CR10831A - INHIBIDORES ESPIRO CETONA DE ACETIL-CoA CARBOXILASA - Google Patents
INHIBIDORES ESPIRO CETONA DE ACETIL-CoA CARBOXILASAInfo
- Publication number
- CR10831A CR10831A CR10831A CR10831A CR10831A CR 10831 A CR10831 A CR 10831A CR 10831 A CR10831 A CR 10831A CR 10831 A CR10831 A CR 10831A CR 10831 A CR10831 A CR 10831A
- Authority
- CR
- Costa Rica
- Prior art keywords
- ketona
- carboxilasa
- espiro
- acetil
- coa
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
- C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/39—Heterocyclic compounds having sulfur as a ring hetero atom having oxygen in the same ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US86177906P | 2006-11-29 | 2006-11-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
CR10831A true CR10831A (es) | 2009-06-18 |
Family
ID=39126209
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CR10831A CR10831A (es) | 2006-11-29 | 2009-05-28 | INHIBIDORES ESPIRO CETONA DE ACETIL-CoA CARBOXILASA |
Country Status (23)
Country | Link |
---|---|
US (1) | US20090270435A1 (es) |
EP (1) | EP2097420B1 (es) |
JP (1) | JP2010511035A (es) |
KR (1) | KR20090083956A (es) |
CN (1) | CN101541809A (es) |
AP (1) | AP2009004880A0 (es) |
AT (1) | ATE552262T1 (es) |
AU (1) | AU2007326950B2 (es) |
BR (1) | BRPI0721053A2 (es) |
CA (1) | CA2670422C (es) |
CO (1) | CO6180424A2 (es) |
CR (1) | CR10831A (es) |
EA (1) | EA200900613A1 (es) |
EC (1) | ECSP099371A (es) |
IL (1) | IL198779A0 (es) |
MA (1) | MA30932B1 (es) |
MX (1) | MX2009005604A (es) |
NO (1) | NO20091889L (es) |
RS (1) | RS20090249A (es) |
SV (1) | SV2009003281A (es) |
TN (1) | TN2009000204A1 (es) |
WO (1) | WO2008065508A1 (es) |
ZA (1) | ZA200903268B (es) |
Families Citing this family (67)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PE20081559A1 (es) * | 2007-01-12 | 2008-11-20 | Merck & Co Inc | DERIVADOS DE ESPIROCROMANONA SUSTITUIDOS COMO INHIBIDORES DE ACETIL CoA CARBOXILASA |
WO2008088692A2 (en) | 2007-01-12 | 2008-07-24 | Merck & Co., Inc. | Spirochromanon derivatives |
CN100550853C (zh) * | 2007-01-25 | 2009-10-14 | 华为技术有限公司 | 一种基于输出队列的流控实现方法及装置 |
DE102007028521A1 (de) * | 2007-06-21 | 2008-12-24 | Merck Patent Gmbh | Indazolamidderivate |
EP2297164A1 (en) * | 2008-05-28 | 2011-03-23 | Pfizer Inc. | Pyrazolospiroketone acetyl-coa carboxylase inhibitors |
ES2545231T3 (es) * | 2008-05-28 | 2015-09-09 | Pfizer Inc. | Inhibidores de pirazoloespirocetona acetil-CoA carboxilasa |
EP2307422B1 (en) * | 2008-07-04 | 2014-03-26 | Msd K.K. | Novel spirochromanone carboxylic acids |
US8110570B2 (en) | 2008-07-14 | 2012-02-07 | Cropsolution, Inc. | Modulators of acetyl-coenzyme A carboxylase and methods of use thereof |
DE102008038222A1 (de) | 2008-08-18 | 2010-02-25 | Merck Patent Gmbh | Indazol-5-carbonsäurehydrazid-derivate |
EP2184276A1 (en) | 2008-11-07 | 2010-05-12 | Universite Paul Cezanne Aix-Marseille Iii | Process to prepare new substituted 1H-Benzo(d) imidazol-2(3h)-Ones, New intermediates and their use as bace 1 inhibitors |
EP2499140A1 (en) * | 2009-11-10 | 2012-09-19 | Pfizer Inc. | N2-pyrazolospiroketone acetyl-coa carboxylase inhibitors |
KR101478517B1 (ko) | 2009-11-10 | 2015-01-02 | 화이자 인코포레이티드 | N1-피라졸로스피로케톤 아세틸-coa 카복실라아제 억제제 |
MX2012010772A (es) | 2010-03-19 | 2012-11-06 | Pfizer | Derivados de 2,3-dihidro-1h-inden-1-il-2,7-diazaspiro[3,5]nonano y su uso como antagonistas o agonistas inversos del receptor de grelina. |
