PL2467372T3 - Leczenie zaburzeń związanych z BDNF z zastosowaniem lakwinimodu - Google Patents
Leczenie zaburzeń związanych z BDNF z zastosowaniem lakwinimoduInfo
- Publication number
- PL2467372T3 PL2467372T3 PL10808442T PL10808442T PL2467372T3 PL 2467372 T3 PL2467372 T3 PL 2467372T3 PL 10808442 T PL10808442 T PL 10808442T PL 10808442 T PL10808442 T PL 10808442T PL 2467372 T3 PL2467372 T3 PL 2467372T3
- Authority
- PL
- Poland
- Prior art keywords
- laquinimod
- bdnf
- treatment
- related disorders
- disorders
- Prior art date
Links
- 101150035467 BDNF gene Proteins 0.000 title 1
- GKWPCEFFIHSJOE-UHFFFAOYSA-N laquinimod Chemical compound OC=1C2=C(Cl)C=CC=C2N(C)C(=O)C=1C(=O)N(CC)C1=CC=CC=C1 GKWPCEFFIHSJOE-UHFFFAOYSA-N 0.000 title 1
- 229960004577 laquinimod Drugs 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27392009P | 2009-08-10 | 2009-08-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2467372T3 true PL2467372T3 (pl) | 2017-04-28 |
Family
ID=43535297
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL10808442T PL2467372T3 (pl) | 2009-08-10 | 2010-08-09 | Leczenie zaburzeń związanych z BDNF z zastosowaniem lakwinimodu |
| PL16160522T PL3064206T3 (pl) | 2009-08-10 | 2010-08-09 | Leczenie choroby Huntingtona z zastosowaniem lakwinimodu |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL16160522T PL3064206T3 (pl) | 2009-08-10 | 2010-08-09 | Leczenie choroby Huntingtona z zastosowaniem lakwinimodu |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US9585878B2 (pl) |
| EP (2) | EP2467372B1 (pl) |
| JP (1) | JP5859438B2 (pl) |
| AU (2) | AU2010282948C1 (pl) |
| CA (1) | CA2771203C (pl) |
| CY (1) | CY1117916T1 (pl) |
| DK (1) | DK2467372T3 (pl) |
| ES (2) | ES2586843T3 (pl) |
| HK (1) | HK1225970A1 (pl) |
| HR (1) | HRP20160997T1 (pl) |
| HU (1) | HUE029983T2 (pl) |
| IL (1) | IL217901B (pl) |
| ME (1) | ME02495B (pl) |
| PL (2) | PL2467372T3 (pl) |
| PT (1) | PT2467372T (pl) |
| RS (1) | RS55071B1 (pl) |
| SI (1) | SI2467372T1 (pl) |
| SM (1) | SMT201600281B (pl) |
| WO (1) | WO2011019375A1 (pl) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1937642T1 (sl) * | 2005-10-19 | 2015-01-30 | Teva Pharmaceutical Industries Ltd. | Kristali natrijevega lakvinimoda in postopek za njihovo pripravo |
| CN101466379B (zh) | 2006-06-12 | 2012-10-31 | 泰华制药工业有限公司 | 稳定的拉喹莫德的制剂 |
| EP2234485B1 (en) | 2007-12-20 | 2013-11-13 | Teva Pharmaceutical Industries, Ltd. | Stable laquinimod preparations |
| KR20110048571A (ko) * | 2008-09-03 | 2011-05-11 | 테바 파마슈티컬 인더스트리즈 리미티드 | 면역 기능을 지닌 2―옥소―1,2―다이하이드로―퀴놀린 조절제 |
| RS54707B1 (sr) * | 2009-07-30 | 2016-08-31 | Teva Pharmaceutical Industries Ltd. | Tretman kronove bolesti lakvinimodom |
| PL2467372T3 (pl) * | 2009-08-10 | 2017-04-28 | Teva Pharmaceutical Industries Ltd. | Leczenie zaburzeń związanych z BDNF z zastosowaniem lakwinimodu |
| KR20130014523A (ko) * | 2010-03-03 | 2013-02-07 | 테바 파마슈티컬 인더스트리즈 리미티드 | 라퀴니모드 및 메토트렉세이트의 병용에 의한 류마티스 관절염의 치료 |
| US8889661B2 (en) * | 2010-03-03 | 2014-11-18 | Teva Pharmaceutical Industries, Ltd. | Treatment of lupus nephritis using laquinimod |
| PH12012501741A1 (en) * | 2010-03-03 | 2012-11-12 | Teva Pharma | Treatment of lupus arthritis using laquinimod |
| SG186948A1 (en) | 2010-07-09 | 2013-02-28 | Teva Pharma | Deuterated n-ethyl-n-phenyl-1,2-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide, salts and uses thereof |
| JP2014521658A (ja) * | 2011-07-28 | 2014-08-28 | テバ ファーマシューティカル インダストリーズ リミティド | ラキニモドおよび酢酸グラチラマーを組み合わせた多発性硬化症の治療 |
