PT3597650T - Inibidores da aldose redutase e utilizações dos mesmos - Google Patents
Inibidores da aldose redutase e utilizações dos mesmosInfo
- Publication number
- PT3597650T PT3597650T PT191949569T PT19194956T PT3597650T PT 3597650 T PT3597650 T PT 3597650T PT 191949569 T PT191949569 T PT 191949569T PT 19194956 T PT19194956 T PT 19194956T PT 3597650 T PT3597650 T PT 3597650T
- Authority
- PT
- Portugal
- Prior art keywords
- reductase inhibitors
- aldose reductase
- aldose
- inhibitors
- reductase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Cosmetics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36509810P | 2010-07-16 | 2010-07-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT3597650T true PT3597650T (pt) | 2022-12-16 |
Family
ID=45469805
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT191949569T PT3597650T (pt) | 2010-07-16 | 2011-07-14 | Inibidores da aldose redutase e utilizações dos mesmos |
Country Status (16)
| Country | Link |
|---|---|
| EP (4) | EP2593456B1 (pt) |
| JP (4) | JP5934206B2 (pt) |
| CN (2) | CN105732640B (pt) |
| AU (1) | AU2011279058B2 (pt) |
| CA (1) | CA2804640C (pt) |
| DK (3) | DK3597650T3 (pt) |
| ES (3) | ES2931319T3 (pt) |
| HK (1) | HK1223925A1 (pt) |
| HR (1) | HRP20221430T1 (pt) |
| HU (3) | HUE047346T2 (pt) |
| LT (1) | LT3597650T (pt) |
| PL (3) | PL2593456T3 (pt) |
| PT (1) | PT3597650T (pt) |
| RS (1) | RS63796B1 (pt) |
| SI (1) | SI3597650T1 (pt) |
| WO (1) | WO2012009553A1 (pt) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK3597650T3 (da) * | 2010-07-16 | 2022-11-21 | Univ Columbia | Aldosereduktasehæmmere og anvendelser deraf |
| US8916563B2 (en) | 2010-07-16 | 2014-12-23 | The Trustees Of Columbia University In The City Of New York | Aldose reductase inhibitors and uses thereof |
| WO2014126885A1 (en) * | 2013-02-13 | 2014-08-21 | Mylari Banavara L | Water soluble salts of aldose reductase inhibitors for treatment of diabetic complications |
| EP4316603A3 (en) * | 2016-06-21 | 2024-04-17 | The Trustees of Columbia University in the City of New York | 4-oxo-3,4-dihydrothieno[3,4-d]pyridazine compounds as aldose reductase inhibitors and methods of use thereof |
| EP4417260A2 (en) | 2017-07-28 | 2024-08-21 | Applied Therapeutics, Inc. | Compositions and methods for treating galactosemia |
| CN108101883B (zh) * | 2018-01-31 | 2018-11-13 | 佳木斯大学附属第一医院 | 一种用于防治糖尿病视网膜病变的药物及其制备方法 |
| WO2020167937A1 (en) * | 2019-02-12 | 2020-08-20 | Applied Therapeutics, Inc. | Methods for treating cutaneous aging |
| JP7457033B2 (ja) * | 2019-02-28 | 2024-03-27 | 石薬集団中奇制薬技術（石家庄）有限公司 | アルドース還元酵素阻害剤の塩、及びその製造方法と使用 |
| KR20220003529A (ko) | 2019-04-01 | 2022-01-10 | 어플라이드 테라퓨틱스 인크. | 알도스 리덕타제의 억제제 |
| AU2020268368A1 (en) | 2019-05-07 | 2022-01-06 | Ucl Business Ltd | Treatment and detection of inherited neuropathies and associated disorders |
| AU2021264454A1 (en) | 2020-05-01 | 2022-12-08 | Applied Therapeutics, Inc. | Aldose reductase inhibitors for treating sorbitol dehydrogenase deficiency |
| WO2022055836A1 (en) | 2020-09-08 | 2022-03-17 | Teva Pharmaceuticals International Gmbh | Solid state forms of at-001 and process for preparation thereof |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US557A (en) | 1838-01-09 | James macgregor | ||
| US5304A (en) | 1847-09-25 | Improvement in preparing and hardening raw hides | ||
| CA1299178C (en) * | 1985-11-07 | 1992-04-21 | Banavara Lakshmana Mylari | Heterocyclic oxophtalazinyl acetic acids |
| US4939140A (en) | 1985-11-07 | 1990-07-03 | Pfizer Inc. | Heterocyclic oxophthalazinyl acetic acids |
| DE3684410D1 (de) * | 1985-11-07 | 1992-04-23 | Pfizer | Heterocyclische oxophthalazinylessigsaeure. |
