AR096594A1 - Tetrapéptidos derivados de quimioquinas c-x-c humanas útiles para tratar diversas afecciones en la piel - Google Patents
Tetrapéptidos derivados de quimioquinas c-x-c humanas útiles para tratar diversas afecciones en la pielInfo
- Publication number
- AR096594A1 AR096594A1 ARP140102248A ARP140102248A AR096594A1 AR 096594 A1 AR096594 A1 AR 096594A1 AR P140102248 A ARP140102248 A AR P140102248A AR P140102248 A ARP140102248 A AR P140102248A AR 096594 A1 AR096594 A1 AR 096594A1
- Authority
- AR
- Argentina
- Prior art keywords
- useful
- skin
- inflammation
- chemiokins
- hair
- Prior art date
Links
- 210000003491 skin Anatomy 0.000 abstract 4
- 230000004071 biological effect Effects 0.000 abstract 3
- 206010061218 Inflammation Diseases 0.000 abstract 2
- 201000004681 Psoriasis Diseases 0.000 abstract 2
- 230000004054 inflammatory process Effects 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 206010012438 Dermatitis atopic Diseases 0.000 abstract 1
- 241001303601 Rosacea Species 0.000 abstract 1
- 206010040925 Skin striae Diseases 0.000 abstract 1
- 208000031439 Striae Distensae Diseases 0.000 abstract 1
- 206010052428 Wound Diseases 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 230000001154 acute effect Effects 0.000 abstract 1
- 230000032683 aging Effects 0.000 abstract 1
- 230000033115 angiogenesis Effects 0.000 abstract 1
- 201000008937 atopic dermatitis Diseases 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 230000006866 deterioration Effects 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 210000003038 endothelium Anatomy 0.000 abstract 1
- 210000002510 keratinocyte Anatomy 0.000 abstract 1
- 230000005012 migration Effects 0.000 abstract 1
- 238000013508 migration Methods 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 230000000770 proinflammatory effect Effects 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 201000004700 rosacea Diseases 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 abstract 1
- 210000003606 umbilical vein Anatomy 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
- A61Q7/02—Preparations for inhibiting or slowing hair growth
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Birds (AREA)
- Toxicology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Pulmonology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
Abstract
Tetrapéptidos que consisten en la secuencia (I o V)-X¹-K-X², donde X¹ puede seleccionarse entre E, Q o K y X² puede seleccionarse entre M, F, l, W o V, que presentan actividades biológicas diversas: pueden ser útiles para estimular la migración de los queratinocitos, para neutralizar el efecto proinflamatorio propio de determinados componentes de la pared de las bacterias, tales como los ácidos lipoteicoicos de las bacterias Gram positivas S. aureus, o para inducir la angiogenésis en las células provenientes del endotelio de la vena umbilical humana en cultivo. Mediante el uso de un modelo de la psoriasis basado en el un tejido SOR-300-FT, también se ha demostrado que un péptido representativo fue útil para combatir diversas afecciones relacionadas con la inflamación. Por otro lado, la actividad biológica se analizó en función del perfil de diversos genes, en el contexto de un tratamiento sobre sustitutos de piel EPIDERMTM. Los péptidos de acuerdo con la presente, que presentan actividades biológicas diversas, pueden resultar útiles para tratar una variedad de afecciones en la piel, entre las que pueden mencionarse a modo de ejemplos no limitativos las heridas agudas o crónicas, las estrías, los efectos del envejecimiento, el deterioro del cabello y las afecciones relacionadas con la inflamación, tales como la psoriasis o la dermatitis atópica o la rosácea, así como para remover el cabello indeseable o las marcas en la piel.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361835424P | 2013-06-14 | 2013-06-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR096594A1 true AR096594A1 (es) | 2016-01-20 |
Family
ID=50943603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP140102248A AR096594A1 (es) | 2013-06-14 | 2014-06-12 | Tetrapéptidos derivados de quimioquinas c-x-c humanas útiles para tratar diversas afecciones en la piel |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US10195245B2 (es) |
| EP (1) | EP3007716B1 (es) |
| JP (1) | JP6416240B2 (es) |
| KR (1) | KR102254260B1 (es) |
| CN (1) | CN105324122B (es) |
