HK1256238A1 - 用那他珠單抗治療炎性疾病和自身免疫疾病的方法 - Google Patents
用那他珠單抗治療炎性疾病和自身免疫疾病的方法Info
- Publication number
- HK1256238A1 HK1256238A1 HK18115236.2A HK18115236A HK1256238A1 HK 1256238 A1 HK1256238 A1 HK 1256238A1 HK 18115236 A HK18115236 A HK 18115236A HK 1256238 A1 HK1256238 A1 HK 1256238A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- natalizumab
- methods
- autoimmune diseases
- treating inflammatory
- inflammatory
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
- C07K16/2842—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta1-subunit-containing molecules, e.g. CD29, CD49
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Urology & Nephrology (AREA)
- Genetics & Genomics (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Oncology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US77919006P | 2006-03-03 | 2006-03-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1256238A1 true HK1256238A1 (zh) | 2019-09-20 |
Family
ID=38475386
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18115236.2A HK1256238A1 (zh) | 2006-03-03 | 2018-11-28 | 用那他珠單抗治療炎性疾病和自身免疫疾病的方法 |
Country Status (18)
Country | Link |
---|---|
US (4) | US20070231319A1 (zh) |
EP (2) | EP3360900A1 (zh) |
JP (2) | JP5504390B2 (zh) |
KR (1) | KR20080104343A (zh) |
CN (1) | CN101437541A (zh) |
AU (1) | AU2007224228B2 (zh) |
BR (1) | BRPI0708392A2 (zh) |
CA (1) | CA2644110A1 (zh) |
EA (1) | EA016626B1 (zh) |
ES (1) | ES2663377T3 (zh) |
HK (1) | HK1256238A1 (zh) |
IL (1) | IL193775A (zh) |
MA (1) | MA30287B1 (zh) |
MX (1) | MX2008011176A (zh) |
RS (1) | RS20080391A (zh) |
SG (1) | SG170058A1 (zh) |
WO (1) | WO2007103112A2 (zh) |
ZA (1) | ZA200807346B (zh) |
Families Citing this family (33)
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SI2645106T1 (en) | 2005-04-04 | 2018-01-31 | Biogen Ma Inc. | METHODS FOR EVALUATION OF THE IMMUNE RESPONSE TO THERAPEUTIC MEDICINE |
US8410115B2 (en) | 2006-02-28 | 2013-04-02 | Elan Pharmaceuticals, Inc. | Methods of treating inflammatory and autoimmune diseases with alpha-4 inhibitory compounds |
LT2676967T (lt) | 2006-02-28 | 2019-09-10 | Biogen Ma Inc. | Uždegiminių ir autoimuninių ligų gydymo būdai su natalizumabu |
ES2663377T3 (es) | 2006-03-03 | 2018-04-12 | Biogen Ma Inc. | Métodos para el tratamiento de enfermedades inflamatorias y autoinmunes con natalizumab |
EP2626372B1 (en) * | 2007-03-29 | 2018-03-21 | Genmab A/S | Bispecific antibodies and methods for production thereof |
ES2824261T3 (es) * | 2007-09-14 | 2021-05-11 | Biogen Ma Inc | Composiciones y procedimientos para el tratamiento de la leucoencefalopatía multifocal progresiva (LMP) |
EP2226392A1 (en) * | 2009-03-03 | 2010-09-08 | Assistance Publique - Hôpitaux de Paris | Method for detecting JCV infection |
AU2010260455A1 (en) * | 2009-06-19 | 2012-02-02 | Teva Pharmaceutical Industries Ltd. | Treatment of multiple sclerosis with laquinimod |
SI2458992T1 (sl) * | 2009-07-30 | 2016-03-31 | Teva Pharmaceutical Industries Ltd. | Zdravljenje Crohnove bolezni z lakvinimodom |
JP5859438B2 (ja) | 2009-08-10 | 2016-02-10 | テバ ファーマシューティカル インダストリーズ リミティド | ラキニモドを用いたbdnf関連疾患の治療 |
AU2010303156B2 (en) * | 2009-10-11 | 2016-02-04 | Biogen Ma Inc. | Anti-VLA-4 related assays |
BR112012017014B1 (pt) | 2010-01-11 | 2021-07-20 | Biogen Ma Inc | Métodos para detecção de anticorpos de vírus jc |
US11287423B2 (en) | 2010-01-11 | 2022-03-29 | Biogen Ma Inc. | Assay for JC virus antibodies |
BR112012022187A2 (pt) * | 2010-03-03 | 2015-09-22 | Teva Pharma | tratamento de artrite reumatóide com a combinação de laquinimod e metotrexato |
BR112012022064A2 (pt) * | 2010-03-03 | 2015-09-08 | Teva Pharma | tratamento de artrite lúpica usando laquinimod |
ES2558556T3 (es) | 2010-03-03 | 2016-02-05 | Teva Pharmaceutical Industries Ltd. | Tratamiento de nefritis lúpica usando laquinimod |
PT2560993T (pt) | 2010-04-20 | 2024-09-16 | Genmab As | Proteínas contendo anticorpo heterodimérico fc e métodos para a produção das mesmas |