| US8889627B2 (en) | 2011-10-12 | 2014-11-18 | Teva Pharmaceutical Industries, Ltd. | Treatment of multiple sclerosis with combination of laquinimod and fingolimod |
| US9161935B2 (en) | 2012-02-03 | 2015-10-20 | Teva Pharmaceutical Industries, Ltd. | Use of laquinimod for treating Crohn's disease patients who failed first-line anti-TNF therapy |
| EA201491517A1 (ru) | 2012-02-16 | 2015-03-31 | Тева Фармасьютикал Индастриз Лтд. | N-этил-n-фенил-1,2-дигидро-4,5-дигидрокси-1-метил-2-оксо-3-хинолинкарбоксамид, его получение и применения |
| TW201350467A (zh) | 2012-05-08 | 2013-12-16 | Teva Pharma | N-乙基-4-羥基-1-甲基-5-(甲基(2,3,4,5,6-五羥基己基)胺基)-2-側氧-n-苯基-1,2-二氫喹啉-3-甲醯胺 |
| TW201400117A (zh) | 2012-06-05 | 2014-01-01 | Teva Pharma | 使用拉喹莫德治療眼發炎疾病 |
| TW201410243A (zh) * | 2012-08-13 | 2014-03-16 | Teva Pharma | 用於治療大麻素受體型1(cb1)媒介之疾病之拉喹莫德(laquinimod) |
| TW201410244A (zh) * | 2012-08-13 | 2014-03-16 | Teva Pharma | 用於治療gaba媒介之疾病之拉喹莫德(laquinimod) |
| US20140088140A1 (en) * | 2012-09-27 | 2014-03-27 | Teva Pharmaceutical Industries, Ltd. | Combination of laquinimod and pridopidine for treating neurodegenerative disorders, in particular huntington's disease |
| EP2961406A4 (en) * | 2012-10-12 | 2017-01-04 | Teva Pharmaceutical Industries Ltd. | Laquinimod for reducing thalamic damage in multiple sclerosis |
| CN104955522A (zh) | 2012-11-07 | 2015-09-30 | 梯瓦制药工业有限公司 | 拉喹莫德胺盐 |
| WO2014153145A2 (en) | 2013-03-14 | 2014-09-25 | Teva Pharmaceutical Industries Ltd. | Crystals of laquinimod sodium and improved process for the manufacture thereof |
| WO2014152009A1 (en) | 2013-03-14 | 2014-09-25 | Teva Pharmaceutical Industries Ltd. | Transdermal formulations of laquinimod |
| JP2016537364A (ja) * | 2013-11-15 | 2016-12-01 | テバ ファーマシューティカル インダストリーズ リミティド | ラキニモドを用いた緑内障の治療 |
| KR20160110395A (ko) * | 2013-12-20 | 2016-09-21 | 테바 파마슈티컬 인더스트리즈 리미티드 | 헌팅턴병 진행을 지연시키기 위한 라퀴니모드의 용도 |
| WO2015168103A1 (en) | 2014-04-29 | 2015-11-05 | Teva Pharmaceutical Industries Ltd. | Laquinimod for the treatment of relapsing-remitting multiple sclerosis (rrms) patients with a high disability status |
| CA2961187A1 (en) * | 2014-09-16 | 2016-03-24 | Teva Pharmaceuticals Industries Ltd. | Treatment of neurodegenerative diseases with combination of laquinimod and fingolimod |
| KR20210045423A (ko) * | 2018-08-16 | 2021-04-26 | 바이오하벤 테라퓨틱스 리미티드 | 질환 치료를 위한 릴루졸 경구 붕해 정제의 용도 |
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| AR073295A1 (es) | 2008-09-16 | 2010-10-28 | Genentech Inc | Metodos para tratar la esclerosis multiple progresiva. articulo de fabricacion. |
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| EA201270041A1 (ru) | 2009-06-19 | 2012-06-29 | Тева Фармасьютикал Индастриз Лтд. | Лечение рассеянного склероза лаквинимодом |
| PL2467372T3 (pl) * | 2009-08-10 | 2017-04-28 | Teva Pharmaceutical Industries Ltd. | Leczenie zaburzeń związanych z BDNF z zastosowaniem lakwinimodu |
| US8889661B2 (en) | 2010-03-03 | 2014-11-18 | Teva Pharmaceutical Industries, Ltd. | Treatment of lupus nephritis using laquinimod |
| PH12012501741A1 (en) | 2010-03-03 | 2012-11-12 | Teva Pharma | Treatment of lupus arthritis using laquinimod |
| KR20130014523A (ko) | 2010-03-03 | 2013-02-07 | 테바 파마슈티컬 인더스트리즈 리미티드 | 라퀴니모드 및 메토트렉세이트의 병용에 의한 류마티스 관절염의 치료 |
| KR20130041193A (ko) | 2010-07-09 | 2013-04-24 | 테바 파마슈티컬 인더스트리즈 리미티드 | 5-클로로-4-하이드록시-1-메틸-2-옥소-n-페닐-1,2-다이하이드로퀴놀린-3-카복스아마이드, 염 및 그의 용도 |
