | Verfahren zur erkennung von nukleinsäuremethylierungen durch aflp |
GB0002310D0 (en) | 2000-02-01 | 2000-03-22 | Solexa Ltd | Polynucleotide sequencing |
IL141148A0 (en) | 1998-07-30 | 2002-02-10 | Solexa Ltd | Arrayed biomolecules and their use in sequencing |
US6232067B1 (en) * | 1998-08-17 | 2001-05-15 | The Perkin-Elmer Corporation | Adapter directed expression analysis |
US6703228B1 (en) | 1998-09-25 | 2004-03-09 | Massachusetts Institute Of Technology | Methods and products related to genotyping and DNA analysis |
EP1001037A3 (en) | 1998-09-28 | 2003-10-01 | Whitehead Institute For Biomedical Research | Pre-selection and isolation of single nucleotide polymorphisms |
AU2144000A (en) | 1998-10-27 | 2000-05-15 | Affymetrix, Inc. | Complexity management and analysis of genomic dna |
US6480791B1 (en) * | 1998-10-28 | 2002-11-12 | Michael P. Strathmann | Parallel methods for genomic analysis |
CA2348696A1 (en) | 1998-11-06 | 2000-05-18 | Solexa Ltd. | A method for reproducing molecular arrays |
WO2000040755A2 (en) | 1999-01-06 | 2000-07-13 | Cornell Research Foundation, Inc. | Method for accelerating identification of single nucleotide polymorphisms and alignment of clones in genomic sequencing |
US20040029155A1 (en) | 1999-01-08 | 2004-02-12 | Curagen Corporation | Method for identifying a biomolecule |
DE19911130A1 (de) | 1999-03-12 | 2000-09-21 | Hager Joerg | Verfahren zur Identifikation chromosomaler Regionen und Gene |
WO2000058507A1 (en) | 1999-03-30 | 2000-10-05 | Solexa Ltd. | Polynucleotide sequencing |
EP1190092A2 (en) * | 1999-04-06 | 2002-03-27 | Yale University | Fixed address analysis of sequence tags |
WO2000061801A2 (en) | 1999-04-09 | 2000-10-19 | Keygene N.V. | METHOD FOR THE DETECTION AND/OR ANALYSIS, BY MEANS OF PRIMER EXTENSION TECHNIQUES, OF SINGLE NUCLEOTIDE POLYMORPHISMS IN RESTRICTION FRAGMENTS, IN PARTICULAR IN AMPLIFIED RESTRICTION FRAGMENTS GENERATED USING AFLP$m(3) |
US20020119448A1 (en) | 1999-06-23 | 2002-08-29 | Joseph A. Sorge | Methods of enriching for and identifying polymorphisms |
US20030204075A9 (en) | 1999-08-09 | 2003-10-30 | The Snp Consortium | Identification and mapping of single nucleotide polymorphisms in the human genome |
WO2001021840A2 (en) | 1999-09-23 | 2001-03-29 | Gene Logic, Inc. | Indexing populations |
EP1218543A2 (en) | 1999-09-29 | 2002-07-03 | Solexa Ltd. | Polynucleotide sequencing |
US6287778B1 (en) | 1999-10-19 | 2001-09-11 | Affymetrix, Inc. | Allele detection using primer extension with sequence-coded identity tags |
US6958225B2 (en) | 1999-10-27 | 2005-10-25 | Affymetrix, Inc. | Complexity management of genomic DNA |
AU1413601A (en) | 1999-11-19 | 2001-06-04 | Takara Bio Inc. | Method of amplifying nucleic acids |
GB0002389D0 (en) | 2000-02-02 | 2000-03-22 | Solexa Ltd | Molecular arrays |
WO2001075167A1 (en) | 2000-03-31 | 2001-10-11 | Fred Hutchinson Cancer Research Center | Reverse genetic strategy for identifying functional mutations in genes of known sequence |
US7217516B2 (en) | 2000-05-15 | 2007-05-15 | Keygene N.V. | Methods and kits comprising AFLP primers, and ramp primers with a part complementary to a compound microsatellite repeat and an anchor part complementary to nucleotides adjacent to the repeat |
US7300751B2 (en) | 2000-06-30 | 2007-11-27 | Syngenta Participations Ag | Method for identification of genetic markers |
