DK2289D0 - Monoklonale antistoffer samt deres fremstilling og anvendelse - Google Patents

Monoklonale antistoffer samt deres fremstilling og anvendelse

Info

Publication number
DK2289D0
DK2289D0 DK002289A DK2289A DK2289D0 DK 2289 D0 DK2289 D0 DK 2289D0 DK 002289 A DK002289 A DK 002289A DK 2289 A DK2289 A DK 2289A DK 2289 D0 DK2289 D0 DK 2289D0
Authority
DK
Denmark
Prior art keywords
antibodies
preparation
derivatives
monoclonal antibodies
therapy
Prior art date
Application number
DK002289A
Other languages
English (en)
Other versions
DK2289A (da
DK172440B1 (da
Inventor
Franz Buchegger
Jean-Pierre Mach
Original Assignee
Franz Buchegger
Res Corp Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Franz Buchegger, Res Corp Technologies Inc filed Critical Franz Buchegger
Publication of DK2289D0 publication Critical patent/DK2289D0/da
Publication of DK2289A publication Critical patent/DK2289A/da
Application granted granted Critical
Publication of DK172440B1 publication Critical patent/DK172440B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3007—Carcino-embryonic Antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK198900022A 1988-01-05 1989-01-04 Monoklonale antistoffer og derivater deraf, fremgangsmåde til deres fremstilling, hybridomacellelinie og fremgangsmåde til DK172440B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8800078 1988-01-05
GB888800078A GB8800078D0 (en) 1988-01-05 1988-01-05 Novel antibodies

Publications (3)

Publication Number Publication Date
DK2289D0 true DK2289D0 (da) 1989-01-04
DK2289A DK2289A (da) 1989-07-06
DK172440B1 DK172440B1 (da) 1998-07-27

Family

ID=10629465

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198900022A DK172440B1 (da) 1988-01-05 1989-01-04 Monoklonale antistoffer og derivater deraf, fremgangsmåde til deres fremstilling, hybridomacellelinie og fremgangsmåde til

Country Status (12)

Country Link
US (1) US5047507A (da)
EP (1) EP0323805B1 (da)
JP (1) JPH025893A (da)
AT (1) ATE101202T1 (da)
AU (1) AU619232B2 (da)
CA (1) CA1315219C (da)
DE (1) DE3887675T2 (da)
DK (1) DK172440B1 (da)
ES (1) ES2061730T3 (da)
GB (1) GB8800078D0 (da)
IE (1) IE62439B1 (da)
PT (1) PT89385B (da)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0617127A1 (en) * 1987-12-31 1994-09-28 Tanox Biosystems, Inc. Antigenic epitopes on B cell-bound IgE Immunoglobulins
GB8800077D0 (en) * 1988-01-05 1988-02-10 Ciba Geigy Ag Novel chimeric antibodies
US5843708A (en) * 1988-01-05 1998-12-01 Ciba-Geigy Corporation Chimeric antibodies
WO1991007418A1 (en) * 1989-11-13 1991-05-30 Xoma Corporation Chimeric mouse-human a10 antibody with specificity to a human tumor cell antigen
GB9014932D0 (en) * 1990-07-05 1990-08-22 Celltech Ltd Recombinant dna product and method
US5661016A (en) * 1990-08-29 1997-08-26 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
AU3657693A (en) * 1992-01-29 1993-09-01 Regents Of The University Of California, The Carcinoma associated antigen (SK1) monoclonal antibodies against SK1, methods of producing these antibodies and use therfor
US5648078A (en) * 1992-02-14 1997-07-15 Suntory Limited Method for inhibiting metastasis of colon cancer to the liver
CA2102294A1 (en) * 1992-03-10 1993-09-11 Jose L. Millan Recombinant calf intestinal alkaline phosphatase
US5502037A (en) * 1993-07-09 1996-03-26 Neuromed Technologies, Inc. Pro-cytotoxic drug conjugates for anticancer therapy
US5874540A (en) 1994-10-05 1999-02-23 Immunomedics, Inc. CDR-grafted type III anti-CEA humanized mouse monoclonal antibodies
ATE223060T1 (de) * 1994-11-28 2002-09-15 Abbott Lab Stabile wässrige steroid-standardproben für immuntests
US5648268A (en) * 1994-12-06 1997-07-15 Ibm Corporation Radionuclide exchange detection of ultra trace ionic impurities in water
US6207805B1 (en) 1997-07-18 2001-03-27 University Of Iowa Research Foundation Prostate cell surface antigen-specific antibodies
US6828157B1 (en) 1999-05-04 2004-12-07 Dan A. Pankowsky Products and methods for single parameter and multiparameter phenotyping of cells
US6682940B2 (en) * 1999-05-04 2004-01-27 Dan A. Pankowsky Products and methods for single parameter and multiparameter phenotyping of cells
US6774209B1 (en) * 2000-04-03 2004-08-10 Dyax Corp. Binding peptides for carcinoembryonic antigen (CEA)
US20020139628A1 (en) * 2001-03-30 2002-10-03 Wen-Chen Chang Retractable handle assembly
JP4638735B2 (ja) * 2002-06-24 2011-02-23 タフツ ユニバーシティー 絹糸生体材料およびその使用方法
JP4790413B2 (ja) 2002-10-08 2011-10-12 イミューノメディクス、インコーポレイテッド 抗体療法
US7842780B2 (en) 2003-01-07 2010-11-30 Trustees Of Tufts College Silk fibroin materials and use thereof
WO2005012606A2 (en) 2003-04-10 2005-02-10 Tufts University Concentrated aqueous silk fibroin solution and use thereof
WO2005000483A1 (en) * 2003-06-06 2005-01-06 Tufts University Method for forming inorganic coatings
JP2006214765A (ja) * 2005-02-01 2006-08-17 Bml Inc ヒトＡｐｏＡ−Ｖ蛋白質に対する抗体、及び、当該抗体を用いたヒトＡｐｏＡ−Ｖ蛋白質定量測定系
JP2010522583A (ja) 2007-02-27 2010-07-08 トラスティーズ オブ タフツ カレッジ 組織工学的に作製された絹製臓器
AU2008260156B2 (en) 2007-05-29 2013-10-31 Trustees Of Tufts College Method for silk fibroin gelation using sonication
WO2009100280A2 (en) * 2008-02-07 2009-08-13 Trustees Of Tufts College 3-dimensional silk hydroxyapatite compositions
US9040073B2 (en) * 2008-05-15 2015-05-26 Trustees Of Tufts College Silk polymer-based adenosine release: therapeutic potential for epilepsy
US8501172B2 (en) * 2008-09-26 2013-08-06 Trustees Of Tufts College pH-induced silk gels and uses thereof
US20110223153A1 (en) * 2008-10-09 2011-09-15 Trustees Of Tufts College Modified silk films containing glycerol
CA2812635A1 (en) 2009-07-14 2011-01-20 Trustees Of Tufts College Electrospun silk material systems for wound healing
JP2013506058A (ja) 2009-09-28 2013-02-21 タフツ ユニバーシティー／トラスティーズ オブ タフツ カレッジ 延伸したシルクｅｇｅｌ繊維およびその製造方法
JP5730317B2 (ja) 2009-09-29 2015-06-10 タフツ ユニバーシティー／トラスティーズ オブ タフツ カレッジ 絹ナノスフェアおよび絹マイクロスフェアならびにこれらを作製する方法
US9603971B2 (en) 2010-03-05 2017-03-28 Trustees Of Tufts College Silk-based ionomeric compositions
WO2012031144A2 (en) 2010-09-01 2012-03-08 Trustees Of Tufts College Silk fibroin and polyethylene glycol-based biomaterials
JP5937092B2 (ja) 2010-10-19 2016-06-22 トラスティーズ オブ タフツ カレッジ シルクフィブロインベースのマイクロニードルおよびその製造方法
KR101615474B1 (ko) 2010-12-16 2016-04-25 제넨테크, 인크. Th2 억제에 관한 진단 및 치료
US10335519B2 (en) 2011-04-20 2019-07-02 Trustees Of Tufts College Dynamic silk coatings for implantable devices
ES2856873T3 (es) 2012-02-06 2021-09-28 Childrens Medical Center Biomaterial multicapa para la regeneración de tejidos y la cicatrización de las heridas
ME03486B (me) 2012-10-12 2020-01-20 Medimmune Ltd Pirolobenzodiazepini i njihovi konjugati
CN105209077B (zh) 2013-03-13 2019-06-11 麦迪穆有限责任公司 吡咯并苯并二氮杂卓以及其结合物
US10188746B2 (en) 2014-09-10 2019-01-29 Medimmune Limited Pyrrolobenzodiazepines and conjugates thereof
JP2019534882A (ja) 2016-10-11 2019-12-05 メドイミューン・リミテッドＭｅｄＩｍｍｕｎｅ Ｌｉｍｉｔｅｄ 免疫介在性療法薬を有する抗体−薬物コンジュゲート
MX2020012418A (es) 2018-05-23 2021-04-28 Adc Therapeutics Sa Adyuvante molecular.
US20230372528A1 (en) 2020-10-16 2023-11-23 University Of Georgia Research Foundation, Inc. Glycoconjugates
GB202102396D0 (en) 2021-02-19 2021-04-07 Adc Therapeutics Sa Molecular adjuvant

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4361544A (en) * 1980-03-03 1982-11-30 Goldenberg Milton David Tumor localization and therapy with labeled antibodies specific to intracellular tumor-associated markers
JPH0811075B2 (ja) * 1982-06-30 1996-02-07 雄治 松岡 単クローン性抗ｃｅａ抗体
WO1984002983A1 (en) * 1983-01-21 1984-08-02 Frederick James Primus Specific cea-family antigens, antibodies specific thereto and their methods of use
DE3531301A1 (de) * 1985-09-02 1987-03-05 Behringwerke Ag Monoklonale antikoerper gegen tumorassoziierte glykoproteine, verfahren zu ihrer herstellung sowie ihre verwendung

Also Published As

Publication number Publication date
DE3887675T2 (de) 1994-06-30
EP0323805A2 (en) 1989-07-12
US5047507A (en) 1991-09-10
AU2739188A (en) 1989-07-06
PT89385B (pt) 1993-09-30
DK2289A (da) 1989-07-06
IE62439B1 (en) 1995-02-08
EP0323805A3 (en) 1990-04-25
DK172440B1 (da) 1998-07-27
ATE101202T1 (de) 1994-02-15
ES2061730T3 (es) 1994-12-16
CA1315219C (en) 1993-03-30
PT89385A (pt) 1990-02-08
EP0323805B1 (en) 1994-02-02
IE890018L (en) 1989-07-05
JPH025893A (ja) 1990-01-10
DE3887675D1 (de) 1994-03-17
AU619232B2 (en) 1992-01-23
GB8800078D0 (en) 1988-02-10

Similar Documents

Publication Publication Date Title
DK2289A (da) Monoklonale antistoffer samt deres fremstilling og anvendelse
EP0265500A4 (en) ANTIBODIES AGAINST HUMAN PROGESTERONE RECEPTOR AND DIAGNOSTIC PRODUCTS AND METHOD.
DK101890A (da) Monoklonale antistoffer mod human interleukin-4 og hybridomaer, der producerer saadanne
PT744958E (pt) Bancos de anticorpos policlonais
NO985150L (no) Antigenbindingsfragmenter som spesifikt detekterer cancerceller, nukleotider som koder fragmentene samt anvendelse derav for profylakse og deteksjon av cancere
ES2053810T3 (es) Nuevos anticuerpos quimericos.
ATE132197T1 (de) Monoklonale antikörper
FI950062A (fi) Proteiinien foroaktivaatio konjugaatiotarkoituksia varten
ATE244299T1 (de) Test und behandlung von demyelinierenden krankheiten wie multiple sklerosis
EP0352722A3 (en) Adenocarcinoma antigen binding methods and reagents
Vitetta et al. Characterization of the Spontaneous Murine B Cell Leukemia (BCL1) III. Evidence for Monoclonality by Using an anti-Idiotype Antibody
EP0232871A3 (en) Human monoclonal antibody, hybridoma producing the same and its use
WO1999002545A3 (en) Antigen binding fragments, designated 4b5, that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers
FI900230A0 (fi) Anti-idiotypa antikroppar mot antikroppar mot antigener med hoeg molekylvikt associerade till human melanoma.
DK314586A (da) Monoklonale antistoffer og antigener for humane lungecarcinomer, der ikke er af typen med smaa celler
DK172686A (da) Antigen opnaaet ud fra humant vaev, fremgangsmaade til under anvendelse af antigenet at fremstille monoklonale antistoffer til diagnose og behandling af cancer, fremgangsmaade til paavisning af cancer, samt antistoffer mod antigenet
NO177463C (no) STLV-III-beslektede polypeptider, diagnostiske prövesett og in vitro analysefremgangsmåte for påvisning av anti-HIV-2-antistoffer i kroppsvæskepröve
NO174110C (no) Monoklonalt antistoff til anvendelse in vitro for diagnose av maligne tumor- eller akutte inflammasjonssykdommer, og som er spesifikt for N-acetyl-neuraminsyre i hybridom som produserer antistoffet
ES2052913T3 (es) Ensayo inmunoquimico en cuanto al factor estimulante de colonias de granulocitos-macrofagos.
DE3582191D1 (de) Verwendung eines spezifischen karzinomassoziierenden antigens (hapten), fucosylsialosylgangliotetrose (fuc-gm1) in diagnostischen und therapeutischen verfahren betreffend den menschlichen lungenkrebs (carcinomas von kleinen zellen).
ZA884777B (en) Antigen recognized by mca 16 88
WO1986002651A3 (en) Specific carbohydrate-binding proteins (lectins) of mammalian tumor cells
IL67944A0 (en) Antibodies and antigens useful in the diagnosis and treatment of cancer,methods for the production thereof and methods for testing for the presence of cancer cells using the same
NO914094L (no) Nytt monoklonalt antistoff mot nytt antigen forbundet medhumantumorer
NO176903C (no) Antistoff eller bindende fragment derav til diagnostikk av humant carcinom, eller som transportör av farmasöytiske midler, isolert, humant tumor-assosiert antigen, diagnostisk middel og fremgangsmåte for in vitro-diagnostisering

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed