DK3007716T3 - Tetrapeptider afledt af humane c-x-c-chemokiner, der er nyttige til behandling af forskellige hudlidelser - Google Patents
Tetrapeptider afledt af humane c-x-c-chemokiner, der er nyttige til behandling af forskellige hudlidelser Download PDFInfo
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- DK3007716T3 DK3007716T3 DK14730697.1T DK14730697T DK3007716T3 DK 3007716 T3 DK3007716 T3 DK 3007716T3 DK 14730697 T DK14730697 T DK 14730697T DK 3007716 T3 DK3007716 T3 DK 3007716T3
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- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
- A61Q7/02—Preparations for inhibiting or slowing hair growth
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Birds (AREA)
- Toxicology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
Claims (12)
1. Isoleret tetrapeptid, der udviser sårhelings- og regenereringsaktivitet og består af peptidsekvensen (I eller V)-X1-K-X2, hvor X1 er E, Q eller K, og X2 er M, F, I, W, V eller L.
2. Tetrapeptid ifølge krav 1, der er SEQ ID NO:1 (IEKM), SEQ ID NO:2 (VEKF), SEQ ID NO:3 (IEKI), SEQ ID NO:4 (IQKI), SEQ ID NO:5 (IKKW), SEQ ID NO:6 (IKKV) eller SEQ ID NO:7 (IKKL).
3. Tetrapeptid ifølge krav 1, der omfatter enten L- eller D-aminosyreenantiomerer eller dem begge eller er konjugeret til et bærermolekyle, amideret eller lipideret.
4. Tetrapeptid ifølge krav 1, der er i fri syre-form.
5. Sammensætning der omfatter mindst ét tetrapeptid ifølge et hvilket som helst af kravene 1-4 og en farmaceutisk acceptabel bærer.
6. Sammensætning ifølge krav 5, hvor tetrapeptidet forekommer i en koncentration i intervallet fra ca. 0,1 pg/ml til ca. 500 pg/ml eller ca. 0,1 pg/ml til ca. 20 mg/ml.
7. Sammensætning ifølge krav 5, hvor sammensætningen er i form afen aerosol, en emulsion, en væske, en lotion, en opløsning, en gel, en mikroindkapsling, en creme, en pasta, en salve, et pulver eller et skum eller er inkorporeret i en indretning, som er tilpasset til påføring på hudens overflade eller under hudens væv.
8. Sammensætning til anvendelse ved heling af et sår eller behandling af en inflammatorisk hudlidelse hos et pattedyr ved påføring i en terapeutisk effektiv mængde af i et effektivt tidsrum, hvor medikamentet omfatter en farmaceutisk acceptabel bærer og mindst ét tetrapeptid ifølge et hvilket som helst af kravene 1-4.
9. Sammensætning til anvendelse ved en fremgangsmåde ifølge krav 8, hvor såret eller den inflammatoriske lidelse påvirker huden eller det relaterede slimhindevæv hos pattedyret.
10. Sammensætning til anvendelse i en fremgangsmåde ifølge krav 9, hvor såret skyldes en hudafskrabning, en blister, en forbrænding, en laceration, et ulcus, en kontusion, et udslæt, striae distensae, et ar, et strækmærke eller virkningerne af ældning eller miljøeksponering, eller den inflammatoriske lidelse skyldes psoriasis, atopisk dermatitis og rosacea, eller anvendelse til hårfjerning eller fjernelse af papilloma cutanea.
11. Sammensætning ifølge et hvilket som helst af kravene 5 til 7 til anvendelse ved hudplejebehandling.
12. Sammensætning ifølge et hvilket som helst af kravene 5 til 7 til anvendelse i et kosmetisk produkt.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361835424P | 2013-06-14 | 2013-06-14 | |
| PCT/US2014/037978 WO2014200651A1 (en) | 2013-06-14 | 2014-05-14 | Tetrapeptides derived from human c-x-c chemokines useful for treatment of various skin conditions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3007716T3 true DK3007716T3 (da) | 2017-07-31 |
Family
ID=50943603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14730697.1T DK3007716T3 (da) | 2013-06-14 | 2014-05-14 | Tetrapeptider afledt af humane c-x-c-chemokiner, der er nyttige til behandling af forskellige hudlidelser |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US10195245B2 (da) |
| EP (1) | EP3007716B1 (da) |
| JP (1) | JP6416240B2 (da) |
| KR (1) | KR102254260B1 (da) |
| CN (1) | CN105324122B (da) |
| AR (1) | AR096594A1 (da) |
| AU (1) | AU2014278708B2 (da) |
| BR (1) | BR112015031018B1 (da) |
| CA (1) | CA2915174C (da) |
| CY (1) | CY1119191T1 (da) |
| DK (1) | DK3007716T3 (da) |
| ES (1) | ES2631804T3 (da) |
| HK (1) | HK1217436A1 (da) |
| HU (1) | HUE032970T2 (da) |
| MX (1) | MX362846B (da) |
| MY (1) | MY168981A (da) |
| PL (1) | PL3007716T3 (da) |
| RU (1) | RU2687151C2 (da) |
| SG (1) | SG11201509048VA (da) |
| SI (1) | SI3007716T1 (da) |
| TW (1) | TWI511737B (da) |
| WO (1) | WO2014200651A1 (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110302088A (zh) * | 2019-04-29 | 2019-10-08 | 杭州肽佳生物科技有限公司 | 一种包含修饰芋螺肽的化妆品组合物 |
| EP4093369A1 (en) * | 2020-01-21 | 2022-11-30 | ASC Regenity Ltd. | Cosmetic formulation for topical administration comprising novel peptides that improve appearance and regeneration of skin |
| PL245202B1 (pl) | 2020-03-06 | 2024-06-03 | Gdanski Univ Medyczny | Lipopeptydowe koniugaty i ich sole, sposób wytwarzania lipopeptydowych koniugatów i ich soli, kompozycja farmaceutyczna zawierająca lipopeptydowy koniugat i jego sole do leczenia ran przewlekłych |
| WO2022098051A1 (ko) | 2020-11-05 | 2022-05-12 | 한국생명공학연구원 | 항염 및 조직 재생작용을 갖는 신규 펩타이드 |
| CN113698452B (zh) * | 2021-08-23 | 2023-08-18 | 四川丽妍工坊生物科技有限公司 | 一种促皮肤修复肽、制备方法及其应用 |
| CA3233983A1 (en) * | 2021-11-02 | 2023-05-11 | Ole-Jan Iversen (Deceased) | Tri-, tetra and pentapeptides, compositions thereof and their use in the therapy of psoriasis |
| CN116407611A (zh) * | 2021-12-29 | 2023-07-11 | 四川好医生攀西药业有限责任公司 | 一种多肽在制备预防或治疗皮肤损伤疾病产品上的应用 |
| KR20230156265A (ko) | 2022-05-03 | 2023-11-14 | 한국생명공학연구원 | 신규 펩타이드 및 이의 항염 및 재생 용도 |
| KR20240086709A (ko) * | 2022-11-18 | 2024-06-19 | (주)케어젠 | 피부 상태 개선 활성을 갖는 펩타이드 및 이의 용도 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL97428A0 (en) * | 1990-03-05 | 1992-06-21 | Cephalon Inc | Chymotrypsin-like proteases and their inhibitors |
| FR2814076B1 (fr) * | 2000-09-21 | 2002-12-20 | Centre Nat Rech Scient | Agent angiogenique et ses utilisations |
| WO2007026356A2 (en) * | 2005-08-29 | 2007-03-08 | Healor Ltd. | Methods and compositions for prevention and treatment of diabetic and aged skin |
| CN101472944B (zh) * | 2006-06-13 | 2014-05-28 | 赫里克斯生物医疗公司 | 用于诱导细胞外基质蛋白合成的肽片段 |
| JP2007001981A (ja) * | 2006-07-10 | 2007-01-11 | Nippon Meat Packers Inc | 皮膚組織の再生及び肌質改善効果のあるペプチドを含有する化粧品 |
| CN101679495B (zh) * | 2007-01-05 | 2013-07-17 | 赫里克斯生物医疗公司 | 用于细胞学和免疫学调节的短的生物活性肽 |
| PL2205623T3 (pl) | 2007-10-29 | 2016-09-30 | Ochronne tetrapeptydy do pielęgnacji skóry | |
| EP2109054A1 (en) * | 2008-04-09 | 2009-10-14 | Biotempt B.V. | Methods for identifying biologically active peptides and predicting their function |
| TWI429451B (zh) * | 2011-10-26 | 2014-03-11 | Nat Univ Tsing Hua | 對具有ｅｌｒ－ｃｘｃ趨化素高度親和力的受體蛋白細胞所引發疾病之拮抗治療劑 |
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2014
- 2014-05-14 CN CN201480033362.9A patent/CN105324122B/zh active Active
- 2014-05-14 HU HUE14730697A patent/HUE032970T2/en unknown
- 2014-05-14 SG SG11201509048VA patent/SG11201509048VA/en unknown
- 2014-05-14 CA CA2915174A patent/CA2915174C/en active Active
- 2014-05-14 PL PL14730697T patent/PL3007716T3/pl unknown
- 2014-05-14 EP EP14730697.1A patent/EP3007716B1/en active Active
- 2014-05-14 DK DK14730697.1T patent/DK3007716T3/da active
- 2014-05-14 WO PCT/US2014/037978 patent/WO2014200651A1/en active Application Filing
- 2014-05-14 JP JP2016519511A patent/JP6416240B2/ja active Active
- 2014-05-14 SI SI201430262T patent/SI3007716T1/sl unknown
- 2014-05-14 KR KR1020157037042A patent/KR102254260B1/ko active IP Right Grant
- 2014-05-14 AU AU2014278708A patent/AU2014278708B2/en active Active
- 2014-05-14 MX MX2015017089A patent/MX362846B/es active IP Right Grant
- 2014-05-14 BR BR112015031018-4A patent/BR112015031018B1/pt active IP Right Grant
- 2014-05-14 US US14/907,811 patent/US10195245B2/en active Active
- 2014-05-14 MY MYPI2015704511A patent/MY168981A/en unknown
- 2014-05-14 ES ES14730697.1T patent/ES2631804T3/es active Active
- 2014-05-14 RU RU2015146679A patent/RU2687151C2/ru active
- 2014-06-12 TW TW103120387A patent/TWI511737B/zh active
- 2014-06-12 AR ARP140102248A patent/AR096594A1/es not_active Application Discontinuation
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2016
- 2016-05-12 HK HK16105420.1A patent/HK1217436A1/zh unknown
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2017
- 2017-06-22 CY CY20171100663T patent/CY1119191T1/el unknown
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