DK2806022T3 - Recombinant microorganism with improved putrescine productivity and method of producing putrescine using the same - Google Patents
Recombinant microorganism with improved putrescine productivity and method of producing putrescine using the same Download PDFInfo
- Publication number
- DK2806022T3 DK2806022T3 DK13738280.0T DK13738280T DK2806022T3 DK 2806022 T3 DK2806022 T3 DK 2806022T3 DK 13738280 T DK13738280 T DK 13738280T DK 2806022 T3 DK2806022 T3 DK 2806022T3
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- DK
- Denmark
- Prior art keywords
- ala
- leu
- val
- gly
- glu
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- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 description 1
- 229960000344 thiamine hydrochloride Drugs 0.000 description 1
- 235000019190 thiamine hydrochloride Nutrition 0.000 description 1
- 239000011747 thiamine hydrochloride Substances 0.000 description 1
- 108010033670 threonyl-aspartyl-tyrosine Proteins 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 230000005030 transcription termination Effects 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 108010080629 tryptophan-leucine Proteins 0.000 description 1
- 108010015666 tryptophyl-leucyl-glutamic acid Proteins 0.000 description 1
- 108010017949 tyrosyl-glycyl-glycine Proteins 0.000 description 1
- 241001515965 unidentified phage Species 0.000 description 1
- IBIDRSSEHFLGSD-UHFFFAOYSA-N valinyl-arginine Natural products CC(C)C(N)C(=O)NC(C(O)=O)CCCN=C(N)N IBIDRSSEHFLGSD-UHFFFAOYSA-N 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 108010027345 wheylin-1 peptide Proteins 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/001—Amines; Imines
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/15—Corynebacterium
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20120007004 | 2012-01-20 | ||
PCT/KR2013/000487 WO2013109121A1 (ko) | 2012-01-20 | 2013-01-21 | 퓨트레신 생산능이 향상된 재조합 미생물 및 이를 이용하여 퓨트레신을 생산하는 방법 |
Publications (1)
Publication Number | Publication Date |
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DK2806022T3 true DK2806022T3 (en) | 2018-08-13 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK13738280.0T DK2806022T3 (en) | 2012-01-20 | 2013-01-21 | Recombinant microorganism with improved putrescine productivity and method of producing putrescine using the same |
Country Status (14)
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
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KR101607741B1 (ko) * | 2013-03-20 | 2016-03-31 | 씨제이제일제당 (주) | 퓨트레신 생산 재조합 미생물 및 이를 이용한 퓨트레신 생산방법 |
JP6526792B2 (ja) | 2014-04-25 | 2019-06-05 | シージェイ チェイルジェダン コーポレーション | プトレシンを生産する微生物及びそれらを用いてプトレシンを生産する方法 |
KR101773135B1 (ko) * | 2015-05-08 | 2017-08-30 | 씨제이제일제당 주식회사 | 1,4-디아미노부탄의 정제방법 |
US12139733B2 (en) | 2018-12-27 | 2024-11-12 | Cj Cheiljedang Corporation | Ornithine decarboxylase variant and method for producing putrescine by using same |
WO2020138543A1 (ko) * | 2018-12-27 | 2020-07-02 | 씨제이제일제당 (주) | 오르니틴 탈탄산 효소의 변이주 및 그의 응용 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
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KR920007401B1 (ko) | 1990-06-21 | 1992-08-31 | 제일제당 주식회사 | 다발성 절단부위를 지닌 대장균과 코리네형 세균에서 발현 가능한 신규 셔틀벡터 |
ES2581244T3 (es) * | 2004-07-15 | 2016-09-02 | Dsm Ip Assets B.V. | Síntesis bioquímica de 1,4-butanodiamina |
KR100620092B1 (ko) | 2004-12-16 | 2006-09-08 | 씨제이 주식회사 | 코리네박테리움 속 세포로부터 유래된 신규한 프로모터서열, 그를 포함하는 발현 카세트 및 벡터, 상기 벡터를포함하는 숙주 세포 및 그를 이용하여 유전자를 발현하는방법 |
EP2067235A4 (en) | 2006-09-30 | 2010-03-10 | Osram Gmbh | POWER SUPPLY AND ELECTRONIC BALLAST WITH AUXILIARY PROTECTION CIRCUIT |
KR100860932B1 (ko) | 2007-02-08 | 2008-09-29 | 씨제이제일제당 (주) | 신규한 프로모터 및 이의 용도 |
KR101188432B1 (ko) * | 2008-04-10 | 2012-10-08 | 한국과학기술원 | 퓨트레신 고생성능을 가지는 변이 미생물 및 이를 이용한 퓨트레신의 제조방법 |
AU2009234625B2 (en) | 2008-04-10 | 2012-07-19 | Korea Advanced Institute Of Science And Technology | Mutant microorganisms having high ability to produce putrescine and method for producing putrescine using the same |
KR101348461B1 (ko) | 2010-12-08 | 2014-01-08 | 씨제이제일제당 (주) | 퓨트레신을 생산하는 미생물 및 이를 이용하여 퓨트레신을 생산하는 방법 |
-
2013
- 2013-01-21 AU AU2013210136A patent/AU2013210136B2/en active Active
- 2013-01-21 ES ES13738280.0T patent/ES2682696T3/es active Active
- 2013-01-21 MY MYPI2014002114A patent/MY173018A/en unknown
- 2013-01-21 RU RU2014133769/10A patent/RU2603089C2/ru active
- 2013-01-21 US US14/373,265 patent/US9290771B2/en active Active
- 2013-01-21 JP JP2014553263A patent/JP6251187B2/ja active Active
- 2013-01-21 DK DK13738280.0T patent/DK2806022T3/en active
- 2013-01-21 KR KR20130006707A patent/KR101493586B1/ko active Active
- 2013-01-21 PL PL13738280T patent/PL2806022T3/pl unknown
- 2013-01-21 IN IN1621MUN2014 patent/IN2014MN01621A/en unknown
- 2013-01-21 EP EP13738280.0A patent/EP2806022B1/en active Active
- 2013-01-21 TR TR2018/10509T patent/TR201810509T4/tr unknown
- 2013-01-21 BR BR112014017910-7A patent/BR112014017910B1/pt active IP Right Grant
- 2013-01-21 WO PCT/KR2013/000487 patent/WO2013109121A1/ko active Application Filing
-
2016
- 2016-07-29 JP JP2016150247A patent/JP2017006133A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
BR112014017910A2 (pt) | 2017-11-28 |
EP2806022B1 (en) | 2018-05-23 |
EP2806022A4 (en) | 2015-10-07 |
US20140363859A1 (en) | 2014-12-11 |
TR201810509T4 (tr) | 2018-08-27 |
AU2013210136A1 (en) | 2014-09-11 |
KR20130086010A (ko) | 2013-07-30 |
MY173018A (en) | 2019-12-19 |
JP6251187B2 (ja) | 2017-12-20 |
PL2806022T3 (pl) | 2018-12-31 |
EP2806022A1 (en) | 2014-11-26 |
JP2015506686A (ja) | 2015-03-05 |
KR101493586B1 (ko) | 2015-02-16 |
US9290771B2 (en) | 2016-03-22 |
AU2013210136B2 (en) | 2016-07-07 |
RU2603089C2 (ru) | 2016-11-20 |
BR112014017910B1 (pt) | 2022-04-26 |
IN2014MN01621A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 2015-07-03 |
JP2017006133A (ja) | 2017-01-12 |
CN104136600A (zh) | 2014-11-05 |
ES2682696T3 (es) | 2018-09-21 |
WO2013109121A1 (ko) | 2013-07-25 |
RU2014133769A (ru) | 2016-03-20 |
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