SMT201600319B - Metodi di selezione e amplificazione di polinucleotidi - Google Patents
Metodi di selezione e amplificazione di polinucleotidiInfo
- Publication number
- SMT201600319B SMT201600319B SM201600319T SM201600319T SMT201600319B SM T201600319 B SMT201600319 B SM T201600319B SM 201600319 T SM201600319 T SM 201600319T SM 201600319 T SM201600319 T SM 201600319T SM T201600319 B SMT201600319 B SM T201600319B
- Authority
- SM
- San Marino
- Prior art keywords
- polyucleotid
- amplification
- selection methods
- selection
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09848830.7A EP2470669B1 (en) | 2009-08-25 | 2009-08-25 | Methods for selecting and amplifying polynucleotides |
| PCT/US2009/054945 WO2011025477A1 (en) | 2009-08-25 | 2009-08-25 | Methods for selecting and amplifying polynucleotides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SMT201600319B true SMT201600319B (it) | 2016-11-10 |
Family
ID=43628274
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SM201600319T SMT201600319B (it) | 2009-08-25 | 2016-09-15 | Metodi di selezione e amplificazione di polinucleotidi |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US8999642B2 (it) |
| EP (3) | EP2669387B1 (it) |
| CN (1) | CN102597256B (it) |
| CA (1) | CA2770389C (it) |
| CY (1) | CY1117970T1 (it) |
| DK (2) | DK2669387T3 (it) |
| ES (2) | ES2595055T3 (it) |
| HR (1) | HRP20161056T1 (it) |
| HU (1) | HUE030765T2 (it) |
| LT (1) | LT2669387T (it) |
| PL (1) | PL2669387T3 (it) |
| PT (1) | PT2669387T (it) |
| SI (1) | SI2669387T1 (it) |
| SM (1) | SMT201600319B (it) |
| WO (1) | WO2011025477A1 (it) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010028288A2 (en) | 2008-09-05 | 2010-03-11 | Aueon, Inc. | Methods for stratifying and annotating cancer drug treatment options |
| WO2010038042A1 (en) | 2008-10-02 | 2010-04-08 | Illumina Cambridge Ltd. | Nucleic acid sample enrichment for sequencing applications |
| US9029103B2 (en) | 2010-08-27 | 2015-05-12 | Illumina Cambridge Limited | Methods for sequencing polynucleotides |
| EP3572528A1 (en) | 2010-09-24 | 2019-11-27 | The Board of Trustees of the Leland Stanford Junior University | Direct capture, amplification and sequencing of target dna using immobilized primers |
| EP3246416A1 (en) | 2011-04-15 | 2017-11-22 | The Johns Hopkins University | Safe sequencing system |
| EP2912468B1 (en) | 2012-10-29 | 2018-09-12 | The Johns Hopkins University | Papanicolaou test for ovarian and endometrial cancers |
| US10927408B2 (en) | 2013-12-02 | 2021-02-23 | Personal Genome Diagnostics, Inc. | Method for evaluating minority variants in a sample |
| US10100355B2 (en) | 2013-12-09 | 2018-10-16 | Illumina, Inc. | Methods and compositions for targeted nucleic acid sequencing |
| WO2015103225A1 (en) * | 2013-12-31 | 2015-07-09 | Illumina, Inc. | Addressable flow cell using patterned electrodes |
| US9677132B2 (en) | 2014-01-16 | 2017-06-13 | Illumina, Inc. | Polynucleotide modification on solid support |
| US9944924B2 (en) | 2014-01-16 | 2018-04-17 | Illumina, Inc. | Polynucleotide modification on solid support |
