DK314483A - Peenem-derivater, fremgangsmaade til fremstilling deraf samt deres anvendelse som laegemidler - Google Patents

Peenem-derivater, fremgangsmaade til fremstilling deraf samt deres anvendelse som laegemidler Download PDF

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Publication number
DK314483A
DK314483A DK314483A DK314483A DK314483A DK 314483 A DK314483 A DK 314483A DK 314483 A DK314483 A DK 314483A DK 314483 A DK314483 A DK 314483A DK 314483 A DK314483 A DK 314483A
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DK
Denmark
Prior art keywords
sup
derivatives
peenem
medicines
procedures
Prior art date
Application number
DK314483A
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English (en)
Other versions
DK314483D0 (da
Inventor
Michael Davis Cooke
Barry Clive Ross
Original Assignee
Hoechst Uk Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Uk Ltd filed Critical Hoechst Uk Ltd
Publication of DK314483D0 publication Critical patent/DK314483D0/da
Publication of DK314483A publication Critical patent/DK314483A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/86—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with only atoms other than nitrogen atoms directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/34—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
DK314483A 1982-07-08 1983-07-07 Peenem-derivater, fremgangsmaade til fremstilling deraf samt deres anvendelse som laegemidler DK314483A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8219745 1982-07-08

Publications (2)

Publication Number Publication Date
DK314483D0 DK314483D0 (da) 1983-07-07
DK314483A true DK314483A (da) 1984-01-09

Family

ID=10531540

Family Applications (1)

Application Number Title Priority Date Filing Date
DK314483A DK314483A (da) 1982-07-08 1983-07-07 Peenem-derivater, fremgangsmaade til fremstilling deraf samt deres anvendelse som laegemidler

Country Status (22)

Country Link
US (1) US4738959A (da)
EP (1) EP0099059B1 (da)
JP (1) JPS5921693A (da)
KR (1) KR900007181B1 (da)
AT (1) ATE35270T1 (da)
AU (1) AU567103B2 (da)
CA (1) CA1227194A (da)
DE (1) DE3377132D1 (da)
DK (1) DK314483A (da)
ES (3) ES8504203A1 (da)
FI (1) FI77662C (da)
GB (2) GB2122619B (da)
GR (1) GR78890B (da)
HU (3) HU193459B (da)
IE (1) IE55581B1 (da)
IL (1) IL69174A0 (da)
MA (1) MA19842A1 (da)
NO (3) NO832487L (da)
NZ (1) NZ204829A (da)
PH (1) PH23148A (da)
PT (1) PT76996B (da)
ZA (1) ZA834955B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE28648T1 (de) * 1982-03-26 1987-08-15 Hoechst Uk Ltd 7-oxo-4-thia-1-azabicyclo(3,2,0)heptan-derivate
GB2197865B (en) * 1984-06-29 1989-05-17 Hoechst Uk Ltd Azetidinone derivatives
GB2197864B (en) * 1984-06-29 1989-05-17 Hoechst Uk Ltd Antibacterial 7-oxo-4-thia-1-azabicyclo(3.2.0)-hept-2-ene derivatives
GB8416565D0 (en) * 1984-06-29 1984-08-01 Hoechst Uk Ltd Antibacterial derivatives
GB2164334B (en) * 1984-09-10 1988-08-03 Hoechst Uk Ltd Antibacterial 7-oxo-4-thia-1-azabicyclo 3,2,0 hept-2-ene derivativess
JPS61236785A (ja) * 1985-04-15 1986-10-22 Sankyo Co Ltd アゼチジノン誘導体
US4868296A (en) * 1985-10-29 1989-09-19 Pfizer Inc. 6-(1-carbamoyl-1-hydroxymethyl) penicillanic acid derivatives
WO1990006928A1 (en) * 1985-10-29 1990-06-28 Barth Wayne E 6-(1-carbamoyl-1-hydroxymethyl)penicillanic acid derivatives
JPS62179860A (ja) * 1986-01-31 1987-08-07 Sintokogio Ltd 低圧鋳造装置

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4301074A (en) * 1977-11-17 1981-11-17 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-substituted-pen-2-em-3-carboxylic acid
US4168314A (en) * 1977-11-17 1979-09-18 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
EP0042026B1 (de) * 1978-02-02 1986-01-08 Ciba-Geigy Ag 3,4-Disubstituierte Azetidin-2-onverbindungen und Verfahren zu ihrer Herstellung
JPS5625110A (en) * 1978-12-18 1981-03-10 Bristol Myers Co Antibacterial
JPS56115788A (en) * 1980-02-19 1981-09-11 Sankyo Co Ltd Azetidinone derivative and its preparation
CH651037A5 (de) * 1980-06-06 1985-08-30 Sankyo Co Penem-3-carbonsaeurederivate und verfahren zu deren herstellung.
DE3167198D1 (en) * 1980-08-16 1984-12-20 Beecham Group Plc Process for the preparation of 2-thio penem derivatives and intermediates therefor
US4431658A (en) * 1981-02-02 1984-02-14 Schering Corporation Aza penem compounds
US4347183A (en) * 1981-02-02 1982-08-31 Schering Corporation Process for the synthesis of penems and carbapenems
ES513672A0 (es) * 1981-07-08 1983-04-01 Hoechst Uk Ltd "procedimiento para la preparacion de derivados de penem".
DE3274982D1 (en) * 1981-07-08 1987-02-12 Hoechst Uk Ltd Antibacterial penem derivatives

Also Published As

Publication number Publication date
CA1227194A (en) 1987-09-22
GB8318513D0 (en) 1983-08-10
ES523890A0 (es) 1985-04-01
JPS5921693A (ja) 1984-02-03
NO842960L (no) 1984-01-09
FI832479A0 (fi) 1983-07-06
IL69174A0 (en) 1983-11-30
PT76996A (en) 1983-08-01
HU193459B (en) 1987-10-28
FI77662B (fi) 1988-12-30
EP0099059A1 (en) 1984-01-25
HUT40622A (en) 1987-01-28
ATE35270T1 (de) 1988-07-15
GB2122619A (en) 1984-01-18
IE55581B1 (en) 1990-11-07
GB2122619B (en) 1986-01-08
GR78890B (da) 1984-10-02
AU567103B2 (en) 1987-11-12
GB2160865A (en) 1986-01-02
HU193460B (en) 1987-10-28
ZA834955B (en) 1984-03-28
GB2160865B (en) 1986-11-26
DE3377132D1 (en) 1988-07-28
HU192819B (en) 1987-07-28
ES539161A0 (es) 1985-11-01
NZ204829A (en) 1986-07-11
PH23148A (en) 1989-05-11
GB8515248D0 (en) 1985-07-17
NO832487L (no) 1984-01-09
DK314483D0 (da) 1983-07-07
ES539160A0 (es) 1985-11-01
KR840005453A (ko) 1984-11-12
MA19842A1 (fr) 1984-04-01
FI832479L (fi) 1984-01-09
AU1665383A (en) 1984-01-12
PT76996B (en) 1986-03-12
ES8602013A1 (es) 1985-11-01
ES8601875A1 (es) 1985-11-01
FI77662C (fi) 1989-04-10
NO841108L (no) 1984-01-09
US4738959A (en) 1988-04-19
KR900007181B1 (ko) 1990-09-29
ES8504203A1 (es) 1985-04-01
IE831592L (en) 1984-01-08
EP0099059B1 (en) 1988-06-22

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