DK3016946T3 - Substituerede benzofuranyl- og benzoxazolylforbindelser og anvendelser deraf - Google Patents

Substituerede benzofuranyl- og benzoxazolylforbindelser og anvendelser deraf Download PDF

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Publication number
DK3016946T3
DK3016946T3 DK14742127.5T DK14742127T DK3016946T3 DK 3016946 T3 DK3016946 T3 DK 3016946T3 DK 14742127 T DK14742127 T DK 14742127T DK 3016946 T3 DK3016946 T3 DK 3016946T3
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Prior art keywords
substituted benzofuranyl
benzoxazolyl compounds
benzoxazolyl
compounds
benzofuranyl
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DK14742127.5T
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English (en)
Inventor
Erkan Baloglu
Yosef Landesman
Gali Golan
Ori Kalid
Sharon Shechter
Sharon Shacham
William Senapedis
Dilara Mccauley
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Karyopharm Therapeutics Inc
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    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81—Radicals substituted by nitrogen atoms not forming part of a nitro radical
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • C07D491/10—Spiro-condensed systems
    • C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
DK14742127.5T 2013-07-03 2014-07-03 Substituerede benzofuranyl- og benzoxazolylforbindelser og anvendelser deraf DK3016946T3 (da)

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US201361842856P 2013-07-03 2013-07-03
US201361879070P 2013-09-17 2013-09-17
US201361904843P 2013-11-15 2013-11-15
US201461975171P 2014-04-04 2014-04-04
PCT/US2014/045479 WO2015003166A1 (en) 2013-07-03 2014-07-03 Substituted benzofuranyl and benzoxazolyl compounds and uses thereof

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US (4) US9856241B2 (da)
EP (1) EP3016946B1 (da)
JP (2) JP6397010B2 (da)
KR (2) KR102581373B1 (da)
CN (2) CN108440515B (da)
AU (2) AU2014285019C1 (da)
BR (1) BR112015032921B1 (da)
CA (1) CA2917315C (da)
DK (1) DK3016946T3 (da)
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