ATE101202T1 - Antikoerper. - Google Patents
Antikoerper.Info
- Publication number
- ATE101202T1 ATE101202T1 AT88810897T AT88810897T ATE101202T1 AT E101202 T1 ATE101202 T1 AT E101202T1 AT 88810897 T AT88810897 T AT 88810897T AT 88810897 T AT88810897 T AT 88810897T AT E101202 T1 ATE101202 T1 AT E101202T1
- Authority
- AT
- Austria
- Prior art keywords
- antibodies
- derivatives
- therapy
- cea
- processes
- Prior art date
Links
- 102000012406 Carcinoembryonic Antigen Human genes 0.000 abstract 2
- 108010022366 Carcinoembryonic Antigen Proteins 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 201000011510 cancer Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 238000002560 therapeutic procedure Methods 0.000 abstract 2
- 230000002494 anti-cea effect Effects 0.000 abstract 1
- 238000003149 assay kit Methods 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 210000004408 hybridoma Anatomy 0.000 abstract 1
- 238000012544 monitoring process Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000000306 recurrent effect Effects 0.000 abstract 1
- 230000003248 secreting effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3007—Carcino-embryonic Antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB888800078A GB8800078D0 (en) | 1988-01-05 | 1988-01-05 | Novel antibodies |
| EP88810897A EP0323805B1 (de) | 1988-01-05 | 1988-12-28 | Antikörper |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE101202T1 true ATE101202T1 (de) | 1994-02-15 |
Family
ID=10629465
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88810897T ATE101202T1 (de) | 1988-01-05 | 1988-12-28 | Antikoerper. |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5047507A (de) |
| EP (1) | EP0323805B1 (de) |
| JP (1) | JPH025893A (de) |
| AT (1) | ATE101202T1 (de) |
| AU (1) | AU619232B2 (de) |
| CA (1) | CA1315219C (de) |
| DE (1) | DE3887675T2 (de) |
| DK (1) | DK172440B1 (de) |
| ES (1) | ES2061730T3 (de) |
| GB (1) | GB8800078D0 (de) |
| IE (1) | IE62439B1 (de) |
| PT (1) | PT89385B (de) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE122006000007I2 (de) * | 1987-12-31 | 2008-03-27 | Tanox Inc | -tragenden b-lymphocyten befinden. |
| US5843708A (en) * | 1988-01-05 | 1998-12-01 | Ciba-Geigy Corporation | Chimeric antibodies |
| GB8800077D0 (en) * | 1988-01-05 | 1988-02-10 | Ciba Geigy Ag | Novel chimeric antibodies |
| AU634314B2 (en) * | 1989-11-13 | 1993-02-18 | Green Cross Corporation, The | Chimeric mouse-human a10 antibody with specificity to a human tumor cell antigen |
| GB9014932D0 (en) * | 1990-07-05 | 1990-08-22 | Celltech Ltd | Recombinant dna product and method |
| US5661016A (en) * | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| EP0672253A4 (de) * | 1992-01-29 | 1995-12-06 | Sci Clone Inc | Monoklonale antikorper gegen das karzinom assoziierte antigen ski, verfahrenzu ihrer herstellung und ihre verwendung. |
| DE69331942T2 (de) * | 1992-02-14 | 2002-10-02 | Suntory Limited, Osaka | Verwendung und herstellung eines metastaseninhibitors bzw. eines zelladhäsionsinhibitors enthaltend einen antikörper |
