DK2676967T3 - Fremgangsmåder til behandling af inflammatoriske og autoimmune sygdomme med natalizumab - Google Patents
Fremgangsmåder til behandling af inflammatoriske og autoimmune sygdomme med natalizumab Download PDFInfo
- Publication number
- DK2676967T3 DK2676967T3 DK13175987.0T DK13175987T DK2676967T3 DK 2676967 T3 DK2676967 T3 DK 2676967T3 DK 13175987 T DK13175987 T DK 13175987T DK 2676967 T3 DK2676967 T3 DK 2676967T3
- Authority
- DK
- Denmark
- Prior art keywords
- natalizumab
- methods
- autoimmune diseases
- treating inflammatory
- inflammatory
- Prior art date
Links
- 208000023275 Autoimmune disease Diseases 0.000 title 1
- 208000027866 inflammatory disease Diseases 0.000 title 1
- 230000002757 inflammatory effect Effects 0.000 title 1
- 229960005027 natalizumab Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/03—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/215—IFN-beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2842—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta1-subunit-containing molecules, e.g. CD29, CD49
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/01—DNA viruses
- G01N2333/025—Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/06—Gastro-intestinal diseases
- G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/285—Demyelinating diseases; Multipel sclerosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/70—Mechanisms involved in disease identification
- G01N2800/7095—Inflammation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Mycology (AREA)
- Zoology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US77693106P | 2006-02-28 | 2006-02-28 | |
EP07751683A EP1988921A4 (en) | 2006-02-28 | 2007-02-28 | METHOD FOR THE TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES WITH NATALIZUMAB |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2676967T3 true DK2676967T3 (da) | 2019-09-16 |
Family
ID=38459615
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK13175987.0T DK2676967T3 (da) | 2006-02-28 | 2007-02-28 | Fremgangsmåder til behandling af inflammatoriske og autoimmune sygdomme med natalizumab |
Country Status (13)
Country | Link |
---|---|
US (5) | US20070207141A1 (da) |
EP (4) | EP1988921A4 (da) |
JP (2) | JP2009528359A (da) |
CA (2) | CA2641513C (da) |
CY (1) | CY1122031T1 (da) |
DK (1) | DK2676967T3 (da) |
ES (1) | ES2752137T3 (da) |
HU (1) | HUE047230T2 (da) |
LT (1) | LT2676967T (da) |
PL (1) | PL2676967T3 (da) |
PT (1) | PT2676967T (da) |
SI (1) | SI2676967T1 (da) |
WO (1) | WO2007100770A2 (da) |
Families Citing this family (76)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2359697C2 (ru) * | 2002-02-25 | 2009-06-27 | Элан Фармасьютикалз, Инк. | Введение средств для лечения воспаления |
EP2645106B1 (en) | 2005-04-04 | 2017-06-14 | Biogen MA Inc. | Methods for evaluating an immune response to a therapeutic agent |
CA2641160A1 (en) | 2006-02-28 | 2007-09-07 | Elan Pharmaceuticals, Inc. | Methods of treating inflammatory and autoimmune diseases with alpha-4 inhibitory compounds |
PL2676967T3 (pl) | 2006-02-28 | 2019-12-31 | Biogen Ma Inc. | Metody leczenia chorób zapalnych i autoimmunologicznych za pomocą natalizumabu |
EA016626B1 (ru) | 2006-03-03 | 2012-06-29 | Элан Фамэсьютикэлс, Инк. | Способ лечения натализумабом воспалительного и/или аутоиммунного заболевания (варианты) |
EP2789684B1 (en) | 2008-05-23 | 2016-12-21 | Siwa Corporation | Methods and compositions for facilitating regeneration |
CA2749539C (en) | 2009-01-21 | 2022-07-19 | Amgen Inc. | Compositions and methods comprising interleukin-2 mutants for treating inflammatory and autoimmune diseases |
