BR112015031018A2 - tetrapeptídeo isolado, composição e composição para uso - Google Patents
tetrapeptídeo isolado, composição e composição para usoInfo
- Publication number
- BR112015031018A2 BR112015031018A2 BR112015031018A BR112015031018A BR112015031018A2 BR 112015031018 A2 BR112015031018 A2 BR 112015031018A2 BR 112015031018 A BR112015031018 A BR 112015031018A BR 112015031018 A BR112015031018 A BR 112015031018A BR 112015031018 A2 BR112015031018 A2 BR 112015031018A2
- Authority
- BR
- Brazil
- Prior art keywords
- skin
- psoriasis
- removal
- composition
- bioactivities
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
- A61Q7/02—Preparations for inhibiting or slowing hair growth
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Birds (AREA)
- Toxicology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Abstract
tetrapeptídeos que consistem em (i ou v)-x1-k-x2, onde x1 pode ser selecionado a partir de e, q ou k, e x2 pode ser selecionado a partir de m, f, i, w, ou v, exibem diversas bioatividades. eles são moléculas efetoras multifuncionais para estimular a migração de queratinócitos; neutralizar o efeito pró-inflamatório dos componentes da parede celular bacteriana, tais como ácidos lipoteicoicos de bactérias gram-positivas s. aureus; e induzir angiogênese em células endoteliais da veia umbilical humana em cultura. a down-regulação da condição pró-inflamatória também foi demonstrada usando modelo de pele com psoríase sor-300-ft para o peptídeo representativo. a bioatividade também foi comprovada pelo estudo de perfilagem genética sobre o tratamento de tecidos de pele normais usando substitutos de pele epidermtm. os peptídeos da invenção com diversas bioatividades são úteis para o tratamento de várias condições da pele incluindo, mas não limitadas a, feridas agudas ou crônicas, estrias de distensão, envelhecimento da pele, controle de pelos, peles em inflamação, tais como psoríase, dermatite atópica e rosácea, e para a remoção de pelos indesejados ou para condições tais como a remoção de pólipos fibroepiteliais.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361835424P | 2013-06-14 | 2013-06-14 | |
| US61/835,424 | 2013-06-14 | ||
| PCT/US2014/037978 WO2014200651A1 (en) | 2013-06-14 | 2014-05-14 | Tetrapeptides derived from human c-x-c chemokines useful for treatment of various skin conditions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112015031018A2 true BR112015031018A2 (pt) | 2018-09-25 |
| BR112015031018B1 BR112015031018B1 (pt) | 2023-03-07 |
Family
ID=50943603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112015031018-4A BR112015031018B1 (pt) | 2013-06-14 | 2014-05-14 | Composição compreendendo um tetrapeptídeo para tratamento de condições da pele |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US10195245B2 (pt) |
| EP (1) | EP3007716B1 (pt) |
| JP (1) | JP6416240B2 (pt) |
| KR (1) | KR102254260B1 (pt) |
| CN (1) | CN105324122B (pt) |
| AR (1) | AR096594A1 (pt) |
| AU (1) | AU2014278708B2 (pt) |
| BR (1) | BR112015031018B1 (pt) |
| CA (1) | CA2915174C (pt) |
| CY (1) | CY1119191T1 (pt) |
| DK (1) | DK3007716T3 (pt) |
| ES (1) | ES2631804T3 (pt) |
| HK (1) | HK1217436A1 (pt) |
| HU (1) | HUE032970T2 (pt) |
| MX (1) | MX362846B (pt) |
| MY (1) | MY168981A (pt) |
| PL (1) | PL3007716T3 (pt) |
| RU (1) | RU2687151C2 (pt) |
| SG (1) | SG11201509048VA (pt) |
| SI (1) | SI3007716T1 (pt) |
| TW (1) | TWI511737B (pt) |
| WO (1) | WO2014200651A1 (pt) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110302088A (zh) * | 2019-04-29 | 2019-10-08 | 杭州肽佳生物科技有限公司 | 一种包含修饰芋螺肽的化妆品组合物 |
| EP4093369A1 (en) * | 2020-01-21 | 2022-11-30 | ASC Regenity Ltd. | Cosmetic formulation for topical administration comprising novel peptides that improve appearance and regeneration of skin |
| EP3925626A1 (en) | 2020-03-06 | 2021-12-22 | Gdanski Uniwersytet Medyczny | Lipopeptide conjugates and their salts, method of manufacture of lipopeptide conjugates and their salts, pharmaceutical composition comprising a lipopeptide conjugate and its salts for the treatment of chronic wounds |
| WO2022098051A1 (ko) | 2020-11-05 | 2022-05-12 | 한국생명공학연구원 | 항염 및 조직 재생작용을 갖는 신규 펩타이드 |
| CN113698452B (zh) * | 2021-08-23 | 2023-08-18 | 四川丽妍工坊生物科技有限公司 | 一种促皮肤修复肽、制备方法及其应用 |
| WO2023080790A1 (en) * | 2021-11-02 | 2023-05-11 | Tosoj As | Tri-, tetra and pentapeptides, compositions thereof and their use in the therapy of psoriasis |
| WO2023214802A1 (ko) * | 2022-05-03 | 2023-11-09 | 한국생명공학연구원 | 신규 펩타이드 및 이의 항염 및 재생 용도 |
| WO2024106587A1 (ko) * | 2022-11-18 | 2024-05-23 | (주)케어젠 | 피부 상태 개선 활성을 갖는 펩타이드 및 이의 용도 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU661270B2 (en) * | 1990-03-05 | 1995-07-20 | Cephalon, Inc. | Chymotrypsin-like proteases and their inhibitors |
| FR2814076B1 (fr) | 2000-09-21 | 2002-12-20 | Centre Nat Rech Scient | Agent angiogenique et ses utilisations |
| AU2006286152B2 (en) | 2005-08-29 | 2012-05-31 | Healor Ltd. | Methods and compositions for prevention and treatment of diabetic and aged skin |
| SI2409988T1 (sl) | 2006-06-13 | 2015-10-30 | Helix Biomedix Inc. | Peptidni fragmenti za sprožitev sinteze proteinov zunajcelične matrice |
| JP2007001981A (ja) | 2006-07-10 | 2007-01-11 | Nippon Meat Packers Inc | 皮膚組織の再生及び肌質改善効果のあるペプチドを含有する化粧品 |
| WO2008085494A1 (en) | 2007-01-05 | 2008-07-17 | Helix Biomedix Inc. | Short bio-active peptides for cellular and immunological modulation |
| US8071555B2 (en) | 2007-10-29 | 2011-12-06 | Helix Biomedix Inc. | Protective skin care peptides |
| EP2109054A1 (en) | 2008-04-09 | 2009-10-14 | Biotempt B.V. | Methods for identifying biologically active peptides and predicting their function |
| TWI429451B (zh) * | 2011-10-26 | 2014-03-11 | Nat Univ Tsing Hua | 對具有ｅｌｒ－ｃｘｃ趨化素高度親和力的受體蛋白細胞所引發疾病之拮抗治療劑 |
-
2014
- 2014-05-14 RU RU2015146679A patent/RU2687151C2/ru active
- 2014-05-14 BR BR112015031018-4A patent/BR112015031018B1/pt active IP Right Grant
- 2014-05-14 CA CA2915174A patent/CA2915174C/en active Active
- 2014-05-14 MX MX2015017089A patent/MX362846B/es active IP Right Grant
- 2014-05-14 AU AU2014278708A patent/AU2014278708B2/en active Active
- 2014-05-14 JP JP2016519511A patent/JP6416240B2/ja active Active
- 2014-05-14 SG SG11201509048VA patent/SG11201509048VA/en unknown
- 2014-05-14 ES ES14730697.1T patent/ES2631804T3/es active Active
- 2014-05-14 KR KR1020157037042A patent/KR102254260B1/ko active IP Right Grant
- 2014-05-14 MY MYPI2015704511A patent/MY168981A/en unknown
- 2014-05-14 WO PCT/US2014/037978 patent/WO2014200651A1/en active Application Filing
- 2014-05-14 US US14/907,811 patent/US10195245B2/en active Active
- 2014-05-14 SI SI201430262T patent/SI3007716T1/sl unknown
- 2014-05-14 EP EP14730697.1A patent/EP3007716B1/en active Active
- 2014-05-14 PL PL14730697T patent/PL3007716T3/pl unknown
- 2014-05-14 HU HUE14730697A patent/HUE032970T2/en unknown
- 2014-05-14 CN CN201480033362.9A patent/CN105324122B/zh active Active
- 2014-05-14 DK DK14730697.1T patent/DK3007716T3/en active
- 2014-06-12 AR ARP140102248A patent/AR096594A1/es not_active Application Discontinuation
- 2014-06-12 TW TW103120387A patent/TWI511737B/zh active
-
2016
- 2016-05-12 HK HK16105420.1A patent/HK1217436A1/zh unknown
-
2017
- 2017-06-22 CY CY20171100663T patent/CY1119191T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NAO 10196/2001, QUE MODIFICOU A LEI NAO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUAANCIA PRA VIA DA ANVISA. CONSIDERANDO A APROVAA AO DOS TERMOS DO PARECER NAO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NAO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDAANCIAS CABA-VEIS. |
|
| B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
| B06U | Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette] | ||
| B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
| B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
| B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 14/05/2014, OBSERVADAS AS CONDICOES LEGAIS |