DK2886123T3 - Pluripotent stamcelle som inducerer reparation og regeneration efter myokardieinfarkt - Google Patents
Pluripotent stamcelle som inducerer reparation og regeneration efter myokardieinfarkt Download PDFInfo
- Publication number
- DK2886123T3 DK2886123T3 DK13879518.2T DK13879518T DK2886123T3 DK 2886123 T3 DK2886123 T3 DK 2886123T3 DK 13879518 T DK13879518 T DK 13879518T DK 2886123 T3 DK2886123 T3 DK 2886123T3
- Authority
- DK
- Denmark
- Prior art keywords
- incarf
- myocardia
- regeneration
- stem cells
- pluripotent stem
- Prior art date
Links
- 230000001939 inductive effect Effects 0.000 title 1
- 210000004165 myocardium Anatomy 0.000 title 1
- 210000001778 pluripotent stem cell Anatomy 0.000 title 1
- 230000008929 regeneration Effects 0.000 title 1
- 238000011069 regeneration method Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0607—Non-embryonic pluripotent stem cells, e.g. MASC
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
- C12N2506/03—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from non-embryonic pluripotent stem cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012181029 | 2012-08-17 | ||
| PCT/JP2013/054049 WO2014027474A1 (ja) | 2012-08-17 | 2013-02-19 | 心筋梗塞の修復再生を誘導する多能性幹細胞 |
| PCT/JP2013/071981 WO2014027684A1 (ja) | 2012-08-17 | 2013-08-15 | 心筋梗塞の修復再生を誘導する多能性幹細胞 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2886123T3 true DK2886123T3 (da) | 2020-01-27 |
Family
ID=50685515
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13879518.2T DK2886123T3 (da) | 2012-08-17 | 2013-08-15 | Pluripotent stamcelle som inducerer reparation og regeneration efter myokardieinfarkt |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US9844570B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2886123B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP5968442B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR101730052B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN104582711B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2013303492B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2882239C (cg-RX-API-DMAC7.html) |
| DK (1) | DK2886123T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2767182T3 (cg-RX-API-DMAC7.html) |
| IN (1) | IN2015DN01616A (cg-RX-API-DMAC7.html) |
| PL (1) | PL2886123T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT2886123T (cg-RX-API-DMAC7.html) |
| SG (2) | SG10201800829XA (cg-RX-API-DMAC7.html) |
| WO (2) | WO2014027474A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014027474A1 (ja) | 2012-08-17 | 2014-02-20 | 株式会社Ｃｌｉｏ | 心筋梗塞の修復再生を誘導する多能性幹細胞 |
| JP2015160820A (ja) * | 2014-02-26 | 2015-09-07 | 株式会社Ｃｌｉｏ | 慢性腎障害治療のための多能性幹細胞 |
| JP6452107B2 (ja) | 2014-09-05 | 2019-01-16 | 国立大学法人 東京大学 | 糖尿病性皮膚潰瘍治療のための多能性幹細胞 |
| WO2016168993A1 (en) * | 2015-04-22 | 2016-10-27 | Innolife Co., Ltd. | Methods of tissue repair and regeneration |
| JP6770673B2 (ja) * | 2016-02-26 | 2020-10-21 | 国立大学法人東海国立大学機構 | 急性心筋梗塞の予後マーカー及びその利用 |
| SG11201811806TA (en) * | 2016-07-01 | 2019-02-27 | Univ Tohoku | Prophylactic or therapeutic agent for organ fibrosis |
| CA3032358A1 (en) * | 2016-07-29 | 2018-02-01 | Tohoku University | Prophylactic or therapeutic agent for vascular disorder |
| SG11201900989QA (en) | 2016-08-03 | 2019-03-28 | Life Science Institute Inc | Method for inducing differentiation of pluripotent stem cells in vitro |
| WO2018025976A1 (ja) * | 2016-08-03 | 2018-02-08 | 株式会社生命科学インスティテュート | 多能性幹細胞による虚血再灌流肺障害の軽減及び治療 |
| KR102503101B1 (ko) * | 2016-08-03 | 2023-02-23 | 고쿠리츠 다이가쿠 호우징 도우카이 고쿠리츠 다이가쿠 기코우 | 다능성 간세포에 따른 만성폐질환의 개선 및 치료 |
| CN106822899B (zh) * | 2017-03-10 | 2020-11-27 | 北京大学 | 一种通过抑制自噬促进心肌再生的药物 |
| KR20200070247A (ko) * | 2017-10-17 | 2020-06-17 | 고쿠리츠다이가쿠호진 히로시마다이가쿠 | 골연골 수복을 유도하는 다능성 간세포 |
| JP7102666B2 (ja) * | 2018-01-25 | 2022-07-20 | 国立大学法人東海国立大学機構 | Ｍｕｓｅ細胞動員剤及び心筋障害への利用 |
| JP7072777B2 (ja) * | 2018-07-03 | 2022-05-23 | 株式会社生命科学インスティテュート | 慢性腎障害治療のための多能性幹細胞 |
| CN110302212A (zh) * | 2019-07-17 | 2019-10-08 | 陶正博 | 一种用于治疗急性心肌梗死的细胞制剂及其制备方法 |
| US12460182B2 (en) | 2019-08-19 | 2025-11-04 | Cellaxia Inc. | Cell-containing pharmaceutical composition |
| WO2021045190A1 (ja) * | 2019-09-05 | 2021-03-11 | 国立大学法人東北大学 | 心筋炎の治療剤 |
| WO2021085639A1 (ja) * | 2019-10-31 | 2021-05-06 | 株式会社生命科学インスティテュート | 多能性幹細胞による間質性膀胱炎の治療 |
| CN115843311A (zh) | 2020-04-02 | 2023-03-24 | 国立大学法人东北大学 | 高潜能多能干细胞 |
| TWI825446B (zh) * | 2020-08-14 | 2023-12-11 | 中國醫藥大學 | 醫藥組合物治療組織缺血狀況之用途 |
| JP2021073305A (ja) * | 2021-02-09 | 2021-05-13 | 株式会社生命科学インスティテュート | 慢性腎障害治療のための多能性幹細胞 |
| CN119198334A (zh) * | 2024-10-31 | 2024-12-27 | 北京大学深圳研究生院 | 一种心肌梗死边界区组织鉴定方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4543193A (en) * | 1992-06-22 | 1994-01-24 | Henry E. Young | Scar inhibitory factor and use thereof |
| ATE307195T1 (de) * | 1997-07-14 | 2005-11-15 | Osiris Therapeutics Inc | Herzmuskelregenerierung unter verwendung mesenchymaler stammzellen |
| ATE382681T1 (de) * | 1998-07-31 | 2008-01-15 | Genzyme Corp | Verbesserung der herzfunktion durch transplantation mesenchymaler stammzellen |
| US20020061587A1 (en) | 2000-07-31 | 2002-05-23 | Piero Anversa | Methods and compositions for the repair and/or regeneration of damaged myocardium |
| CA2434362A1 (en) * | 2001-01-20 | 2002-07-25 | Cardion Ag | Pluripotent adult stem cells derived from regenerative tissue |
| KR101073411B1 (ko) | 2001-07-12 | 2011-10-17 | 제론 코포레이션 | 인간 다분화능 줄기 세포로부터 제조된 심근 세포 계통의 세포 |
| WO2006080434A1 (ja) | 2005-01-27 | 2006-08-03 | Japan Health Sciences Foundation | 間葉系幹細胞を含む細胞シート |
| CN101864392B (zh) | 2005-12-13 | 2016-03-23 | 国立大学法人京都大学 | 核重新编程因子 |
| CN101517069A (zh) * | 2006-07-13 | 2009-08-26 | 塞拉帝思股份公司 | 由人类胚泡来源的干细胞衍生的多能心脏前体细胞新种群 |
| EP2205251B1 (en) * | 2007-10-01 | 2017-01-11 | University of Miami | A method to amplify cardiac stem cells in vitro and in vivo |
| JP5394932B2 (ja) * | 2007-11-02 | 2014-01-22 | 日本ケミカルリサーチ株式会社 | ヒト間葉系幹細胞含有医薬組成物 |
| JP5564679B2 (ja) | 2009-04-16 | 2014-07-30 | 公益財団法人ヒューマンサイエンス振興財団 | 心筋細胞分化誘導促進剤およびその使用方法 |
| US9550975B2 (en) * | 2009-07-15 | 2017-01-24 | Mari Dezawa | SSEA-3 pluripotent stem cell isolated from body tissue |
| AU2011317203B2 (en) * | 2010-10-18 | 2016-10-20 | Sunshine Life Science & Technology Corp. | Human multipotent embryonic stem cell-like progenitor cells |
| WO2014027474A1 (ja) | 2012-08-17 | 2014-02-20 | 株式会社Ｃｌｉｏ | 心筋梗塞の修復再生を誘導する多能性幹細胞 |
-
2013
- 2013-02-19 WO PCT/JP2013/054049 patent/WO2014027474A1/ja not_active Ceased
- 2013-08-15 KR KR1020157006629A patent/KR101730052B1/ko not_active Expired - Fee Related
- 2013-08-15 DK DK13879518.2T patent/DK2886123T3/da active
- 2013-08-15 PT PT138795182T patent/PT2886123T/pt unknown
- 2013-08-15 IN IN1616DEN2015 patent/IN2015DN01616A/en unknown
- 2013-08-15 EP EP13879518.2A patent/EP2886123B1/en active Active
- 2013-08-15 PL PL13879518T patent/PL2886123T3/pl unknown
- 2013-08-15 AU AU2013303492A patent/AU2013303492B2/en not_active Ceased
- 2013-08-15 JP JP2014530568A patent/JP5968442B2/ja active Active
- 2013-08-15 SG SG10201800829XA patent/SG10201800829XA/en unknown
- 2013-08-15 WO PCT/JP2013/071981 patent/WO2014027684A1/ja not_active Ceased
- 2013-08-15 EP EP19202650.8A patent/EP3659612B1/en active Active
- 2013-08-15 US US14/421,754 patent/US9844570B2/en active Active
- 2013-08-15 CA CA2882239A patent/CA2882239C/en active Active
- 2013-08-15 SG SG11201501185WA patent/SG11201501185WA/en unknown
- 2013-08-15 CN CN201380043649.5A patent/CN104582711B/zh active Active
- 2013-08-15 ES ES13879518T patent/ES2767182T3/es active Active
-
2017
- 2017-11-03 US US15/802,899 patent/US10376544B2/en active Active
-
2019
- 2019-06-25 US US16/452,376 patent/US10639335B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| SG10201800829XA (en) | 2018-03-28 |
| EP2886123B1 (en) | 2019-10-23 |
| US20190307806A1 (en) | 2019-10-10 |
| JPWO2014027684A1 (ja) | 2016-07-28 |
| KR20150043482A (ko) | 2015-04-22 |
| AU2013303492A1 (en) | 2015-03-12 |
| SG11201501185WA (en) | 2015-05-28 |
| US20150196600A1 (en) | 2015-07-16 |
| US9844570B2 (en) | 2017-12-19 |
| IN2015DN01616A (cg-RX-API-DMAC7.html) | 2015-07-03 |
| JP5968442B2 (ja) | 2016-08-10 |
| ES2767182T3 (es) | 2020-06-16 |
| WO2014027684A1 (ja) | 2014-02-20 |
| US10376544B2 (en) | 2019-08-13 |
| CA2882239C (en) | 2018-05-22 |
| CA2882239A1 (en) | 2014-02-20 |
| EP3659612B1 (en) | 2023-06-07 |
| PT2886123T (pt) | 2020-01-22 |
| EP2886123A1 (en) | 2015-06-24 |
| US10639335B2 (en) | 2020-05-05 |
| EP3659612A1 (en) | 2020-06-03 |
| KR101730052B1 (ko) | 2017-04-25 |
| US20180050067A1 (en) | 2018-02-22 |
| WO2014027474A1 (ja) | 2014-02-20 |
| CN104582711B (zh) | 2019-12-06 |
| AU2013303492B2 (en) | 2017-02-16 |
| EP2886123A4 (en) | 2016-06-22 |
| CN104582711A (zh) | 2015-04-29 |
| PL2886123T3 (pl) | 2020-05-18 |
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