US8415150B2 (en) * | 2009-02-24 | 2013-04-09 | The Trustees Of The University Of Pennsylvania | Methods for treating progressive multifocal leukoencephalopathy (PML) |
BR112012000568A2 (pt) * | 2009-06-19 | 2015-10-06 | Teva Pharma | tratamento da esclerose múltipla com laquinimod |
JP5882208B2 (ja) * | 2009-07-30 | 2016-03-09 | テバ ファーマシューティカル インダストリーズ リミティド | ラキニモドによるクローン病の治療 |
EP3466438A1 (en) | 2009-08-03 | 2019-04-10 | Incube Labs, Llc | Swallowable capsule and method for stimulating incretin production within the intestinal tract |
PL2467372T3 (pl) | 2009-08-10 | 2017-04-28 | Teva Pharmaceutical Industries Ltd. | Leczenie zaburzeń związanych z BDNF z zastosowaniem lakwinimodu |
EP3349010A1 (en) | 2009-10-11 | 2018-07-18 | Biogen MA Inc. | Anti-vla-4 related assays |
US8562589B2 (en) | 2009-12-24 | 2013-10-22 | Rani Therapeutics, Llc | Swallowable drug delivery device and method of delivery |
DK3339865T5 (da) | 2010-01-11 | 2023-03-20 | Biogen Ma Inc | Assay for jc-virus-antistoffer |
US11287423B2 (en) | 2010-01-11 | 2022-03-29 | Biogen Ma Inc. | Assay for JC virus antibodies |
EP2542078B1 (en) | 2010-03-03 | 2015-10-07 | Teva Pharmaceutical Industries Ltd. | Treatment of lupus nephritis using laquinimod |
PT2542080T (pt) * | 2010-03-03 | 2016-11-16 | Teva Pharma | Tratamento de artrite causada por lúpus usando laquinimod |
JP5819328B2 (ja) * | 2010-03-03 | 2015-11-24 | テバ ファーマシューティカル インダストリーズ リミティド | ラキニモドとメトトレキセートとの組合せによる関節リウマチの治療 |
EP3578205A1 (en) | 2010-08-06 | 2019-12-11 | ModernaTX, Inc. | A pharmaceutical formulation comprising engineered nucleic acids and medical use thereof |
CN104531812A (zh) | 2010-10-01 | 2015-04-22 | 现代治疗公司 | 设计核酸及其使用方法 |
SI3326645T1 (sl) | 2010-10-25 | 2020-09-30 | Biogen Ma Inc. | Metode za determinacijo razlik v alfa- 4 integrin aktivnosti s korelacijo razlik v SVCAM in/ali SMADCAM nivojih |
US9283179B2 (en) | 2010-12-23 | 2016-03-15 | Rani Therapeutics, Llc | GnRH preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US8980822B2 (en) | 2010-12-23 | 2015-03-17 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising pramlintide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US8734429B2 (en) | 2010-12-23 | 2014-05-27 | Rani Therapeutics, Llc | Device, system and methods for the oral delivery of therapeutic compounds |
US8809269B2 (en) | 2010-12-23 | 2014-08-19 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising insulin for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US9284367B2 (en) | 2010-12-23 | 2016-03-15 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US9861683B2 (en) | 2010-12-23 | 2018-01-09 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US9415004B2 (en) | 2010-12-23 | 2016-08-16 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US9629799B2 (en) | 2010-12-23 | 2017-04-25 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US8969293B2 (en) | 2010-12-23 | 2015-03-03 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising exenatide for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US10639272B2 (en) | 2010-12-23 | 2020-05-05 | Rani Therapeutics, Llc | Methods for delivering etanercept preparations into a lumen of the intestinal tract using a swallowable drug delivery device |
US9402806B2 (en) | 2010-12-23 | 2016-08-02 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US8846040B2 (en) | 2010-12-23 | 2014-09-30 | Rani Therapeutics, Llc | Therapeutic agent preparations comprising etanercept for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US9402807B2 (en) | 2010-12-23 | 2016-08-02 | Rani Therapeutics, Llc | Therapeutic agent preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
US9259386B2 (en) | 2010-12-23 | 2016-02-16 | Rani Therapeutics, Llc | Therapeutic preparation comprising somatostatin or somatostatin analogoue for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
