DK2124947T3 - Doseringsskema for comt-inhibitorer - Google Patents

Doseringsskema for comt-inhibitorer

Info

Publication number
DK2124947T3
DK2124947T3 DK07834911.5T DK07834911T DK2124947T3 DK 2124947 T3 DK2124947 T3 DK 2124947T3 DK 07834911 T DK07834911 T DK 07834911T DK 2124947 T3 DK2124947 T3 DK 2124947T3
Authority
DK
Denmark
Prior art keywords
comt inhibitors
dosage scheme
dosage
scheme
comt
Prior art date
Application number
DK07834911.5T
Other languages
English (en)
Inventor
David Alexander Learmonth
Laszlo Erno Kiss
Pedro Nuno Leal Palma
Humberto Dos Santos Ferreira
Patrício Manuel Vieira Araújo Soares da SILVA
Original Assignee
Bial - Portela & Ca S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bial - Portela & Ca S A filed Critical Bial - Portela & Ca S A
Application granted granted Critical
Publication of DK2124947T3 publication Critical patent/DK2124947T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DK07834911.5T 2007-01-31 2007-10-10 Doseringsskema for comt-inhibitorer DK2124947T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07002091 2007-01-31
PCT/PT2007/000043 WO2008094053A1 (en) 2007-01-31 2007-10-10 Dosage regimen for comt inhibitors

Publications (1)

Publication Number Publication Date
DK2124947T3 true DK2124947T3 (da) 2017-11-06

Family

ID=38961862

Family Applications (2)

Application Number Title Priority Date Filing Date
DK07834911.5T DK2124947T3 (da) 2007-01-31 2007-10-10 Doseringsskema for comt-inhibitorer
DK12163797.9T DK2481410T3 (da) 2007-01-31 2007-10-10 Nitrocatecholderivater som COMT-inhibitorer indgivet i et specifikt dosisregime

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK12163797.9T DK2481410T3 (da) 2007-01-31 2007-10-10 Nitrocatecholderivater som COMT-inhibitorer indgivet i et specifikt dosisregime

Country Status (24)

Country Link
US (3) US8524746B2 (da)
EP (2) EP2481410B1 (da)
JP (1) JP5517629B2 (da)
KR (1) KR101522157B1 (da)
CN (1) CN101631548B (da)
AR (2) AR065098A1 (da)
AU (1) AU2007346018A1 (da)
BR (1) BRPI0721213B1 (da)
CA (1) CA2678391C (da)
CY (1) CY1118311T1 (da)
DK (2) DK2124947T3 (da)
ES (2) ES2597705T3 (da)
HR (1) HRP20161261T8 (da)
HU (1) HUE031317T2 (da)
IL (1) IL200020A (da)
LT (1) LT2481410T (da)
MX (1) MX2009008051A (da)
NO (1) NO20092905L (da)
PL (1) PL2481410T3 (da)
PT (2) PT2481410T (da)
RU (1) RU2518483C2 (da)
SI (1) SI2481410T1 (da)
WO (1) WO2008094053A1 (da)
ZA (1) ZA200905940B (da)

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AU2009277196B2 (en) * 2008-07-29 2015-06-18 Bial - Portela & Ca., S.A. Administration regime for nitrocatechols
PT2413912T (pt) * 2009-04-01 2019-06-11 Bial Portela & Ca Sa Formulações farmacêuticas compreendendo derivados de nitrocatecol e métodos para as produzir
AU2010231962B2 (en) * 2009-04-01 2015-05-21 Bial - Portela & Ca., S.A. Pharmaceutical formulations comprising nitrocatechol derivatives and methods of making the same
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US20140045900A1 (en) * 2011-02-11 2014-02-13 Bial-Portela & Ca, S.A. Administration regime for nitrocatechols
PL2791134T3 (pl) * 2011-12-13 2020-03-31 BIAL - PORTELA & Cª S.A. Związek chemiczny użyteczny jako związek pośredni do wytwarzania inhibitora katechol-o-metylotransferazy
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US9951057B2 (en) 2015-01-30 2018-04-24 Lieber Institute For Brain Development COMT inhibiting methods and compositions
CA3006189C (en) 2015-11-25 2023-12-19 Lieber Institute For Brain Development Comt inhibiting methods and compositions
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US20140045900A1 (en) 2011-02-11 2014-02-13 Bial-Portela & Ca, S.A. Administration regime for nitrocatechols
PL2791134T3 (pl) 2011-12-13 2020-03-31 BIAL - PORTELA & Cª S.A. Związek chemiczny użyteczny jako związek pośredni do wytwarzania inhibitora katechol-o-metylotransferazy

Also Published As

Publication number Publication date
JP5517629B2 (ja) 2014-06-11
US20130331416A1 (en) 2013-12-12
ES2644049T3 (es) 2017-11-27
PT2481410T (pt) 2016-10-18
AR065098A1 (es) 2009-05-13
ES2597705T3 (es) 2017-01-20
EP2124947B1 (en) 2017-07-19
IL200020A (en) 2016-07-31
BRPI0721213A2 (pt) 2014-03-18
CN101631548B (zh) 2014-08-27
CA2678391C (en) 2017-01-17
US20100113529A1 (en) 2010-05-06
HUE031317T2 (hu) 2017-07-28
NO20092905L (no) 2009-10-29
HRP20161261T8 (hr) 2016-12-30
DK2481410T3 (da) 2016-10-24
EP2481410A1 (en) 2012-08-01
SI2481410T1 (sl) 2017-01-31
US8524746B2 (en) 2013-09-03
US9745290B2 (en) 2017-08-29
WO2008094053A1 (en) 2008-08-07
PT2124947T (pt) 2017-10-25
AU2007346018A1 (en) 2008-08-07
BRPI0721213B1 (pt) 2021-11-09
CA2678391A1 (en) 2008-08-07
EP2124947A1 (en) 2009-12-02
CN101631548A (zh) 2010-01-20
EP2481410B1 (en) 2016-07-13
LT2481410T (lt) 2016-11-10
KR101522157B1 (ko) 2015-05-28
KR20090104859A (ko) 2009-10-06
ZA200905940B (en) 2010-05-26
PL2481410T3 (pl) 2017-03-31
IL200020A0 (en) 2010-04-15
CY1118311T1 (el) 2017-06-28
HRP20161261T1 (hr) 2016-12-02
RU2518483C2 (ru) 2014-06-10
US20160009699A1 (en) 2016-01-14
JP2011500506A (ja) 2011-01-06
MX2009008051A (es) 2009-08-12
AU2007346018A2 (en) 2011-04-21
RU2009132188A (ru) 2011-03-10
AR109590A2 (es) 2018-12-26

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