DK2289A - Monoklonale antistoffer samt deres fremstilling og anvendelse - Google Patents

Monoklonale antistoffer samt deres fremstilling og anvendelse

Info

Publication number
DK2289A
DK2289A DK002289A DK2289A DK2289A DK 2289 A DK2289 A DK 2289A DK 002289 A DK002289 A DK 002289A DK 2289 A DK2289 A DK 2289A DK 2289 A DK2289 A DK 2289A
Authority
DK
Denmark
Prior art keywords
antibodies
preparation
derivatives
monoclonal antibodies
therapy
Prior art date
Application number
DK002289A
Other languages
English (en)
Other versions
DK172440B1 (da
DK2289D0 (da
Inventor
Franz Buchegger
Jean-Pierre Mach
Original Assignee
Franz Buchegger
Res Corp Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Franz Buchegger, Res Corp Technologies Inc filed Critical Franz Buchegger
Publication of DK2289D0 publication Critical patent/DK2289D0/da
Publication of DK2289A publication Critical patent/DK2289A/da
Application granted granted Critical
Publication of DK172440B1 publication Critical patent/DK172440B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3007—Carcino-embryonic Antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK198900022A 1988-01-05 1989-01-04 Monoklonale antistoffer og derivater deraf, fremgangsmåde til deres fremstilling, hybridomacellelinie og fremgangsmåde til DK172440B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8800078 1988-01-05
GB888800078A GB8800078D0 (en) 1988-01-05 1988-01-05 Novel antibodies

Publications (3)

Publication Number Publication Date
DK2289D0 DK2289D0 (da) 1989-01-04
DK2289A true DK2289A (da) 1989-07-06
DK172440B1 DK172440B1 (da) 1998-07-27

Family

ID=10629465

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198900022A DK172440B1 (da) 1988-01-05 1989-01-04 Monoklonale antistoffer og derivater deraf, fremgangsmåde til deres fremstilling, hybridomacellelinie og fremgangsmåde til

Country Status (12)

Country Link
US (1) US5047507A (da)
EP (1) EP0323805B1 (da)
JP (1) JPH025893A (da)
AT (1) ATE101202T1 (da)
AU (1) AU619232B2 (da)
CA (1) CA1315219C (da)
DE (1) DE3887675T2 (da)
DK (1) DK172440B1 (da)
ES (1) ES2061730T3 (da)
GB (1) GB8800078D0 (da)
IE (1) IE62439B1 (da)
PT (1) PT89385B (da)