| KR102001554B1 (ko) | 2014-01-16 | 2019-07-18 | 일루미나, 인코포레이티드 | 고형 지지체 상에서의 앰플리콘 제조 방법 및 시퀀싱 |
| AU2015259024B2 (en) * | 2014-05-16 | 2021-07-01 | Illumina, Inc. | Nucleic acid synthesis techniques |
| US20150353989A1 (en) * | 2014-06-09 | 2015-12-10 | Illumina Cambridge Limited | Sample preparation for nucleic acid amplification |
| GB201410646D0 (en) * | 2014-06-14 | 2014-07-30 | Illumina Cambridge Ltd | Methods of increasing sequencing accuracy |
| US10619204B2 (en) | 2014-11-11 | 2020-04-14 | Illumina Cambridge Limited | Methods and arrays for producing and sequencing monoclonal clusters of nucleic acid |
| CN106148482B (zh) * | 2015-03-24 | 2019-12-03 | 深圳华大智造科技有限公司 | 一种适用于小型测序仪的测序方法 |
| EP3329012B1 (en) * | 2015-07-27 | 2021-07-21 | Illumina, Inc. | Spatial mapping of nucleic acid sequence information |
| WO2017027653A1 (en) | 2015-08-11 | 2017-02-16 | The Johns Hopkins University | Assaying ovarian cyst fluid |
| JP6913089B2 (ja) | 2015-11-11 | 2021-08-04 | レゾリューション バイオサイエンス， インコーポレイテッド | Ｄｎａライブラリーの高効率構築 |
| CA3005430A1 (en) * | 2015-11-16 | 2017-05-26 | Revere Biosensors, Llc | Systems and methods for identifying and distinguishing genetic samples |
| US10894990B2 (en) | 2016-05-17 | 2021-01-19 | Shoreline Biome, Llc | High throughput method for identification and sequencing of unknown microbial and eukaryotic genomes from complex mixtures |
| RU2019108294A (ru) | 2016-08-25 | 2020-09-25 | Резолюшн Байосайенс, Инк. | Способы обнаружения изменений количества геномных копий в образцах днк |
| GB201615233D0 (en) * | 2016-09-08 | 2016-10-26 | Bbi Solutions Oem Ltd | Solid Phase Conjugate |
| JP7430301B2 (ja) | 2017-05-09 | 2024-02-13 | リヴィア バイオセンサーズ，エルエルシー | 遺伝子サンプルを識別且つ区別するためのシステムと方法 |
| US10704094B1 (en) * | 2018-11-14 | 2020-07-07 | Element Biosciences, Inc. | Multipart reagents having increased avidity for polymerase binding |
| US10876148B2 (en) | 2018-11-14 | 2020-12-29 | Element Biosciences, Inc. | De novo surface preparation and uses thereof |
| ES2965266T3 (es) * | 2020-03-09 | 2024-04-11 | Illumina Inc | Métodos para la secuenciación de polinucleótidos |
| CN115777024A (zh) * | 2020-09-14 | 2023-03-10 | 伊鲁米纳公司 | 用于扩增多核苷酸的组合物和方法 |
| US11859241B2 (en) | 2021-06-17 | 2024-01-02 | Element Biosciences, Inc. | Compositions and methods for pairwise sequencing |
| US11535892B1 (en) | 2021-06-17 | 2022-12-27 | Element Biosciences, Inc. | Compositions and methods for pairwise sequencing |
| WO2023076833A1 (en) * | 2021-10-26 | 2023-05-04 | Singular Genomics Systems, Inc. | Multiplexed targeted amplification of polynucleotides |
| US20230348973A1 (en) * | 2022-03-31 | 2023-11-02 | Illumina Cambridge Limited | Paired-end re-synthesis using blocked p5 primers |
Family Cites Families (89)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4292503A (en) | 1979-05-14 | 1981-09-29 | Emerson Electric Co. | Split-band electric heater |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| EP0224126A3 (en) | 1985-11-25 | 1989-02-01 | The University of Calgary | Covalently linked complementary oligodeoxynucleotides as universal nucleic acid sequencing primer linkers |
| CA1340843C (en) | 1987-07-31 | 1999-12-07 | J. Lawrence Burg | Selective amplification of target polynucleotide sequences |
| SE8801070D0 (sv) | 1988-03-23 | 1988-03-23 | Pharmacia Ab | Method for immobilizing a dna sequence on a solid support |
| US6107023A (en) | 1988-06-17 | 2000-08-22 | Genelabs Technologies, Inc. | DNA amplification and subtraction techniques |
| GB8818020D0 (en) | 1988-07-28 | 1988-09-01 | Ici Plc | Method for amplification of nucleotide sequences |
| CA2004326A1 (en) | 1988-12-23 | 1990-06-23 | Nanibushan Dattagupta | Assay of sequences using amplified genes |
| US5629158A (en) | 1989-03-22 | 1997-05-13 | Cemu Bitecknik Ab | Solid phase diagnosis of medical conditions |
| US5800992A (en) | 1989-06-07 | 1998-09-01 | Fodor; Stephen P.A. | Method of detecting nucleic acids |
| US5547839A (en) | 1989-06-07 | 1996-08-20 | Affymax Technologies N.V. | Sequencing of surface immobilized polymers utilizing microflourescence detection |
| US5302509A (en) | 1989-08-14 | 1994-04-12 | Beckman Instruments, Inc. | Method for sequencing polynucleotides |
| JP3096722B2 (ja) | 1990-01-17 | 2000-10-10 | 日本ケミカルリサーチ株式会社 | ポリメラーゼ・チェーン・リアクション用プライマーの作製法およびそれを用いるｄｎａの増幅法 |
| US5118604A (en) | 1990-06-15 | 1992-06-02 | Yale University | Restriction-fragment DNA probes and probe clusters |
| WO1993004199A2 (en) | 1991-08-20 | 1993-03-04 | Scientific Generics Limited | Methods of detecting or quantitating nucleic acids and of producing labelled immobilised nucleic acids |
| WO1993006239A1 (en) | 1991-09-24 | 1993-04-01 | Keygene N.V. | Selective restriction fragment amplification: a general method for dna fingerprinting |
| AU3728093A (en) | 1992-02-19 | 1993-09-13 | Public Health Research Institute Of The City Of New York, Inc., The | Novel oligonucleotide arrays and their use for sorting, isolating, sequencing, and manipulating nucleic acids |
| US5849544A (en) | 1992-07-24 | 1998-12-15 | University Of Australia | Amplification and detection process |
| RU2048522C1 (ru) | 1992-10-14 | 1995-11-20 | Институт белка РАН | Способ размножения нуклеиновых кислот, способ их экспрессии и среда для их осуществления |
| JPH07203998A (ja) | 1994-01-26 | 1995-08-08 | Hamamatsu Photonics Kk | 核酸塩基配列決定方法 |
| NZ287118A (en) | 1994-05-28 | 1999-01-28 | Tepnel Medical Ltd | Method of detecting and amplifying oligonucleotides |
| US5641658A (en) | 1994-08-03 | 1997-06-24 | Mosaic Technologies, Inc. | Method for performing amplification of nucleic acid with two primers bound to a single solid support |
| US6060288A (en) | 1994-08-03 | 2000-05-09 | Mosaic Technologies | Method for performing amplification of nucleic acid on supports |
| US6090592A (en) | 1994-08-03 | 2000-07-18 | Mosaic Technologies, Inc. | Method for performing amplification of nucleic acid on supports |
| JPH11503611A (ja) | 1995-04-11 | 1999-03-30 | トラスティーズ・オブ・ボストン・ユニバーシティ | 生体高分子の固相配列決定法 |
| US5750341A (en) | 1995-04-17 | 1998-05-12 | Lynx Therapeutics, Inc. | DNA sequencing by parallel oligonucleotide extensions |
| DE19515552A1 (de) | 1995-04-27 | 1996-10-31 | Europ Lab Molekularbiolog | Simultane Sequenzierung von Nukleinsäuren |
| SE9504099D0 (sv) | 1995-11-16 | 1995-11-16 | Pharmacia Biotech Ab | A method of sequencing |
| US5935788A (en) | 1996-06-25 | 1999-08-10 | Lifespan Biosciences, Inc. | Subtractive hybridization techniques for identifying differentially expressed and commonly expressed nucleic acid |
| US5837466A (en) | 1996-12-16 | 1998-11-17 | Vysis, Inc. | Devices and methods for detecting nucleic acid analytes in samples |
| US20020061532A1 (en) | 1997-02-14 | 2002-05-23 | Mosaic Technologies, Inc. | Method and apparatus for performing amplification of nucleic acids on supports |
| ES2563643T3 (es) | 1997-04-01 | 2016-03-15 | Illumina Cambridge Limited | Método de secuenciación de ácido nucleico |
| US20020055100A1 (en) | 1997-04-01 | 2002-05-09 | Kawashima Eric H. | Method of nucleic acid sequencing |
| US6534273B2 (en) * | 1997-05-02 | 2003-03-18 | Gen-Probe Incorporated | Two-step hybridization and capture of a polynucleotide |
| US6326489B1 (en) | 1997-08-05 | 2001-12-04 | Howard Hughes Medical Institute | Surface-bound, bimolecular, double-stranded DNA arrays |
| US6087099A (en) | 1997-09-08 | 2000-07-11 | Myriad Genetics, Inc. | Method for sequencing both strands of a double stranded DNA in a single sequencing reaction |
| US6511803B1 (en) | 1997-10-10 | 2003-01-28 | President And Fellows Of Harvard College | Replica amplification of nucleic acid arrays |
| US20030022207A1 (en) | 1998-10-16 | 2003-01-30 | Solexa, Ltd. | Arrayed polynucleotides and their use in genome analysis |
| AR021833A1 (es) | 1998-09-30 | 2002-08-07 | Applied Research Systems | Metodos de amplificacion y secuenciacion de acido nucleico |
| ATE316152T1 (de) | 1998-10-27 | 2006-02-15 | Affymetrix Inc | Komplexitätsmanagement und analyse genomischer dna |
| US6238868B1 (en) | 1999-04-12 | 2001-05-29 | Nanogen/Becton Dickinson Partnership | Multiplex amplification and separation of nucleic acid sequences using ligation-dependant strand displacement amplification and bioelectronic chip technology |
| US20060275782A1 (en) | 1999-04-20 | 2006-12-07 | Illumina, Inc. | Detection of nucleic acid reactions on bead arrays |
| US20030108867A1 (en) | 1999-04-20 | 2003-06-12 | Chee Mark S | Nucleic acid sequencing using microsphere arrays |
| US6300070B1 (en) | 1999-06-04 | 2001-10-09 | Mosaic Technologies, Inc. | Solid phase methods for amplifying multiple nucleic acids |
| DE10051564A1 (de) | 2000-10-18 | 2002-08-01 | Axaron Bioscience Ag | Neue Verfahren zur parallelen Sequenzierung eines Nukleinsäuregemisches an einer Oberfläche |
| ATE317024T1 (de) | 1999-12-29 | 2006-02-15 | Keygene Nv | Verfahren zur erzeugung von oligonukleotiden, im besonderen zur detektion amplifizierter restriktionsfragmente, die durch aflp erhalten wurden |
| US7955794B2 (en) | 2000-09-21 | 2011-06-07 | Illumina, Inc. | Multiplex nucleic acid reactions |
| AU2001251582A1 (en) | 2000-04-14 | 2001-10-30 | Lynx Therapeutics, Inc. | Method and compositions for ordering restriction fragments |
| AR031640A1 (es) | 2000-12-08 | 2003-09-24 | Applied Research Systems | Amplificacion isotermica de acidos nucleicos en un soporte solido |
| AU2002245988A1 (en) * | 2001-04-18 | 2002-10-28 | Ulrich J. Krull | Gradient resolved hybridisation platform |
| EP1256632A3 (en) | 2001-05-07 | 2004-01-02 | Smithkline Beecham Corporation | High throughput polymorphism screening |
| EP1472335A4 (en) | 2001-11-08 | 2005-12-28 | Univ Johns Hopkins | METHOD AND SYSTEMS FOR NUCLEIC ACID SEQUENCING |
| US7057026B2 (en) | 2001-12-04 | 2006-06-06 | Solexa Limited | Labelled nucleotides |
| EP1483404A2 (en) | 2002-03-05 | 2004-12-08 | Solexa Ltd. | Methods for detecting genome-wide sequence variations associated with a phenotype |
| US20040002090A1 (en) | 2002-03-05 | 2004-01-01 | Pascal Mayer | Methods for detecting genome-wide sequence variations associated with a phenotype |
| AU2003242605A1 (en) * | 2002-06-03 | 2003-12-19 | Pamgene B.V. | Novel high density arrays and methods for analyte analysis |
| US9388459B2 (en) | 2002-06-17 | 2016-07-12 | Affymetrix, Inc. | Methods for genotyping |
| ES2407681T3 (es) | 2002-08-23 | 2013-06-13 | Illumina Cambridge Limited | Nucleótidos modificados para la secuenciación de polinucleótidos. |
| US20040126765A1 (en) | 2002-12-27 | 2004-07-01 | Adams Craig W. | Method and compositions for sequencing nucleic acid molecules |
| ES2338654T5 (es) | 2003-01-29 | 2017-12-11 | 454 Life Sciences Corporation | Amplificación de ácidos nucleicos en emulsión de perlas |
| EP1592810A2 (en) | 2003-02-12 | 2005-11-09 | Genizon Svenska AB | Methods and means for nucleic acid sequencing |
| GB0324456D0 (en) | 2003-10-20 | 2003-11-19 | Isis Innovation | Parallel DNA sequencing methods |
| WO2005042781A2 (en) | 2003-10-31 | 2005-05-12 | Agencourt Personal Genomics Corporation | Methods for producing a paired tag from a nucleic acid sequence and methods of use thereof |
| GB0400584D0 (en) | 2004-01-12 | 2004-02-11 | Solexa Ltd | Nucleic acid chacterisation |
| GB2412170A (en) | 2004-03-16 | 2005-09-21 | Plant Bioscience Ltd | A method for enriching for target nucleic acids in a sample |
| GB2413796B (en) | 2004-03-25 | 2006-03-29 | Global Genomics Ab | Methods and means for nucleic acid sequencing |
| US20070003924A1 (en) | 2004-06-18 | 2007-01-04 | The Ohio State University Research Foundation | Serial analysis of ribosomal and other microbial sequence tags |
| US20060078899A1 (en) | 2004-10-12 | 2006-04-13 | Scheffer Alicia F | Methods and compositions for reducing label variation in array-based comparative genome hybridization assays |
| CA2604095A1 (en) | 2005-04-12 | 2006-10-19 | 454 Life Sciences Corporation | Methods for determining sequence variants using ultra-deep sequencing |
| WO2007145612A1 (en) | 2005-06-06 | 2007-12-21 | 454 Life Sciences Corporation | Paired end sequencing |
| US8428882B2 (en) | 2005-06-14 | 2013-04-23 | Agency For Science, Technology And Research | Method of processing and/or genome mapping of diTag sequences |
