DK2661254T3 - Sprøjtetørring af vancomycin - Google Patents

Sprøjtetørring af vancomycin

Info

Publication number
DK2661254T3
DK2661254T3 DK12732323.6T DK12732323T DK2661254T3 DK 2661254 T3 DK2661254 T3 DK 2661254T3 DK 12732323 T DK12732323 T DK 12732323T DK 2661254 T3 DK2661254 T3 DK 2661254T3
Authority
DK
Denmark
Prior art keywords
spray drying
vancomycin
drying vancomycin
spray
drying
Prior art date
Application number
DK12732323.6T
Other languages
English (en)
Inventor
Cynthia Fragale
Daniel Brueck
Original Assignee
Hospira Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hospira Inc filed Critical Hospira Inc
Application granted granted Critical
Publication of DK2661254T3 publication Critical patent/DK2661254T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/14—Peptides containing saccharide radicals; Derivatives thereof, e.g. bleomycin, phleomycin, muramylpeptides or vancomycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK12732323.6T 2011-01-05 2012-01-04 Sprøjtetørring af vancomycin DK2661254T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161429844P 2011-01-05 2011-01-05
PCT/US2012/020160 WO2012094381A2 (en) 2011-01-05 2012-01-04 Spray drying vancomycin

Publications (1)

Publication Number Publication Date
DK2661254T3 true DK2661254T3 (da) 2017-11-06

Family

ID=46457949

Family Applications (1)

Application Number Title Priority Date Filing Date
DK12732323.6T DK2661254T3 (da) 2011-01-05 2012-01-04 Sprøjtetørring af vancomycin

Country Status (10)

Country Link
US (3) US8709310B2 (da)
EP (1) EP2661254B1 (da)
JP (1) JP5913367B2 (da)
CN (1) CN103429228B (da)
AU (1) AU2012204462A1 (da)
CA (1) CA2823628A1 (da)
DK (1) DK2661254T3 (da)
ES (1) ES2645769T3 (da)
TW (1) TW201309346A (da)
WO (1) WO2012094381A2 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITLO20110001A1 (it) * 2011-05-03 2012-11-04 Fisiopharma Srl Flaconi di vancomicina cloroidrata con stabilità migliorata
US8952105B2 (en) 2012-05-23 2015-02-10 Baker Hughes Incorporated Variable TG article, method of making, and use of same
CN104043104B (zh) * 2013-03-15 2018-07-10 浙江创新生物有限公司 含盐酸万古霉素的喷雾干粉及其工业化制备方法
EP3053907B1 (en) * 2013-09-30 2018-08-01 Daiichi Sankyo Company, Limited Selective production method for d-mannitol alpha-form crystal using spray-drying method
ES2903419T3 (es) 2014-03-14 2022-04-01 Azurity Pharmaceuticals Inc Composición y método para líquido oral de vancomicina
PT107568B (pt) * 2014-03-31 2018-11-05 Hovione Farm S A Processo de secagem por atomização para a produção de pós com propriedades melhoradas.
US20220184173A1 (en) * 2019-03-08 2022-06-16 Emphascience, Inc. Stable pharmaceutical formulations of peptide and protein drugs
CN114432339B (zh) * 2022-02-18 2023-05-26 重庆希尔安药业有限公司 一种聚乙二醇钠钾散及其制备方法

