ES2184812T3 - Patrones para el dosificado inmunologico de esteroides estabilizados en solucion acuosa. - Google Patents
Patrones para el dosificado inmunologico de esteroides estabilizados en solucion acuosa.Info
- Publication number
- ES2184812T3 ES2184812T3 ES95939157T ES95939157T ES2184812T3 ES 2184812 T3 ES2184812 T3 ES 2184812T3 ES 95939157 T ES95939157 T ES 95939157T ES 95939157 T ES95939157 T ES 95939157T ES 2184812 T3 ES2184812 T3 ES 2184812T3
- Authority
- ES
- Spain
- Prior art keywords
- steroids
- stabilized
- patterns
- chelators
- water solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
- G01N33/743—Steroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/96—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood or serum control standard
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/963—Methods of stopping an enzyme reaction or stabilizing the test materials
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/967—Standards, controls, materials, e.g. validation studies, buffer systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
- Y10S436/817—Steroids or hormones
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/826—Additives, e.g. buffers, diluents, preservatives
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/104165—Lipid, cholesterol, or triglyceride standard or control
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Endocrinology (AREA)
- Steroid Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
LAS SOLUCIONES ACUOSAS DE COMPUESTOS ESTEROIDEOS CON ACTIVIDAD BIOLOGICA Y CON TENDENCIA A LA DEGRADACION OXIDATIVA A TEMPERATURAS ENTRE 2 Y 8 (GRADOS) C DURANTE LA CONSERVACION EN EXCESO DE VARIOS MESES SE ESTABILIZAN MEDIANTE ADICION DE QUELANTES. SOLUCIONES ACUOSAS CON UN INTERES PARTICULAR SON SOLUCIONES CON PROTEINAS QUE SIMULAN EL COMPORTAMIENTO DE FLUIDOS CORPORALES HUMANOS COMO SUERO Y QUE POR LO TANTO SON ADECUADOS COMO ESTANDARES PARA INMUNOENSAYOS DE ESTEROIDES EN DICHOS FLUIDOS CORPORALES. TIENEN UN INTERES PARTICULAR LOS QUELANTES METALES DE TRANSICION, ESPECIALMENTE AQUELLOS QUE SECUESTRAN HIERRO EFICIENTEMENTE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34518194A | 1994-11-28 | 1994-11-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2184812T3 true ES2184812T3 (es) | 2003-04-16 |
Family
ID=23353908
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES95939157T Expired - Lifetime ES2184812T3 (es) | 1994-11-28 | 1995-11-13 | Patrones para el dosificado inmunologico de esteroides estabilizados en solucion acuosa. |
Country Status (8)
Country | Link |
---|---|
US (1) | US6767708B1 (es) |
EP (1) | EP0795134B1 (es) |
JP (1) | JP3560979B2 (es) |
AT (1) | ATE223060T1 (es) |
CA (1) | CA2204027C (es) |
DE (1) | DE69527977T2 (es) |
ES (1) | ES2184812T3 (es) |
WO (1) | WO1996017252A1 (es) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6797479B2 (en) * | 1995-04-04 | 2004-09-28 | Abbott Laboratories | Reagents and methods for the detection and quantification of vancomycin in biological fluids |
US5699838A (en) | 1995-05-22 | 1997-12-23 | Inliner, U.S.A. | Apparatus for vacuum impregnation of a flexible, hollow tube |
US6475743B1 (en) * | 1998-10-02 | 2002-11-05 | Ischemia Technologies, Inc. | Marker useful for detection and measurement of free radical damage and method |
US20030215359A1 (en) * | 1998-10-02 | 2003-11-20 | Ischemia Technologies, Inc. | Tests for the rapid evaluation of ischemic states and kits |
US20050142613A1 (en) * | 1998-10-02 | 2005-06-30 | David Bar-Or | Test for the rapid evaluation of ischemic states and kits |
US7297544B2 (en) * | 1998-10-02 | 2007-11-20 | Ischemia Technologies, Inc. | Tests for the rapid evaluation of ischemic states and kits |
US7070937B1 (en) | 1998-10-02 | 2006-07-04 | Ischemia Technologies, Inc. | Marker useful for detection and measurement of free radical damage and method |
US7449338B2 (en) * | 1998-10-02 | 2008-11-11 | Ischemia Technologies, Inc. | Tests for the rapid evaluation of ischemic states and kits |
JP2005506515A (ja) * | 2000-12-13 | 2005-03-03 | バイオ−ラッド ラボラトリーズ,インコーポレイティド | 多種検定用の標準希釈液 |
US20040261816A1 (en) * | 2003-06-27 | 2004-12-30 | Brask Justin K. | Using bidentate chelators to clean semiconductor wafers |
US20070141710A1 (en) * | 2005-12-20 | 2007-06-21 | Beckman Coulter, Inc. | Stable calibrators for immunoassays |
DK2116241T3 (en) | 2007-01-26 | 2016-06-06 | Pola Pharma Inc | pharmaceutical composition |
CN110579615A (zh) * | 2019-09-06 | 2019-12-17 | 广州科方生物技术股份有限公司 | 一种通用于血清中类固醇激素的释放剂及其制备方法 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3274062A (en) * | 1963-08-20 | 1966-09-20 | Hyland Lab | Diagnostic reagent |
US4786606A (en) * | 1981-01-23 | 1988-11-22 | Baxter Travenol Laboratories, Inc. | Solid phase system for ligand assay |
DE3122917A1 (de) * | 1981-06-10 | 1983-02-24 | Boehringer Mannheim Gmbh, 6800 Mannheim | Waessrige cholesterin-standardloesung und verfahren zu ihrer herstellung |
US4432964A (en) * | 1981-08-24 | 1984-02-21 | Alza Corporation | Topical composition containing steroid in two forms released independently from polymeric carrier |
US4344940A (en) * | 1981-11-30 | 1982-08-17 | E. R. Squibb & Sons, Inc. | Steroid formulation containing dipotassium EDTA |
US4436738A (en) * | 1982-03-15 | 1984-03-13 | Mead Johnson & Company | Stabilized estradiol cream composition |
US4672028A (en) * | 1984-05-23 | 1987-06-09 | Icn Micromedic Systems, Inc. | Compositions and method for simultaneous multiple array of analytes using radioisotope chelate labels |
DE3445010A1 (de) * | 1984-12-10 | 1986-06-19 | Boehringer Mannheim Gmbh | Kontroll- bzw. eichserum fuer die lipid-diagnostik |
US4707453A (en) * | 1985-04-05 | 1987-11-17 | Becton Dickinson And Company | Vesicle including a metal marker for use in an assay |
GB8800078D0 (en) * | 1988-01-05 | 1988-02-10 | Ciba Geigy Ag | Novel antibodies |
US5342760A (en) * | 1992-06-10 | 1994-08-30 | Abbott Laboratories | Determination of estradiol by competitive immunoassay |
US5296377A (en) * | 1992-12-15 | 1994-03-22 | Boehringer Mannheim Corporation | Control reagent containing a hydroxylamine or an antioxidant |
-
1995
- 1995-11-13 EP EP95939157A patent/EP0795134B1/en not_active Expired - Lifetime
- 1995-11-13 ES ES95939157T patent/ES2184812T3/es not_active Expired - Lifetime
- 1995-11-13 DE DE69527977T patent/DE69527977T2/de not_active Expired - Lifetime
- 1995-11-13 WO PCT/US1995/014845 patent/WO1996017252A1/en active IP Right Grant
- 1995-11-13 JP JP51883496A patent/JP3560979B2/ja not_active Expired - Fee Related
- 1995-11-13 AT AT95939157T patent/ATE223060T1/de not_active IP Right Cessation
- 1995-11-13 CA CA002204027A patent/CA2204027C/en not_active Expired - Fee Related
- 1995-12-08 US US08/569,886 patent/US6767708B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE69527977D1 (de) | 2002-10-02 |
EP0795134A1 (en) | 1997-09-17 |
DE69527977T2 (de) | 2003-05-08 |
EP0795134B1 (en) | 2002-08-28 |
WO1996017252A1 (en) | 1996-06-06 |
JPH10512362A (ja) | 1998-11-24 |
ATE223060T1 (de) | 2002-09-15 |
CA2204027A1 (en) | 1996-06-06 |
CA2204027C (en) | 2006-03-14 |
US6767708B1 (en) | 2004-07-27 |
JP3560979B2 (ja) | 2004-09-02 |
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