WO2012061074A1 (en) | 2010-10-25 | 2012-05-10 | Elan Pharmaceuticals, Inc. | METHODS FOR DETERMINING DIFFERENCES IN ALPHA-4 INTEGRIN ACTIVITY BY CORRELATING DIFFERENCES IN sVCAM AND/OR sMAdCAM LEVELS |
JP6184943B2 (ja) * | 2011-05-30 | 2017-08-23 | オートテリック エルエルシー | ポイント・オブ・ケア薬物動態プロフィールによる治療薬モニタリングおよび用量投与のための方法および組成物 |
HUE043339T2 (hu) | 2011-05-31 | 2019-08-28 | Biogen Ma Inc | Módszer a PML kockázatának megállapítására |
EP2766020A4 (en) | 2011-10-12 | 2015-04-01 | Teva Pharma | TREATMENT OF MULTIPLE SCLEROSIS BY COMBINING LAQUINIMOD AND FINGOLIMOD |
EP3674320A3 (en) | 2011-10-27 | 2020-08-12 | Genmab A/S | Production of heterodimeric proteins |
KR20140138694A (ko) | 2012-02-03 | 2014-12-04 | 테바 파마슈티컬 인더스트리즈 리미티드 | 최선의 항-TNFα 요법에 실패한 크론병 환자를 치료하기 위한 라퀴니모드의 용도 |
TW201400117A (zh) | 2012-06-05 | 2014-01-01 | Teva Pharma | 使用拉喹莫德治療眼發炎疾病 |
WO2014193804A1 (en) | 2013-05-28 | 2014-12-04 | Biogen Idec Ma Inc. | Method of assessing risk of pml |
EP3233907B1 (en) | 2014-12-19 | 2021-03-03 | Genmab A/S | Rodent bispecific heterodimeric proteins |
CN104865389B (zh) * | 2015-05-28 | 2017-06-06 | 卫生部北京医院 | 一种检测人血清杂合轻链抗体的方法及试剂盒 |
KR20180095719A (ko) * | 2016-01-11 | 2018-08-27 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | 키메라 단백질 및 면역요법 방법 |
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- 2007-03-02 MX MX2008011176A patent/MX2008011176A/es not_active Application Discontinuation
- 2007-03-02 CN CNA2007800158155A patent/CN101437541A/zh active Pending
- 2007-03-02 JP JP2008558307A patent/JP5504390B2/ja active Active
- 2007-03-02 BR BRPI0708392-0A patent/BRPI0708392A2/pt not_active IP Right Cessation
- 2007-03-02 SG SG201101499-0A patent/SG170058A1/en unknown
- 2007-03-02 CA CA002644110A patent/CA2644110A1/en not_active Abandoned
- 2007-03-02 US US11/713,000 patent/US20070231319A1/en not_active Abandoned
- 2007-03-02 KR KR1020087023464A patent/KR20080104343A/ko not_active Application Discontinuation
- 2007-03-02 AU AU2007224228A patent/AU2007224228B2/en active Active
- 2007-03-02 EP EP17206297.8A patent/EP3360900A1/en active Pending
- 2007-03-02 EP EP07751993.2A patent/EP1991267B1/en not_active Revoked
- 2007-03-02 RS RSP-2008/0391A patent/RS20080391A/sr unknown
- 2007-03-02 EA EA200801933A patent/EA016626B1/ru not_active IP Right Cessation
- 2007-03-02 WO PCT/US2007/005265 patent/WO2007103112A2/en active Application Filing
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2008
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- 2008-08-31 IL IL193775A patent/IL193775A/en not_active IP Right Cessation
- 2008-09-17 MA MA31249A patent/MA30287B1/fr unknown
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2012
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- 2012-12-03 JP JP2012264135A patent/JP5883377B2/ja active Active
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Also Published As
Publication number | Publication date |
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KR20080104343A (ko) | 2008-12-02 |
JP5504390B2 (ja) | 2014-05-28 |
WO2007103112A2 (en) | 2007-09-13 |
ZA200807346B (en) | 2009-09-30 |
IL193775A (en) | 2012-08-30 |
JP5883377B2 (ja) | 2016-03-15 |
SG170058A1 (en) | 2011-04-29 |
EP1991267A4 (en) | 2010-02-10 |
CN101437541A (zh) | 2009-05-20 |
AU2007224228B2 (en) | 2013-09-19 |
AU2007224228A1 (en) | 2007-09-13 |
JP2009529043A (ja) | 2009-08-13 |
EP3360900A1 (en) | 2018-08-15 |
BRPI0708392A2 (pt) | 2011-05-24 |
US11333670B2 (en) | 2022-05-17 |
EP1991267A2 (en) | 2008-11-19 |
US20200166521A1 (en) | 2020-05-28 |
JP2013067640A (ja) | 2013-04-18 |
WO2007103112A3 (en) | 2007-11-29 |
EP1991267B1 (en) | 2017-12-20 |
US20070231319A1 (en) | 2007-10-04 |
RS20080391A (en) | 2009-07-15 |
IL193775A0 (en) | 2011-08-01 |
EA200801933A1 (ru) | 2009-04-28 |
MA30287B1 (fr) | 2009-03-02 |
EA016626B1 (ru) | 2012-06-29 |
CA2644110A1 (en) | 2007-09-13 |
ES2663377T3 (es) | 2018-04-12 |
US20120177642A1 (en) | 2012-07-12 |
MX2008011176A (es) | 2008-09-10 |
US10466251B2 (en) | 2019-11-05 |
US20230082238A1 (en) | 2023-03-16 |
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