Family Cites Families (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2911036A (en) 1955-01-03 1959-11-03 Melvin E Lazar Spray-drying apparatus
DE3013839A1 (de) 1979-04-13 1980-10-30 Freunt Ind Co Ltd Verfahren zur herstellung einer aktivierten pharmazeutischen zusammensetzung
US4831015A (en) 1987-08-13 1989-05-16 American Cyanamid Company High potency biomass-free avoparcin and a method for its preparation
NZ232763A (en) 1989-03-06 1991-09-25 Lilly Co Eli Parenteral formulation comprising daptomycin with a buffer to maintain ph between 6.0 and 8.0
JPH03193735A (ja) * 1989-12-22 1991-08-23 Shionogi & Co Ltd グリコペプチド系抗生物質の安定化組成物
JPH04142149A (ja) 1990-10-02 1992-05-15 Canon Inc ファクシミリ装置
DE69233690T2 (de) 1991-07-02 2008-01-24 Nektar Therapeutics, San Carlos Abgabevorrichtung für nebelförmige Medikamente
US5785049A (en) 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
US6673335B1 (en) 1992-07-08 2004-01-06 Nektar Therapeutics Compositions and methods for the pulmonary delivery of aerosolized medicaments
US6582728B1 (en) 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
ATE220327T1 (de) 1992-09-29 2002-07-15 Inhale Therapeutic Syst Pulmonale abgabe von aktiven fragmenten des parathormons
US6051256A (en) 1994-03-07 2000-04-18 Inhale Therapeutic Systems Dispersible macromolecule compositions and methods for their preparation and use
GB9406769D0 (en) 1994-04-06 1994-05-25 Btr Plc Valve system
DK0758244T4 (da) 1994-05-06 2008-06-16 Pfizer Doseringsformer af azithromycin med styret frigivelse
CA2190502A1 (en) 1994-05-18 1995-11-23 Robert M. Platz Methods and compositions for the dry powder formulation of interferons
EP0782850A4 (en) 1994-10-13 1998-03-04 Wakamoto Pharma Co Ltd LYOPHILIZED PREPARATION FOR PRODUCING A REVERSIBLE THERMOGELING MEDICINAL WATER-BASED
IL116085A (en) 1994-12-16 1999-12-31 Ortho Pharma Corp Spray dried erythropoietin
SI9500039B (sl) * 1995-02-07 2002-02-28 Lek, Nov kombiniran postopek čiščenja Vankomicin hidroklorida
US7038219B2 (en) 1996-05-22 2006-05-02 Purepulse Technologies, Inc. Sterilization of packages and their contents using light
US6433344B1 (en) 1996-05-22 2002-08-13 Purepulse Technologies, Inc. Pulsed light sterilization of drinking water and drinking water containers
WO1998029141A1 (en) 1996-12-31 1998-07-09 Inhale Therapeutic Systems, Inc. Processes for spray drying solutions of hydrophobic drugs with hydrophilic excipients and compositions prepared by such processes
US20020039594A1 (en) 1997-05-13 2002-04-04 Evan C. Unger Solid porous matrices and methods of making and using the same
JPH115743A (ja) * 1997-06-16 1999-01-12 Kayaku:Kk バンコマイシン注射剤
JP4142149B2 (ja) 1997-07-10 2008-08-27 明治製菓株式会社 バンコマイシンの凍結乾燥製剤
US6413556B1 (en) * 1999-01-08 2002-07-02 Sky High, Llc Aqueous anti-apoptotic compositions
US6706283B1 (en) 1999-02-10 2004-03-16 Pfizer Inc Controlled release by extrusion of solid amorphous dispersions of drugs
EP1175390B1 (en) * 1999-04-05 2005-02-02 Emisphere Technologies, Inc. Disodium salts, monohydrates, and ethanol solvates
US6253463B1 (en) 1999-04-26 2001-07-03 Niro A/S Method of spray drying
US6223455B1 (en) 1999-05-03 2001-05-01 Acusphere, Inc. Spray drying apparatus and methods of use
US6395300B1 (en) 1999-05-27 2002-05-28 Acusphere, Inc. Porous drug matrices and methods of manufacture thereof
US6576224B1 (en) 1999-07-06 2003-06-10 Sinuspharma, Inc. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
ES2343124T3 (es) 1999-10-29 2010-07-23 Novartis Ag Composiciones de polvo seco con dispersabilidad mejorada.
EP1712222A3 (en) 1999-12-23 2012-06-20 Pfizer Products Inc. Pharmaceutical compositions providing enhanced drug concentrations
WO2001047542A1 (fr) * 1999-12-28 2001-07-05 Meiji Seika Kaisha, Ltd. Preparations de vancomycine
US6696412B1 (en) 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
US6730923B1 (en) 2000-05-05 2004-05-04 Purepulse Technologies, Inc. Transmissive conveyor for use in pulsed light sterilization
JP4081987B2 (ja) 2000-05-30 2008-04-30 株式会社村田製作所 金属粉末の製造方法，金属粉末，これを用いた導電性ペーストならびにこれを用いた積層セラミック電子部品
DE10036871A1 (de) 2000-07-28 2002-02-14 Pharmasol Gmbh Dispersionen zur Formulierung wenig oder schwer löslicher Wirkstoffe
JP2004506664A (ja) 2000-08-23 2004-03-04 ウォックハート・リミテッド 無水アジトロマイシンの製造法
ATE541564T1 (de) 2000-12-07 2012-02-15 Nycomed Gmbh Schnell zerfallende tablette mit einem säurelabilen wirkstoff
WO2002059145A1 (en) 2000-12-18 2002-08-01 Cubist Pharmaceuticals, Inc. Methods for preparing purified lipopeptides
US20060014674A1 (en) 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
KR20080036661A (ko) 2000-12-18 2008-04-28 큐비스트 파마슈티컬즈 인코포레이티드 정제된 리포펩티드의 제조 방법
FR2834212B1 (fr) 2001-12-27 2004-07-09 Besins Int Belgique Utilisation d'une poudre a liberation immediate dans des compositions pharmaceutiques et nutraceutiques
