DK3192796T3 - Aldosereduktaseinhibitorer og anvendelser deraf - Google Patents

Aldosereduktaseinhibitorer og anvendelser deraf Download PDF

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Publication number
DK3192796T3
DK3192796T3 DK16187936T DK16187936T DK3192796T3 DK 3192796 T3 DK3192796 T3 DK 3192796T3 DK 16187936 T DK16187936 T DK 16187936T DK 16187936 T DK16187936 T DK 16187936T DK 3192796 T3 DK3192796 T3 DK 3192796T3
Authority
DK
Denmark
Prior art keywords
reductase inhibitors
aldose reductase
aldose
inhibitors
reductase
Prior art date
Application number
DK16187936T
Other languages
English (en)
Inventor
Andrew Wasmuth
Donald W Landry
Shi Xian Deng
Ravichandran Ramasamy
Ann Marie Schmidt
Banavara L Mylari
Original Assignee
Univ Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Columbia filed Critical Univ Columbia
Application granted granted Critical
Publication of DK3192796T3 publication Critical patent/DK3192796T3/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK16187936T 2010-07-16 2011-07-14 Aldosereduktaseinhibitorer og anvendelser deraf DK3192796T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36509810P 2010-07-16 2010-07-16
EP11807523.3A EP2593456B1 (en) 2010-07-16 2011-07-14 Aldose reductase inhibitors and uses thereof

Publications (1)

Publication Number Publication Date
DK3192796T3 true DK3192796T3 (da) 2019-12-09

Family

ID=45469805

Family Applications (3)

Application Number Title Priority Date Filing Date
DK16187936T DK3192796T3 (da) 2010-07-16 2011-07-14 Aldosereduktaseinhibitorer og anvendelser deraf
DK19194956.9T DK3597650T3 (da) 2010-07-16 2011-07-14 Aldosereduktasehæmmere og anvendelser deraf
DK11807523.3T DK2593456T3 (da) 2010-07-16 2011-07-14 Aldosereduktaseinhibitorer og anvendelser deraf

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK19194956.9T DK3597650T3 (da) 2010-07-16 2011-07-14 Aldosereduktasehæmmere og anvendelser deraf
DK11807523.3T DK2593456T3 (da) 2010-07-16 2011-07-14 Aldosereduktaseinhibitorer og anvendelser deraf

Country Status (16)

Country Link
EP (4) EP3192796B1 (da)
JP (4) JP5934206B2 (da)
CN (2) CN105732640B (da)
AU (1) AU2011279058B2 (da)
CA (1) CA2804640C (da)
DK (3) DK3192796T3 (da)
ES (3) ES2613700T3 (da)
HK (1) HK1223925A1 (da)
HR (1) HRP20221430T1 (da)
HU (3) HUE060473T2 (da)
LT (1) LT3597650T (da)
PL (3) PL3192796T3 (da)
PT (1) PT3597650T (da)
RS (1) RS63796B1 (da)
SI (1) SI3597650T1 (da)
WO (1) WO2012009553A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8916563B2 (en) 2010-07-16 2014-12-23 The Trustees Of Columbia University In The City Of New York Aldose reductase inhibitors and uses thereof
EP3192796B1 (en) * 2010-07-16 2019-09-04 The Trustees of Columbia University in the City of New York Aldose reductase inhibitors and uses thereof
WO2014126885A1 (en) * 2013-02-13 2014-08-21 Mylari Banavara L Water soluble salts of aldose reductase inhibitors for treatment of diabetic complications
SI3352754T1 (sl) * 2016-06-21 2021-03-31 The Trustees Of Columbia University In The City Of New York Zaviralci aldozne reduktaze in postopki njihove uporabe
CA3071114A1 (en) 2017-07-28 2019-01-31 Applied Therapeutics Inc. Compositions and methods for treating galactosemia
CN108101883B (zh) * 2018-01-31 2018-11-13 佳木斯大学附属第一医院 一种用于防治糖尿病视网膜病变的药物及其制备方法
EP3924060A4 (en) * 2019-02-12 2023-03-22 Applied Therapeutics, Inc. METHODS FOR TREATMENT OF SKIN AGING
JP7457033B2 (ja) * 2019-02-28 2024-03-27 石薬集団中奇制薬技術(石家庄)有限公司 アルドース還元酵素阻害剤の塩、及びその製造方法と使用
JP2022519944A (ja) * 2019-04-01 2022-03-25 アプライド セラピューティクス インコーポレイテッド アルドースレダクターゼの阻害剤
JP2023524504A (ja) 2020-05-01 2023-06-12 アプライド セラピューティクス, インコーポレイテッド ソルビトールデヒドロゲナーゼ欠乏症を処置するためのアルドースレダクターゼ阻害剤
US20230322786A1 (en) * 2020-09-08 2023-10-12 Teva Pharmaceuticals International Gmbh Solid state forms of at-001 and process for preparation thereof

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5304A (en) 1847-09-25 Improvement in preparing and hardening raw hides
US557A (en) 1838-01-09 James macgregor
CA1299178C (en) * 1985-11-07 1992-04-21 Banavara Lakshmana Mylari Heterocyclic oxophtalazinyl acetic acids
ES2032749T3 (es) * 1985-11-07 1993-03-01 Pfizer Inc. Acidos oxoftalazinil-aceticos heterociclicos.
US4939140A (en) 1985-11-07 1990-07-03 Pfizer Inc. Heterocyclic oxophthalazinyl acetic acids
WO1989006651A1 (en) * 1988-01-19 1989-07-27 Pfizer Inc. 1h-indazole-3-acetic acids as aldose reductase inhibitors
US4996204A (en) * 1989-05-11 1991-02-26 Pfizer Inc. Pyrido[2,3-d]pyridazinones as aldose reductase inhibitors
US4954629A (en) * 1989-05-11 1990-09-04 Pfizer Inc. Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof
FR2647676A1 (fr) * 1989-06-05 1990-12-07 Union Pharma Scient Appl Nouveaux derives de pyridazinone, leurs procedes de preparation, medicaments les contenant, utiles notamment comme inhibiteurs de l'aldose reductase
US5304557A (en) * 1989-12-15 1994-04-19 Pfizer Inc. Substituted oxoophthalazinyl acetic acids and analogs thereof
JPH0495025A (ja) 1990-08-08 1992-03-27 Asahi Chem Ind Co Ltd アルドースリダクターゼ阻害剤
WO1997008126A1 (en) 1995-08-28 1997-03-06 American Home Products Corporation Phenoxy acetic acids as aldose reductase inhibitors and antihyperglycemic agents
YU59600A (sh) * 1998-03-31 2002-12-10 The Institute For Pharmaceutical Discovery Inc. Supstituisane indolalkanoidske kiseline
EP0982306A3 (en) 1998-08-21 2000-07-05 Pfizer Products Inc. Polymorph of zopolrestat monohydrate
US6570013B2 (en) 2000-02-16 2003-05-27 Pfizer Inc Salts of zopolrestat
WO2003061660A1 (en) 2002-01-23 2003-07-31 Eli Lilly And Company Melanocortin receptor agonists
EP3192796B1 (en) * 2010-07-16 2019-09-04 The Trustees of Columbia University in the City of New York Aldose reductase inhibitors and uses thereof

Also Published As

Publication number Publication date
PL3597650T3 (pl) 2023-02-06
ES2613700T3 (es) 2017-05-25
CN103052637B (zh) 2016-03-23
HUE031506T2 (en) 2017-07-28
CA2804640A1 (en) 2012-01-19
PL2593456T3 (pl) 2017-06-30
SI3597650T1 (sl) 2023-02-28
HUE047346T2 (hu) 2020-04-28
PL3192796T3 (pl) 2020-06-15
EP3192796B1 (en) 2019-09-04
JP6306251B2 (ja) 2018-04-04
EP4124620A1 (en) 2023-02-01
AU2011279058B2 (en) 2015-10-01
HUE060473T2 (hu) 2023-03-28
JP5934206B2 (ja) 2016-06-15
EP3597650A1 (en) 2020-01-22
DK2593456T3 (da) 2017-02-06
CN105732640B (zh) 2019-01-08
EP2593456A4 (en) 2013-10-30
WO2012009553A1 (en) 2012-01-19
PT3597650T (pt) 2022-12-16
ES2931319T3 (es) 2022-12-28
JP6165897B2 (ja) 2017-07-19
EP3192796A1 (en) 2017-07-19
CN105732640A (zh) 2016-07-06
AU2011279058A1 (en) 2013-01-24
RS63796B1 (sr) 2022-12-30
DK3597650T3 (da) 2022-11-21
JP6430670B2 (ja) 2018-11-28
CN103052637A (zh) 2013-04-17
JP2013531062A (ja) 2013-08-01
EP3597650B1 (en) 2022-09-07
CA2804640C (en) 2018-09-25
LT3597650T (lt) 2022-12-12
JP2017200937A (ja) 2017-11-09
ES2769950T3 (es) 2020-06-29
JP2018087253A (ja) 2018-06-07
HK1223925A1 (zh) 2017-08-11
HRP20221430T1 (hr) 2023-01-06
EP2593456B1 (en) 2016-11-30
EP2593456A1 (en) 2013-05-22
JP2016106107A (ja) 2016-06-16

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