BR112013023048A2 - composto de guanidina - Google Patents

composto de guanidina

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Publication number
BR112013023048A2
BR112013023048A2 BR112013023048A BR112013023048A BR112013023048A2 BR 112013023048 A2 BR112013023048 A2 BR 112013023048A2 BR 112013023048 A BR112013023048 A BR 112013023048A BR 112013023048 A BR112013023048 A BR 112013023048A BR 112013023048 A2 BR112013023048 A2 BR 112013023048A2
Authority
BR
Brazil
Prior art keywords
guanidine compound
guanidine
compound
Prior art date
Application number
BR112013023048A
Other languages
English (en)
Other versions
BR112013023048B1 (pt
Inventor
Daisuke Suzuki
Hiroyoshi Yamada
Hisashi Mihara
Kousei Yoshihara
Norio Seki
Susumu Yamaki
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Publication of BR112013023048A2 publication Critical patent/BR112013023048A2/pt
Publication of BR112013023048B1 publication Critical patent/BR112013023048B1/pt

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    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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