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EP0617127A1 (en) * 1987-12-31 1994-09-28 Tanox Biosystems, Inc. Antigenic epitopes on B cell-bound IgE Immunoglobulins
US5843708A (en) * 1988-01-05 1998-12-01 Ciba-Geigy Corporation Chimeric antibodies
GB8800077D0 (en) * 1988-01-05 1988-02-10 Ciba Geigy Ag Novel chimeric antibodies
EP0457875A4 (en) * 1989-11-13 1993-03-03 Xoma Corporation Chimeric mouse-human a10 antibody with specificity to a human tumor cell antigen
GB9014932D0 (en) * 1990-07-05 1990-08-22 Celltech Ltd Recombinant dna product and method
US5661016A (en) * 1990-08-29 1997-08-26 Genpharm International Inc. Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
WO1993015405A1 (en) * 1992-01-29 1993-08-05 Sci-Clone, Inc. Carcinoma associated antigen (sk1) monoclonal antibodies against sk1, methods of producing these antibodies and use therfor
ATE217909T1 (de) * 1992-02-14 2002-06-15 Suntory Ltd Verwendung und herstellung eines metastaseninhibitors bzw. eines zelladhäsionsinhibitors enthaltend einen antikörper
EP0584343B1 (en) * 1992-03-10 1999-01-20 La Jolla Cancer Research Foundation Recombinant calf intestinal alkaline phosphatase
US5502037A (en) * 1993-07-09 1996-03-26 Neuromed Technologies, Inc. Pro-cytotoxic drug conjugates for anticancer therapy
US5874540A (en) 1994-10-05 1999-02-23 Immunomedics, Inc. CDR-grafted type III anti-CEA humanized mouse monoclonal antibodies
ES2184812T3 (es) * 1994-11-28 2003-04-16 Abbott Lab Patrones para el dosificado inmunologico de esteroides estabilizados en solucion acuosa.
US5648268A (en) * 1994-12-06 1997-07-15 Ibm Corporation Radionuclide exchange detection of ultra trace ionic impurities in water
US6207805B1 (en) 1997-07-18 2001-03-27 University Of Iowa Research Foundation Prostate cell surface antigen-specific antibodies
US6682940B2 (en) * 1999-05-04 2004-01-27 Dan A. Pankowsky Products and methods for single parameter and multiparameter phenotyping of cells
US6828157B1 (en) * 1999-05-04 2004-12-07 Dan A. Pankowsky Products and methods for single parameter and multiparameter phenotyping of cells
US6774209B1 (en) 2000-04-03 2004-08-10 Dyax Corp. Binding peptides for carcinoembryonic antigen (CEA)
DE20105649U1 (de) * 2001-03-30 2001-08-16 Wang, Ming-Theng, Chungho, Taipeh Kettenzahnrad und Ratschenanordnung geringer Reibung für die rückwärtige Nabe eines Zweirades
CA2525994C (en) * 2002-06-24 2012-10-16 Tufts University Silk biomaterials and methods of use thereof
KR20050065587A (ko) 2002-10-08 2005-06-29 이뮤노메딕스, 인코오포레이티드 항체 치료법
WO2004062697A2 (en) 2003-01-07 2004-07-29 Tufts University Silk fibroin materials and use thereof
CA2562415C (en) 2003-04-10 2015-10-27 Tufts University Concentrated aqueous silk fibroin solutions free of organic solvents and uses thereof
WO2005000483A1 (en) * 2003-06-06 2005-01-06 Tufts University Method for forming inorganic coatings
JP2006214765A (ja) * 2005-02-01 2006-08-17 Bml Inc ヒトＡｐｏＡ−Ｖ蛋白質に対する抗体、及び、当該抗体を用いたヒトＡｐｏＡ−Ｖ蛋白質定量測定系
WO2008106485A2 (en) * 2007-02-27 2008-09-04 Trustees Of Tufts College Tissue-engineered silk organs
US8187616B2 (en) 2007-05-29 2012-05-29 Trustees Of Tufts College Method for silk fibroin gelation using sonication
CN101970023A (zh) * 2008-02-07 2011-02-09 塔夫茨大学信托人 三维的丝羟基磷灰石组合物
CA2721961A1 (en) * 2008-05-15 2009-11-19 Trustees Of Tufts College Silk polymer-based adenosine release: therapeutic potential for epilepsy
US8501172B2 (en) 2008-09-26 2013-08-06 Trustees Of Tufts College pH-induced silk gels and uses thereof
KR20110094277A (ko) 2008-10-09 2011-08-23 트러스티즈 오브 터프츠 칼리지 글리세롤을 함유하는 변성 실크 필름
CA2812635A1 (en) 2009-07-14 2011-01-20 Trustees Of Tufts College Electrospun silk material systems for wound healing
CA2775706A1 (en) 2009-09-28 2011-03-31 Trustees Of Tufts College Drawn silk egel fibers and methods of making same
JP5730317B2 (ja) 2009-09-29 2015-06-10 タフツ ユニバーシティー／トラスティーズ オブ タフツ カレッジ 絹ナノスフェアおよび絹マイクロスフェアならびにこれらを作製する方法
WO2011109691A2 (en) 2010-03-05 2011-09-09 Trustees Of Tufts College Silk-based ionomeric compositions
EP2611473A4 (en) 2010-09-01 2014-08-13 Tufts College SILK FIBROIN AND POLYETHYLENE GLYCOL BIOMATERIALS
JP5937092B2 (ja) 2010-10-19 2016-06-22 トラスティーズ オブ タフツ カレッジ シルクフィブロインベースのマイクロニードルおよびその製造方法
KR101615420B1 (ko) 2010-12-16 2016-04-26 제넨테크, 인크. Th2 억제에 관한 진단 및 치료
WO2012145652A1 (en) 2011-04-20 2012-10-26 Trustees Of Tufts College Dynamic silk coatings for implantable devices
EP2811987B1 (en) 2012-02-06 2021-01-20 Children's Medical Center Corporation Multi-layer biomaterial for tissue regeneration and wound healing
DK2839860T3 (da) 2012-10-12 2019-06-17 Medimmune Ltd Pyrrolobenzodiazepiner og konjugater deraf
ES2687439T3 (es) 2013-03-13 2018-10-25 Medimmune Limited Pirrolobenzodiazepinas y conjugados de las mismas
EP3193940A1 (en) 2014-09-10 2017-07-26 Medimmune Limited Pyrrolobenzodiazepines and conjugates thereof
CN109862919A (zh) 2016-10-11 2019-06-07 免疫医疗有限公司 抗体-药物缀合物联合免疫介导的治疗剂
CA3098103A1 (en) 2018-05-23 2019-11-28 Adc Therapeutics Sa Molecular adjuvant
US20230372528A1 (en) 2020-10-16 2023-11-23 University Of Georgia Research Foundation, Inc. Glycoconjugates
GB202102396D0 (en) 2021-02-19 2021-04-07 Adc Therapeutics Sa Molecular adjuvant
CN117980327A (zh) 2021-11-03 2024-05-03 杭州多禧生物科技有限公司 抗体的特异性偶联
US20260007869A1 (en) 2023-06-23 2026-01-08 Vaxess Technologies, Inc. Microneedle array patches (maps), systems, and methods for manufacturing and using same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4361544A (en) * 1980-03-03 1982-11-30 Goldenberg Milton David Tumor localization and therapy with labeled antibodies specific to intracellular tumor-associated markers
JPH0811075B2 (ja) * 1982-06-30 1996-02-07 雄治 松岡 単クローン性抗ｃｅａ抗体
AU582731B2 (en) * 1983-01-21 1989-04-13 Milton David Goldenberg Specific cea-family antigens, antibodies specific thereto and their methods of use
DE3531301A1 (de) * 1985-09-02 1987-03-05 Behringwerke Ag Monoklonale antikoerper gegen tumorassoziierte glykoproteine, verfahren zu ihrer herstellung sowie ihre verwendung

Also Published As

Publication number Publication date
DE3887675D1 (de) 1994-03-17
ES2061730T3 (es) 1994-12-16
EP0323805B1 (en) 1994-02-02
EP0323805A3 (en) 1990-04-25
ATE101202T1 (de) 1994-02-15
DK172440B1 (da) 1998-07-27
IE890018L (en) 1989-07-05
EP0323805A2 (en) 1989-07-12
AU619232B2 (en) 1992-01-23
CA1315219C (en) 1993-03-30
DE3887675T2 (de) 1994-06-30
JPH025893A (ja) 1990-01-10
IE62439B1 (en) 1995-02-08
DK2289D0 (da) 1989-01-04
US5047507A (en) 1991-09-10
AU2739188A (en) 1989-07-06
PT89385A (pt) 1990-02-08
GB8800078D0 (en) 1988-02-10
PT89385B (pt) 1993-09-30

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed