DK2588083T3 - Biomatrixscaffolds - Google Patents

Biomatrixscaffolds Download PDF

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Publication number
DK2588083T3
DK2588083T3 DK11801493.5T DK11801493T DK2588083T3 DK 2588083 T3 DK2588083 T3 DK 2588083T3 DK 11801493 T DK11801493 T DK 11801493T DK 2588083 T3 DK2588083 T3 DK 2588083T3
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Prior art keywords
cells
biomatrix
tissue
medium
scaffold
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DK11801493.5T
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Danish (da)
English (en)
Inventor
Lola Cynthia Mcadams Ried
Mitsuo Yamauchi
Cai-Bin Cui
Andrew Zhuang Wang
Michael Edward Werner
Yunfang Wang
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Univ North Carolina Chapel Hill
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3691—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by physical conditions of the treatment, e.g. applying a compressive force to the composition, pressure cycles, ultrasonic/sonication or microwave treatment, lyophilisation
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/067—Hepatocytes
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/067—Hepatocytes
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
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    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/28—Materials or treatment for tissue regeneration for liver reconstruction
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    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/20—Transition metals
    • C12N2500/24—Iron; Fe chelators; Transferrin
    • C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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    • C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
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    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
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    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24223—Virus like particles [VLP]
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    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24251—Methods of production or purification of viral material
    • C12N2770/24252—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Prostheses (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
DK11801493.5T 2010-07-02 2011-07-01 Biomatrixscaffolds DK2588083T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36093910P 2010-07-02 2010-07-02
PCT/US2011/042805 WO2012003450A2 (en) 2010-07-02 2011-07-01 Biomatrix scaffolds

Publications (1)

Publication Number Publication Date
DK2588083T3 true DK2588083T3 (en) 2017-06-19

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Family Applications (2)

Application Number Title Priority Date Filing Date
DK11801493.5T DK2588083T3 (en) 2010-07-02 2011-07-01 Biomatrixscaffolds
DK11801504.9T DK2588027T3 (en) 2010-07-02 2011-07-01 Biomatrix scaffolds for industrial scale distribution

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK11801504.9T DK2588027T3 (en) 2010-07-02 2011-07-01 Biomatrix scaffolds for industrial scale distribution

Country Status (11)

Country Link
US (7) US9102913B2 (enExample)
EP (6) EP3603622B1 (enExample)
JP (7) JP2013539960A (enExample)
CN (4) CN105713868A (enExample)
DK (2) DK2588083T3 (enExample)
ES (6) ES2879246T3 (enExample)
HU (2) HUE032727T2 (enExample)
LT (2) LT2588083T (enExample)
PL (2) PL2588027T3 (enExample)
PT (2) PT2588083T (enExample)
WO (2) WO2012003450A2 (enExample)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2588083T3 (en) * 2010-07-02 2017-06-19 Univ North Carolina Chapel Hill Biomatrixscaffolds
NL2009145C2 (en) * 2012-07-06 2014-01-07 Xeltis B V Implant.
CN103536967B (zh) * 2012-07-10 2016-04-13 上海微创医疗器械（集团）有限公司 一种制备细胞外基质支架材料的脱细胞方法
US9533013B2 (en) 2013-03-13 2017-01-03 University Of North Carolina At Chapel Hill Method of treating pancreatic and liver conditions by endoscopic-mediated (or laparoscopic-mediated) transplantation of stem cells into/onto bile duct walls of particular regions of the biliary tree
PT2968418T (pt) * 2013-03-15 2024-01-11 Nutech Medical Inc Preparações derivadas de materiais placentários e produção e utilização das mesmas
KR102278652B1 (ko) * 2013-03-15 2021-07-19 미로매트릭스 메디칼 인크. 섬 세포 재세포화를 위한 관류 탈세포화된 간의 용도
PL2983616T3 (pl) * 2013-04-08 2019-05-31 Regentys Corp Sposób i kompozycja do leczenia nieswoistego zapalenia jelit bez kolektomii
US20150037436A1 (en) 2013-07-30 2015-02-05 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
CN103432627B (zh) * 2013-08-26 2015-03-25 北京瑞健高科生物科技有限公司 一种制备动物脱细胞组织基质材料的方法及其制备的组织基质材料
WO2015148832A1 (en) 2014-03-27 2015-10-01 Salk Institute For Biological Studies Compositions and methods for treating type 1 and type 2 diabetes and related disorders
GB201409858D0 (en) * 2014-06-03 2014-07-16 Ucl Business Plc Human liver scaffolds
CN104288837B (zh) * 2014-09-11 2016-04-13 杨淑珍 一种脱细胞真皮基质及其制备方法和用途
CA2977520A1 (en) 2015-02-27 2016-09-01 Salk Institute For Biological Studies Reprogramming progenitor compositions and methods of use therefore
CN104928241B (zh) * 2015-03-27 2018-04-13 北京康爱瑞浩生物科技股份有限公司 一种增强型nk细胞的活化方法及细胞制备方法
WO2016200340A1 (en) * 2015-06-12 2016-12-15 Agency For Science, Technology And Research Derivation of hepatic stem cells and mature liver cell types and uses thereof
US10912864B2 (en) 2015-07-24 2021-02-09 Musculoskeletal Transplant Foundation Acellular soft tissue-derived matrices and methods for preparing same
US11052175B2 (en) 2015-08-19 2021-07-06 Musculoskeletal Transplant Foundation Cartilage-derived implants and methods of making and using same
CN106884002B (zh) * 2015-12-15 2021-03-19 上海市针灸经络研究所 一种稳定的结肠上皮细胞培养方法
CN105833353B (zh) * 2016-05-09 2018-04-20 拜欧迪赛尔（北京）生物科技有限公司 一种生物工程脱细胞真皮基质的制备及用途
US20170369849A1 (en) * 2016-05-11 2017-12-28 The University Of North Carolina At Chapel Hill Compositions and methods for bioengineered tissues
WO2017205511A1 (en) * 2016-05-25 2017-11-30 Salk Institute For Biological Studies Compositions and methods for organoid generation and disease modeling
US20190234937A1 (en) * 2016-07-12 2019-08-01 The University Of North Carolina At Chapel Hill Biomatrix scaffolds for use in diagnosing and modeling cancer
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