DK2281605T3 - Apparat til behandling af en tumor med et elektrisk felt - Google Patents

Apparat til behandling af en tumor med et elektrisk felt Download PDF

Info

Publication number
DK2281605T3
DK2281605T3 DK10012777.8T DK10012777T DK2281605T3 DK 2281605 T3 DK2281605 T3 DK 2281605T3 DK 10012777 T DK10012777 T DK 10012777T DK 2281605 T3 DK2281605 T3 DK 2281605T3
Authority
DK
Denmark
Prior art keywords
tumor
treating
electric field
electric
field
Prior art date
Application number
DK10012777.8T
Other languages
English (en)
Inventor
Yoram Palti
Original Assignee
Novocure Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/263,329 external-priority patent/US7136699B2/en
Priority claimed from US10/285,313 external-priority patent/US7089054B2/en
Application filed by Novocure Gmbh filed Critical Novocure Gmbh
Application granted granted Critical
Publication of DK2281605T3 publication Critical patent/DK2281605T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/40Applying electric fields by inductive or capacitive coupling ; Applying radio-frequency signals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00017Electrical control of surgical instruments
    • A61B2017/00022Sensing or detecting at the treatment site
    • A61B2017/00084Temperature

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Radiology & Medical Imaging (AREA)
  • Surgery (AREA)
  • Otolaryngology (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Plasma & Fusion (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Electrotherapy Devices (AREA)
  • Professional, Industrial, Or Sporting Protective Garments (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK10012777.8T 2002-10-02 2003-10-01 Apparat til behandling af en tumor med et elektrisk felt DK2281605T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10/263,329 US7136699B2 (en) 2002-10-02 2002-10-02 Apparatus for destroying dividing cells
US10/285,313 US7089054B2 (en) 2002-10-02 2002-10-31 Apparatus and method for treating a tumor or the like
US10/315,576 US6868289B2 (en) 2002-10-02 2002-12-10 Apparatus for treating a tumor or the like and articles incorporating the apparatus for treatment of the tumor
EP03799042.1A EP1545704B1 (en) 2002-10-02 2003-10-01 Apparatus for treating a tumor by an electric field

Publications (1)

Publication Number Publication Date
DK2281605T3 true DK2281605T3 (da) 2020-08-24

Family

ID=32074281

Family Applications (7)

Application Number Title Priority Date Filing Date
DK10012702.6T DK2281602T3 (da) 2002-10-02 2003-10-01 Apparat til behandling af en tumor med et elektrisk felt
DK10012706.7T DK2281603T3 (da) 2002-10-02 2003-10-01 Apparat til behandling af en tumor med et elektrisk felt
DK10012777.8T DK2281605T3 (da) 2002-10-02 2003-10-01 Apparat til behandling af en tumor med et elektrisk felt
DK19183539.6T DK3572123T3 (da) 2002-10-02 2003-10-01 Apparat til behandling af en tumor med et elektrisk felt
DK10012716.6T DK2281604T3 (da) 2002-10-02 2003-10-01 Apparat til behandling af en tumor med et elektrisk felt
DK03799042.1T DK1545704T3 (da) 2002-10-02 2003-10-01 Apparat til behandling af en tumor med et elektrisk felt
DK19219623.6T DK3656441T3 (da) 2002-10-02 2003-10-01 Apparat til behandling af en tumor med et elektrisk felt

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DK10012702.6T DK2281602T3 (da) 2002-10-02 2003-10-01 Apparat til behandling af en tumor med et elektrisk felt
DK10012706.7T DK2281603T3 (da) 2002-10-02 2003-10-01 Apparat til behandling af en tumor med et elektrisk felt

Family Applications After (4)

Application Number Title Priority Date Filing Date
DK19183539.6T DK3572123T3 (da) 2002-10-02 2003-10-01 Apparat til behandling af en tumor med et elektrisk felt
DK10012716.6T DK2281604T3 (da) 2002-10-02 2003-10-01 Apparat til behandling af en tumor med et elektrisk felt
DK03799042.1T DK1545704T3 (da) 2002-10-02 2003-10-01 Apparat til behandling af en tumor med et elektrisk felt
DK19219623.6T DK3656441T3 (da) 2002-10-02 2003-10-01 Apparat til behandling af en tumor med et elektrisk felt

Country Status (11)

Country Link
US (2) US6868289B2 (da)
EP (8) EP2281605B1 (da)
JP (1) JP4350042B2 (da)
CN (1) CN1703258A (da)
AU (1) AU2003265066A1 (da)
CA (3) CA3100056A1 (da)
DK (7) DK2281602T3 (da)
ES (7) ES2881730T3 (da)
HU (6) HUE051961T2 (da)
PT (7) PT2281605T (da)
WO (1) WO2004030760A2 (da)

Families Citing this family (166)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8175698B2 (en) * 2000-02-17 2012-05-08 Novocure Ltd. Treating bacteria with electric fields
JP5280600B2 (ja) 2000-02-17 2013-09-04 パルティ、ヨーラム 分裂中の細胞を破壊するための方法および装置
US7089054B2 (en) * 2002-10-02 2006-08-08 Standen Ltd. Apparatus and method for treating a tumor or the like
US7136699B2 (en) * 2002-10-02 2006-11-14 Standen, Ltd. Apparatus for destroying dividing cells
US8447395B2 (en) * 2000-02-17 2013-05-21 Novocure Ltd Treating bacteria with electric fields
US7914470B2 (en) * 2001-01-12 2011-03-29 Celleration, Inc. Ultrasonic method and device for wound treatment
US8235919B2 (en) * 2001-01-12 2012-08-07 Celleration, Inc. Ultrasonic method and device for wound treatment
US7653438B2 (en) 2002-04-08 2010-01-26 Ardian, Inc. Methods and apparatus for renal neuromodulation
US7853333B2 (en) 2002-04-08 2010-12-14 Ardian, Inc. Methods and apparatus for multi-vessel renal neuromodulation
US8131371B2 (en) 2002-04-08 2012-03-06 Ardian, Inc. Methods and apparatus for monopolar renal neuromodulation
US8145316B2 (en) 2002-04-08 2012-03-27 Ardian, Inc. Methods and apparatus for renal neuromodulation
US9308043B2 (en) 2002-04-08 2016-04-12 Medtronic Ardian Luxembourg S.A.R.L. Methods for monopolar renal neuromodulation
US8150519B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods and apparatus for bilateral renal neuromodulation
US7617005B2 (en) 2002-04-08 2009-11-10 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US7162303B2 (en) 2002-04-08 2007-01-09 Ardian, Inc. Renal nerve stimulation method and apparatus for treatment of patients
US20080213331A1 (en) 2002-04-08 2008-09-04 Ardian, Inc. Methods and devices for renal nerve blocking
US9308044B2 (en) 2002-04-08 2016-04-12 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US20070129761A1 (en) 2002-04-08 2007-06-07 Ardian, Inc. Methods for treating heart arrhythmia
US8150520B2 (en) 2002-04-08 2012-04-03 Ardian, Inc. Methods for catheter-based renal denervation
US6978174B2 (en) 2002-04-08 2005-12-20 Ardian, Inc. Methods and devices for renal nerve blocking
US9636174B2 (en) 2002-04-08 2017-05-02 Medtronic Ardian Luxembourg S.A.R.L. Methods for therapeutic renal neuromodulation
US7620451B2 (en) 2005-12-29 2009-11-17 Ardian, Inc. Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach
US7756583B2 (en) 2002-04-08 2010-07-13 Ardian, Inc. Methods and apparatus for intravascularly-induced neuromodulation
US20140018880A1 (en) 2002-04-08 2014-01-16 Medtronic Ardian Luxembourg S.A.R.L. Methods for monopolar renal neuromodulation
US20070135875A1 (en) 2002-04-08 2007-06-14 Ardian, Inc. Methods and apparatus for thermally-induced renal neuromodulation
US8145317B2 (en) 2002-04-08 2012-03-27 Ardian, Inc. Methods for renal neuromodulation
US8347891B2 (en) 2002-04-08 2013-01-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for performing a non-continuous circumferential treatment of a body lumen
US8774913B2 (en) 2002-04-08 2014-07-08 Medtronic Ardian Luxembourg S.A.R.L. Methods and apparatus for intravasculary-induced neuromodulation
US8774922B2 (en) 2002-04-08 2014-07-08 Medtronic Ardian Luxembourg S.A.R.L. Catheter apparatuses having expandable balloons for renal neuromodulation and associated systems and methods
US20040059385A1 (en) * 2002-09-25 2004-03-25 Yu Tsung I. Low frequency assistor for electric-stimulating breast acupuncture point portions of a human body
DE10260149A1 (de) * 2002-12-20 2004-07-01 BSH Bosch und Siemens Hausgeräte GmbH Vorrichtung zur Bestimmung des Leitwertes von Wäsche, Wäschetrockner und Verfahren zur Verhinderung von Schichtbildung auf Elektroden
JP4750784B2 (ja) * 2004-04-23 2011-08-17 ノヴォキュアー・リミテッド 異なる周波数の電界による腫瘍等の治療
US7937143B2 (en) 2004-11-02 2011-05-03 Ardian, Inc. Methods and apparatus for inducing controlled renal neuromodulation
EP2345451B1 (en) * 2004-12-07 2018-01-24 Novocure Limited Electrodes for applying an electric field in-vivo over an extended period of time
EP1833554A2 (en) * 2004-12-27 2007-09-19 Standen Ltd. Treating a tumor or the like with electric fields at different orientations
JP4602145B2 (ja) * 2005-04-04 2010-12-22 伊藤超短波株式会社 高周波加熱治療装置
US20060282122A1 (en) * 2005-06-08 2006-12-14 Yoram Palti Treating cancer with electric fields that are guided to desired locations within a body
US20070021803A1 (en) * 2005-07-22 2007-01-25 The Foundry Inc. Systems and methods for neuromodulation for treatment of pain and other disorders associated with nerve conduction
PT3804809T (pt) 2005-10-03 2024-03-07 Novocure Gmbh Otimização das características de um campo elétrico para aumentar o efeito do campo nas células em proliferação
US8226811B2 (en) 2005-11-02 2012-07-24 May-Ruben Technologies, Inc. High impedance system for generating electric fields and method of use
CN101331392B (zh) * 2005-11-02 2012-08-08 梅-鲁宾科技公司 用于产生电场的高阻抗系统及所使用的方法