AU2002246612B2 (en) | 2000-10-24 | 2007-11-01 | The Board Of Trustees Of The Leland Stanford Junior University | Direct multiplex characterization of genomic DNA |
AU2002231934A1 (en) | 2001-01-30 | 2002-08-12 | Solexa Ltd. | Arrayed polynucleotides and their use in genome analysis |
US20040053236A1 (en) * | 2001-03-30 | 2004-03-18 | Mccallum Claire M. | Reverse genetic strategy for identifying functional mutations in genes of known sequences |
CA2444994A1 (en) | 2001-04-20 | 2002-10-31 | Karolinska Innovations Ab | Methods for high throughput genome analysis using restriction site tagged microarrays |
US20030096268A1 (en) | 2001-07-06 | 2003-05-22 | Michael Weiner | Method for isolation of independent, parallel chemical micro-reactions using a porous filter |
GB0119719D0 (en) | 2001-08-13 | 2001-10-03 | Solexa Ltd | DNA sequence analysis |
US6902921B2 (en) | 2001-10-30 | 2005-06-07 | 454 Corporation | Sulfurylase-luciferase fusion proteins and thermostable sulfurylase |
US7057026B2 (en) | 2001-12-04 | 2006-06-06 | Solexa Limited | Labelled nucleotides |
US6815167B2 (en) | 2002-04-25 | 2004-11-09 | Geneohm Sciences | Amplification of DNA to produce single-stranded product of defined sequence and length |
US20070065816A1 (en) | 2002-05-17 | 2007-03-22 | Affymetrix, Inc. | Methods for genotyping |
US7108976B2 (en) | 2002-06-17 | 2006-09-19 | Affymetrix, Inc. | Complexity management of genomic DNA by locus specific amplification |
AU2003243720A1 (en) * | 2002-06-21 | 2004-01-06 | Bayer Bioscience N.V. | Method for detecting foreign dna in a host genome |
SI3363809T1 (sl) | 2002-08-23 | 2020-08-31 | Illumina Cambridge Limited | Modificirani nukleotidi za polinukleotidno sekvenciranje |
PT2119722T (pt) | 2002-08-23 | 2016-12-12 | Illumina Cambridge Ltd | Nucleótidos marcados |
WO2004022758A1 (en) | 2002-09-05 | 2004-03-18 | Plant Bioscience Limited | Genome partitioning |
US20040157238A1 (en) | 2002-09-20 | 2004-08-12 | Quinn John J. | Method for detection of multiple nucleic acid sequence variations |
US20060094016A1 (en) | 2002-12-02 | 2006-05-04 | Niall Gormley | Determination of methylation of nucleic acid sequences |
MXPA05006633A (es) | 2002-12-18 | 2006-05-25 | Third Wave Tech Inc | Deteccion de pequenos acidos nucleicos. |
JP2004208586A (ja) | 2002-12-27 | 2004-07-29 | Wakunaga Pharmaceut Co Ltd | Hlaの検出 |
EP1581661B1 (en) | 2003-01-10 | 2012-09-12 | Keygene N.V. | Aflp-based method for integrating physical and genetic maps |
EP2159285B1 (en) | 2003-01-29 | 2012-09-26 | 454 Life Sciences Corporation | Methods of amplifying and sequencing nucleic acids |
GB0304371D0 (en) | 2003-02-26 | 2003-04-02 | Solexa Ltd | DNA Sequence analysis |
CN1791682B (zh) | 2003-02-26 | 2013-05-22 | 凯利达基因组股份有限公司 | 通过杂交进行的随机阵列dna分析 |
JP4888876B2 (ja) | 2003-06-13 | 2012-02-29 | 田平 武 | アルツハイマー病の治療のための組換えアデノ随伴ウィルスベクター |
GB0320059D0 (en) | 2003-08-27 | 2003-10-01 | Solexa Ltd | A method of sequencing |
WO2005026686A2 (en) | 2003-09-09 | 2005-03-24 | Compass Genetics, Llc | Multiplexed analytical platform |
WO2005040400A2 (en) | 2003-10-24 | 2005-05-06 | Mmi Genomics, Inc. | Methods and systems for inferring traits to manage non-beef livestock |
GB0326073D0 (en) | 2003-11-07 | 2003-12-10 | Solexa Ltd | Improvements in or relating to polynucleotide arrays |
EP3175914A1 (en) | 2004-01-07 | 2017-06-07 | Illumina Cambridge Limited | Improvements in or relating to molecular arrays |
