DK2316456T3 - Sammensætninger til at påvirke vægttab omfattende en opioidantagonist og bupropion - Google Patents
Sammensætninger til at påvirke vægttab omfattende en opioidantagonist og bupropion Download PDFInfo
- Publication number
- DK2316456T3 DK2316456T3 DK10185782.9T DK10185782T DK2316456T3 DK 2316456 T3 DK2316456 T3 DK 2316456T3 DK 10185782 T DK10185782 T DK 10185782T DK 2316456 T3 DK2316456 T3 DK 2316456T3
- Authority
- DK
- Denmark
- Prior art keywords
- compound
- composition
- individual
- opioid
- naltrexone
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
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- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Magnetic Ceramics (AREA)
- Compositions Of Oxide Ceramics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Dental Preparations (AREA)
Claims (12)
1. Sammensætning til anvendelse i en fremgangsmåde til at påvirke vægttab eller at behandle fedme omfattende en første forbindelse og en anden forbindelse hvor den første forbindelse er en opioidantagonist og den anden forbindelse er bupropion.
2. Sammensætning til anvendelse ifølge krav 1 hvor opioidantagonisten antagoniserer en opioidreceptor valgt fra en μ-opioidreceptor- (MOP-R) antagonist, en κ-opioidreceptor og en δ-opioidreceptor.
3. Sammensætning til anvendelse ifølge krav 2, hvor opioidantagonisten er en μ-opioidreceptor- (MOP-R) antagonist.
4. Sammensætning til anvendelse ifølge krav 1, hvor opioidantagonisten er valgt fra gruppen bestående af alvimopan, norbinaltorphimin, nalmefen, naloxon, naltrexon, methylnaltrexon og nalorphin, og farmaceutisk acceptable salte deraf.
5. Sammensætning til anvendelse ifølge krav 1, hvor opioidantagonisten er naltrexon.
6. Sammensætning til anvendelse ifølge krav 5, hvor bupropionen er en bupropion med langvarig frigivelse.
7. Sammensætning til anvendelse ifølge krav 1, hvor sammensætningen er en lægemiddelkombination, hvilken lægemiddelkombination omfatter bupropion med langvarig frigivelse eller et farmaceutisk acceptabelt salt deraf i en dosis på 30 mg til 300 mg, og naltrexon eller et farmaceutisk acceptabelt salt deraf i en dosis på 5 mg til 50 mg, hvor anvendelsen er behandlingen af overvægt med oral indgivelse af lægemiddelkombinationen.
8. Sammensætning til anvendelse ifølge krav 1, hvor sammensætningen er en lægemiddelkombination, hvilken lægemiddelkombination omfatter bupropion med langvarig frigivelse eller et farmaceutisk acceptabelt salt deraf i en dosis på 30 mg til 300 mg, og naltrexon eller et farmaceutisk acceptabelt salt deraf i en dosis på 5 mg til 50 mg, hvor anvendelsen er behandlingen af fedme med oral indgivelse af lægemiddelkombinationen.
9. Sammensætning til anvendelse ifølge krav 7 eller 8, hvor sammensætningen omfatter bupropion med langvarig frigivelse i en dosis på 50 mg, 60 mg, 70 mg, 80 mg, 90 mg, 100 mg, 110 mg, 120 mg, 130 mg, 140 mg eller 150 mg.
10. Sammensætning til anvendelse ifølge et hvilket som helst af kravene 7-9, hvor sammensætningen omfatter naltrexon i en dosis på 5 mg, 10 mg, 15 mg, 20 mg eller 25 mg.
11. Sammensætning til anvendelse ifølge et hvilket som helst af de foregående krav, hvor fremgangsmåden til at påvirke vægttab eller at behandle fedme udføres på et individ med et kropsmasseindeks på mere end 25.
12. Sammensætning til anvendelse ifølge et hvilket som helst af de foregående krav, hvor fremgangsmåden til at påvirke vægttab eller at behandle fedme udføres på et individ med et kropsmasseindeks på mere end 30.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46683803P | 2003-04-29 | 2003-04-29 | |
EP07116330A EP1870096A3 (en) | 2003-04-29 | 2004-04-21 | Compositions for affecting weight loss |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2316456T3 true DK2316456T3 (da) | 2017-09-11 |
Family
ID=33418430
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK10185782.9T DK2316456T3 (da) | 2003-04-29 | 2004-04-21 | Sammensætninger til at påvirke vægttab omfattende en opioidantagonist og bupropion |
DK04760321T DK1617832T3 (da) | 2003-04-29 | 2004-04-21 | Præparater til påvirkning af vægttab |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK04760321T DK1617832T3 (da) | 2003-04-29 | 2004-04-21 | Præparater til påvirkning af vægttab |
Country Status (21)
Country | Link |
---|---|
US (10) | US7375111B2 (da) |
EP (3) | EP1617832B1 (da) |
JP (1) | JP4343948B2 (da) |
KR (1) | KR101167579B1 (da) |
CN (1) | CN1784221B (da) |
AT (1) | ATE388698T1 (da) |
AU (2) | AU2004233846B2 (da) |
CA (1) | CA2522708C (da) |
DE (1) | DE602004012403T2 (da) |
DK (2) | DK2316456T3 (da) |
ES (3) | ES2639579T3 (da) |
HK (2) | HK1088850A1 (da) |
HU (2) | HUE034290T2 (da) |
IL (3) | IL171519A (da) |
MX (1) | MXPA05011557A (da) |
PL (2) | PL1617832T3 (da) |
PT (2) | PT1617832E (da) |
RU (1) | RU2350327C2 (da) |
SI (1) | SI2316456T1 (da) |
TW (1) | TWI356701B (da) |
WO (1) | WO2004096201A1 (da) |
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