LT3597650T - Aldozės reduktazės inhibitoriai, ir jų naudojimas - Google Patents

Aldozės reduktazės inhibitoriai, ir jų naudojimas

Info

Publication number
LT3597650T
LT3597650T LTEP19194956.9T LT19194956T LT3597650T LT 3597650 T LT3597650 T LT 3597650T LT 19194956 T LT19194956 T LT 19194956T LT 3597650 T LT3597650 T LT 3597650T
Authority
LT
Lithuania
Prior art keywords
reductase inhibitors
aldose reductase
aldose
inhibitors
reductase
Prior art date
Application number
LTEP19194956.9T
Other languages
English (en)
Inventor
Andrew Wasmuth
Donald W. Landry
Shi Deng
Ravichandran Ramasamy
Ann Marie Schmidt
Banavara MYLARI
Original Assignee
The Trustees Of Columbia University In The City Of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Trustees Of Columbia University In The City Of New York filed Critical The Trustees Of Columbia University In The City Of New York
Publication of LT3597650T publication Critical patent/LT3597650T/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
LTEP19194956.9T 2010-07-16 2011-07-14 Aldozės reduktazės inhibitoriai, ir jų naudojimas LT3597650T (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US36509810P 2010-07-16 2010-07-16

Publications (1)

Publication Number Publication Date
LT3597650T true LT3597650T (lt) 2022-12-12

Family

ID=45469805

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP19194956.9T LT3597650T (lt) 2010-07-16 2011-07-14 Aldozės reduktazės inhibitoriai, ir jų naudojimas

Country Status (16)

Country Link
EP (4) EP4124620A1 (lt)
JP (4) JP5934206B2 (lt)
CN (2) CN105732640B (lt)
AU (1) AU2011279058B2 (lt)
CA (1) CA2804640C (lt)
DK (3) DK2593456T3 (lt)
ES (3) ES2613700T3 (lt)
HK (1) HK1223925A1 (lt)
HR (1) HRP20221430T1 (lt)
HU (3) HUE031506T2 (lt)
LT (1) LT3597650T (lt)
PL (3) PL2593456T3 (lt)
PT (1) PT3597650T (lt)
RS (1) RS63796B1 (lt)
SI (1) SI3597650T1 (lt)
WO (1) WO2012009553A1 (lt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8916563B2 (en) 2010-07-16 2014-12-23 The Trustees Of Columbia University In The City Of New York Aldose reductase inhibitors and uses thereof
EP4124620A1 (en) * 2010-07-16 2023-02-01 The Trustees of Columbia University in the City of New York Aldose reductase inhibitors and uses thereof
US20140228319A1 (en) * 2013-02-13 2014-08-14 Banavara L. Mylari Water soluble salts of aldose reductase inhibitors for treatment of diabetic complications
PT3352754T (pt) 2016-06-21 2020-12-07 Univ Columbia Inibidores da aldose redutase e métodos de seu uso
EP3658142B1 (en) 2017-07-28 2024-04-17 Applied Therapeutics, Inc. Compositions and methods for treating galactosemia
CN108101883B (zh) * 2018-01-31 2018-11-13 佳木斯大学附属第一医院 一种用于防治糖尿病视网膜病变的药物及其制备方法
EP3924060A4 (en) * 2019-02-12 2023-03-22 Applied Therapeutics, Inc. METHODS FOR TREATMENT OF SKIN AGING
AU2020229932B2 (en) * 2019-02-28 2023-09-21 Cspc Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd. Salt of aldose reductase inhibitor, and preparation method and application thereof
EP3947391A1 (en) * 2019-04-01 2022-02-09 Applied Therapeutics Inc. Inhibitors of aldose reductase
EP3966320A4 (en) 2019-05-07 2023-10-25 University of Miami TREATMENT AND DETECTION OF HEREDITARY NEUROPATHIES AND ASSOCIATED DISORDERS
KR20230005944A (ko) 2020-05-01 2023-01-10 어플라이드 테라퓨틱스 인크. 소르비톨 데히드로게나제 결핍 치료를 위한 알도스 리덕타제 억제제
EP4211136A1 (en) * 2020-09-08 2023-07-19 Teva Pharmaceuticals International GmbH Solid state forms of at-001 and process for preparation thereof

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US557A (en) 1838-01-09 James macgregor
US5304A (en) 1847-09-25 Improvement in preparing and hardening raw hides
CA1299178C (en) * 1985-11-07 1992-04-21 Banavara Lakshmana Mylari Heterocyclic oxophtalazinyl acetic acids
US4939140A (en) 1985-11-07 1990-07-03 Pfizer Inc. Heterocyclic oxophthalazinyl acetic acids
IL80475A (en) * 1985-11-07 1993-01-31 Pfizer Heterocyclic-substituted 4-oxo (or thio)-3h- phthalazinyl-acetic acid derivatives and pharmaceutical compositions containing them
WO1989006651A1 (en) * 1988-01-19 1989-07-27 Pfizer Inc. 1h-indazole-3-acetic acids as aldose reductase inhibitors
US4954629A (en) 1989-05-11 1990-09-04 Pfizer Inc. Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof
US4996204A (en) * 1989-05-11 1991-02-26 Pfizer Inc. Pyrido[2,3-d]pyridazinones as aldose reductase inhibitors
FR2647676A1 (fr) * 1989-06-05 1990-12-07 Union Pharma Scient Appl Nouveaux derives de pyridazinone, leurs procedes de preparation, medicaments les contenant, utiles notamment comme inhibiteurs de l'aldose reductase
US5304557A (en) 1989-12-15 1994-04-19 Pfizer Inc. Substituted oxoophthalazinyl acetic acids and analogs thereof
JPH0495025A (ja) 1990-08-08 1992-03-27 Asahi Chem Ind Co Ltd アルドースリダクターゼ阻害剤
WO1997008126A1 (en) 1995-08-28 1997-03-06 American Home Products Corporation Phenoxy acetic acids as aldose reductase inhibitors and antihyperglycemic agents
OA11622A (en) * 1998-03-31 2004-09-16 Inst For Pharm Discovery Inc Substituted indolealkanoic acids.
EP0982306A3 (en) 1998-08-21 2000-07-05 Pfizer Products Inc. Polymorph of zopolrestat monohydrate
US6570013B2 (en) 2000-02-16 2003-05-27 Pfizer Inc Salts of zopolrestat
EP1469851B1 (en) 2002-01-23 2006-10-11 Eli Lilly And Company Melanocortin receptor agonists
EP4124620A1 (en) * 2010-07-16 2023-02-01 The Trustees of Columbia University in the City of New York Aldose reductase inhibitors and uses thereof

Also Published As

Publication number Publication date
HRP20221430T1 (hr) 2023-01-06
EP3597650A1 (en) 2020-01-22
PL2593456T3 (pl) 2017-06-30
CN103052637B (zh) 2016-03-23
HUE031506T2 (en) 2017-07-28
JP2016106107A (ja) 2016-06-16
JP5934206B2 (ja) 2016-06-15
JP2013531062A (ja) 2013-08-01
CA2804640C (en) 2018-09-25
HUE060473T2 (hu) 2023-03-28
JP6165897B2 (ja) 2017-07-19
EP4124620A1 (en) 2023-02-01
JP6430670B2 (ja) 2018-11-28
CA2804640A1 (en) 2012-01-19
SI3597650T1 (sl) 2023-02-28
RS63796B1 (sr) 2022-12-30
EP2593456B1 (en) 2016-11-30
AU2011279058B2 (en) 2015-10-01
EP3597650B1 (en) 2022-09-07
PL3597650T3 (pl) 2023-02-06
CN105732640B (zh) 2019-01-08
PT3597650T (pt) 2022-12-16
DK3192796T3 (da) 2019-12-09
PL3192796T3 (pl) 2020-06-15
JP2018087253A (ja) 2018-06-07
EP2593456A1 (en) 2013-05-22
ES2769950T3 (es) 2020-06-29
DK2593456T3 (en) 2017-02-06
WO2012009553A1 (en) 2012-01-19
ES2931319T3 (es) 2022-12-28
DK3597650T3 (da) 2022-11-21
EP2593456A4 (en) 2013-10-30
CN105732640A (zh) 2016-07-06
CN103052637A (zh) 2013-04-17
JP2017200937A (ja) 2017-11-09
HUE047346T2 (hu) 2020-04-28
JP6306251B2 (ja) 2018-04-04
EP3192796B1 (en) 2019-09-04
EP3192796A1 (en) 2017-07-19
HK1223925A1 (zh) 2017-08-11
AU2011279058A1 (en) 2013-01-24
ES2613700T3 (es) 2017-05-25

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