JP2014511687A (ja) | 2011-03-31 | 2014-05-19 | モデルナ セラピューティクス インコーポレイテッド | 工学操作された核酸の送達および製剤 |
SI3575792T1 (sl) * | 2011-05-31 | 2023-04-28 | Biogen Ma Inc. | Metoda ocenjevanja tveganja progresivne multifokalne levkoencefalopatije |
US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
ES2911677T3 (es) | 2011-10-03 | 2022-05-20 | Modernatx Inc | Nucleósidos, nucleótidos y ácidos nucleicos modificados, y sus usos |
MX2014004420A (es) | 2011-10-12 | 2014-07-09 | Teva Pharma | Tratamiento de esclerosis multiple con combinacion de laquinimod y fingolimod. |
BR112014009310A2 (pt) | 2011-10-17 | 2017-04-11 | Westfaelische Wilhelms-Universitaet Muenster | métodos de avaliação de riscos de lmp e aparelhos relacionados |
WO2013067451A2 (en) | 2011-11-04 | 2013-05-10 | Population Diagnostics Inc. | Methods and compositions for diagnosing, prognosing, and treating neurological conditions |
RS63244B1 (sr) | 2011-12-16 | 2022-06-30 | Modernatx Inc | Kompozicije modifikovane mrna |
WO2013116657A1 (en) | 2012-02-03 | 2013-08-08 | Teva Pharmaceutical Industries Ltd. | USE OF LAQUINIMOD FOR TREATING CROHN'S DISEASE PATIENTS WHO FAILED FIRST-LINE ANTI-TNFα THERAPY |
CA2863887C (en) | 2012-02-09 | 2023-01-03 | Population Diagnostics, Inc. | Methods of screening low frequency gdna variation biomarkers for pervasive developmental disorder (pdd) or pervasive developmental disorder - not otherwise specified (pdd_nos) |
US20140010861A1 (en) | 2012-04-02 | 2014-01-09 | modeRNA Therapeutics | Modified polynucleotides for the production of proteins associated with human disease |
US9878056B2 (en) | 2012-04-02 | 2018-01-30 | Modernatx, Inc. | Modified polynucleotides for the production of cosmetic proteins and peptides |
US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
TW201400117A (zh) | 2012-06-05 | 2014-01-01 | Teva Pharma | 使用拉喹莫德治療眼發炎疾病 |
DK2895621T3 (da) | 2012-09-14 | 2020-11-30 | Population Bio Inc | Fremgangsmåder og sammensætning til diagnosticering, prognose og behandling af neurologiske tilstande |
LT2922554T (lt) | 2012-11-26 | 2022-06-27 | Modernatx, Inc. | Terminaliai modifikuota rnr |
CN103845726A (zh) * | 2012-12-07 | 2014-06-11 | 天津市汉康医药生物技术有限公司 | 克拉屈滨和乙酸格拉默的组合用于治疗多发性硬化的用途 |
US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
EP3004334A4 (en) | 2013-05-28 | 2016-12-21 | Biogen Ma Inc | METHODS OF EVALUATION RISK OF DEVELOPMENT OF PML |
US10023626B2 (en) | 2013-09-30 | 2018-07-17 | Modernatx, Inc. | Polynucleotides encoding immune modulating polypeptides |
KR20160067219A (ko) | 2013-10-03 | 2016-06-13 | 모더나 세라퓨틱스, 인코포레이티드 | 저밀도 지단백질 수용체를 암호화하는 폴리뉴클레오타이드 |
EP2891722B1 (en) | 2013-11-12 | 2018-10-10 | Population Bio, Inc. | Methods and compositions for diagnosing, prognosing, and treating endometriosis |
IL251210B2 (en) * | 2014-09-19 | 2023-12-01 | Siwa Corp | Anti-aging antibodies for the treatment of inflammation and autoimmune disorders |
MA40985A (fr) | 2014-11-17 | 2017-09-26 | Biogen Ma Inc | Méthodes de traitement de la sclérose en plaques |
US9993535B2 (en) | 2014-12-18 | 2018-06-12 | Siwa Corporation | Method and composition for treating sarcopenia |
US10358502B2 (en) | 2014-12-18 | 2019-07-23 | Siwa Corporation | Product and method for treating sarcopenia |
IL304950A (en) | 2015-04-10 | 2023-10-01 | Amgen Inc | Interleukin for the expansion of myotonic control T-2 cells |
WO2018191718A1 (en) | 2017-04-13 | 2018-10-18 | Siwa Corporation | Humanized monoclonal advanced glycation end-product antibody |
CN109071675A (zh) | 2016-02-19 | 2018-12-21 | Siwa有限公司 | 使用高级糖化终产物(age)的抗体治疗癌症、杀死转移性癌细胞和预防癌症转移的方法和组合物 |
US11958900B2 (en) | 2016-04-15 | 2024-04-16 | Siwa Corporation | Anti-age antibodies for treating neurodegenerative disorders |
WO2017222535A1 (en) | 2016-06-23 | 2017-12-28 | Siwa Corporation | Vaccines for use in treating various diseases and disorders |
US10240205B2 (en) | 2017-02-03 | 2019-03-26 | Population Bio, Inc. | Methods for assessing risk of developing a viral disease using a genetic test |
WO2018178973A1 (en) | 2017-03-26 | 2018-10-04 | Mapi Pharma Ltd. | Glatiramer depot systems for treating progressive forms of multiple sclerosis |
US20190108912A1 (en) * | 2017-10-05 | 2019-04-11 | Iquity, Inc. | Methods for predicting or detecting disease |
US11518801B1 (en) | 2017-12-22 | 2022-12-06 | Siwa Corporation | Methods and compositions for treating diabetes and diabetic complications |
WO2019200202A1 (en) | 2018-04-12 | 2019-10-17 | Morphic Therapeutic, Inc. | Antagonists of human integrin (alpha4)(beta7) |
SI3625368T1 (sl) | 2018-08-08 | 2023-04-28 | Pml Screening, Llc | Postopki z genetskim testiranjem za oceno tveganja za razvoj progresivne multifokalne levkoencefalopatije, ki jo povzroča virus John Cunningham |
WO2021076902A1 (en) | 2019-10-16 | 2021-04-22 | Morphic Therapeutic, Inc. | INHIBITING HUMAN INTEGRIN α 4 β 7 |
US20240108653A1 (en) * | 2021-02-05 | 2024-04-04 | University Of Utah Research Foundation | Compositions and methods for treating with car cells |
Family Cites Families (96)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
US3817837A (en) | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
US3939350A (en) | 1974-04-29 | 1976-02-17 | Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing total reflection for activation |
US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
US4277437A (en) | 1978-04-05 | 1981-07-07 | Syva Company | Kit for carrying out chemically induced fluorescence immunoassay |
US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
US4235601A (en) | 1979-01-12 | 1980-11-25 | Thyroid Diagnostics, Inc. | Test device and method for its use |
US4391904A (en) | 1979-12-26 | 1983-07-05 | Syva Company | Test strip kits in immunoassays and compositions therein |
US4376110A (en) | 1980-08-04 | 1983-03-08 | Hybritech, Incorporated | Immunometric assays using monoclonal antibodies |
US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
US4517288A (en) | 1981-01-23 | 1985-05-14 | American Hospital Supply Corp. | Solid phase system for ligand assay |
US4703017C1 (en) | 1984-02-14 | 2001-12-04 | Becton Dickinson Co | Solid phase assay with visual readout |
CA1291031C (en) | 1985-12-23 | 1991-10-22 | Nikolaas C.J. De Jaeger | Method for the detection of specific binding agents and their correspondingbindable substances |
US5763262A (en) | 1986-09-18 | 1998-06-09 | Quidel Corporation | Immunodiagnostic device |
EP0560410B1 (en) | 1987-04-27 | 2002-10-02 | Inverness Medical Switzerland GmbH | A test device for performing specific binding assays |
US4943522A (en) | 1987-06-01 | 1990-07-24 | Quidel | Lateral flow, non-bibulous membrane assay protocols |
US5120643A (en) | 1987-07-13 | 1992-06-09 | Abbott Laboratories | Process for immunochromatography with colloidal particles |
US4818677A (en) | 1987-12-03 | 1989-04-04 | Monoclonal Antibodies, Inc. | Membrane assay using focused sample application |
AU2684488A (en) | 1988-06-27 | 1990-01-04 | Carter-Wallace, Inc. | Test device and method for colored particle immunoassay |
US5221616A (en) | 1988-07-15 | 1993-06-22 | Quidel Corporation | Prevention of spontaneous complement activation in mammalian biological fluids |
US5118630A (en) | 1988-11-04 | 1992-06-02 | Quidel Corporation | Method for determining periodic infertility in females |