EP1469830A2 (en) 2002-02-01 2004-10-27 Pfizer Products Inc. Method for making homogeneous spray-dried solid amorphous drug dispersions using pressure nozzles
CN1309370C (zh) 2002-02-01 2007-04-11 辉瑞产品公司 使用改进的喷雾干燥设备制备均匀喷雾干燥的固体非晶形药物分散体的方法
US7258873B2 (en) 2002-04-11 2007-08-21 Medimmune Vaccines, Inc. Preservation of bioactive materials by spray drying
US7148211B2 (en) 2002-09-18 2006-12-12 Genzyme Corporation Formulation for lipophilic agents
WO2004044223A2 (en) * 2002-11-12 2004-05-27 Enzon Pharmaceuticals, Inc. Prodrugs of vancomycin with hydrolysis resistant polymer linkers
US20040121003A1 (en) 2002-12-19 2004-06-24 Acusphere, Inc. Methods for making pharmaceutical formulations comprising deagglomerated microparticles
US20050026813A1 (en) 2003-07-30 2005-02-03 Olstein Alan D. Antibiotic-metal complexes in the detection of gram-positive bacteria and other biological analytes
US20060292081A1 (en) 2003-09-15 2006-12-28 Vectura Limited Methods for preparing pharmaceutical compositions
US20050101547A1 (en) 2003-11-06 2005-05-12 Sadatrezaei Mohsen Stabilized azithromycin composition
EP1691786A1 (en) 2003-12-04 2006-08-23 Pfizer Products Inc. Multiparticulate compositions with improved stability
US7723306B2 (en) 2004-05-10 2010-05-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Spray-dried powder comprising at least one 1,4 O-linked saccharose-derivative and methods for their preparation
ATE529117T1 (de) 2004-07-02 2011-11-15 Wakamoto Pharma Co Ltd Medizinische zusammensetzung auf wasserbasis mit azithromycin und herstellungsverfahren dafür
US20060078622A1 (en) * 2004-08-13 2006-04-13 Emisphere Technologies, Inc. Pharmaceutical formulations containing microparticles or nanoparticles of a delivery agent
WO2006055950A1 (en) * 2004-11-18 2006-05-26 Nektar Therapeutics Pharmaceutical dry powder formulation on the basis particles comprising multiple active agents
CA2590687C (en) 2004-12-14 2013-09-10 Dr. Reddy's Laboratories Ltd. Process for preparing voriconazole
WO2006085337A1 (en) * 2005-02-14 2006-08-17 Venus Remedies Limited Parenteral combination therpy for infective conditions with drug resistant bacterium
US20060228251A1 (en) 2005-04-06 2006-10-12 Jagaji Holdings, Llc Pulsed high-intensity light sterilization
EP1877041A2 (en) 2005-04-29 2008-01-16 Cubist Pharmaceuticals, Inc. Therapeutic compositions
WO2007014393A2 (en) 2005-07-28 2007-02-01 Isp Investments Inc. Amorphous efavirenz and the production thereof
PT1973527E (pt) 2005-12-15 2010-01-04 Acusphere Inc Processos de produção de formulações farmacêuticas à base de partículas destinadas a administração parentérica
US7931859B2 (en) 2005-12-22 2011-04-26 Intelligent Hospital Systems Ltd. Ultraviolet sanitization in pharmacy environments
US7621921B2 (en) 2006-01-25 2009-11-24 Symmetry Medical, Inc Split thread orthopaedic implant impactor
CN1857716A (zh) * 2006-03-14 2006-11-08 浙江大学 注射用盐酸万古霉素及其制备方法
AR061889A1 (es) 2006-07-13 2008-10-01 Medichem Sa Proceso mejorado para la preparacion de voriconazol
PT2043610E (pt) 2006-07-21 2015-10-22 Bend Res Inc Secagem de partículas contendo fármacos
WO2008092057A2 (en) 2007-01-26 2008-07-31 Isp Investments Inc. Formulation process method to produce spray dried products
US8398732B2 (en) 2007-04-10 2013-03-19 Gea Process Engineering Inc. Process gas filtration
WO2009040818A1 (en) 2007-09-25 2009-04-02 Solubest Ltd Compositions comprising lipophilic active compounds and method for their preparation
US7795231B2 (en) 2007-10-04 2010-09-14 Insite Vision Incorporated Concentrated aqueous azalide formulations
US8125333B2 (en) 2008-06-04 2012-02-28 Triton Thalassic Technologies, Inc. Methods, systems and apparatus for monochromatic UV light sterilization
CN101613396B (zh) * 2008-06-26 2016-08-17 浙江医药股份有限公司新昌制药厂 无结晶型态盐酸万古霉素及其制备方法和用途、以及它的药物组合物
US20100049322A1 (en) 2008-08-19 2010-02-25 Warsaw Orthopedic, Inc. Osteochondral repair implants and methods
US20100057910A1 (en) 2008-09-02 2010-03-04 International Business Machines Corporation Concept for trusting client-side storage and distribution of asynchronous includes in an application server environment
CN101444510B (zh) 2008-12-31 2011-03-09 南京卡文迪许生物工程技术有限公司 含有伏立康唑的药物制剂及其制备方法
KR101101663B1 (ko) * 2009-01-13 2011-12-30 (주) 제노텍 반코마이신 습체의 정제방법
GB0902324D0 (en) 2009-02-12 2009-04-01 Powder Systems Ltd Improvements relating to valves
US8431539B2 (en) 2009-09-17 2013-04-30 Eagle Pharmaceuticals, Inc. Formulations of daptomycin
US20110124551A1 (en) 2009-11-23 2011-05-26 Eagle Pharmaceuticals, Inc. Formulations of daptomycin
FI2504353T4 (fi) 2009-11-23 2023-11-30 Cubist Pharmaceuticals Llc Lipopeptidikoostumukset ja vastaavat menetelmät