| SG186948A1 (en) | 2010-07-09 | 2013-02-28 | Teva Pharma | Deuterated n-ethyl-n-phenyl-1,2-dihydro-4-hydroxy-5-chloro-1-methyl-2-oxoquinoline-3-carboxamide, salts and uses thereof |
| EP2648732A4 (en) | 2010-12-07 | 2014-04-30 | Teva Pharma | USE OF LAQUINIMOD TO REDUCE TEMPERATURE, IMPROVE FUNCTIONAL STATUS AND IMPROVE LIFE QUALITY IN PATIENTS WITH MULTIPLE SCLEROSIS |
| US8889627B2 (en) | 2011-10-12 | 2014-11-18 | Teva Pharmaceutical Industries, Ltd. | Treatment of multiple sclerosis with combination of laquinimod and fingolimod |
-
2010
- 2010-08-09 PL PL10808442T patent/PL2467372T3/pl unknown
- 2010-08-09 US US12/806,275 patent/US9585878B2/en active Active
- 2010-08-09 SI SI201031245A patent/SI2467372T1/sl unknown
- 2010-08-09 PL PL16160522T patent/PL3064206T3/pl unknown
- 2010-08-09 RS RS20160664A patent/RS55071B1/sr unknown
- 2010-08-09 EP EP10808442.7A patent/EP2467372B1/en active Active
- 2010-08-09 JP JP2012524692A patent/JP5859438B2/ja not_active Expired - Fee Related
- 2010-08-09 AU AU2010282948A patent/AU2010282948C1/en active Active
- 2010-08-09 HU HUE10808442A patent/HUE029983T2/en unknown
- 2010-08-09 ES ES10808442.7T patent/ES2586843T3/es active Active
- 2010-08-09 HR HRP20160997TT patent/HRP20160997T1/hr unknown
- 2010-08-09 CA CA2771203A patent/CA2771203C/en active Active
- 2010-08-09 ES ES16160522T patent/ES2731052T3/es active Active
- 2010-08-09 DK DK10808442.7T patent/DK2467372T3/en active
- 2010-08-09 ME MEP-2016-162A patent/ME02495B/me unknown
- 2010-08-09 PT PT108084427T patent/PT2467372T/pt unknown
- 2010-08-09 EP EP16160522.5A patent/EP3064206B1/en active Active
- 2010-08-09 WO PCT/US2010/002194 patent/WO2011019375A1/en not_active Ceased
-
2012
- 2012-02-02 IL IL217901A patent/IL217901B/en active IP Right Grant
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2016
- 2016-02-22 US US15/049,942 patent/US20160243103A1/en not_active Abandoned
- 2016-08-16 CY CY20161100805T patent/CY1117916T1/el unknown
- 2016-08-18 SM SM201600281T patent/SMT201600281B/it unknown
- 2016-12-16 HK HK16114333.9A patent/HK1225970A1/en unknown
- 2016-12-21 AU AU2016277618A patent/AU2016277618A1/en not_active Abandoned
-
2017
- 2017-02-07 US US15/426,626 patent/US20170239234A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| PT2467372T (pt) | 2016-08-23 |
| CY1117916T1 (el) | 2017-05-17 |
| JP5859438B2 (ja) | 2016-02-10 |
| ES2586843T3 (es) | 2016-10-19 |
| US20110034508A1 (en) | 2011-02-10 |
| HK1225970A1 (en) | 2017-09-22 |
| US9585878B2 (en) | 2017-03-07 |
| IL217901B (en) | 2018-12-31 |
| AU2016277618A1 (en) | 2017-01-19 |
| AU2010282948C1 (en) | 2017-03-02 |
| AU2010282948A1 (en) | 2012-04-05 |
| HRP20160997T1 (hr) | 2016-10-07 |
| AU2010282948B2 (en) | 2016-09-29 |
| EP2467372B1 (en) | 2016-05-18 |
| SMT201600281B (it) | 2016-11-10 |
| ES2731052T3 (es) | 2019-11-13 |
| EP3064206B1 (en) | 2019-03-20 |
| US20160243103A1 (en) | 2016-08-25 |
| CA2771203C (en) | 2019-04-09 |
| JP2013501784A (ja) | 2013-01-17 |
| SI2467372T1 (sl) | 2016-09-30 |
| RS55071B1 (sr) | 2016-12-30 |
| HUE029983T2 (en) | 2017-04-28 |
| CA2771203A1 (en) | 2011-02-17 |
| IL217901A0 (en) | 2012-03-29 |
| US20170239234A1 (en) | 2017-08-24 |
| EP3064206A1 (en) | 2016-09-07 |
| PL3064206T3 (pl) | 2020-02-28 |
| WO2011019375A1 (en) | 2011-02-17 |
| EP2467372A4 (en) | 2013-01-09 |
| ME02495B (me) | 2017-02-20 |
| DK2467372T3 (en) | 2016-08-22 |
| EP2467372A1 (en) | 2012-06-27 |
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