US8019414B2 (en) * 2006-04-05 2011-09-13 Novocure Ltd. Treating cancer using electromagnetic fields in combination with other treatment regimens
WO2008034103A2 (en) 2006-09-14 2008-03-20 Lazure Technologies, Llc Device and method for destruction of cancer cells
JP4183264B2 (ja) * 2006-12-07 2008-11-19 ココロカ株式会社 電位治療用局所導子
JP4179626B2 (ja) * 2006-12-07 2008-11-12 ココロカ株式会社 電位治療用局所導子
US8491521B2 (en) * 2007-01-04 2013-07-23 Celleration, Inc. Removable multi-channel applicator nozzle
DK2167194T3 (da) 2007-03-06 2017-06-19 Novocure Ltd Behandling af cancer under anvendelse af elektromagnetiske felter i kombination med fotodynamisk terapi
WO2009022225A1 (en) * 2007-08-14 2009-02-19 Novocure Ltd. Treating parasites with electric fields
US8562602B2 (en) 2007-09-14 2013-10-22 Lazure Technologies, Llc Multi-layer electrode ablation probe and related methods
CA2699782C (en) * 2007-09-14 2017-04-11 Lazure Technologies, Llc Prostate cancer ablation
US20090076500A1 (en) * 2007-09-14 2009-03-19 Lazure Technologies, Llc Multi-tine probe and treatment by activation of opposing tines
US20090177123A1 (en) * 2007-12-28 2009-07-09 Celleration, Inc. Methods for treating inflammatory disorders
EP2082777A1 (en) 2008-01-27 2009-07-29 Oncotherm Kft. Flexible and porous large-area electrode for heating
US7866527B2 (en) 2008-02-14 2011-01-11 Ethicon Endo-Surgery, Inc. Surgical stapling apparatus with interlockable firing system
US8172835B2 (en) 2008-06-05 2012-05-08 Cutera, Inc. Subcutaneous electric field distribution system and methods
US20100022919A1 (en) * 2008-07-22 2010-01-28 Celleration, Inc. Methods of Skin Grafting Using Ultrasound
US20100022999A1 (en) * 2008-07-24 2010-01-28 Gollnick David A Symmetrical rf electrosurgical system and methods
US20100100093A1 (en) * 2008-09-16 2010-04-22 Lazure Technologies, Llc. System and method for controlled tissue heating for destruction of cancerous cells
US8808281B2 (en) * 2008-10-21 2014-08-19 Microcube, Llc Microwave treatment devices and methods
US11291503B2 (en) * 2008-10-21 2022-04-05 Microcube, Llc Microwave treatment devices and methods
US9980774B2 (en) * 2008-10-21 2018-05-29 Microcube, Llc Methods and devices for delivering microwave energy
US11219484B2 (en) 2008-10-21 2022-01-11 Microcube, Llc Methods and devices for delivering microwave energy
JP6083928B2 (ja) * 2008-10-21 2017-02-22 マイクロキューブ, エルエルシー 身体組織にエネルギーに印加する方法および装置
CN102256560B (zh) * 2008-11-10 2014-07-09 微立方有限责任公司 将能量应用于身体组织的方法和装置
US8652129B2 (en) 2008-12-31 2014-02-18 Medtronic Ardian Luxembourg S.A.R.L. Apparatus, systems, and methods for achieving intravascular, thermally-induced renal neuromodulation
US8728139B2 (en) 2009-04-16 2014-05-20 Lazure Technologies, Llc System and method for energy delivery to a tissue using an electrode array
US9037227B2 (en) * 2009-09-01 2015-05-19 Roman A. Slizynski Use of impedance techniques in breast-mass detection
US9526911B1 (en) 2010-04-27 2016-12-27 Lazure Scientific, Inc. Immune mediated cancer cell destruction, systems and methods
EP2632373B1 (en) 2010-10-25 2018-07-18 Medtronic Ardian Luxembourg S.à.r.l. System for evaluation and feedback of neuromodulation treatment
US8684901B1 (en) 2010-11-22 2014-04-01 Jacob Zabara Electromagnetic radiation treatment for cancer and pathological genetic regulations
US9233257B1 (en) 2010-11-22 2016-01-12 Jacob Zabara Electromagnetic radiation treatment
WO2013105987A2 (en) 2011-02-15 2013-07-18 Hemosonics, Llc Characterization of blood hemostasis and oxygen transport parameters
CN102178523B (zh) * 2011-04-18 2012-08-29 吴广延 实验用颅内埋置绝缘电极
WO2013134733A2 (en) 2012-03-08 2013-09-12 Medtronic Ardian Luxembourg Sarl Biomarker sampling in the context of neuromodulation devices and associated systems and methods
US9750568B2 (en) 2012-03-08 2017-09-05 Medtronic Ardian Luxembourg S.A.R.L. Ovarian neuromodulation and associated systems and methods
US20140110296A1 (en) 2012-10-19 2014-04-24 Medtronic Ardian Luxembourg S.A.R.L. Packaging for Catheter Treatment Devices and Associated Devices, Systems, and Methods
CN103908744A (zh) * 2013-01-06 2014-07-09 张涛 一种低强度电流电场癌症治疗设备及方法
US10428637B2 (en) 2013-03-04 2019-10-01 Fereidoun Abbassian System and console for monitoring and managing well site operations
WO2014151600A2 (en) 2013-03-15 2014-09-25 Fereidoun Abbassian System and console for monitoring and managing cementing operations at a well site
WO2014151619A2 (en) 2013-03-15 2014-09-25 Fereidoun Abbassian System and console for monitoring and managing casing running operations at a well site
WO2014151643A2 (en) 2013-03-15 2014-09-25 Fereidoun Abbassian System and console for monitoring and managing well site operations
WO2014151627A2 (en) 2013-03-15 2014-09-25 Fereidoun Abbassian System and console for rig site fluid management at a well site
US10779875B2 (en) 2013-05-06 2020-09-22 Novocure Gmbh Optimizing treatment using TTfields by changing the frequency during the course of long term tumor treatment
US9655669B2 (en) 2013-05-06 2017-05-23 Novocure Limited Optimizing treatment using TTFields by changing the frequency during the course of long term tumor treatment
US11047221B2 (en) 2013-06-30 2021-06-29 Fereidoun Abbassian System and console for monitoring and managing well site operations
US11224767B2 (en) 2013-11-26 2022-01-18 Sanuwave Health, Inc. Systems and methods for producing and delivering ultrasonic therapies for wound treatment and healing
CN103638603B (zh) * 2013-12-25 2016-05-25 王卫东 一种穿戴式电场治疗装置
US9962161B2 (en) 2014-02-12 2018-05-08 Ethicon Llc Deliverable surgical instrument
US10194980B1 (en) 2014-03-28 2019-02-05 Medtronic Ardian Luxembourg S.A.R.L. Methods for catheter-based renal neuromodulation
US10194979B1 (en) 2014-03-28 2019-02-05 Medtronic Ardian Luxembourg S.A.R.L. Methods for catheter-based renal neuromodulation
US9980766B1 (en) 2014-03-28 2018-05-29 Medtronic Ardian Luxembourg S.A.R.L. Methods and systems for renal neuromodulation
US10301923B2 (en) 2014-05-02 2019-05-28 Kongsberg Oil And Gas Technologies As System and console for monitoring and managing well site drilling operations
US10260332B2 (en) 2014-05-02 2019-04-16 Kongsberg Oil And Gas Technologies As System and console for monitoring and managing well site operations
US10323502B2 (en) 2014-05-02 2019-06-18 Kongsberg Oil And Gas Technologies As System and console for monitoring and managing tripping operations at a well site
US9833617B2 (en) 2014-07-25 2017-12-05 Loyalty Based Innovations, LLC Apparatus and method for treating multiple tumors in patients with metastatic disease by electric fields
US20190117963A1 (en) 2014-07-25 2019-04-25 Loyalty Based Innovations, LLC Apparatus and method for treating multiple tumors in patients with metastatic disease by electric fields
CN104383635A (zh) * 2014-11-28 2015-03-04 际华三五二二装具饰品有限公司 一种乳腺肿块治疗仪
US9726647B2 (en) 2015-03-17 2017-08-08 Hemosonics, Llc Determining mechanical properties via ultrasound-induced resonance
CN104857632B (zh) * 2015-05-11 2018-01-12 武汉弘跃医药科技有限公司 一种脑损伤治疗仪
KR101688520B1 (ko) * 2015-05-14 2016-12-22 고려대학교 산학협력단 불연속적인 분할 교류 전기장을 이용한 암 치료 장치 및 방법
KR102186403B1 (ko) * 2015-09-04 2020-12-04 고려대학교 산학협력단 교류 전기장과 방사선 치료의 융합을 이용한 암 치료 장치
US10188851B2 (en) * 2015-10-28 2019-01-29 Novocure Limited TTField treatment with optimization of electrode positions on the head based on MRI-based conductivity measurements
US10821283B2 (en) 2016-04-04 2020-11-03 Novocure Gmbh Reducing motility of cancer cells using tumor treating fields (TTFields)
JP6980706B2 (ja) 2016-06-30 2021-12-15 ノボキュア ゲーエムベーハー 身体への腫瘍治療電場の長手方向伝達用のアレイ
ES2661110B1 (es) * 2016-09-26 2018-07-09 Indiba, S.A. Dispositivo de diatermia
JP6573920B2 (ja) * 2017-01-10 2019-09-11 深江 公俊 低周波電気刺激用絶縁体電極及び装置
EP3571503A1 (en) 2017-01-19 2019-11-27 Moshe Giladi System for viewing cell cultures under a microscope whilst applying ttfields
JP2018126431A (ja) * 2017-02-10 2018-08-16 協栄ハイパーサーミア株式会社 高周波温熱治療装置
CN106823145A (zh) * 2017-03-24 2017-06-13 长沙普特斯科技有限公司 一种采用调幅电场治疗肿瘤的装置
US11338135B2 (en) 2017-10-23 2022-05-24 Cardiac Pacemakers, Inc. Medical devices for cancer therapy with electric field shaping elements
US20190117970A1 (en) * 2017-10-23 2019-04-25 Cardiac Pacemakers, Inc. Electric field shaping leads for treatment of cancer
US20190117969A1 (en) * 2017-10-23 2019-04-25 Cardiac Pacemakers, Inc. Medical devices for treatment of cancer with electric fields
US11213349B2 (en) 2017-11-07 2022-01-04 Evanesc Therapeutics, Inc. Apparatus for treating tumors by evanescent waves
US20220125510A1 (en) * 2020-10-26 2022-04-28 Evanesc Therapeutics, Inc. Apparatus for application of evanescent waves to biological tissues
US10953209B2 (en) 2018-03-28 2021-03-23 Board Of Regents Of The University Of Texas System Treating tumors using TTFields combined with a PARP inhibitor
US11058886B1 (en) 2018-04-05 2021-07-13 Evanesc Therapeutics, Inc. Method of polarization control of evanescent waves for treating tumors
CN112566665A (zh) 2018-04-09 2021-03-26 莫舍·吉拉迪 用TTFields和Aurora激酶抑制剂治疗肿瘤
CN112424626A (zh) 2018-04-10 2021-02-26 吉夫·波姆桑 从具有不同重复时间的两个mri图像导出的低频(<1mhz)ac电导率估计
EP3815739A4 (en) * 2018-05-21 2021-06-16 Fukae Technologies LLC WATERPROOF HOUSING FOR LOW FREQUENCY ELECTROSTIMULATION DEVICE, WATERPROOF LOW FREQUENCY ELECTROSTIMULATION DEVICE AND INSULATOR ELECTRODE FOR LOW FREQUENCY ELECTROSTIMULATION
CN116173401A (zh) 2018-07-03 2023-05-30 埃德温·阊 使用交变电场提高细胞膜通透性
US11179322B2 (en) 2018-07-10 2021-11-23 Novocure Gmbh Methods and compositions for treating tumors with TTFields and sorafenib
KR20210030971A (ko) 2018-07-10 2021-03-18 노보큐어 게엠베하 교류 전기장을 사용한 바이러스 감염 억제
KR102607603B1 (ko) 2018-07-18 2023-11-29 노보큐어 게엠베하 종양 치료장의 용량을 정량화하기 위한 전력 손실 밀도 및 관련 측정값의 사용
ES2911526T3 (es) 2018-08-23 2022-05-19 Novocure Gmbh Utilización de campos eléctricos alternos para aumentar la permeabilidad de la barrera de sangre cerebral
WO2020047285A1 (en) * 2018-08-29 2020-03-05 Regents Of The University Of Minnesota Devices and methods for treatment of tumors using electromagnetic signal
US11160977B2 (en) 2018-09-04 2021-11-02 Novocure Gmbh Delivering tumor treating fields (TTFields) to the infratentorial brain
WO2020049482A1 (en) 2018-09-07 2020-03-12 Yaniv Alon Treating autoimmune diseases using an alternating electric field to reduce the proliferation of t-cells
US11986647B2 (en) 2018-09-07 2024-05-21 Novocure Gmbh Treating autoinflammatory and mitochondrial diseases using an alternating electric field
WO2020079554A1 (en) 2018-10-15 2020-04-23 Zeev Bomzon Generating tumor treating fields (ttfields) with high uniformity throughout the brain
JP7148722B2 (ja) 2018-10-25 2022-10-05 ゼーヴ・ボンゾン 被験者の脊椎構造体に対する交番電界(例えばTTField)の送達
EP4019080A1 (en) 2018-11-19 2022-06-29 Novocure GmbH Arrays for delivering tumor treating fields (ttfields) with selectively addressable sub-elements
BR112021004336A2 (pt) 2018-11-29 2021-08-17 Novocure Gmbh matrizes de transdutor com flexibilidade melhorada para entregar ttfields (campos de tratamento de tumor)
EP3968279A1 (en) 2019-01-08 2022-03-16 Novocure GmbH Evaluating quality of segmentation of an image into different types of tissue for planning treatment using tumor treating fields (ttfields)
JP2022519782A (ja) 2019-02-07 2022-03-24 ヴィヴェーク・ケー・シャルマ 交番極性磁場によってがん細胞を治療するシステム、および方法
US11027143B2 (en) 2020-02-06 2021-06-08 Vivek K. Sharma System and methods for treating cancer cells with alternating polarity magnetic fields
US11344740B2 (en) 2019-02-07 2022-05-31 Asha Medical, Inc. System and methods for treating cancer cells with alternating polarity magnetic fields
WO2020174403A1 (en) 2019-02-26 2020-09-03 Moshe Giladi Determining a frequency for ttfields treatment based on an electrical characteristic of targeted cancer cells
JP2022522936A (ja) 2019-02-27 2022-04-21 ノボキュア ゲーエムベーハー 埋込可能な変換器アレイを使用した腫瘍治療電場(ttfields)の送達
JP7419391B2 (ja) 2019-03-29 2024-01-22 ノボキュア ゲーエムベーハー PTGER3阻害剤によりTTFields-耐性がん細胞におけるTTFieldsに対する感受性を回復させるための方法
ES2940749T3 (es) 2019-04-17 2023-05-11 Novocure Gmbh Carga de datos desde un sistema aislado sin comprometer el aislamiento
JP7382422B2 (ja) * 2019-04-22 2023-11-16 ボストン サイエンティフィック サイムド,インコーポレイテッド 癌の併用電気化学療法
CN113766949A (zh) 2019-04-22 2021-12-07 波士顿科学国际有限公司 用于施用电刺激以治疗癌症的系统
WO2020219336A1 (en) 2019-04-22 2020-10-29 Boston Scientific Scimed, Inc. Electrical stimulation devices for cancer treatment
JP7476231B2 (ja) 2019-04-23 2024-04-30 ボストン サイエンティフィック サイムド,インコーポレイテッド 温熱療法又は熱モニタと共に行われる電気刺激
EP4356955A2 (en) 2019-04-23 2024-04-24 Boston Scientific Scimed, Inc. Electrodes for electrical stimulation to treat cancer
WO2020219517A2 (en) 2019-04-23 2020-10-29 Boston Scientific Scimed, Inc. Electrical stimulation for cancer treatment with internal and external electrodes
KR20210003333A (ko) * 2019-07-01 2021-01-12 고려대학교 산학협력단 피부에 인가되는 분산 전류를 이용한 전기장 기반 암 치료장치
JP7472264B2 (ja) 2019-07-31 2024-04-22 ノボキュア ゲーエムベーハー 頭蓋骨インプラントに埋め込まれた電極による腫瘍治療電場(ttフィールド)の印加
JP2022545794A (ja) * 2019-08-30 2022-10-31 ノボキュア ゲーエムベーハー 頸部への腫瘍治療電界(TTFields)の印加
MX2022006136A (es) 2019-12-31 2022-06-17 Novocure Gmbh Matrices para suministrar campos de tratamiento de tumores (ttfields) con elementos de electrodos y sensores de temperatura accesibles individualmente.
WO2021137085A2 (en) 2019-12-31 2021-07-08 Novocure Gmbh High voltage, high efficiency sine wave generator that prevents spikes during amplitude adjustments and switching of channels
CN115515674A (zh) 2020-02-24 2022-12-23 波士顿科学国际有限公司 用于治疗胰腺癌的系统和方法
JP2021171078A (ja) * 2020-04-20 2021-11-01 相元 金 電気治療用端子、電気治療用装置及び電気治療方法
CA3171313A1 (en) 2020-04-24 2021-10-28 Novocure Gmbh Using alternating electric fields to increase permeability of the blood brain barrier
WO2021223684A1 (zh) * 2020-05-02 2021-11-11 电冷科学有限公司 一种避免活性非消融电极附近组织损伤的装置
WO2021257967A1 (en) 2020-06-19 2021-12-23 The Methodist Hospital Dba Houston Methodist Hospital Method and apparatus for oncomagnetic treatment
US11818943B2 (en) 2020-06-25 2023-11-14 Novocure Gmbh Fabricating organic light emitting diodes (OLEDs) using tubulin
WO2022035719A1 (en) 2020-08-07 2022-02-17 Sharma Vivek K System and methods for treating cancer cells with alternating polarity magnetic fields
TWI830958B (zh) * 2020-10-16 2024-02-01 瑞士商諾沃庫勒有限責任公司 用於判定傳感器陣列在個體之身體上之最佳位置以及規劃電極元件集合在個體之身體上之定位的方法
TWI815047B (zh) * 2020-10-16 2023-09-11 瑞士商諾沃庫勒有限責任公司 藉由使用TTFields活化STING途徑以降低癌細胞生存力的方法
CN112694974B (zh) * 2020-11-26 2023-02-10 中国石油大学(华东) 针对纳秒脉冲电场消融动态监测系统构建及监测方法
CN112933407A (zh) * 2021-01-28 2021-06-11 杭州维那泰克医疗科技有限责任公司 电极结构、电极贴片及细胞分裂抑制装置
EP4329872A1 (en) 2021-04-27 2024-03-06 Cardoaid Ltd Multisite leadless cardiac resynchronization
KR102568337B1 (ko) * 2021-09-30 2023-08-21 주식회사 필드큐어 전극 시스템의 최적화 방법
TR2021016189A2 (tr) * 2021-10-18 2021-11-22 Revotera Medikal Teknolojiler Anonim Sirketi Kapasi̇tans tabanli dc şarj-deşarj kanser tedavi̇ ci̇hazi ve yöntemi̇
CN115970155B (zh) * 2023-03-22 2023-08-22 深圳奥派森生物电磁科技有限公司 金属基板电极、肿瘤电场治疗电极及系统

Family Cites Families (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR446660A (fr) 1911-09-02 1912-12-12 Gottlieb Schuettel Dispositif pour métiers continus à anneaux pour monter les curseurs sur les anneaux
DE559353C (de) * 1929-07-25 1932-09-19 Lorenz Akt Ges C Einrichtung zur Diathermiebehandlung mittels Hochfrequenz im Kondensatorfeld
US2065295A (en) * 1935-05-16 1936-12-22 Arthur G Sullivan Therapeutic appliance
FR833516A (fr) * 1939-01-10 1938-10-24 Electrode pneumatique souple et dilatable pour traitements par ondes courtes et courants diathermiques
US3741219A (en) * 1971-11-24 1973-06-26 R Sessions Grounding place or electrode for electromedical equipment
BE794566A (fr) 1972-01-28 1973-07-26 Esb Inc Regenerateur et stimulateur bioelectrochimique et procedes d'application in vivo d'energie electrique a des cellules et des tissus.
DE2314573C2 (de) * 1973-03-23 1986-12-18 Werner Dipl.-Ing. 8000 München Kraus Gerät zur Förderung von Heilungsprozessen
US3991770A (en) 1974-01-24 1976-11-16 Leveen Harry H Method for treating benign and malignant tumors utilizing radio frequency, electromagnetic radiation
US4016886A (en) 1974-11-26 1977-04-12 The United States Of America As Represented By The United States Energy Research And Development Administration Method for localizing heating in tumor tissue
US4121592A (en) 1975-08-04 1978-10-24 Critical Systems, Inc. Apparatus for heating tissue
IE43147B1 (en) * 1975-08-04 1980-12-31 Critical Systems Apparatus for treating tumors
US4154246A (en) * 1977-07-25 1979-05-15 Leveen Harry H Field intensification in radio frequency thermotherapy
DE2907013A1 (de) 1978-02-24 1979-08-30 American Med Syst Verfahren und vorrichtung zum beguenstigen der heilung von verletzten knochenknorpeln und geweben im gesichtsbereich
DE2813068A1 (de) 1978-03-25 1979-10-04 Philips Patentverwaltung Verfahren und vorrichtung zur ermittlung von inneren koerperstrukturen
GB2043453A (en) 1979-02-22 1980-10-08 Electrochem Tech Corp Improvements in or relating to an electrode
US4472506A (en) 1981-01-13 1984-09-18 Liburdy Robert P Method for determining cell membrane dielectric breakdown
US4467809A (en) 1982-09-17 1984-08-28 Biolectron, Inc. Method for non-invasive electrical stimulation of epiphyseal plate growth
US4622952A (en) 1983-01-13 1986-11-18 Gordon Robert T Cancer treatment method
CA1244889A (en) 1983-01-24 1988-11-15 Kureha Chemical Ind Co Ltd HYPERTHERMIA DEVICE
US4729377A (en) * 1983-06-01 1988-03-08 Bio-Stimu Trend Corporation Garment apparatus for delivering or receiving electric impulses
DE3323415C2 (de) 1983-06-29 1985-04-25 Kernforschungsanlage Jülich GmbH, 5170 Jülich Verwendung eines Verfahrens und einer Vorrichtung zur Bestimmung von Zellinhaltstoffe sezernierenden Zellen
JPS6096266A (ja) * 1983-10-31 1985-05-29 陶山 純夫 高周波加温治療装置
SE455920B (sv) 1986-01-29 1988-08-22 Hans Wiksell Anordning for hypertermibehandling av tumorer
US4923814A (en) 1986-05-09 1990-05-08 Electropore, Inc. High speed, high power apparatus for vesicle prealignment, poration, loading and fusion in uniform electric fields and method therefor
CN86103803B (zh) 1986-06-05 1987-11-18 北京信息工程学院 静电场治疗装置
US4822470A (en) 1987-10-09 1989-04-18 Baylor College Of Medicine Method of and apparatus for cell poration and cell fusion using radiofrequency electrical pulses
US4936303A (en) 1987-11-20 1990-06-26 Ultrathermics Ultrasonic heating apparatus and method
JPH0629196B2 (ja) 1987-12-01 1994-04-20 甲子郎 梅村 超音波による腫瘍治療用生理作用増強剤
WO1989006555A1 (en) * 1988-01-21 1989-07-27 Massachusetts Institute Of Technology Transport of molecules across tissue using electroporation
US5389069A (en) 1988-01-21 1995-02-14 Massachusetts Institute Of Technology Method and apparatus for in vivo electroporation of remote cells and tissue
FR2627987B3 (fr) 1988-03-04 1990-02-02 Indiba Sa Appareil electronique pour la therapie medicale et cosmetique
US5158071A (en) 1988-07-01 1992-10-27 Hitachi, Ltd. Ultrasonic apparatus for therapeutical use
GB8904998D0 (en) * 1989-03-04 1989-04-19 Matthews Tony Anaesthetising apparatus
US5099756A (en) 1989-06-01 1992-03-31 Harry H. Leveen Radio frequency thermotherapy
US5441746A (en) 1989-12-22 1995-08-15 Molecular Bioquest, Inc. Electromagnetic wave absorbing, surface modified magnetic particles for use in medical applications, and their method of production
IL93579A0 (en) * 1990-02-28 1990-11-29 Srd Medical Ltd Apparatus for rapidly preparing to obtain biosignals
JPH04126163A (ja) * 1990-06-13 1992-04-27 Omron Corp 温熱治療装置
US5236410A (en) 1990-08-02 1993-08-17 Ferrotherm International, Inc. Tumor treatment method
WO1992019286A1 (en) 1991-05-03 1992-11-12 University Technologies International, Inc. Biofilm reduction method
US5441532A (en) 1991-06-26 1995-08-15 Massachusetts Institute Of Technology Adaptive focusing and nulling hyperthermia annular and monopole phased array applicators