| DE69323131T2 (de) * | 1992-03-10 | 1999-09-16 | La Jolla Cancer Research Foundation, La Jolla | Rekombinierte alkalische phosphatase aus kälberdarm |
| US5502037A (en) * | 1993-07-09 | 1996-03-26 | Neuromed Technologies, Inc. | Pro-cytotoxic drug conjugates for anticancer therapy |
| US5874540A (en) * | 1994-10-05 | 1999-02-23 | Immunomedics, Inc. | CDR-grafted type III anti-CEA humanized mouse monoclonal antibodies |
| EP0795134B1 (de) * | 1994-11-28 | 2002-08-28 | Abbott Laboratories | Stabile wässrige Steroid-Standardproben für Immuntests |
| US5648268A (en) * | 1994-12-06 | 1997-07-15 | Ibm Corporation | Radionuclide exchange detection of ultra trace ionic impurities in water |
| US6207805B1 (en) | 1997-07-18 | 2001-03-27 | University Of Iowa Research Foundation | Prostate cell surface antigen-specific antibodies |
| US6682940B2 (en) | 1999-05-04 | 2004-01-27 | Dan A. Pankowsky | Products and methods for single parameter and multiparameter phenotyping of cells |
| US6828157B1 (en) | 1999-05-04 | 2004-12-07 | Dan A. Pankowsky | Products and methods for single parameter and multiparameter phenotyping of cells |
| US6774209B1 (en) * | 2000-04-03 | 2004-08-10 | Dyax Corp. | Binding peptides for carcinoembryonic antigen (CEA) |
| US20020139628A1 (en) * | 2001-03-30 | 2002-10-03 | Wen-Chen Chang | Retractable handle assembly |
| EP2447055B1 (de) * | 2002-06-24 | 2017-12-06 | Tufts University | Seidenbiomaterialien und Verfahren zu ihrer Verwendung |
| JP4790413B2 (ja) | 2002-10-08 | 2011-10-12 | イミューノメディクス、インコーポレイテッド | 抗体療法 |
| WO2004062697A2 (en) | 2003-01-07 | 2004-07-29 | Tufts University | Silk fibroin materials and use thereof |
| WO2005012606A2 (en) * | 2003-04-10 | 2005-02-10 | Tufts University | Concentrated aqueous silk fibroin solution and use thereof |
| WO2005000483A1 (en) * | 2003-06-06 | 2005-01-06 | Tufts University | Method for forming inorganic coatings |
| JP2006214765A (ja) * | 2005-02-01 | 2006-08-17 | Bml Inc | ヒトApoA−V蛋白質に対する抗体、及び、当該抗体を用いたヒトApoA−V蛋白質定量測定系 |
| US9102916B2 (en) | 2007-02-27 | 2015-08-11 | Trustees Of Tufts College | Tissue-engineered silk organs |
| DK2211876T3 (en) | 2007-05-29 | 2015-01-12 | Tufts College | PROCESS FOR silk fibroin-GELATION USING sonication |
| CN101970023A (zh) * | 2008-02-07 | 2011-02-09 | 塔夫茨大学信托人 | 三维的丝羟基磷灰石组合物 |
| US9040073B2 (en) * | 2008-05-15 | 2015-05-26 | Trustees Of Tufts College | Silk polymer-based adenosine release: therapeutic potential for epilepsy |
| US8501172B2 (en) | 2008-09-26 | 2013-08-06 | Trustees Of Tufts College | pH-induced silk gels and uses thereof |
| EP2349367A4 (de) | 2008-10-09 | 2013-09-04 | Tufts College | Modifizierte seidenfilme mit glycerol |
| US8728498B2 (en) | 2009-07-14 | 2014-05-20 | Trustees Of Tufts College | Electrospun silk material systems for wound healing |
| CA2775706A1 (en) | 2009-09-28 | 2011-03-31 | Trustees Of Tufts College | Drawn silk egel fibers and methods of making same |
| IN2012DN02358A (de) | 2009-09-29 | 2015-08-21 | Tufts College | |
| US9603971B2 (en) | 2010-03-05 | 2017-03-28 | Trustees Of Tufts College | Silk-based ionomeric compositions |
| US9566365B2 (en) | 2010-09-01 | 2017-02-14 | Trustees Of Tufts College | Silk fibroin and polyethylene glycol-based biomaterials |
| EP4218891A1 (de) | 2010-10-19 | 2023-08-02 | Trustees Of Tufts College | Mikronadeln auf seidenfibroinbasis und verfahren zur herstellung davon |
| JP6005657B2 (ja) | 2010-12-16 | 2016-10-12 | ジェネンテック, インコーポレイテッド | Th2阻害に関連する診断及び治療 |
| WO2012145652A1 (en) | 2011-04-20 | 2012-10-26 | Trustees Of Tufts College | Dynamic silk coatings for implantable devices |
| WO2013119551A1 (en) | 2012-02-06 | 2013-08-15 | Children's Medical Center Corporation | Multi-layer biomaterial for tissue regeneration and wound healing |
| CA2941485C (en) | 2012-10-12 | 2018-06-12 | Philip Wilson Howard | Pyrrolobenzodiazepines and conjugates thereof |
| AU2014230735B2 (en) | 2013-03-13 | 2018-03-15 | Medimmune Limited | Pyrrolobenzodiazepines and conjugates thereof |
| JP6531166B2 (ja) | 2014-09-10 | 2019-06-12 | メドイミューン・リミテッドMedImmune Limited | ピロロベンゾジアゼピン及びそのコンジュゲート |
| JP2019534882A (ja) | 2016-10-11 | 2019-12-05 | メドイミューン・リミテッドMedImmune Limited | 免疫介在性療法薬を有する抗体−薬物コンジュゲート |
| EP3796942A1 (de) | 2018-05-23 | 2021-03-31 | ADC Therapeutics SA | Molekulares adjuvans |
| WO2022079211A1 (en) | 2020-10-16 | 2022-04-21 | Adc Therapeutics Sa | Glycoconjugates |
| GB202102396D0 (en) | 2021-02-19 | 2021-04-07 | Adc Therapeutics Sa | Molecular adjuvant |
| CN117980327A (zh) | 2021-11-03 | 2024-05-03 | 杭州多禧生物科技有限公司 | 抗体的特异性偶联 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4361544A (en) * | 1980-03-03 | 1982-11-30 | Goldenberg Milton David | Tumor localization and therapy with labeled antibodies specific to intracellular tumor-associated markers |
| JPH0811075B2 (ja) * | 1982-06-30 | 1996-02-07 | 雄治 松岡 | 単クローン性抗cea抗体 |
| CA1274794A (en) * | 1983-01-21 | 1990-10-02 | Frederick James Primus | Specific cea-family antigens, antibodies specific thereto and their methods of use |
| DE3531301A1 (de) * | 1985-09-02 | 1987-03-05 | Behringwerke Ag | Monoklonale antikoerper gegen tumorassoziierte glykoproteine, verfahren zu ihrer herstellung sowie ihre verwendung |
-
1988
- 1988-01-05 GB GB888800078A patent/GB8800078D0/en active Pending
- 1988-12-22 AU AU27391/88A patent/AU619232B2/en not_active Ceased
- 1988-12-28 AT AT88810897T patent/ATE101202T1/de not_active IP Right Cessation
- 1988-12-28 EP EP88810897A patent/EP0323805B1/de not_active Expired - Lifetime
- 1988-12-28 DE DE3887675T patent/DE3887675T2/de not_active Expired - Fee Related
- 1988-12-28 ES ES88810897T patent/ES2061730T3/es not_active Expired - Lifetime
-
1989
- 1989-01-03 CA CA000587378A patent/CA1315219C/en not_active Expired - Fee Related
- 1989-01-03 PT PT89385A patent/PT89385B/pt not_active IP Right Cessation
- 1989-01-04 IE IE1889A patent/IE62439B1/en not_active IP Right Cessation
- 1989-01-04 US US07/293,467 patent/US5047507A/en not_active Expired - Fee Related
- 1989-01-04 DK DK198900022A patent/DK172440B1/da not_active IP Right Cessation
- 1989-01-05 JP JP64000176A patent/JPH025893A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| GB8800078D0 (en) | 1988-02-10 |
| AU619232B2 (en) | 1992-01-23 |
| PT89385B (pt) | 1993-09-30 |