| AR (1) | AR096594A1 (es) |
| AU (1) | AU2014278708B2 (es) |
| BR (1) | BR112015031018B1 (es) |
| CA (1) | CA2915174C (es) |
| CY (1) | CY1119191T1 (es) |
| DK (1) | DK3007716T3 (es) |
| ES (1) | ES2631804T3 (es) |
| HK (1) | HK1217436A1 (es) |
| HU (1) | HUE032970T2 (es) |
| MX (1) | MX362846B (es) |
| MY (1) | MY168981A (es) |
| PL (1) | PL3007716T3 (es) |
| RU (1) | RU2687151C2 (es) |
| SG (1) | SG11201509048VA (es) |
| SI (1) | SI3007716T1 (es) |
| TW (1) | TWI511737B (es) |
| WO (1) | WO2014200651A1 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110302088A (zh) * | 2019-04-29 | 2019-10-08 | 杭州肽佳生物科技有限公司 | 一种包含修饰芋螺肽的化妆品组合物 |
| EP4093369A1 (en) * | 2020-01-21 | 2022-11-30 | ASC Regenity Ltd. | Cosmetic formulation for topical administration comprising novel peptides that improve appearance and regeneration of skin |
| EP3925626A1 (en) | 2020-03-06 | 2021-12-22 | Gdanski Uniwersytet Medyczny | Lipopeptide conjugates and their salts, method of manufacture of lipopeptide conjugates and their salts, pharmaceutical composition comprising a lipopeptide conjugate and its salts for the treatment of chronic wounds |
| KR20220061018A (ko) | 2020-11-05 | 2022-05-12 | 한국생명공학연구원 | 항염 및 조직 재생작용을 갖는 신규 펩타이드 |
| CN113698452B (zh) * | 2021-08-23 | 2023-08-18 | 四川丽妍工坊生物科技有限公司 | 一种促皮肤修复肽、制备方法及其应用 |
| CA3233983A1 (en) * | 2021-11-02 | 2023-05-11 | Ole-Jan Iversen (Deceased) | Tri-, tetra and pentapeptides, compositions thereof and their use in the therapy of psoriasis |
| KR20230156265A (ko) | 2022-05-03 | 2023-11-14 | 한국생명공학연구원 | 신규 펩타이드 및 이의 항염 및 재생 용도 |
| WO2024106587A1 (ko) * | 2022-11-18 | 2024-05-23 | (주)케어젠 | 피부 상태 개선 활성을 갖는 펩타이드 및 이의 용도 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991013904A1 (en) * | 1990-03-05 | 1991-09-19 | Cephalon, Inc. | Chymotrypsin-like proteases and their inhibitors |
| FR2814076B1 (fr) | 2000-09-21 | 2002-12-20 | Centre Nat Rech Scient | Agent angiogenique et ses utilisations |
| WO2007026356A2 (en) | 2005-08-29 | 2007-03-08 | Healor Ltd. | Methods and compositions for prevention and treatment of diabetic and aged skin |
| BRPI0713153B8 (pt) | 2006-06-13 | 2021-05-25 | Helix Biomedix Inc | tetrapeptídeo capaz de induzir a produção das proteínas da matriz extracelular e composição o compreendendo |
| JP2007001981A (ja) | 2006-07-10 | 2007-01-11 | Nippon Meat Packers Inc | 皮膚組織の再生及び肌質改善効果のあるペプチドを含有する化粧品 |
| ES2404669T3 (es) | 2007-01-05 | 2013-05-28 | Helix Biomedix, Inc. | Péptidos bioactivos cortos para modulación celular e inmunológica |
| CN101855235B (zh) | 2007-10-29 | 2013-04-24 | 赫里克斯生物医疗公司 | 保护性皮肤护理四肽 |
| EP2109054A1 (en) * | 2008-04-09 | 2009-10-14 | Biotempt B.V. | Methods for identifying biologically active peptides and predicting their function |
| TWI429451B (zh) | 2011-10-26 | 2014-03-11 | Nat Univ Tsing Hua | 對具有ｅｌｒ－ｃｘｃ趨化素高度親和力的受體蛋白細胞所引發疾病之拮抗治療劑 |
-
2014
- 2014-05-14 SI SI201430262T patent/SI3007716T1/sl unknown
- 2014-05-14 JP JP2016519511A patent/JP6416240B2/ja active Active
- 2014-05-14 CA CA2915174A patent/CA2915174C/en active Active
- 2014-05-14 AU AU2014278708A patent/AU2014278708B2/en active Active
- 2014-05-14 PL PL14730697T patent/PL3007716T3/pl unknown
- 2014-05-14 WO PCT/US2014/037978 patent/WO2014200651A1/en active Application Filing
- 2014-05-14 EP EP14730697.1A patent/EP3007716B1/en active Active
- 2014-05-14 BR BR112015031018-4A patent/BR112015031018B1/pt active IP Right Grant
- 2014-05-14 RU RU2015146679A patent/RU2687151C2/ru active
- 2014-05-14 CN CN201480033362.9A patent/CN105324122B/zh active Active
- 2014-05-14 DK DK14730697.1T patent/DK3007716T3/en active
- 2014-05-14 HU HUE14730697A patent/HUE032970T2/en unknown
- 2014-05-14 KR KR1020157037042A patent/KR102254260B1/ko active IP Right Grant
- 2014-05-14 US US14/907,811 patent/US10195245B2/en active Active
- 2014-05-14 MY MYPI2015704511A patent/MY168981A/en unknown
- 2014-05-14 ES ES14730697.1T patent/ES2631804T3/es active Active
- 2014-05-14 MX MX2015017089A patent/MX362846B/es active IP Right Grant
- 2014-05-14 SG SG11201509048VA patent/SG11201509048VA/en unknown
- 2014-06-12 AR ARP140102248A patent/AR096594A1/es not_active Application Discontinuation
- 2014-06-12 TW TW103120387A patent/TWI511737B/zh active
-
2016
- 2016-05-12 HK HK16105420.1A patent/HK1217436A1/zh unknown
-
2017
- 2017-06-22 CY CY20171100663T patent/CY1119191T1/el unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |