DE68925226D1 - Monoklonale Antikörper - Google Patents

Monoklonale Antikörper

Info

Publication number
DE68925226D1
DE68925226D1 DE68925226T DE68925226T DE68925226D1 DE 68925226 D1 DE68925226 D1 DE 68925226D1 DE 68925226 T DE68925226 T DE 68925226T DE 68925226 T DE68925226 T DE 68925226T DE 68925226 D1 DE68925226 D1 DE 68925226D1
Authority
DE
Germany
Prior art keywords
antibodies
fragments
monoclonal antibodies
cell surface
human cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68925226T
Other languages
English (en)
Other versions
DE68925226T2 (de
Inventor
Manfred Dr Brockhaus
Hansruedi Dr Loetscher
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of DE68925226D1 publication Critical patent/DE68925226D1/de
Publication of DE68925226T2 publication Critical patent/DE68925226T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE68925226T 1988-03-17 1989-03-14 Monoklonale Antikörper Expired - Fee Related DE68925226T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888806339A GB8806339D0 (en) 1988-03-17 1988-03-17 Monoclonal antibodies

Publications (2)

Publication Number Publication Date
DE68925226D1 true DE68925226D1 (de) 1996-02-08
DE68925226T2 DE68925226T2 (de) 1996-05-15

Family

ID=10633598

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68925226T Expired - Fee Related DE68925226T2 (de) 1988-03-17 1989-03-14 Monoklonale Antikörper

Country Status (10)

Country Link
EP (1) EP0334165B1 (de)
JP (1) JPH02154695A (de)
AT (1) ATE132197T1 (de)
AU (1) AU618326B2 (de)
DE (1) DE68925226T2 (de)
DK (1) DK113389A (de)
GB (1) GB8806339D0 (de)
IE (1) IE890853L (de)
NZ (1) NZ228296A (de)
ZA (1) ZA891861B (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL83878A (en) * 1987-09-13 1995-07-31 Yeda Res & Dev Soluble protein corresponding to tnf inhibitory protein its preparation and pharmaceutical compositions containing it
US5359037A (en) * 1988-09-12 1994-10-25 Yeda Research And Development Co. Ltd. Antibodies to TNF binding protein I
IL94039A (en) * 1989-08-06 2006-09-05 Yeda Res & Dev Antibodies to tbp - 1 and their use
US7264944B1 (en) 1989-04-21 2007-09-04 Amgen Inc. TNF receptors, TNF binding proteins and DNAs coding for them
DE59010941D1 (de) 1989-04-21 2005-03-24 Amgen Inc TNF-Rezeptor, TNF bindende Proteine und dafür kodierende DNAs
US6221675B1 (en) 1989-04-21 2001-04-24 Amgen, Inc. TNF receptors, TNF binding proteins and DNAs coding for them
DE69017753T3 (de) * 1989-05-18 2013-06-20 Yeda Research And Development Co., Ltd. Tumor-Nekrosefaktor-Bindungsprotein II, seine Reinigung und spezifische Antikörper
US6232446B1 (en) * 1989-05-18 2001-05-15 Yeda Research And Development Co. Ltd. TNF ligands
US6143866A (en) * 1989-07-18 2000-11-07 Amgen, Inc. Tumor necrosis factor (TNF) inhibitor and method for obtaining the same
IL95031A (en) 1989-07-18 2007-03-08 Amgen Inc A method of producing a recombinant human necrotic factor absorber
DK0491878T3 (da) * 1989-08-16 1997-06-23 Chiron Corp Præparater til inhibering af proteinhormondannelse og anvendelser deraf
NZ235148A (en) 1989-09-05 1991-12-23 Immunex Corp Tumour necrosis factor receptor protein and dna sequences
CA2485553A1 (en) * 1989-09-05 1991-03-21 Immunex Corporation Tumor necrosis factor - .alpha. and - .beta. receptors
US5395760A (en) * 1989-09-05 1995-03-07 Immunex Corporation DNA encoding tumor necrosis factor-α and -β receptors
EP0417563B1 (de) 1989-09-12 2000-07-05 F. Hoffmann-La Roche Ag TNF-bindende Proteine
DE4006269A1 (de) * 1990-02-28 1991-08-29 Max Planck Gesellschaft Antikoerper gegen den tumor-nekrosefaktor-rezeptor
US6552170B1 (en) 1990-04-06 2003-04-22 Amgen Inc. PEGylation reagents and compounds formed therewith
ATE198770T1 (de) * 1991-06-19 2001-02-15 Boehringer Ingelheim Int Monoklonale antikörper gegen das humane tnf- bindende protein i (tnf-bp i)
US5582998A (en) * 1991-06-19 1996-12-10 Boehringer Ingelheim International Gmbh Monoclonal antibodies against human TNF-binding protein I (TNF-BP I) and immunoassays therefor
EP0585705B1 (de) * 1992-08-28 1998-11-04 Bayer Corporation Verwendung von monoklonalen Anti-TNF-Antikörpern für die Behandlung von bakteriellen Meningitiden
IT1270943B (it) * 1993-05-14 1997-05-26 Mini Ricerca Scient Tecnolog Anticorpi monoclonali anti-recettore di tipo i tnf alfa, procedimento per la produzione e loro usi
EP0791360A3 (de) * 1996-02-29 1997-09-24 Bayer Corporation Behandlung von septischem Schock mit Anti-TNF Antikörper
TW555765B (en) 1996-07-09 2003-10-01 Amgen Inc Low molecular weight soluble tumor necrosis factor type-I and type-II proteins
CA2273850A1 (en) 1996-12-06 1998-06-11 Amgen Inc. Combination therapy using a tnf binding protein for treating tnf-mediated diseases
US9028822B2 (en) 2002-06-28 2015-05-12 Domantis Limited Antagonists against TNFR1 and methods of use therefor
WO2017083525A1 (en) 2015-11-11 2017-05-18 Opi Vi- Ip Holdco Llc Composition and methods for anti-tnfr2 antibodies

Also Published As

Publication number Publication date
ATE132197T1 (de) 1996-01-15
NZ228296A (en) 1992-01-29
AU3125289A (en) 1989-09-21
DK113389D0 (da) 1989-03-08
IE890853L (en) 1989-09-17
DE68925226T2 (de) 1996-05-15
GB8806339D0 (en) 1988-04-13
EP0334165B1 (de) 1995-12-27
EP0334165A2 (de) 1989-09-27
AU618326B2 (en) 1991-12-19
EP0334165A3 (en) 1990-05-16
ZA891861B (en) 1989-11-29
JPH02154695A (ja) 1990-06-14
DK113389A (da) 1989-09-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee