NO20092905L - Doseringsregime for COMT-ihibitorer - Google Patents

Doseringsregime for COMT-ihibitorer

Info

Publication number
NO20092905L
NO20092905L NO20092905A NO20092905A NO20092905L NO 20092905 L NO20092905 L NO 20092905L NO 20092905 A NO20092905 A NO 20092905A NO 20092905 A NO20092905 A NO 20092905A NO 20092905 L NO20092905 L NO 20092905L
Authority
NO
Norway
Prior art keywords
dosage regimen
comt inhibitors
medicament
day
dosage
Prior art date
Application number
NO20092905A
Other languages
English (en)
Norwegian (no)
Inventor
David Alexander Learmonth
Laszlo Erno Kiss
Pedro Nuno Leal Palma
Humberto Dos Santos Ferreira
Patricio Manuel Vieira Araujo Soares Da Silva
Original Assignee
Bial Portela & Ca Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bial Portela & Ca Sa filed Critical Bial Portela & Ca Sa
Publication of NO20092905L publication Critical patent/NO20092905L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
NO20092905A 2007-01-31 2009-08-28 Doseringsregime for COMT-ihibitorer NO20092905L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07002091 2007-01-31
PCT/PT2007/000043 WO2008094053A1 (en) 2007-01-31 2007-10-10 Dosage regimen for comt inhibitors

Publications (1)

Publication Number Publication Date
NO20092905L true NO20092905L (no) 2009-10-29

Family

ID=38961862

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20092905A NO20092905L (no) 2007-01-31 2009-08-28 Doseringsregime for COMT-ihibitorer

Country Status (24)

Country Link
US (3) US8524746B2 (da)
EP (2) EP2481410B1 (da)
JP (1) JP5517629B2 (da)
KR (1) KR101522157B1 (da)
CN (1) CN101631548B (da)
AR (2) AR065098A1 (da)
AU (1) AU2007346018A1 (da)
BR (1) BRPI0721213B1 (da)
CA (1) CA2678391C (da)
CY (1) CY1118311T1 (da)
DK (2) DK2481410T3 (da)
ES (2) ES2597705T3 (da)
HR (1) HRP20161261T8 (da)
HU (1) HUE031317T2 (da)
IL (1) IL200020A (da)
LT (1) LT2481410T (da)
MX (1) MX2009008051A (da)
NO (1) NO20092905L (da)
PL (1) PL2481410T3 (da)
PT (2) PT2124947T (da)
RU (1) RU2518483C2 (da)
SI (1) SI2481410T1 (da)
WO (1) WO2008094053A1 (da)
ZA (1) ZA200905940B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL169855A (en) * 2005-07-25 2014-05-28 Elta Systems Ltd A system and method for locating a receiver location
SI1907382T1 (sl) 2005-07-26 2015-10-30 Bial-Portela & Ca S.A., Nitrokateholni derivati kot inhibitorji COMT
EP1845097A1 (en) 2006-04-10 2007-10-17 Portela & Ca., S.A. Oxadiazole derivatives as COMT inhibitors
AU2007334436A1 (en) 2006-12-15 2008-06-26 Abbott Laboratories Novel oxadiazole compounds
LT2481410T (lt) 2007-01-31 2016-11-10 Bial - Portela & Ca., S.A. Nitrokatecholio dariniai kaip komt inhibitoriai vartojami konkrečiu dozavimo režimu
AU2009217865A1 (en) * 2008-02-28 2009-09-03 Bial - Portela & Ca., S.A. Pharmaceutical composition for poorly soluble drugs
JP2011514380A (ja) * 2008-03-17 2011-05-06 バイアル−ポルテラ アンド シーエー,エス.エー. 5−[3−(2,5−ジクロロ−4,6−ジメチル−1−オキシ−ピリジン−3−イル)[1,2,4]オキサジアゾール−5−イル]−3−ニトロベンゼン−1,2−ジオールの結晶形
MX360330B (es) * 2008-07-29 2018-10-30 Bial Portela & Ca Sa Regimen de administracion para nitrocatecoles.
AU2010231961B2 (en) * 2009-04-01 2015-05-21 Bial - Portela & Ca., S.A. Pharmaceutical formulations comprising nitrocatechol derivatives and methods of making thereof
BRPI1016132B8 (pt) * 2009-04-01 2021-05-25 Bial Portela & Ca Sa composição, formulação farmacêutica, processo de obtenção de uma formulação farmacêutica estável
WO2011069075A2 (en) * 2009-12-04 2011-06-09 Grant Jon E Treating impulse control disorders with catechol-o- methyl-transferase inhibitors
US20140045900A1 (en) * 2011-02-11 2014-02-13 Bial-Portela & Ca, S.A. Administration regime for nitrocatechols
JP6456143B2 (ja) 2011-12-13 2019-01-23 ノヴィファーマ,エス.アー. カテコール−o−メチル転移酵素阻害剤を調製するための中間体として有用な化学的化合物
RU2017120184A (ru) 2014-11-28 2018-12-28 БИАЛ - ПОРТЕЛА ЭНД Ка, С.А. Лекарства для замедления течения болезни паркинсона
WO2016123576A1 (en) 2015-01-30 2016-08-04 Lieber Institute For Brain Development Comt inhibiting methods and compositions
CA2975401A1 (en) * 2015-01-30 2016-08-04 Lieber Institute For Brain Development Comt inhibiting methods and compositions
PL3380471T3 (pl) 2015-11-25 2021-12-20 Lieber Institute Inc. Dba Lieber Institute For Brain Development Tetrahydro-8h-pirydo[1,2-a]pirazyn-8-ony jako inhibitory comt do leczenia chorób i zaburzeń neurodegeneracyjnych
WO2020072884A1 (en) 2018-10-05 2020-04-09 Neurocrine Biosciences, Inc. Methods for the administration of comt inhibitors
WO2020072886A1 (en) 2018-10-05 2020-04-09 Neurocrine Biosciences, Inc. Methods for the administration of comt inhibitors
USD912395S1 (en) * 2019-11-01 2021-03-09 Jondarius Brown Apparatus for storing earphones
GB202204798D0 (en) 2022-04-01 2022-05-18 Bial Portela & Ca Sa Prodrugs of opicapone

Family Cites Families (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US660753A (en) * 1899-11-27 1900-10-30 Ferdinand-Christoph Von Heydebrand Und Der Lasa Artificial fuel.
US1532178A (en) * 1921-07-25 1925-04-07 Louis A Godbold Lubricator
FR1260080A (fr) 1960-03-22 1961-05-05 Materiel De Forage Soc De Fab Trépan à molettes étanche
US3647809A (en) * 1968-04-26 1972-03-07 Chinoin Gyogyszer Es Vegyeszet Certain pyridyl-1 2 4-oxadiazole derivatives
US4022901A (en) * 1975-03-05 1977-05-10 E. R. Squibb & Sons, Inc. 3-Pyridinyl-5-isothiocyanophenyl oxadiazoles
US4264573A (en) 1979-05-21 1981-04-28 Rowell Laboratories, Inc. Pharmaceutical formulation for slow release via controlled surface erosion
US4386668A (en) * 1980-09-19 1983-06-07 Hughes Tool Company Sealed lubricated and air cooled rock bit bearing
US5236952A (en) * 1986-03-11 1993-08-17 Hoffmann-La Roche Inc. Catechol derivatives
DK175069B1 (da) 1986-03-11 2004-05-24 Hoffmann La Roche Pyrocatecholderivater
YU213587A (en) 1986-11-28 1989-06-30 Orion Yhtymae Oy Process for obtaining new pharmacologic active cateholic derivatives
DE3840954A1 (de) 1988-12-05 1990-06-07 Shell Int Research Herstellung von 2-chlornicotinsaeureestern
EP0462639A1 (en) 1990-06-05 1991-12-27 Shell Internationale Researchmaatschappij B.V. Preparation of 2-chloropyridine derivatives
ATE113202T1 (de) 1990-11-29 1994-11-15 Wei Ming Pharmaceutical Mfg Co Hilfsträger für direkte verpressung.
US5622976A (en) 1991-12-31 1997-04-22 Fujisawa Pharmaceutical Co., Ltd. Oxadiazole derivatives having acetylcholinesterase-inhibitory and muscarinic agonist activity
GB9419274D0 (en) * 1994-09-23 1994-11-09 Orion Yhtymae Oy New method for the preparation of 3,4-dihydroxy-5-nitrobenzaldehyde
DE19628617A1 (de) 1996-07-16 1998-01-22 Basf Ag Direkttablettierhilfsmittel
US6206110B1 (en) * 1996-09-09 2001-03-27 Smith International, Inc. Protected lubricant reservoir with pressure control for sealed bearing earth boring drill bit
JP2002526482A (ja) * 1998-09-18 2002-08-20 バーテックス ファーマシューティカルズ インコーポレイテッド p38のインヒビター
GB2344819A (en) 1998-12-18 2000-06-21 Portela & Ca Sa 2-Phenyl-1-(3,4-dihydroxy-5-nitrophenyl)-1-ethanones
FI109453B (fi) 1999-06-30 2002-08-15 Orion Yhtymae Oyj Farmaseuttinen koostumus
DK1210344T3 (da) 1999-08-19 2006-03-06 Nps Pharma Inc Heteropolycykliske forbindelser og anvendelser deraf som metabotrope glutamatreceptorantagonister
US6660753B2 (en) * 1999-08-19 2003-12-09 Nps Pharmaceuticals, Inc. Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
FI20000635A0 (fi) 2000-03-17 2000-03-17 Orion Yhtymae Oyj COMT-inhibiittoreiden käyttö analgeettina
SE0001438D0 (sv) 2000-04-18 2000-04-18 Axon Chemicals Bv New chemical compounds and their use in therapy
DE10029201A1 (de) 2000-06-19 2001-12-20 Basf Ag Verfahren zur Herstellung fester oraler Darreichungsformen mit retardierender Wirkstoffreisetzung
GB2363792A (en) * 2000-06-21 2002-01-09 Portela & Ca Sa Nitrocatechols
AU2001280126A1 (en) 2000-08-24 2002-03-04 Sagawa Express Co., Ltd. Card payment method for service charge concerning to physical distribution or transportation
CN1166626C (zh) 2000-08-30 2004-09-15 李凌松 三或四取代苯基化合物、其制备方法及应用
ES2334888T3 (es) 2000-11-28 2010-03-17 Zymogenetics, L.L.C. Receptor de citocina zcytor19.
CA2436739A1 (en) 2000-12-26 2002-07-04 Takeda Chemical Industries, Ltd. Combination agent
US20040097555A1 (en) * 2000-12-26 2004-05-20 Shinegori Ohkawa Concomitant drugs
NZ527691A (en) 2001-02-21 2007-01-26 Nps Pharma Inc Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists
JP2004534779A (ja) 2001-05-30 2004-11-18 エルジー ライフサイエンス リミテッド 疾病治療用プロテインキナーゼ阻害剤
US7041685B2 (en) * 2001-06-08 2006-05-09 Cytovia, Inc. Substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof
EP1408964B1 (en) 2001-07-26 2007-01-24 MERCK PATENT GmbH Use of 2- 5-(4-fluorophenyl)-3-pyridylmethylaminomethyl|-chromane and its physiologically acceptable salts
JP4379853B2 (ja) 2001-10-05 2009-12-09 惠民製藥股▲分▼有限公司 直接錠剤化用調合物および補助剤の調合方法
EP1581213A4 (en) * 2002-12-18 2008-11-19 Cytovia Inc 3,5-DISUBSTITUES-1,2,4-OXADIAZOLES AND ANALOGS AS ACTIVATORS OF CASPASES AND APOPTOSIS PROMOTERS, AND USE THEREOF
WO2005006945A2 (en) * 2003-07-03 2005-01-27 The Salk Institute For Biological Studies Methods for treating neural disorders and compounds useful therefor
US7226920B2 (en) 2003-08-06 2007-06-05 Vertex Pharmaceuticals Inc. Aminotriazole compounds useful as inhibitors of protein kinases
DE10338174A1 (de) 2003-08-20 2005-03-24 Lts Lohmann Therapie-Systeme Ag Transdermale Arzneimittelzubereitungen mit Wirkstoffkombinationen zur Behandlung der Parkinson-Krankheit
US7300406B2 (en) 2003-09-30 2007-11-27 Carter Vandette B Medical examination apparatus
GB0325956D0 (en) 2003-11-06 2003-12-10 Addex Pharmaceuticals Sa Novel compounds
US7531556B2 (en) * 2004-04-28 2009-05-12 Vertex Pharmaceuticals Incorporated Compositions useful as inhibitors of rock and other protein kinases
GB0510143D0 (en) 2005-05-18 2005-06-22 Addex Pharmaceuticals Sa Novel compounds A1
EP1812070B1 (en) 2004-11-10 2013-10-02 Orion Corporation Treatment of restless legs syndrome
EP1827453A1 (en) 2004-12-06 2007-09-05 Themis Laboratories Private Limited Sulfonylurea compositions and a process for its preparation
US20080051441A1 (en) * 2004-12-28 2008-02-28 Astrazeneca Ab Aryl Sulphonamide Modulators
EP1833804A1 (en) 2004-12-28 2007-09-19 AstraZeneca AB Aryl sulphonamide modulators
AU2006239418A1 (en) 2005-04-26 2006-11-02 Neurosearch A/S Novel oxadiazole derivatives and their medical use
US20060257473A1 (en) 2005-05-11 2006-11-16 Porranee Puranajoti Extended release tablet
GB0510139D0 (en) * 2005-05-18 2005-06-22 Addex Pharmaceuticals Sa Novel compounds B1
EP2298734A3 (en) 2005-06-03 2011-07-13 Abbott Laboratories Cyclobutyl amine derivatives
JP2007024970A (ja) 2005-07-12 2007-02-01 Miyakawa:Kk 液晶表示装置の開口効率を上昇させるための樹脂レンズ製造法及びその製造装置
US20090000437A1 (en) 2005-07-14 2009-01-01 Provo Craft And Novelty, Inc. Methods for Cutting
GB0515327D0 (en) * 2005-07-26 2005-08-31 Portela & Ca Sa Comt inhibitors
SI1907382T1 (sl) 2005-07-26 2015-10-30 Bial-Portela & Ca S.A., Nitrokateholni derivati kot inhibitorji COMT
FR2889525A1 (fr) * 2005-08-04 2007-02-09 Palumed Sa Nouveaux derives de polyquinoleines et leur utilisation therapeutique.
US20070048384A1 (en) * 2005-08-26 2007-03-01 Joerg Rosenberg Pharmaceutical compositions
EP1954137A4 (en) * 2005-11-18 2008-12-17 Janssen Pharmaceutica Nv 2-KETO-OXAZOLE AS MODULATORS OF FATTY ACID AMIDHYDROLASE
EP1956013B1 (en) * 2005-11-30 2016-04-13 Fujifilm RI Pharma Co., Ltd. Diagnostic and remedy for disease caused by amyloid aggregation and/or deposition
GB0606774D0 (en) 2006-04-03 2006-05-10 Novartis Ag Organic compounds
EP1845097A1 (en) * 2006-04-10 2007-10-17 Portela & Ca., S.A. Oxadiazole derivatives as COMT inhibitors
PE20080906A1 (es) 2006-08-17 2008-07-05 Kemia Inc Derivados heteroarilo como inhibidores de citocina
US8486979B2 (en) * 2006-12-12 2013-07-16 Abbvie Inc. 1,2,4 oxadiazole compounds and methods of use thereof
US20080167286A1 (en) * 2006-12-12 2008-07-10 Abbott Laboratories Pharmaceutical compositions and their methods of use
LT2481410T (lt) 2007-01-31 2016-11-10 Bial - Portela & Ca., S.A. Nitrokatecholio dariniai kaip komt inhibitoriai vartojami konkrečiu dozavimo režimu
WO2009029632A1 (en) 2007-08-27 2009-03-05 Helicon Therapeutics, Inc. Therapeutic isoxazole compounds
AU2009217865A1 (en) * 2008-02-28 2009-09-03 Bial - Portela & Ca., S.A. Pharmaceutical composition for poorly soluble drugs
JP2011514380A (ja) 2008-03-17 2011-05-06 バイアル−ポルテラ アンド シーエー,エス.エー. 5−[3−(2,5−ジクロロ−4,6−ジメチル−1−オキシ−ピリジン−3−イル)[1,2,4]オキサジアゾール−5−イル]−3−ニトロベンゼン−1,2−ジオールの結晶形
MX360330B (es) 2008-07-29 2018-10-30 Bial Portela & Ca Sa Regimen de administracion para nitrocatecoles.
BRPI1016132B8 (pt) 2009-04-01 2021-05-25 Bial Portela & Ca Sa composição, formulação farmacêutica, processo de obtenção de uma formulação farmacêutica estável
AU2010231961B2 (en) 2009-04-01 2015-05-21 Bial - Portela & Ca., S.A. Pharmaceutical formulations comprising nitrocatechol derivatives and methods of making thereof
EA026419B1 (ru) 2010-03-04 2017-04-28 Орион Корпорейшн Применение леводопы, карбидопы и энтакапона для лечения болезни паркинсона
US20140045900A1 (en) 2011-02-11 2014-02-13 Bial-Portela & Ca, S.A. Administration regime for nitrocatechols
JP6456143B2 (ja) 2011-12-13 2019-01-23 ノヴィファーマ,エス.アー. カテコール−o−メチル転移酵素阻害剤を調製するための中間体として有用な化学的化合物

Also Published As

Publication number Publication date
PL2481410T3 (pl) 2017-03-31
MX2009008051A (es) 2009-08-12
HRP20161261T1 (hr) 2016-12-02
JP5517629B2 (ja) 2014-06-11
BRPI0721213A2 (pt) 2014-03-18
ES2597705T3 (es) 2017-01-20
ES2644049T3 (es) 2017-11-27
KR20090104859A (ko) 2009-10-06
US20160009699A1 (en) 2016-01-14
CA2678391C (en) 2017-01-17
EP2481410B1 (en) 2016-07-13
HUE031317T2 (hu) 2017-07-28
ZA200905940B (en) 2010-05-26
WO2008094053A1 (en) 2008-08-07
EP2124947A1 (en) 2009-12-02
JP2011500506A (ja) 2011-01-06
CN101631548A (zh) 2010-01-20
CN101631548B (zh) 2014-08-27
RU2009132188A (ru) 2011-03-10
AU2007346018A1 (en) 2008-08-07
US9745290B2 (en) 2017-08-29
KR101522157B1 (ko) 2015-05-28
US20100113529A1 (en) 2010-05-06
AR109590A2 (es) 2018-12-26
CA2678391A1 (en) 2008-08-07
US20130331416A1 (en) 2013-12-12
PT2124947T (pt) 2017-10-25
US8524746B2 (en) 2013-09-03
LT2481410T (lt) 2016-11-10
IL200020A (en) 2016-07-31
DK2124947T3 (da) 2017-11-06
BRPI0721213B1 (pt) 2021-11-09
AR065098A1 (es) 2009-05-13
EP2124947B1 (en) 2017-07-19
HRP20161261T8 (hr) 2016-12-30
IL200020A0 (en) 2010-04-15
PT2481410T (pt) 2016-10-18
AU2007346018A2 (en) 2011-04-21
EP2481410A1 (en) 2012-08-01
SI2481410T1 (sl) 2017-01-31
RU2518483C2 (ru) 2014-06-10
DK2481410T3 (da) 2016-10-24
CY1118311T1 (el) 2017-06-28

Similar Documents

Publication Publication Date Title
NO20092905L (no) Doseringsregime for COMT-ihibitorer
MX2020004467A (es) Metodos para el tratamiento o la prevencion del asma mediante la administracion de antagonista de il-4r.
NI200900106A (es) Inhibidores de la actividad de la akt.
BR112014004560A2 (pt) compostos e composições como inibidores de c-kit quinase
PH12016501750A1 (en) Human plasma kallikrein inhibitors
MA32393B1 (fr) Composés et compositions servant d'inhibiteurs de kinases
MX2016013529A (es) Derivados de amidas y sales farmaceuticamente aceptables de los mismos, método de preparación de los mismos y aplicación médica de los mismos.
BR112014004504A2 (pt) "composto como inibidor de c-kit cinase, seu uso, composição farmacêutica, e medicamento para o tratamento de uma doença mediada por uma cinase"
BR112014004465A2 (pt) compostos e composições como inibidores de pdgfr cinase
MX2009007944A (es) Compuestos y composiciones de purina como inhibidores de quinasa para el tratamiento de enfermedades relacionadas con plasmodium.
BR112013021638A2 (pt) "compostos inibidores de trk, seu uso e composições que os compreendem"
NO20085100L (no) Nye forbindelser
BR112015018168A2 (pt) inibidores de rock suaves
BR112015010396A2 (pt) terapia de combinação
MY166890A (en) Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
EA202193019A1 (ru) Лечение наследственного ангионевротического отека
BR112019024322A2 (pt) Compostos e composições terapêuticos e métodos de uso dos mesmos
CR20190300A (es) Formas de administración farmacéutica que contienen inhibidores de canales task-1 y task-3 y su uso para el tratamiento de trastornos respiratorios
CO2021015793A2 (es) Métodos para tratar o prevenir el asma mediante la administración un antagonista de il-33
MX2021010297A (es) Inhibidores de calicreina plasmatica humana.
BR112017022158A2 (pt) compostos, composições farmacêuticas e uso de um composto
BR112017010599A2 (pt) análogos de ureia ligada substituída como moduladores sirtuin
BR112021021826A2 (pt) Terapias de combinação compreendendo os inibidores de apremilast e tyk2
BR112015000808A2 (pt) regime de dosagem para inibidores de janus quinase (jak)
BR112013027241A2 (pt) "composto inibidor de rock, composição que o compreende e seus usos"

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application