| GB0514935D0 (en) | 2005-07-20 | 2005-08-24 | Solexa Ltd | Methods for sequencing a polynucleotide template |
| GB0514936D0 (en) | 2005-07-20 | 2005-08-24 | Solexa Ltd | Preparation of templates for nucleic acid sequencing |
| GB0514910D0 (en) | 2005-07-20 | 2005-08-24 | Solexa Ltd | Method for sequencing a polynucleotide template |
| GB0522310D0 (en) | 2005-11-01 | 2005-12-07 | Solexa Ltd | Methods of preparing libraries of template polynucleotides |
| ATE483804T1 (de) | 2006-01-04 | 2010-10-15 | Si Lok | Verfahren zur zuordnung von nukleinsäuren und zur identifikation fein strukturierter variationen in nukleinsäuren sowie hilfsmittel dafür |
| WO2007091077A1 (en) | 2006-02-08 | 2007-08-16 | Solexa Limited | Method for sequencing a polynucleotide template |
| EP2021503A1 (en) * | 2006-03-17 | 2009-02-11 | Solexa Ltd. | Isothermal methods for creating clonal single molecule arrays |
| US20070231823A1 (en) | 2006-03-23 | 2007-10-04 | Mckernan Kevin J | Directed enrichment of genomic DNA for high-throughput sequencing |
| EP3373174A1 (en) | 2006-03-31 | 2018-09-12 | Illumina, Inc. | Systems and devices for sequence by synthesis analysis |
| US8178360B2 (en) | 2006-05-18 | 2012-05-15 | Illumina Cambridge Limited | Dye compounds and the use of their labelled conjugates |
| US8921073B2 (en) | 2006-06-23 | 2014-12-30 | Illumina, Inc. | Devices and systems for creation of DNA cluster arrays |
| US7754429B2 (en) | 2006-10-06 | 2010-07-13 | Illumina Cambridge Limited | Method for pair-wise sequencing a plurity of target polynucleotides |
| GB0712882D0 (en) | 2007-07-03 | 2007-08-15 | Leicester University Of | Nucleic acid amplification |
| WO2009032167A1 (en) | 2007-08-29 | 2009-03-12 | Illumina Cambridge | Method for sequencing a polynucleotide template |
| JP2009178159A (ja) | 2007-11-05 | 2009-08-13 | Hitachi Plant Technologies Ltd | 核酸配列の検出方法及び核酸配列検出基板 |
| WO2010038042A1 (en) | 2008-10-02 | 2010-04-08 | Illumina Cambridge Ltd. | Nucleic acid sample enrichment for sequencing applications |
| EP3572528A1 (en) | 2010-09-24 | 2019-11-27 | The Board of Trustees of the Leland Stanford Junior University | Direct capture, amplification and sequencing of target dna using immobilized primers |
| WO2013117595A2 (en) * | 2012-02-07 | 2013-08-15 | Illumina Cambridge Limited | Targeted enrichment and amplification of nucleic acids on a support |
-
2009
- 2009-08-25 ES ES13180255.5T patent/ES2595055T3/es active Active
- 2009-08-25 WO PCT/US2009/054945 patent/WO2011025477A1/en active Application Filing
- 2009-08-25 PL PL13180255.5T patent/PL2669387T3/pl unknown
- 2009-08-25 ES ES16180028T patent/ES2763386T3/es active Active
- 2009-08-25 EP EP13180255.5A patent/EP2669387B1/en active Active
- 2009-08-25 SI SI200931517A patent/SI2669387T1/sl unknown
- 2009-08-25 CA CA2770389A patent/CA2770389C/en active Active
- 2009-08-25 DK DK13180255.5T patent/DK2669387T3/en active
- 2009-08-25 HU HUE13180255A patent/HUE030765T2/en unknown
- 2009-08-25 DK DK16180028.9T patent/DK3133169T3/da active
- 2009-08-25 PT PT131802555T patent/PT2669387T/pt unknown
- 2009-08-25 EP EP16180028.9A patent/EP3133169B1/en active Active