| WO1989006651A1 (en) * | 1988-01-19 | 1989-07-27 | Pfizer Inc. | 1h-indazole-3-acetic acids as aldose reductase inhibitors |
| US4954629A (en) * | 1989-05-11 | 1990-09-04 | Pfizer Inc. | Process and intermediates for the preparation of oxophthalazinyl acetic acids and analogs thereof |
| US4996204A (en) * | 1989-05-11 | 1991-02-26 | Pfizer Inc. | Pyrido[2,3-d]pyridazinones as aldose reductase inhibitors |
| FR2647676A1 (fr) * | 1989-06-05 | 1990-12-07 | Union Pharma Scient Appl | Nouveaux derives de pyridazinone, leurs procedes de preparation, medicaments les contenant, utiles notamment comme inhibiteurs de l'aldose reductase |
| WO1991009019A1 (en) * | 1989-12-15 | 1991-06-27 | Pfizer Inc. | Substituted oxophthalazinyl acetic acids and analogs thereof |
| JPH0495025A (ja) | 1990-08-08 | 1992-03-27 | Asahi Chem Ind Co Ltd | アルドースリダクターゼ阻害剤 |
| EP0847379A1 (en) | 1995-08-28 | 1998-06-17 | American Home Products Corporation | Phenoxy acetic acids as aldose reductase inhibitors and antihyperglycemic agents |
| KR100584650B1 (ko) * | 1998-03-31 | 2006-05-30 | 디 인스티튜트스 포 파마슈티컬 디스커버리, 엘엘씨 | 치환된 인돌알칸산 |
| EP0982306A3 (en) | 1998-08-21 | 2000-07-05 | Pfizer Products Inc. | Polymorph of zopolrestat monohydrate |
| US6570013B2 (en) | 2000-02-16 | 2003-05-27 | Pfizer Inc | Salts of zopolrestat |
| ES2274201T3 (es) | 2002-01-23 | 2007-05-16 | Eli Lilly And Company | Agonistas del receptor de melanocortina. |
| DK3597650T3 (da) * | 2010-07-16 | 2022-11-21 | Univ Columbia | Aldosereduktasehæmmere og anvendelser deraf |
-
2011
- 2011-07-14 DK DK19194956.9T patent/DK3597650T3/da active
- 2011-07-14 EP EP11807523.3A patent/EP2593456B1/en active Active
- 2011-07-14 DK DK16187936T patent/DK3192796T3/da active
- 2011-07-14 HU HUE16187936A patent/HUE047346T2/hu unknown
- 2011-07-14 RS RS20221062A patent/RS63796B1/sr unknown
- 2011-07-14 WO PCT/US2011/044038 patent/WO2012009553A1/en active Application Filing
- 2011-07-14 CN CN201610124090.4A patent/CN105732640B/zh active Active
- 2011-07-14 LT LTEP19194956.9T patent/LT3597650T/lt unknown
- 2011-07-14 PL PL11807523T patent/PL2593456T3/pl unknown
- 2011-07-14 EP EP16187936.6A patent/EP3192796B1/en active Active
- 2011-07-14 EP EP22183971.5A patent/EP4124620A1/en active Pending
- 2011-07-14 PL PL19194956.9T patent/PL3597650T3/pl unknown
- 2011-07-14 CN CN201180034944.5A patent/CN103052637B/zh active Active
- 2011-07-14 SI SI201132072T patent/SI3597650T1/sl unknown
- 2011-07-14 ES ES19194956T patent/ES2931319T3/es active Active
- 2011-07-14 HU HUE11807523A patent/HUE031506T2/en unknown
- 2011-07-14 CA CA2804640A patent/CA2804640C/en active Active
- 2011-07-14 HU HUE19194956A patent/HUE060473T2/hu unknown
- 2011-07-14 DK DK11807523.3T patent/DK2593456T3/en active
- 2011-07-14 ES ES11807523T patent/ES2613700T3/es active Active
- 2011-07-14 PT PT191949569T patent/PT3597650T/pt unknown
- 2011-07-14 HR HRP20221430TT patent/HRP20221430T1/hr unknown
- 2011-07-14 EP EP19194956.9A patent/EP3597650B1/en active Active
- 2011-07-14 PL PL16187936T patent/PL3192796T3/pl unknown
- 2011-07-14 JP JP2013520752A patent/JP5934206B2/ja active Active
- 2011-07-14 ES ES16187936T patent/ES2769950T3/es active Active
- 2011-07-14 AU AU2011279058A patent/AU2011279058B2/en active Active
-
2016
- 2016-01-14 JP JP2016005570A patent/JP6165897B2/ja active Active
- 2016-10-20 HK HK16112126.4A patent/HK1223925A1/zh unknown
-
2017
- 2017-06-20 JP JP2017120238A patent/JP6306251B2/ja active Active
-
2018
- 2018-03-07 JP JP2018040694A patent/JP6430670B2/ja active Active
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