HUE060473T2 - Aldóz-reduktáz inhibitorok és felhasználásuk - Google Patents

Aldóz-reduktáz inhibitorok és felhasználásuk

Info

Publication number
HUE060473T2
HUE060473T2 HUE19194956A HUE19194956A HUE060473T2 HU E060473 T2 HUE060473 T2 HU E060473T2 HU E19194956 A HUE19194956 A HU E19194956A HU E19194956 A HUE19194956 A HU E19194956A HU E060473 T2 HUE060473 T2 HU E060473T2
Authority
HU
Hungary
Prior art keywords
reductase inhibitors
aldose reductase
aldose
inhibitors
reductase
Prior art date
Application number
HUE19194956A
Other languages
English (en)
Inventor
Andrew Wasmuth
Donald W Landry
Shi Deng
Ravichandran Ramasamy
Ann Marie Schmidt
Banavara MYLARI
Original Assignee
Univ Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Columbia filed Critical Univ Columbia
Publication of HUE060473T2 publication Critical patent/HUE060473T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
HUE19194956A 2010-07-16 2011-07-14 Aldóz-reduktáz inhibitorok és felhasználásuk HUE060473T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36509810P 2010-07-16 2010-07-16

Publications (1)

Publication Number Publication Date
HUE060473T2 true HUE060473T2 (hu) 2023-03-28

Family

ID=45469805

Family Applications (3)

Application Number Title Priority Date Filing Date
HUE19194956A HUE060473T2 (hu) 2010-07-16 2011-07-14 Aldóz-reduktáz inhibitorok és felhasználásuk
HUE16187936A HUE047346T2 (hu) 2010-07-16 2011-07-14 Aldóz reduktáz inhibitorok és alkalmazásuk
HUE11807523A HUE031506T2 (hu) 2010-07-16 2011-07-14 Aldóz reduktáz inhibitorok és alkalmazásuk

Family Applications After (2)

Application Number Title Priority Date Filing Date
HUE16187936A HUE047346T2 (hu) 2010-07-16 2011-07-14 Aldóz reduktáz inhibitorok és alkalmazásuk
HUE11807523A HUE031506T2 (hu) 2010-07-16 2011-07-14 Aldóz reduktáz inhibitorok és alkalmazásuk

Country Status (16)

Country Link
EP (4) EP3192796B1 (hu)
JP (4) JP5934206B2 (hu)
CN (2) CN105732640B (hu)
AU (1) AU2011279058B2 (hu)
CA (1) CA2804640C (hu)
DK (3) DK3597650T3 (hu)
ES (3) ES2613700T3 (hu)
HK (1) HK1223925A1 (hu)
HR (1) HRP20221430T1 (hu)
HU (3) HUE060473T2 (hu)
LT (1) LT3597650T (hu)
PL (3) PL3597650T3 (hu)
PT (1) PT3597650T (hu)
RS (1) RS63796B1 (hu)
SI (1) SI3597650T1 (hu)
WO (1) WO2012009553A1 (hu)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5934206B2 (ja) * 2010-07-16 2016-06-15 ザ・トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク アルドース還元酵素阻害剤および同使用方法
US8916563B2 (en) 2010-07-16 2014-12-23 The Trustees Of Columbia University In The City Of New York Aldose reductase inhibitors and uses thereof
US20140228319A1 (en) * 2013-02-13 2014-08-14 Banavara L. Mylari Water soluble salts of aldose reductase inhibitors for treatment of diabetic complications
ES2836500T3 (es) 2016-06-21 2021-06-25 Univ Columbia Inhibidores de aldosa reductasa y métodos de uso de los mismos
US11590131B2 (en) 2017-07-28 2023-02-28 Applied Therapeutics, Inc. Compositions and methods for treating galactosemia
CN108101883B (zh) * 2018-01-31 2018-11-13 佳木斯大学附属第一医院 一种用于防治糖尿病视网膜病变的药物及其制备方法
WO2020167937A1 (en) * 2019-02-12 2020-08-20 Applied Therapeutics, Inc. Methods for treating cutaneous aging
WO2020173495A1 (zh) * 2019-02-28 2020-09-03 石药集团中奇制药技术(石家庄)有限公司 醛糖还原酶抑制剂的盐及其制备方法和应用
SG11202110590PA (en) * 2019-04-01 2021-10-28 Applied Therapeutics Inc Inhibitors of aldose reductase
CN115996725A (zh) 2020-05-01 2023-04-21 应用治疗公司 用于治疗山梨糖醇脱氢酶缺乏症的醛糖还原酶抑制剂
WO2022055836A1 (en) * 2020-09-08 2022-03-17 Teva Pharmaceuticals International Gmbh Solid state forms of at-001 and process for preparation thereof