Also Published As

Publication number Publication date
US20140235530A1 (en) 2014-08-21
EP2661254A2 (en) 2013-11-13
US20150231197A1 (en) 2015-08-20
JP5913367B2 (ja) 2016-04-27
US9023258B2 (en) 2015-05-05
US8709310B2 (en) 2014-04-29
JP2014501781A (ja) 2014-01-23
CN103429228B (zh) 2016-10-26
WO2012094381A3 (en) 2013-06-20
ES2645769T3 (es) 2017-12-07
AU2012204462A1 (en) 2013-07-11
CN103429228A (zh) 2013-12-04
WO2012094381A2 (en) 2012-07-12
EP2661254A4 (en) 2015-01-28
US20130009330A1 (en) 2013-01-10
TW201309346A (zh) 2013-03-01
EP2661254B1 (en) 2017-08-02
US9763997B2 (en) 2017-09-19
CA2823628A1 (en) 2012-07-12

Similar Documents

Publication Publication Date Title
DK2788052T3 (da) Sprøjtemedbringer
BR112013023048A2 (pt) composto de guanidina
BR112013020337A2 (pt) secadora de roupas
DK2730310T3 (da) Applikator
DK2764405T3 (da) Kamera
FR2970970B1 (fr) Composition polyamide stabilisee
FI20115292A (fi) Termisesti ruiskutettu pinnoite
DK2661254T3 (da) Sprøjtetørring af vancomycin
DK2561020T3 (da) Coatingsammensætning
FI10412U1 (fi) Itsepuhdistuva suutin
DK2567019T3 (da) Fremgangsmåde til coating af tekstiler
BR112015006244A2 (pt) substrato revestido
FI20115336A (fi) Suihkutuspää
BR112013033512A2 (pt) poliamida ramificada
SMT201600280B (it) Calzino
DK2532220T3 (da) Marksprøjte
DK2788050T3 (da) Sprøjteholder
BR112014005895A2 (pt) revestimento biocida
FI20115952L (fi) Telapinnoite
AT12022U3 (de) Wäschetrockneranordnung
DE202012100323U8 (de) Spritzpistole
DE112013002592A5 (de) Beschichtungsmittel
AT12225U2 (de) Schubwendetrockner
FI20115666A0 (fi) Telapinnoite
DK2914385T3 (da) Fremgangmåde til belægning af objekter