GB0400584D0 (en) | 2004-01-12 | 2004-02-11 | Solexa Ltd | Nucleic acid chacterisation |
GB0400974D0 (en) | 2004-01-16 | 2004-02-18 | Solexa Ltd | Multiple inexact matching |
US20050233354A1 (en) * | 2004-01-22 | 2005-10-20 | Affymetrix, Inc. | Genotyping degraded or mitochandrial DNA samples |
GB0402895D0 (en) | 2004-02-10 | 2004-03-17 | Solexa Ltd | Arrayed polynucleotides |
DE602005018166D1 (de) | 2004-02-12 | 2010-01-21 | Population Genetics Technologi | Genetische analyse mittels sequenzspezifischem sortieren |
WO2006019407A2 (en) | 2004-02-18 | 2006-02-23 | The Trustees Of Boston University | Method for detecting and quantifying rare mutations/polymorphisms |
EP1574585A1 (en) | 2004-03-12 | 2005-09-14 | Plant Research International B.V. | Method for selective amplification of DNA fragments for genetic fingerprinting |
US7220549B2 (en) | 2004-12-30 | 2007-05-22 | Helicos Biosciences Corporation | Stabilizing a nucleic acid for nucleic acid sequencing |
US7393665B2 (en) | 2005-02-10 | 2008-07-01 | Population Genetics Technologies Ltd | Methods and compositions for tagging and identifying polynucleotides |
US7407757B2 (en) | 2005-02-10 | 2008-08-05 | Population Genetics Technologies | Genetic analysis by sequence-specific sorting |
DK1885882T3 (da) | 2005-05-10 | 2011-04-11 | State Of Oregon Acting By & Through The State Board Of Higher Eduction On Behalf Of The University O | Fremgangsmåder til kortlægning af polymorfier og polymorfi-mikroarray |
ES2387878T3 (es) | 2005-06-23 | 2012-10-03 | Keygene N.V. | Estrategias para la identificación de alto rendimiento y la detección de polimorfismos |
DE602006013831D1 (de) | 2005-06-23 | 2010-06-02 | Keygene Nv | Verbesserte strategien zur sequenzierung komplexer genome unter verwendung von sequenziertechniken mit hohem durchsatz |
US20070020640A1 (en) | 2005-07-21 | 2007-01-25 | Mccloskey Megan L | Molecular encoding of nucleic acid templates for PCR and other forms of sequence analysis |
CA2623539C (en) | 2005-09-29 | 2015-12-15 | Keygene N.V. | High throughput screening of mutagenized populations |
WO2007055568A1 (en) | 2005-11-14 | 2007-05-18 | Keygene N.V. | Method for high throughput screening of transposon tagging populations and massive parallel sequence identification of insertion sites |
WO2007087312A2 (en) | 2006-01-23 | 2007-08-02 | Population Genetics Technologies Ltd. | Molecular counting |
-
2007
- 2007-04-04 EP EP07747276.9A patent/EP2002017B1/en active Active
- 2007-04-04 EP EP17163116.1A patent/EP3239304B1/en active Active
- 2007-04-04 PL PL15158621T patent/PL2963127T3/pl unknown
- 2007-04-04 JP JP2009504137A patent/JP5389638B2/ja active Active
- 2007-04-04 DK DK17163116.1T patent/DK3239304T3/da active
- 2007-04-04 ES ES17163116T patent/ES2829295T3/es active Active
- 2007-04-04 DK DK07747276.9T patent/DK2002017T3/da active
- 2007-04-04 ES ES15158621.1T patent/ES2645661T3/es active Active
- 2007-04-04 WO PCT/NL2007/000094 patent/WO2007114693A2/en active Application Filing
- 2007-04-04 EP EP15158621.1A patent/EP2963127B1/en active Active
- 2007-04-04 US US12/296,009 patent/US20090253581A1/en not_active Abandoned
- 2007-04-04 PT PT151586211T patent/PT2963127T/pt unknown
- 2007-04-04 ES ES07747276.9T patent/ES2545264T3/es active Active
-
2012
- 2012-02-02 US US13/364,799 patent/US20120135871A1/en not_active Abandoned
- 2012-04-18 US US13/449,629 patent/US20120202698A1/en not_active Abandoned
-
2013