| IE62439B1 (en) | 1995-02-08 |
| DK2289A (da) | 1989-07-06 |
| JPH025893A (ja) | 1990-01-10 |
| CA1315219C (en) | 1993-03-30 |
| US5047507A (en) | 1991-09-10 |
| DK2289D0 (da) | 1989-01-04 |
| IE890018L (en) | 1989-07-05 |
| EP0323805A2 (de) | 1989-07-12 |
| ES2061730T3 (es) | 1994-12-16 |
| AU2739188A (en) | 1989-07-06 |
| EP0323805A3 (en) | 1990-04-25 |
| DK172440B1 (da) | 1998-07-27 |
| DE3887675D1 (de) | 1994-03-17 |
| DE3887675T2 (de) | 1994-06-30 |
| EP0323805B1 (de) | 1994-02-02 |
| PT89385A (pt) | 1990-02-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE101202T1 (de) | Antikoerper. | |
| EP0265500A4 (de) | Antikörper gegen menschlichen progesteronrezeptor sowie diagnosematerial und -verfahren. | |
| NZ217829A (en) | Monoclonal anti-human breast cancer antibodies and test reagent | |
| DK40885A (da) | Monoklonalt antistof, fremgangsmaade og celle til fremstilling deraf,fremgangsmaade til fremstilling af cellen og farmaceutisk praeparat indeholdende det monoklonale antistof | |
| PT744958E (pt) | Bancos de anticorpos policlonais | |
| DK101890A (da) | Monoklonale antistoffer mod human interleukin-4 og hybridomaer, der producerer saadanne | |
| DE68925226D1 (de) | Monoklonale Antikörper | |
| FI950062A0 (fi) | Proteiinien foroaktivaatio konjugaatiotarkoituksia varten | |
| EP0352722A3 (de) | Bindungstests für Adenocarcinoma-Antigen und Reagenzien | |
| Vitetta et al. | Characterization of the Spontaneous Murine B Cell Leukemia (BCL1) III. Evidence for Monoclonality by Using an anti-Idiotype Antibody | |
| DE69333076D1 (de) | Test und behandlung von demyelinierenden krankheiten wie multiple sklerosis | |
| FI900230A0 (fi) | Anti-idiotypa antikroppar mot antikroppar mot antigener med hoeg molekylvikt associerade till human melanoma. | |
| Reinsberg et al. | Evidence for interaction of human anti-idiotypic antibodies with CA 125 determination in a patient after radioimmunodetection | |
| JPH04507285A (ja) | 抗イディオトープ免疫検定法 | |
| Boylston | Theta antigen and immunoglobulin on a tissue-cultured mouse lymphoma | |
| Gold et al. | Murine monoclonal antibodies to colon-specific antigen p | |
| Moroz et al. | A hereditary immunoglobulin A abnormality: absence of light-heavy—chain assembly: Study of immunoglobulin synthesis in tonsillar cells | |
| AU2070688A (en) | Antigen recognized by mca 16-88 | |
| WO1986002651A3 (en) | Specific carbohydrate-binding proteins (lectins) of mammalian tumor cells | |
| Ho et al. | Evaluation of factors affecting the performance of enzymatic SPan-1 immunoassays for pancreatic cancer | |
| NO924803L (no) | Tumor-relatert monoklonalt antistoff 88bv59 | |
| JPS61160060A (ja) | ヒト偏平上皮肺癌腫細胞に特異的なモノクロ−ナル抗体およびその製造ならびに使用 | |
| FR2311844A1 (fr) | Preparation d'anticorps, antigene et procede pour le diagnostic de l'embolie pulmonaire | |
| GR890100333A (en) | Antihuman antigen antibodies | |
| IL67944A0 (en) | Antibodies and antigens useful in the diagnosis and treatment of cancer,methods for the production thereof and methods for testing for the presence of cancer cells using the same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |