DK2569632T3 - Gærcellevægkomponenter og detektering deraf - Google Patents

Gærcellevægkomponenter og detektering deraf Download PDF

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Publication number
DK2569632T3
DK2569632T3 DK11781379.0T DK11781379T DK2569632T3 DK 2569632 T3 DK2569632 T3 DK 2569632T3 DK 11781379 T DK11781379 T DK 11781379T DK 2569632 T3 DK2569632 T3 DK 2569632T3
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Denmark
Prior art keywords
glucan
feed
yeast
sample
mycosorb
Prior art date
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DK11781379.0T
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English (en)
Inventor
Colm Moran
Stefan Kwiatkowski
Alexandros Yiannikouris
Ursula Anne Thielen
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Alltech Inc
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Publication of DK2569632T3 publication Critical patent/DK2569632T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56961Plant cells or fungi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/14Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from fungi, algea or lichens
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/37Assays involving biological materials from specific organisms or of a specific nature from fungi
    • G01N2333/39Assays involving biological materials from specific organisms or of a specific nature from fungi from yeasts
    • G01N2333/395Assays involving biological materials from specific organisms or of a specific nature from fungi from yeasts from Saccharomyces
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/12Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar
    • G01N2400/14Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar alpha-D-Glucans, i.e. having alpha 1,n (n=3,4,6) linkages between saccharide units, e.g. pullulan
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/12Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar
    • G01N2400/24Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar beta-D-Glucans, i.e. having beta 1,n (n=3,4,6) linkages between saccharide units, e.g. xanthan

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Public Health (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Botany (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)

Claims (3)

  1. PAT E NT K RAV
    1. Fremgangsmåde til detektering af en gærcellevægkomponent i en prøve, omfattende: - at tilvejebringe en næringsmiddel- eller foderprøve valgt blandt gruppen bestående af husdyrsfoder, kæledyrsfoder, TMR (Total Mixed Ration), grøntfoder, foderpiller, kraftfoder, foderforblandingsbiprodukt, korn, bærme, melasse, fiber, foder, græs, hø, kerne, blade, mel, opløseligt foder og ekstrakter deraf; - at foretage en prøvning, der omfatter at bringe et primært antistof, der kan binde til et antigen valgt blandt gruppen bestående af (1^4)-a-D-glucan, (1^6)-p-D-glucan og (1^4)-α-/(1^6)-β-Ο-glucan, i kontakt med prøven under betingelser, således at det primære antistof danner et kompleks med antigenet, hvis det findes; og at anvende et andet antistof til at detektere det primære antistof-antigenkompleks, hvor detekteringen af det primære antistof-antigenkompleks giver en indikation af forekomsten af gærcellevægkomponenten i prøven.
  2. 2. Fremgangsmåde ifølge krav 1, hvor fremgangsmåden omfatter at opnå ekstraktet fra prøven ved anvendelse af organisk opløsningsmiddel og syre.
  3. 3. Fremgangsmåde ifølge krav 1, hvor fremgangsmåden omfatter at opnå ekstraktet fra prøven ved anvendelse af dimethylsulfoxid og saltsyre.
DK11781379.0T 2010-05-14 2011-05-13 Gærcellevægkomponenter og detektering deraf DK2569632T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33499510P 2010-05-14 2010-05-14
PCT/US2011/036518 WO2011143613A1 (en) 2010-05-14 2011-05-13 Yeast cell wall components and detection thereof

Publications (1)

Publication Number Publication Date
DK2569632T3 true DK2569632T3 (da) 2018-11-19

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DK11781379.0T DK2569632T3 (da) 2010-05-14 2011-05-13 Gærcellevægkomponenter og detektering deraf

Country Status (25)