- 2009-08-25 CN CN200980162143.XA patent/CN102597256B/zh active Active
- 2009-08-25 EP EP09848830.7A patent/EP2470669B1/en active Active
- 2009-08-25 US US13/387,078 patent/US8999642B2/en active Active
- 2009-08-25 LT LTEP13180255.5T patent/LT2669387T/lt unknown
-
2015
- 2015-02-02 US US14/611,991 patent/US9624489B2/en active Active
-
2016
- 2016-08-22 HR HRP20161056TT patent/HRP20161056T1/hr unknown
- 2016-09-05 CY CY20161100871T patent/CY1117970T1/el unknown
- 2016-09-15 SM SM201600319T patent/SMT201600319B/it unknown
-
2017
- 2017-04-17 US US15/489,549 patent/US10597653B2/en active Active
-
2020
- 2020-02-10 US US16/786,198 patent/US11142759B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US11142759B2 (en) | 2021-10-12 |
| WO2011025477A1 (en) | 2011-03-03 |
| ES2763386T3 (es) | 2020-05-28 |
| CN102597256A (zh) | 2012-07-18 |
| LT2669387T (lt) | 2016-10-25 |
| CY1117970T1 (el) | 2017-05-17 |
| EP2470669B1 (en) | 2014-06-18 |
| ES2595055T3 (es) | 2016-12-27 |
| SI2669387T1 (sl) | 2017-01-31 |
| EP3133169B1 (en) | 2019-10-16 |
| EP3133169A1 (en) | 2017-02-22 |
| DK3133169T3 (da) | 2019-12-16 |
| US10597653B2 (en) | 2020-03-24 |
| US8999642B2 (en) | 2015-04-07 |
| DK2669387T3 (en) | 2016-09-19 |
| PT2669387T (pt) | 2016-09-20 |
| CA2770389A1 (en) | 2011-03-03 |
| EP2669387B1 (en) | 2016-07-20 |
| US9624489B2 (en) | 2017-04-18 |
| CN102597256B (zh) | 2014-12-03 |
| US20200239875A1 (en) | 2020-07-30 |
| US20150148263A1 (en) | 2015-05-28 |
| HRP20161056T1 (hr) | 2016-12-16 |
| PL2669387T3 (pl) | 2016-12-30 |
| HUE030765T2 (en) | 2017-05-29 |
| EP2669387A1 (en) | 2013-12-04 |
| EP2470669A4 (en) | 2013-01-30 |
| US20170283794A1 (en) | 2017-10-05 |
| EP2470669A1 (en) | 2012-07-04 |
| US20120122737A1 (en) | 2012-05-17 |
| CA2770389C (en) | 2015-12-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SMT201600319B (it) | Metodi di selezione e amplificazione di polinucleotidi | |
| BRPI0907231A2 (pt) | pirrolpirimidinas e pirrolpiridinas | |
| BRPI1006537A2 (pt) | método e artigo | |
| BRPI1008827A2 (pt) | deisobutenizador | |
| BRPI1014968A2 (pt) | subalargador | |
| DE112010002728A5 (de) | Turboinhalator | |
| BRPI1013338A2 (pt) | processos e intermediários | |
| DE112009005323A5 (de) | Hebelarmprüfmaschine | |
| BR112012004964A2 (pt) | girocóptero | |
| BRPI1008070A2 (pt) | tricianoboratos | |
| DK3192796T3 (da) | Aldosereduktaseinhibitorer og anvendelser deraf | |
| BRPI1011397A2 (pt) | atenuador | |
| BRPI1014641A2 (pt) | arilpirrolidinas pesticidas | |
| BR112012010510A2 (pt) | trator | |
| FR2952291B3 (fr) | Grill | |
| BRPI1010159A2 (pt) | bistuti | |
| DK2406372T3 (da) | Prægastrisk esterase og derivater deraf | |
| DK2279652T3 (da) | Kultivator | |
| BR112012003616A2 (pt) | metilpirroloprimidinacarboxamidas | |
| DE112010002351A5 (de) | Klemmorrichtung | |
| FI20095782A (fi) | Tulipesä | |
| BRPI1014810A2 (pt) | Métodos e formulações ectoparasiticidas | |
| FR2949540B3 (fr) | Cheminee | |
| DE112010004907A5 (de) | Dämpfungseinrichtung | |
| DE102009039027A8 (de) | Abziehvorrichtung |