US6352862B1 (en) | 1989-02-17 | 2002-03-05 | Unilever Patent Holdings B.V. | Analytical test device for imuno assays and methods of using same |
US6033665A (en) | 1989-09-27 | 2000-03-07 | Elan Pharmaceuticals, Inc. | Compositions and methods for modulating leukocyte adhesion to brain endothelial cells |
US5084828A (en) | 1989-09-29 | 1992-01-28 | Healthtech Services Corp. | Interactive medication delivery system |
US5252496A (en) | 1989-12-18 | 1993-10-12 | Princeton Biomeditech Corporation | Carbon black immunochemical label |
US5096837A (en) | 1990-02-08 | 1992-03-17 | Pacific Biotech, Inc. | Immunochromatographic assay and method of using same |
US5223220A (en) | 1990-03-27 | 1993-06-29 | Pacific Biotech, Inc. | Solid phase immunoassay device and method of making same |
US5118428A (en) | 1990-11-13 | 1992-06-02 | Quidel | Method to remove red blood cells from whole blood samples |
DE4139840B4 (de) | 1990-12-04 | 2005-06-02 | Quidel Corp., San Diego | Antigen-Zubereitung zum Nachweis von H. pylori |
JP2868900B2 (ja) | 1991-01-11 | 1999-03-10 | クイデル コーポレイション | ワンステップ側方流非吸収性アッセイ |
US5213796A (en) | 1991-05-06 | 1993-05-25 | Dana Farber Cancer Institute | Assay for polyomavirus in humans and uses thereof |
US5225328A (en) | 1991-05-30 | 1993-07-06 | Quidel Corporation | Stable alkaline phosphatase compositions with color enhancement and their use in assays |
US5686315A (en) | 1991-06-14 | 1997-11-11 | Quidel Corporation | Assay device for one step detection of analyte |
WO1993015217A1 (en) | 1992-02-04 | 1993-08-05 | Quidel Corporation | Simplified extraction method for bacterial antigens using dried reagents |
US5541069A (en) | 1992-02-28 | 1996-07-30 | Quidel Corporation | Assay having improved dose response curve |
JP2948318B2 (ja) | 1992-03-10 | 1999-09-13 | クイデル コーポレイション | 特異的結合アッセイ用の赤血球の分離方法 |
NZ261259A (en) | 1993-01-12 | 1996-12-20 | Biogen Inc | Humanised recombinant anti-vla4 antibody and diagnostic compositions and medicaments |
US5415994A (en) | 1993-08-02 | 1995-05-16 | Quidel Corporation | Lateral flow medical diagnostic assay device with sample extraction means |
US5840299A (en) | 1994-01-25 | 1998-11-24 | Athena Neurosciences, Inc. | Humanized antibodies against leukocyte adhesion molecule VLA-4 |
US5434057A (en) | 1994-02-02 | 1995-07-18 | Quidel Corporation | Sperm motility assay and devices |
US5521102A (en) | 1994-08-08 | 1996-05-28 | Quidel Corporation | Controlled sensitivity immunochromatographic assay |
US5845255A (en) | 1994-10-28 | 1998-12-01 | Advanced Health Med-E-Systems Corporation | Prescription management system |
US6551593B1 (en) | 1995-02-10 | 2003-04-22 | Millennium Pharmaceuticals, Inc. | Treatment of Inflammatory bowel disease by inhibiting binding and/or signalling through α 4 β 7 and its ligands and madcam |
US5712172A (en) | 1995-05-18 | 1998-01-27 | Wyntek Diagnostics, Inc. | One step immunochromatographic device and method of use |
US5804452A (en) | 1995-04-27 | 1998-09-08 | Quidel Corporation | One step urine creatinine assays |
US5786220A (en) | 1995-04-28 | 1998-07-28 | Quidel Corporation | Assays and devices for distinguishing between normal and abnormal pregnancy |
US6319676B1 (en) | 1995-05-02 | 2001-11-20 | Carter Wallace, Inc. | Diagnostic detection device and method |
US5773234A (en) | 1995-08-07 | 1998-06-30 | Quidel Corporation | Method and device for chlamydia detection |
DE19543553B4 (de) * | 1995-11-22 | 2009-04-09 | Deutsches Primatenzentrum Gmbh | VP-Antigene des JC-Virus |
US6305377B1 (en) | 1996-12-12 | 2001-10-23 | Michael T. Portwood | System and method for improving compliance of a medical regimen |
US6229011B1 (en) * | 1997-08-22 | 2001-05-08 | Hoffman-La Roche Inc. | N-aroylphenylalanine derivative VCAM-1 inhibitors |
US6306642B1 (en) | 1997-11-24 | 2001-10-23 | Quidel Corporation | Enzyme substrate delivery and product registration in one step enzyme immunoassays |
US6623981B2 (en) | 1998-01-27 | 2003-09-23 | Bristol-Myers Squibb Company | Detection of patients at risk for developing integrin antagonist/agonist mediated disease states |
US6014631A (en) | 1998-04-02 | 2000-01-11 | Merck-Medco Managed Care, Llc | Computer implemented patient medication review system and process for the managed care, health care and/or pharmacy industry |
US6045501A (en) | 1998-08-28 | 2000-04-04 | Celgene Corporation | Methods for delivering a drug to a patient while preventing the exposure of a foetus or other contraindicated individual to the drug |
US6407066B1 (en) * | 1999-01-26 | 2002-06-18 | Elan Pharmaceuticals, Inc. | Pyroglutamic acid derivatives and related compounds which inhibit leukocyte adhesion mediated by VLA-4 |
US7171371B2 (en) | 1999-09-03 | 2007-01-30 | Smg Trust | Method and system for providing pre and post operative support and care |
JP2003511698A (ja) | 1999-10-12 | 2003-03-25 | コンネクス・ゲゼルシャフト・ツーア・オプティミエルング・フォン・フォルシュング・ウント・エントヴィックルング・エムベーハー | 便中の酸耐性微生物の改良された検出方法 |
US6388084B1 (en) * | 1999-12-06 | 2002-05-14 | Hoffmann-La Roche Inc. | 4-pyridinyl-n-acyl-l-phenylalanines |
CA2394431C (en) * | 1999-12-16 | 2015-06-30 | Jane Relton | Methods of treating central nervous system ischemic or hemorrhagic injury using anti alpha4 integrin antagonists |
WO2001075449A1 (fr) | 2000-03-30 | 2001-10-11 | Nippon Kayaku Kabushiki Kaisha | Technique d'investigation du cancer par epreuve biologique d'un autoanticorps contre mdm2 et reactif |
US6620626B1 (en) | 2000-08-09 | 2003-09-16 | Mission Research Corp. | Antigen detection device and method |
MY129000A (en) * | 2000-08-31 | 2007-03-30 | Tanabe Seiyaku Co | INHIBITORS OF a4 MEDIATED CELL ADHESION |
DK1340086T3 (da) | 2000-10-17 | 2008-12-01 | Besst Test Aps | Assay til direkte detektion af en RS-virusrelateret biologisk celle i en legemsvæskepröve |
US6315720B1 (en) | 2000-10-23 | 2001-11-13 | Celgene Corporation | Methods for delivering a drug to a patient while avoiding the occurrence of an adverse side effect known or suspected of being caused by the drug |
US6485460B2 (en) | 2001-01-12 | 2002-11-26 | Bracco Diagnostics, Inc. | Tamper evident syringe barrel |
ATE539816T1 (de) | 2001-08-20 | 2012-01-15 | Proteome Systems Ltd | Verfahren zum diagnostischen testen |
WO2003016902A1 (en) | 2001-08-20 | 2003-02-27 | Proteome Systems Intellectual Property Pty Ltd | Diagnostic testing process and apparatus |
US6605602B1 (en) * | 2001-09-28 | 2003-08-12 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Method of treating BK virus nephropathy |
US7754433B2 (en) | 2001-12-03 | 2010-07-13 | Amgen Fremont Inc. | Identification of high affinity molecules by limited dilution screening |
RU2359697C2 (ru) * | 2002-02-25 | 2009-06-27 | Элан Фармасьютикалз, Инк. | Введение средств для лечения воспаления |
TW200307671A (en) * | 2002-05-24 | 2003-12-16 | Elan Pharm Inc | Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins |
TWI281470B (en) * | 2002-05-24 | 2007-05-21 | Elan Pharm Inc | Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha4 integrins |
WO2004001539A2 (en) | 2002-06-21 | 2003-12-31 | Mckesson Information Solutions Llc | Closed loop medication use system and method |
US20070275481A1 (en) | 2003-11-24 | 2007-11-29 | Biogen Idec Ma Inc. | Methods For Detecting Half-Antibodies Using Chip Based Gel Electophoresis |
JP4672263B2 (ja) | 2004-01-27 | 2011-04-20 | デンカ生研株式会社 | 簡便な検出法、検出装置及び検出キットとその製法 |
US7419666B1 (en) | 2004-02-23 | 2008-09-02 | Massachusetts Eye And Ear Infirmary | Treatment of ocular disorders |
