DK2352508T3 - Muc-1 cytoplasmisk domæne-peptider som inhibitorer af cancer - Google Patents

Muc-1 cytoplasmisk domæne-peptider som inhibitorer af cancer

Info

Publication number
DK2352508T3
DK2352508T3 DK09740811.6T DK09740811T DK2352508T3 DK 2352508 T3 DK2352508 T3 DK 2352508T3 DK 09740811 T DK09740811 T DK 09740811T DK 2352508 T3 DK2352508 T3 DK 2352508T3
Authority
DK
Denmark
Prior art keywords
muc
cytoplasmic domain
domain peptides
cancer inhibitors
inhibitors
Prior art date
Application number
DK09740811.6T
Other languages
Danish (da)
English (en)
Inventor
Donald W Kufe
Surender Kharbanda
Original Assignee
Dana Farber Cancer Inst Inc
Genus Oncology Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dana Farber Cancer Inst Inc, Genus Oncology Llc filed Critical Dana Farber Cancer Inst Inc
Application granted granted Critical
Publication of DK2352508T3 publication Critical patent/DK2352508T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4727Mucins, e.g. human intestinal mucin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A61K38/1735Mucins, e.g. human intestinal mucin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64Cyclic peptides containing only normal peptide links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK09740811.6T 2008-10-17 2009-10-16 Muc-1 cytoplasmisk domæne-peptider som inhibitorer af cancer DK2352508T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10638008P 2008-10-17 2008-10-17
US17710909P 2009-05-11 2009-05-11
PCT/US2009/061051 WO2010045586A2 (en) 2008-10-17 2009-10-16 Muc-1 cytoplasmic domain peptides as inhibitors of cancer

Publications (1)

Publication Number Publication Date
DK2352508T3 true DK2352508T3 (da) 2014-04-28

Family

ID=42046194

Family Applications (1)

Application Number Title Priority Date Filing Date
DK09740811.6T DK2352508T3 (da) 2008-10-17 2009-10-16 Muc-1 cytoplasmisk domæne-peptider som inhibitorer af cancer

Country Status (19)

Country Link
US (3) US8524669B2 (https=)
EP (2) EP2727601B1 (https=)
JP (2) JP5657549B2 (https=)
KR (1) KR101689408B1 (https=)
CN (1) CN102245632B (https=)
AU (1) AU2009305550B2 (https=)
BR (1) BRPI0920360A2 (https=)
CA (1) CA2741065C (https=)
DE (1) DE09740811T9 (https=)
DK (1) DK2352508T3 (https=)
ES (1) ES2395028T3 (https=)
IL (1) IL212383A (https=)
MX (1) MX2011004082A (https=)
NZ (1) NZ592537A (https=)
PL (1) PL2352508T3 (https=)
PT (1) PT2352508E (https=)
RU (1) RU2539832C2 (https=)
WO (1) WO2010045586A2 (https=)
ZA (1) ZA201103150B (https=)

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JP5702371B2 (ja) 2009-05-27 2015-04-15 デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド Muc1のアンタゴニストを使用した、炎症の阻害
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US8907054B2 (en) * 2011-08-08 2014-12-09 Marquette University Dpy-30 binding peptides
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JP6153526B2 (ja) 2011-09-06 2017-06-28 エージェンシー フォー サイエンス,テクノロジー アンド リサーチ ポリペプチドワクチン
US8754124B2 (en) 2011-11-23 2014-06-17 Board Of Regents, The University Of Texas System Oligo-benzamide compounds and their use in treating cancers
WO2013078288A1 (en) * 2011-11-23 2013-05-30 The Board Of Regents Of The University Of Texas System Oligo-benzamide compounds for use in treating cancers
US9044421B2 (en) 2012-03-28 2015-06-02 Genus Oncology, Llc Treating MUC1-expressing cancers with combination therapies
US9789156B2 (en) 2013-03-11 2017-10-17 Dana-Farber Cancer Institute, Inc. Combination anti-human epidermal growth factor receptor 2 (anti-HER2) cancer therapy using mucin 1 (MUC1) peptides and hemotherapeutics
WO2014164395A1 (en) * 2013-03-11 2014-10-09 Dana-Farber Cancer Institute, Inc. Combination anti-estrogen receptor cancer therapy using muc1 peptides and chemotherapeutics
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Also Published As

Publication number Publication date
EP2727601A1 (en) 2014-05-07
US9546201B2 (en) 2017-01-17
JP2015096513A (ja) 2015-05-21
WO2010045586A3 (en) 2011-01-13
RU2539832C2 (ru) 2015-01-27
ES2395028T3 (es) 2014-05-30
BRPI0920360A2 (pt) 2021-03-02
CA2741065A1 (en) 2010-04-22
JP6030622B2 (ja) 2016-11-24
CN102245632A (zh) 2011-11-16
MX2011004082A (es) 2011-10-14
HK1160795A1 (en) 2012-08-17
CN102245632B (zh) 2018-10-12
ZA201103150B (en) 2014-12-23
IL212383A0 (en) 2011-06-30
AU2009305550B2 (en) 2014-06-12
EP2352508B1 (en) 2014-04-02
WO2010045586A2 (en) 2010-04-22
PL2352508T3 (pl) 2014-09-30
US20100125055A1 (en) 2010-05-20
WO2010045586A8 (en) 2011-08-04
US20150152152A1 (en) 2015-06-04
US8524669B2 (en) 2013-09-03
JP5657549B2 (ja) 2015-01-21
ES2395028T1 (es) 2013-02-07
IL212383A (en) 2017-10-31
DE09740811T1 (de) 2012-03-22
EP2352508A2 (en) 2011-08-10
AU2009305550A1 (en) 2010-04-22
NZ592537A (en) 2012-07-27
KR101689408B1 (ko) 2016-12-23
RU2011119606A (ru) 2012-11-27
US8957185B2 (en) 2015-02-17
KR20110093801A (ko) 2011-08-18
PT2352508E (pt) 2014-05-26
CA2741065C (en) 2017-04-25
US20120172312A1 (en) 2012-07-05
EP2727601B1 (en) 2018-06-13
DE09740811T9 (de) 2013-10-31
JP2012505922A (ja) 2012-03-08

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