CN1018716B (zh) * 1991-06-29 1992-10-21 金来贵 中频脉冲整体治疗仪
US6024733A (en) * 1995-06-07 2000-02-15 Arthrocare Corporation System and method for epidermal tissue ablation
US5468223A (en) 1992-11-30 1995-11-21 C.N.R.S. Paris Electrochemotherapy
US5386837A (en) 1993-02-01 1995-02-07 Mmtc, Inc. Method for enhancing delivery of chemotherapy employing high-frequency force fields
FR2703253B1 (fr) 1993-03-30 1995-06-23 Centre Nat Rech Scient Applicateur d'impulsions electriques pour traitement de tissus biologiques.
GB9318853D0 (en) * 1993-09-11 1993-10-27 Walton John H D Improvements in relation to medical diathermy
IL108775A (en) 1994-02-25 2003-09-17 Univ Ramot Method for efficient incorporation of molecules into cells
US5718248A (en) * 1994-04-15 1998-02-17 Allegheny-Singer Research Institute Muscle energy converter pump and method of pumping fluid of a patient
US5704355A (en) 1994-07-01 1998-01-06 Bridges; Jack E. Non-invasive system for breast cancer detection
WO1997004830A1 (en) 1995-07-28 1997-02-13 Gray James R Use of a polarizing field to modify the efficacy of a bioactive agent
IT1277888B1 (it) * 1995-07-31 1997-11-12 Cafiero Franconi Schermi elettromagnetici per termoterapia.
US5606971A (en) 1995-11-13 1997-03-04 Artann Corporation, A Nj Corp. Method and device for shear wave elasticity imaging
US5718246A (en) 1996-01-03 1998-02-17 Preferential, Inc. Preferential induction of electrically mediated cell death from applied pulses
SE9600389D0 (sv) * 1996-02-02 1996-02-02 Pacesetter Ab Medical device used to stimulate tissue
US5911223A (en) * 1996-08-09 1999-06-15 Massachusetts Institute Of Technology Introduction of modifying agents into skin by electroporation
US5984882A (en) 1996-08-19 1999-11-16 Angiosonics Inc. Methods for prevention and treatment of cancer and other proliferative diseases with ultrasonic energy
US5869326A (en) 1996-09-09 1999-02-09 Genetronics, Inc. Electroporation employing user-configured pulsing scheme
US6246913B1 (en) * 1997-02-14 2001-06-12 Oractec Interventions, Inc. Method and apparatus for the treatment of strabismus
US6055453A (en) 1997-08-01 2000-04-25 Genetronics, Inc. Apparatus for addressing needle array electrodes for electroporation therapy
WO1999011771A1 (en) * 1997-09-04 1999-03-11 Science Research Laboratory, Inc. Cell separation using electric fields
US6027488A (en) 1998-06-03 2000-02-22 Genetronics, Inc. Flow-through electroporation system for ex vivo gene therapy
US5976092A (en) 1998-06-15 1999-11-02 Chinn; Douglas O. Combination stereotactic surgical guide and ultrasonic probe
US6319901B1 (en) 1998-10-15 2001-11-20 Ichor Medical Systems, Inc. Methods for prolonging cell membrane permeability
SE9804450D0 (sv) * 1998-12-17 1998-12-17 Robotkonsult Ab Metod och anordningar för automatisk in-line kalibrering av robot, verktyg och cell
ES2240078T3 (es) 1999-03-09 2005-10-16 Thermage, Inc. Aparato para el tratamiento de tejidos.
US6678558B1 (en) 1999-03-25 2004-01-13 Genetronics, Inc. Method and apparatus for reducing electroporation-mediated muscle reaction and pain response
US6738663B2 (en) * 1999-04-09 2004-05-18 Oncostim, A Minnesota Corporation Implantable device and method for the electrical treatment of cancer
US6366808B1 (en) 2000-03-13 2002-04-02 Edward A. Schroeppel Implantable device and method for the electrical treatment of cancer
AU5530900A (en) * 1999-07-01 2001-01-22 N.V. Bekaert S.A. Garment comprising electrode
US6433553B1 (en) * 1999-10-27 2002-08-13 Varian Semiconductor Equipment Associates, Inc. Method and apparatus for eliminating displacement current from current measurements in a plasma processing system
JP2001183367A (ja) * 1999-12-27 2001-07-06 Fuji Photo Film Co Ltd 固相担体表面へのdna断片の固定方法及びdnaチップ
US6853864B2 (en) 2000-02-02 2005-02-08 Catholic University Of America, The Use of electromagnetic fields in cancer and other therapies
JP5280600B2 (ja) 2000-02-17 2013-09-04 パルティ、ヨーラム 分裂中の細胞を破壊するための方法および装置
US7146210B2 (en) 2000-02-17 2006-12-05 Standen Ltd. Apparatus and method for optimizing tumor treatment efficiency by electric fields
US7016725B2 (en) 2001-11-06 2006-03-21 Standen Ltd. Method and apparatus for destroying dividing cells
US6546290B1 (en) 2000-04-12 2003-04-08 Roamitron Holding S.A. Method and apparatus for electromedical therapy
WO2001091637A1 (en) * 2000-05-29 2001-12-06 Medicotest A/S An electrode for establishing electrical contact with the skin
AU2002244900A1 (en) * 2001-03-21 2002-10-03 Bmr Research And Development Limited A garment for attaching electrodes to a subject
US6994706B2 (en) 2001-08-13 2006-02-07 Minnesota Medical Physics, Llc Apparatus and method for treatment of benign prostatic hyperplasia
US6783647B2 (en) * 2001-10-19 2004-08-31 Ut-Battelle, Llc Microfluidic systems and methods of transport and lysis of cells and analysis of cell lysate
JP4750784B2 (ja) * 2004-04-23 2011-08-17 ノヴォキュアー・リミテッド 異なる周波数の電界による腫瘍等の治療

Also Published As

Publication number Publication date
EP3659671A1 (en) 2020-06-03
EP2281604A1 (en) 2011-02-09
JP2006513739A (ja) 2006-04-27
ES2811751T3 (es) 2021-03-15
WO2004030760A3 (en) 2004-07-22
HUE050874T2 (hu) 2021-01-28
JP4350042B2 (ja) 2009-10-21
EP2281605A2 (en) 2011-02-09
US7706890B2 (en) 2010-04-27
AU2003265066A8 (en) 2004-04-23
CA2930736A1 (en) 2004-04-15
EP1545704B1 (en) 2020-08-12
PT3656441T (pt) 2021-08-11
PT3572123T (pt) 2020-09-08
ES2688188T3 (es) 2018-10-31
EP2281603B1 (en) 2020-06-10
EP2281604B1 (en) 2020-06-10
PT2281604T (pt) 2020-09-08
HUE050725T2 (hu) 2021-01-28
EP3656441A1 (en) 2020-05-27
HUE050650T2 (hu) 2020-12-28
EP3572123B1 (en) 2020-06-10
EP2281603A3 (en) 2011-06-22
ES2813058T3 (es) 2021-03-22
CA2499845A1 (en) 2004-04-15
EP2281602B1 (en) 2018-08-01
EP2281603A2 (en) 2011-02-09
WO2004030760A2 (en) 2004-04-15
EP2281605B1 (en) 2020-06-03
CN1703258A (zh) 2005-11-30
US20040068297A1 (en) 2004-04-08
EP2281605A3 (en) 2011-06-08
PT2281602T (pt) 2018-10-23
PT2281603T (pt) 2020-09-08
ES2812499T3 (es) 2021-03-17
CA3100056A1 (en) 2004-04-15
PT2281605T (pt) 2020-09-04
DK3572123T3 (da) 2020-08-31
DK2281602T3 (da) 2018-10-01
CA2930736C (en) 2021-01-12
US20050240173A1 (en) 2005-10-27
EP3656441B1 (en) 2021-07-14
PT1545704T (pt) 2020-09-18
ES2812531T3 (es) 2021-03-17
DK2281604T3 (da) 2020-08-31
DK3656441T3 (da) 2021-08-09
CA2499845C (en) 2016-05-24
DK1545704T3 (da) 2020-09-07
EP3572123A1 (en) 2019-11-27
EP1545704A2 (en) 2005-06-29
HUE051374T2 (hu) 2021-03-01
ES2813059T3 (es) 2021-03-22
AU2003265066A1 (en) 2004-04-23
HUE051961T2 (hu) 2021-04-28
ES2881730T3 (es) 2021-11-30
US6868289B2 (en) 2005-03-15
EP2281602A1 (en) 2011-02-09
HUE055320T2 (hu) 2021-11-29
DK2281603T3 (da) 2020-08-31

Similar Documents

Publication Publication Date Title
DK2281604T3 (da) Apparat til behandling af en tumor med et elektrisk felt
DE60315068D1 (de) Apparat zum unterscheiden von polymorphen von monomorphen tachyarrhythmien
DK1663604T3 (da) Krebinetdannende apparat
DE602004010961D1 (de) Lithographischer Apparat
SE0202956L (sv) Apparat fär styrning av en anordning
DK1285199T3 (da) Apparat til behandling af affald
DE602004008009D1 (de) Lithographischer Apparat
NO20016146L (no) Apparat for terapi med elektrisk potensial
DE602004017411D1 (de) Lithographischer Apparat
FI20022150A (fi) Menetelmä kuonan käsittelemiseksi
DE60327985D1 (de) Apparat zur Leistungsübertragung
SE0201585D0 (sv) Apparat
SE0200349D0 (sv) Apparat
SE0302858D0 (sv) Apparat
SE0201091D0 (sv) Apparat
AU2003251208A8 (en) Apparatus for treating strip-shaped parts
SE0302265D0 (sv) Apparat
SE0302263D0 (sv) Apparat
SE0302182D0 (sv) apparat
SE0302264D0 (sv) Apparat
SE0302262D0 (sv) Apparat
SE0300677D0 (sv) Apparat
SE0300796D0 (sv) Apparat
SE0302389D0 (sv) Apparat
SE0301818D0 (sv) Apparat