- 2013-07-29 JP JP2013156870A patent/JP2013215212A/ja not_active Withdrawn
-
2014
- 2014-05-22 US US14/285,430 patent/US10023907B2/en active Active
-
2016
- 2016-07-01 HK HK16107675.9A patent/HK1219761A1/zh unknown
-
2018
- 2018-03-16 HK HK18103703.2A patent/HK1244301A1/zh unknown
- 2018-06-05 US US16/000,252 patent/US20180291439A1/en not_active Abandoned
-
2019
- 2019-07-19 US US16/516,866 patent/US20200181694A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20200181694A1 (en) | 2020-06-11 |
JP2013215212A (ja) | 2013-10-24 |
JP2009536817A (ja) | 2009-10-22 |
EP3239304A1 (en) | 2017-11-01 |
US20120135871A1 (en) | 2012-05-31 |
ES2545264T3 (es) | 2015-09-09 |
US20120202698A1 (en) | 2012-08-09 |
US10023907B2 (en) | 2018-07-17 |
US20090253581A1 (en) | 2009-10-08 |
ES2645661T3 (es) | 2017-12-07 |
WO2007114693A3 (en) | 2007-12-21 |
WO2007114693A2 (en) | 2007-10-11 |
PT2963127T (pt) | 2017-10-06 |
EP2963127B1 (en) | 2017-08-16 |
US20180291439A1 (en) | 2018-10-11 |
EP3239304B1 (en) | 2020-08-19 |
EP2002017A2 (en) | 2008-12-17 |
HK1244301A1 (zh) | 2018-08-03 |
US20140303007A1 (en) | 2014-10-09 |
EP2002017B1 (en) | 2015-06-10 |
DK2002017T3 (da) | 2015-09-07 |
ES2829295T3 (es) | 2021-05-31 |
HK1219761A1 (zh) | 2017-04-13 |
PL2963127T3 (pl) | 2018-01-31 |
JP5389638B2 (ja) | 2014-01-15 |
EP2963127A1 (en) | 2016-01-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK3239304T3 (da) | Højgennemløbsdetektering af molekylære markører baseret på AFLP og sekventering med højt gennemløb | |
DK1991273T4 (da) | Mærkning og påvisning af post-translationelt modificerede proteiner | |
DK2084444T4 (da) | Testning og udluftning af rør-annulus | |
DK1966393T3 (da) | Fremgangsmåde til AFLP-baseret påvisning af polymorfisme med høj omsætning | |
DK2263217T3 (da) | Fremgangsmåde og system til detektering af begivenheder | |
DK1919904T3 (da) | Makrocykliske inhibitorer af hepatitis-c-virus | |
DK2155228T3 (da) | Polypeptidinhibitorer af HSP27-kinase og anvendelser herfor | |
DK2158726T3 (da) | Fremgangsmåde og system til bestemmelse af fysisk placering af udstyr | |
BRPI0818522A2 (pt) | filtragem com base em localização e tempo de informações de difusão. | |
DK3851196T3 (da) | Fremgangsmåde og indretning til manipulation og/eller detektering af partikler | |
FI20075124A0 (fi) | Menetelmä ja testikitti nukleotidivariaatioiden toteamiseksi | |
DK1918385T3 (da) | Fremgangsmåde til detektion af mikroorganisme og kit til detektion af mikroorganisme | |
DE602007008174D1 (de) | Verfahren und System zur Erkennung von Phishing | |
DK2402758T3 (da) | Fremgangsmåder og anvendelser til identificering af oprindelsen af et karcinom med ukendt primær oprindelse | |
DK1912636T3 (da) | N-(arylamino)-sulfonamid-inhibitorer af mek | |
DK2120579T3 (da) | Inhibitorer af poly(ADP-ripose)polymerase | |
DK2081955T3 (da) | Metastinderivater og anvendelse deraf | |
DK2021788T3 (da) | Detektering af åbne revner i æg | |
DK1972223T3 (da) | Skridsikker trædeflade og fremgangsmåde til fremstilling af en sådan trædeflade | |
BRPI0819455A2 (pt) | Sistema e método de sincronização de tempo | |
DK2189537T3 (da) | Detektion og behandling af skizofreni | |
SE0600870L (sv) | Detekteringsanordning och förfarande | |
DK3263589T5 (da) | Peptidsekvenser og sammensætninger | |
DK2099935T3 (da) | Array for detektion af mikrober | |
DK3150721T3 (da) | Pankreascancermarkører og detekteringsfremgangsmåder |