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US557A (en) 1838-01-09 James macgregor
US5304A (en) 1847-09-25 Improvement in preparing and hardening raw hides
EP0222576B1 (en) * 1985-11-07 1992-03-18 Pfizer Inc. Heterocyclic oxophthalazinyl acetic acids
CA1299178C (en) * 1985-11-07 1992-04-21 Banavara Lakshmana Mylari Heterocyclic oxophtalazinyl acetic acids
US4939140A (en) 1985-11-07 1990-07-03 Pfizer Inc. Heterocyclic oxophthalazinyl acetic acids
WO1989006651A1 (en) * 1988-01-19 1989-07-27 Pfizer Inc. 1h-indazole-3-acetic acids as aldose reductase inhibitors
US4954629A (en) * 1989-05-11 1990-09-04 Pfizer Inc. Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof
US4996204A (en) * 1989-05-11 1991-02-26 Pfizer Inc. Pyrido[2,3-d]pyridazinones as aldose reductase inhibitors
FR2647676A1 (fr) * 1989-06-05 1990-12-07 Union Pharma Scient Appl Nouveaux derives de pyridazinone, leurs procedes de preparation, medicaments les contenant, utiles notamment comme inhibiteurs de l'aldose reductase
WO1991009019A1 (en) 1989-12-15 1991-06-27 Pfizer Inc. Substituted oxophthalazinyl acetic acids and analogs thereof
JPH0495025A (ja) 1990-08-08 1992-03-27 Asahi Chem Ind Co Ltd アルドースリダクターゼ阻害剤
WO1997008126A1 (en) 1995-08-28 1997-03-06 American Home Products Corporation Phenoxy acetic acids as aldose reductase inhibitors and antihyperglycemic agents
CN1205207C (zh) * 1998-03-31 2005-06-08 药品发现学会公司 取代的吲哚链烷酸
EP0982306A3 (en) 1998-08-21 2000-07-05 Pfizer Products Inc. Polymorph of zopolrestat monohydrate
US6570013B2 (en) 2000-02-16 2003-05-27 Pfizer Inc Salts of zopolrestat
ES2274201T3 (es) 2002-01-23 2007-05-16 Eli Lilly And Company Agonistas del receptor de melanocortina.
JP5934206B2 (ja) * 2010-07-16 2016-06-15 ザ・トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク アルドース還元酵素阻害剤および同使用方法

Also Published As

Publication number Publication date
HRP20221430T1 (hr) 2023-01-06
ES2613700T3 (es) 2017-05-25
DK3597650T3 (da) 2022-11-21
ES2931319T3 (es) 2022-12-28
SI3597650T1 (sl) 2023-02-28
EP2593456A1 (en) 2013-05-22
RS63796B1 (sr) 2022-12-30
CN103052637A (zh) 2013-04-17
EP3597650B1 (en) 2022-09-07
EP2593456A4 (en) 2013-10-30
HUE031506T2 (hu) 2017-07-28
EP2593456B1 (en) 2016-11-30
PL3597650T3 (pl) 2023-02-06
PL2593456T3 (pl) 2017-06-30
ES2769950T3 (es) 2020-06-29
EP3597650A1 (en) 2020-01-22
CA2804640C (en) 2018-09-25
JP2013531062A (ja) 2013-08-01
JP6165897B2 (ja) 2017-07-19
JP6306251B2 (ja) 2018-04-04
DK2593456T3 (en) 2017-02-06
EP3192796B1 (en) 2019-09-04
JP6430670B2 (ja) 2018-11-28
DK3192796T3 (da) 2019-12-09
AU2011279058B2 (en) 2015-10-01
EP4124620A1 (en) 2023-02-01
JP2018087253A (ja) 2018-06-07
CN103052637B (zh) 2016-03-23
CN105732640A (zh) 2016-07-06
PL3192796T3 (pl) 2020-06-15
AU2011279058A1 (en) 2013-01-24
CA2804640A1 (en) 2012-01-19
JP5934206B2 (ja) 2016-06-15
PT3597650T (pt) 2022-12-16
HUE047346T2 (hu) 2020-04-28
CN105732640B (zh) 2019-01-08
EP3192796A1 (en) 2017-07-19
JP2016106107A (ja) 2016-06-16
HK1223925A1 (zh) 2017-08-11
WO2012009553A1 (en) 2012-01-19
LT3597650T (lt) 2022-12-12
JP2017200937A (ja) 2017-11-09

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