TWI556829B (zh) * | 2004-04-09 | 2016-11-11 | 艾伯維生物技術有限責任公司 | 用於治療TNFα相關失調症之多重可變劑量療法 |
US20050283385A1 (en) | 2004-06-21 | 2005-12-22 | The Permanente Medical Group, Inc. | Individualized healthcare management system |
NZ588839A (en) * | 2004-07-08 | 2012-09-28 | Elan Pharm Inc | Multivalent vla-4 antagonists comprising polyethylene glycol moieties |
CA2478458A1 (en) | 2004-08-20 | 2006-02-20 | Michael Panzara | Treatment of pediatric multiple sclerosis |
NZ581497A (en) | 2004-12-03 | 2012-07-27 | Biogen Idec Inc | Delaying or preventing onset of multiple sclerosis by vla-4 ginding antibody |
ES2387317T3 (es) | 2005-03-03 | 2012-09-20 | Seedlings Life Science Ventures, Llc. | Procedimiento de control de riesgos de pacientes en tratamiento con natalizumab |
EP2645106B1 (en) | 2005-04-04 | 2017-06-14 | Biogen MA Inc. | Methods for evaluating an immune response to a therapeutic agent |
BRPI0616687A2 (pt) | 2005-09-29 | 2011-06-28 | Elan Pharm Inc | compostos de pirimidinil amida que inibem a adesão leucocitária mediada por vla-4 |
JP5135235B2 (ja) | 2006-02-27 | 2013-02-06 | エラン ファーマシューティカルズ,インコーポレイテッド | Val−4によって媒介される白血球の接着を阻害するピリミジニルスルホンアミド化合物 |
CA2641160A1 (en) | 2006-02-28 | 2007-09-07 | Elan Pharmaceuticals, Inc. | Methods of treating inflammatory and autoimmune diseases with alpha-4 inhibitory compounds |
PL2676967T3 (pl) | 2006-02-28 | 2019-12-31 | Biogen Ma Inc. | Metody leczenia chorób zapalnych i autoimmunologicznych za pomocą natalizumabu |
EA016626B1 (ru) | 2006-03-03 | 2012-06-29 | Элан Фамэсьютикэлс, Инк. | Способ лечения натализумабом воспалительного и/или аутоиммунного заболевания (варианты) |
US20080233150A1 (en) | 2006-11-16 | 2008-09-25 | Gale Smith | Respiratory syncytial virus-virus like particle (vlps) |
EP1933140B1 (en) | 2006-12-11 | 2011-08-17 | AraGen Biotechnology Co. Ltd. | Antibody detection method involving an oligonucleotide enhanced collodial gold signal |
WO2010090757A1 (en) | 2009-02-05 | 2010-08-12 | Biogen Idec Ma Inc. | Methods for the detection of jc polyoma virus |
WO2010096674A2 (en) | 2009-02-20 | 2010-08-26 | The Regents Of The University Of California | A+ biomarker assays |
DK3339865T5 (da) | 2010-01-11 | 2023-03-20 | Biogen Ma Inc | Assay for jc-virus-antistoffer |
SI3575792T1 (sl) | 2011-05-31 | 2023-04-28 | Biogen Ma Inc. | Metoda ocenjevanja tveganja progresivne multifokalne levkoencefalopatije |
EP3004334A4 (en) | 2013-05-28 | 2016-12-21 | Biogen Ma Inc | METHODS OF EVALUATION RISK OF DEVELOPMENT OF PML |
-
2007
- 2007-02-28 PL PL13175987T patent/PL2676967T3/pl unknown
- 2007-02-28 DK DK13175987.0T patent/DK2676967T3/da active
- 2007-02-28 ES ES13175987T patent/ES2752137T3/es active Active
- 2007-02-28 SI SI200732136T patent/SI2676967T1/sl unknown
- 2007-02-28 CA CA2641513A patent/CA2641513C/en active Active
- 2007-02-28 EP EP07751683A patent/EP1988921A4/en not_active Withdrawn
- 2007-02-28 CA CA3127202A patent/CA3127202A1/en active Pending
- 2007-02-28 US US11/711,628 patent/US20070207141A1/en not_active Abandoned
- 2007-02-28 WO PCT/US2007/004943 patent/WO2007100770A2/en active Application Filing
- 2007-02-28 EP EP13175987.0A patent/EP2676967B1/en not_active Revoked
- 2007-02-28 JP JP2008557327A patent/JP2009528359A/ja not_active Withdrawn
- 2007-02-28 LT LTEP13175987.0T patent/LT2676967T/lt unknown
- 2007-02-28 EP EP19190770.8A patent/EP3620469A1/en not_active Withdrawn
- 2007-02-28 HU HUE13175987A patent/HUE047230T2/hu unknown
- 2007-02-28 EP EP23199522.6A patent/EP4276469A3/en active Pending
- 2007-02-28 PT PT13175987T patent/PT2676967T/pt unknown
-
2010
- 2010-04-09 US US12/757,305 patent/US9493567B2/en active Active
-
2014
- 2014-09-02 JP JP2014178049A patent/JP2015007103A/ja active Pending
-
2016
- 2016-10-04 US US15/285,381 patent/US20170022276A1/en not_active Abandoned
-
2017
- 2017-05-16 US US15/596,468 patent/US10233245B2/en active Active
-
2019
- 2019-03-18 US US16/357,179 patent/US11292845B2/en active Active
- 2019-09-12 CY CY20191100955T patent/CY1122031T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
CA2641513C (en) | 2021-09-21 |
WO2007100770A2 (en) | 2007-09-07 |
SI2676967T1 (sl) | 2020-01-31 |
US10233245B2 (en) | 2019-03-19 |
ES2752137T3 (es) | 2020-04-03 |
JP2015007103A (ja) | 2015-01-15 |
EP2676967A3 (en) | 2014-03-05 |
LT2676967T (lt) | 2019-09-10 |
US20070207141A1 (en) | 2007-09-06 |
US11292845B2 (en) | 2022-04-05 |
US20170247457A1 (en) | 2017-08-31 |
EP4276469A3 (en) | 2024-01-17 |
CY1122031T1 (el) | 2020-10-14 |
PL2676967T3 (pl) | 2019-12-31 |
US20100196318A1 (en) | 2010-08-05 |
EP1988921A4 (en) | 2010-02-10 |
PT2676967T (pt) | 2019-09-27 |
US9493567B2 (en) | 2016-11-15 |
EP2676967A2 (en) | 2013-12-25 |
US20170022276A1 (en) | 2017-01-26 |
CA2641513A1 (en) | 2007-09-07 |
EP2676967B1 (en) | 2019-08-14 |
HUE047230T2 (hu) | 2020-04-28 |
EP1988921A2 (en) | 2008-11-12 |
CA3127202A1 (en) | 2007-09-07 |
EP3620469A1 (en) | 2020-03-11 |
JP2009528359A (ja) | 2009-08-06 |
US20190315871A1 (en) | 2019-10-17 |
WO2007100770A3 (en) | 2008-12-11 |
EP4276469A2 (en) | 2023-11-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK2676967T3 (da) | Fremgangsmåder til behandling af inflammatoriske og autoimmune sygdomme med natalizumab | |
HK1256238A1 (zh) | 用那他珠單抗治療炎性疾病和自身免疫疾病的方法 | |
DK1874781T3 (da) | Dihydrothienopyrimidiner til behandling af inflammatoriske sygdomme | |
DK1888033T3 (da) | Fremgangsmåde og sammensætning til behandling af inflammatoriske sygdomme | |
DK2068874T3 (da) | Fremgangsmåder til behandling af multiple myelom med anvendelse af kombinationsterapier baseret på anti-cs1 antistoffer | |
DK2046819T3 (da) | Fremgangsmåder til forøgelse af secernering af polypeptider med biologisk aktivitet | |
DK2190984T3 (da) | Fremgangsmåder og kits til oprensning og påvisning af glycosyleret IgG | |
DK3381933T3 (da) | Muteiner af hngal og relaterede proteiner med affinitet til et givet mål | |
DK2371958T3 (da) | HIDTIL UKENDTE siRNA OG FREMGANGSMÅDER TIL ANVENDELSE DERAF | |
DK2495327T3 (da) | Fremgangsmåder og sammensætninger til at behandle og opdage sygdomme fremkaldt af fejlfoldet SOD1 | |
DK2222675T3 (da) | 5-anilinoimidazopyridiner og fremgangsmåder til deres anvendelse | |
DK2056807T3 (da) | Behandling af inflammatoriske sygdomme | |
DK3702371T3 (da) | Anti-FGFR3-antistoffer og fremgangsmåder ved anvendelse af disse | |
DK2152748T3 (da) | Anti-Notch1-NRR-antistoffer og fremgangsmåder til anvendelse deraf | |
DK3002298T3 (da) | Anti-faktor xi monoklonale antistoffer og fremgangsmåder til anvendelse deraf | |
DK2557180T3 (da) | Fremgangsmåder til påvisning af autoimmune lidelser | |
DK1979061T3 (da) | Forbindelsesorgan til konstruktionselementer og byggebloksæt med dette | |
DK2066817T3 (da) | Molekylære afbrydere og fremgangsmåder til anvendelse deraf | |
DK2445912T3 (da) | Ny forbindelse anvendelig til behandlingen af degenerative og inflammatoriske sygdomme | |
DK2170827T3 (da) | Indolin-2-oner og aza-indolin-2-oner | |
DK2222314T3 (da) | Anvendelser og midler til opnåelse af bronchorelaxation | |
DK3444613T3 (da) | Fremgangsmåder til diagnosticering og behandling af autisme | |
DK2443577T3 (da) | Fremgangsmåder og systemer til rådgivning af personer med diabetes | |
DK2337837T3 (da) | Alpha-amylase-blandinger og fremgangsmåder til anvendelse heraf | |
DK2228629T3 (da) | System og fremgangsmåde til bestemmelse af positionen af en motordel |