DK2531492T3 - 1,2,4-triazin-4-amine derivatives - Google Patents

1,2,4-triazin-4-amine derivatives Download PDF

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Publication number
DK2531492T3
DK2531492T3 DK11704571.6T DK11704571T DK2531492T3 DK 2531492 T3 DK2531492 T3 DK 2531492T3 DK 11704571 T DK11704571 T DK 11704571T DK 2531492 T3 DK2531492 T3 DK 2531492T3
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amine
triazine
phenyl
triazin
pyridin
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DK11704571.6T
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Danish (da)
English (en)
Inventor
Miles Stuart Congreve
Stephen Philippe Andrews
Jonathan Stephen Mason
Christine Mary Richardson
Giles Albert Brown
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Heptares Therapeutics Ltd
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    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
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    • C07D253/06—1,2,4-Triazines
    • C07D253/065—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members
    • C07D253/07—1,2,4-Triazines having three double bonds between ring members or between ring members and non-ring members with hetero atoms, or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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DK11704571.6T 2010-02-05 2011-02-07 1,2,4-triazin-4-amine derivatives DK2531492T3 (en)

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US30206010P 2010-02-05 2010-02-05
US38176410P 2010-09-10 2010-09-10
PCT/EP2011/051755 WO2011095625A1 (en) 2010-02-05 2011-02-07 1,2,4-triazine-4-amine derivatives

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EP (1) EP2531492B1 (https=)
JP (1) JP5914361B2 (https=)
KR (2) KR101993867B1 (https=)
CN (1) CN102822150B (https=)
AU (1) AU2011212430B2 (https=)
BR (1) BR112012019540B1 (https=)
CA (1) CA2789279C (https=)
CY (1) CY1117780T1 (https=)
DK (1) DK2531492T3 (https=)
ES (1) ES2579949T3 (https=)
HR (1) HRP20160636T1 (https=)
HU (1) HUE028640T2 (https=)
IL (1) IL221160A (https=)
MX (1) MX352415B (https=)
MY (1) MY180024A (https=)
PL (1) PL2531492T3 (https=)
PT (1) PT2531492T (https=)
RU (1) RU2625791C2 (https=)
SG (1) SG183146A1 (https=)
SI (1) SI2531492T1 (https=)
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SI2531492T1 (sl) * 2010-02-05 2016-08-31 Heptares Therapeutics Limited Derivati 1,2,4-triazin-4-amina
SG10201701547VA (en) 2011-02-23 2017-03-30 Massachusetts Inst Technology Water soluble membrane proteins and methods for the preparation and use thereof
CN104341386A (zh) * 2013-07-23 2015-02-11 中国科学院上海药物研究所 一类芳基杂环小分子化合物、其衍生物及其制备方法和用途
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