DK3110434T3 - UTI FUSION PROTEINS - Google Patents

Info

Publication number

DK3110434T3

DK3110434T3 DK15708411.2T DK15708411T DK3110434T3 DK 3110434 T3 DK3110434 T3 DK 3110434T3 DK 15708411 T DK15708411 T DK 15708411T DK 3110434 T3 DK3110434 T3 DK 3110434T3

Authority

DK

Denmark

Prior art keywords

gly

ser

val

glu

lys

Prior art date

2014-02-24

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• 108020001507 fusion proteins Proteins 0.000 title claims description 115
• 102000037865 fusion proteins Human genes 0.000 title claims description 115
• 108091033319 polynucleotide Proteins 0.000 claims description 29
• 102000040430 polynucleotide Human genes 0.000 claims description 29
• 239000002157 polynucleotide Substances 0.000 claims description 28
• 238000011282 treatment Methods 0.000 claims description 20
• 150000007523 nucleic acids Chemical class 0.000 claims description 18
• 102000039446 nucleic acids Human genes 0.000 claims description 15
• 108020004707 nucleic acids Proteins 0.000 claims description 15
• 239000013604 expression vector Substances 0.000 claims description 14
• 239000008194 pharmaceutical composition Substances 0.000 claims description 10
• 206010033645 Pancreatitis Diseases 0.000 claims description 9
• 239000000546 pharmaceutical excipient Substances 0.000 claims description 8
• 239000000539 dimer Substances 0.000 claims description 7
• 238000004519 manufacturing process Methods 0.000 claims description 7
• 206010035664 Pneumonia Diseases 0.000 claims description 5
• 239000003814 drug Substances 0.000 claims description 5
• 206010009192 Circulatory collapse Diseases 0.000 claims description 4
• 206010042033 Stevens-Johnson syndrome Diseases 0.000 claims description 4
• 206010051379 Systemic Inflammatory Response Syndrome Diseases 0.000 claims description 4
• 206010069351 acute lung injury Diseases 0.000 claims description 4
• 239000001963 growth medium Substances 0.000 claims description 4
• 210000003734 kidney Anatomy 0.000 claims description 4
• 230000035939 shock Effects 0.000 claims description 4
• 206010001052 Acute respiratory distress syndrome Diseases 0.000 claims description 3
• 206010033647 Pancreatitis acute Diseases 0.000 claims description 3
• 206010040047 Sepsis Diseases 0.000 claims description 3
• 201000003229 acute pancreatitis Diseases 0.000 claims description 3
• 208000009190 disseminated intravascular coagulation Diseases 0.000 claims description 3
• 206010003011 Appendicitis Diseases 0.000 claims description 2
• 208000002251 Dissecting Aneurysm Diseases 0.000 claims description 2
• 206010053159 Organ failure Diseases 0.000 claims description 2
• 206010063837 Reperfusion injury Diseases 0.000 claims description 2
• 201000003176 Severe Acute Respiratory Syndrome Diseases 0.000 claims description 2
• 231100000168 Stevens-Johnson syndrome Toxicity 0.000 claims description 2
• 206010044223 Toxic epidermal necrolysis Diseases 0.000 claims description 2
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• 230000001154 acute effect Effects 0.000 claims description 2
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• 208000006673 asthma Diseases 0.000 claims description 2
• 206010009887 colitis Diseases 0.000 claims description 2
• 238000001839 endoscopy Methods 0.000 claims description 2
• 208000006454 hepatitis Diseases 0.000 claims description 2
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