Country Link
US (1) US20110281283A1 (da)
EP (1) EP2569632B1 (da)
JP (1) JP2013532276A (da)
KR (1) KR101440818B1 (da)
CN (1) CN102939537B (da)
AU (1) AU2011252840B2 (da)
BR (1) BR112012030535B1 (da)
CA (1) CA2798328A1 (da)
CL (1) CL2012003165A1 (da)
CO (1) CO6660470A2 (da)
DK (1) DK2569632T3 (da)
EA (1) EA201291091A1 (da)
ES (1) ES2691260T3 (da)
IL (1) IL222789A (da)
MX (1) MX2012013170A (da)
MY (1) MY173081A (da)
NZ (2) NZ623714A (da)
PE (1) PE20130526A1 (da)
PL (1) PL2569632T3 (da)
PT (1) PT2569632T (da)
RS (1) RS57937B1 (da)
SG (1) SG185485A1 (da)
UA (1) UA103283C2 (da)
WO (1) WO2011143613A1 (da)
ZA (1) ZA201208200B (da)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3119901T3 (da) 2014-03-21 2021-07-26 Dsm Ip Assets Bv Fremgangsmåde til behanlding af gærcellevægge med en laminaripentaose-producerende beta-1,3-glucanase
US12019071B2 (en) * 2015-05-08 2024-06-25 Waters Technologies Corporation Composition and methods for extracting mycotoxins
CN105137084B (zh) * 2015-08-20 2016-09-28 厦门大学 一种葡聚糖的夹心酶联免疫吸附测定方法
JP6530846B1 (ja) * 2018-10-09 2019-06-12 アサヒグループホールディングス株式会社 免疫賦活剤及び感染予防方法
CN114196216B (zh) * 2021-12-27 2023-01-06 杭州靡特洛新材料科技有限公司 一种基于酒糟废弃物的全生物降解热塑水溶膜及其制备方法和应用
CN117126753B (zh) * 2023-10-26 2024-04-09 中粮营养健康研究院有限公司 产多糖酿酒酵母及其在龙眼葡萄酒酿造中的应用

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WO1994013804A1 (en) 1992-12-04 1994-06-23 Medical Research Council Multivalent and multispecific binding proteins, their manufacture and use
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JP5054425B2 (ja) * 2007-05-07 2012-10-24 尚仁 大野 抗β−1,6−グルカン・モノクローナル抗体
CN101353383B (zh) * 2008-09-17 2010-12-08 山东京博控股发展有限公司 水溶性酵母β-葡聚糖及其制备方法
CN101403749B (zh) * 2008-11-17 2012-11-07 北京大学 通过葡聚糖特异性抗体辅助诊断自身免疫性疾病的试剂盒

Also Published As

Publication number Publication date
ZA201208200B (en) 2014-01-29
EP2569632A1 (en) 2013-03-20
MX2012013170A (es) 2013-01-17
CL2012003165A1 (es) 2013-09-23
MY173081A (en) 2019-12-25
KR101440818B1 (ko) 2014-11-03
UA103283C2 (ru) 2013-09-25
IL222789A (en) 2016-09-29
EA201291091A1 (ru) 2013-05-30
RS57937B1 (sr) 2019-01-31
US20110281283A1 (en) 2011-11-17
NZ603340A (en) 2014-04-30
KR20130038863A (ko) 2013-04-18
CN102939537B (zh) 2016-09-14
WO2011143613A1 (en) 2011-11-17
IL222789A0 (en) 2012-12-31
PE20130526A1 (es) 2013-05-05
ES2691260T3 (es) 2018-11-26
BR112012030535A2 (pt) 2018-01-16
PL2569632T3 (pl) 2019-02-28
CO6660470A2 (es) 2013-04-30
NZ623714A (en) 2015-10-30
SG185485A1 (en) 2012-12-28
CN102939537A (zh) 2013-02-20
JP2013532276A (ja) 2013-08-15
AU2011252840B2 (en) 2014-07-03
EP2569632A4 (en) 2014-01-08
PT2569632T (pt) 2018-11-20
CA2798328A1 (en) 2011-11-17
BR112012030535B1 (pt) 2021-06-01
EP2569632B1 (en) 2018-08-15

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