WO2011140425A1 (en) | 2010-05-06 | 2011-11-10 | Vertex Pharmaceuticals Incorporated | Heterocyclic chromene-spirocyclic piperidine amides as modulators of ion channels |
WO2011157827A1 (de) | 2010-06-18 | 2011-12-22 | Sanofi | Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen |
ES2602111T3 (es) | 2010-09-30 | 2017-02-17 | Pfizer Inc | Inhibidores de acetil-CoA carboxilasas de N1-pirazoloespirocetona |
PL2632925T3 (pl) | 2010-10-29 | 2015-10-30 | Pfizer | N1/N2-laktamowe inhibitory karboksylazy acetylo-CoA |
SI2670752T1 (sl) | 2011-02-02 | 2016-10-28 | Vertex Pharmaceuticals Incorporated | Pirolopirazin-spirociklični piperidin amidi kot modulatorji ionskih kanalčkov |
AU2012217616B2 (en) * | 2011-02-18 | 2017-03-02 | Vertex Pharmaceuticals Incorporated | Chroman - spirocyclic piperidine amides as modulators of ion channels |
JP6088443B2 (ja) | 2011-03-14 | 2017-03-01 | バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated | イオンチャネルのモジュレーターとしてのモルホリン−スピロ環式ピペリジンアミド |
CN106117205B (zh) | 2011-04-22 | 2018-09-21 | 辉瑞大药厂 | 用作乙酰辅酶a羧化酶抑制剂类的吡唑并螺酮衍生物 |
KR101953407B1 (ko) | 2011-07-08 | 2019-02-28 | 바이엘 인텔렉쳐 프로퍼티 게엠베하 | 2-아미노-5-시아노-n,3-디메틸벤즈아미드의 제조 방법 |
CA2841757A1 (en) | 2011-07-15 | 2013-01-24 | Etzer Darout | Gpr 119 modulators |
KR20140023441A (ko) | 2011-07-22 | 2014-02-26 | 화이자 인코포레이티드 | 퀴놀린일 글루카곤 수용체 조절제 |
PT2746265E (pt) | 2011-08-18 | 2016-03-11 | Nippon Shinyaku Co Ltd | Derivado heterocíclico como inibidor de pronstaglandina-sintase microssomal (mpge) |
JP6043355B2 (ja) | 2011-08-31 | 2016-12-14 | ファイザー・インク | ヘキサヒドロピラノ[3,4−d][1,3]チアジン−2−アミン化合物 |
CA2853024C (en) | 2011-11-11 | 2017-08-22 | Pfizer Inc. | 2-thiopyrimidinones |
WO2013150416A1 (en) | 2012-04-06 | 2013-10-10 | Pfizer Inc. | Diacylglycerol acyltransferase 2 inhibitors |
US8889730B2 (en) | 2012-04-10 | 2014-11-18 | Pfizer Inc. | Indole and indazole compounds that activate AMPK |
JP6110937B2 (ja) | 2012-05-04 | 2017-04-05 | ファイザー・インク | APP、BACE1、およびBACE2の阻害剤としての複素環式置換ヘキサヒドロピラノ[3,4−d][1,3]チアジン−2−アミン化合物 |
US9260455B2 (en) | 2012-09-20 | 2016-02-16 | Pfizer Inc. | Alkyl-substituted hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds |
WO2014091352A1 (en) | 2012-12-11 | 2014-06-19 | Pfizer Inc. | Hexahydropyrano [3,4-d][1,3]thiazin-2-amine compounds as inhibitors of bace1 |
CA2893333C (en) | 2012-12-19 | 2017-10-24 | Pfizer Inc. | Carbocyclic-and heterocyclic-substituted hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds |
JP2016507551A (ja) | 2013-02-13 | 2016-03-10 | ファイザー・インク | ヘテロアリール置換ヘキサヒドロピラノ[3,4−d][1,3]チアジン−2−アミン化合物 |
US9233981B1 (en) | 2013-02-15 | 2016-01-12 | Pfizer Inc. | Substituted phenyl hexahydropyrano[3,4-d][1,3]thiazin-2-amine compounds |
CA2926568C (en) | 2013-10-09 | 2017-09-05 | Pfizer Inc. | Antagonists of prostaglandin ep3 receptor |
TR201809388T4 (tr) | 2014-03-17 | 2018-07-23 | Pfizer | Metabolik ve ilişkili hastalıkların tedavisinde kullanılmaya yönelik diasilgliserol asiltransferaz 2 inhibitörleri. |
EP3126330B1 (en) | 2014-04-04 | 2019-02-27 | Pfizer Inc | Bicyclic-fused heteroaryl or aryl compounds and their use as irak4 inhibitors |
MX2016013329A (es) | 2014-04-10 | 2017-01-26 | Pfizer | 2-amino-6-metil-4,4a,5,6-tetrahidropirano[3,4-d][1,3]tiazin-8a(8h )-il-1,3-tiazol-4-ilamidas. |
WO2016092413A1 (en) | 2014-12-10 | 2016-06-16 | Pfizer Inc. | Indole and indazole compounds that activate ampk |
EP3237401B1 (en) | 2014-12-22 | 2019-03-06 | Pfizer Inc | Antagonists of prostaglandin ep3 receptor |
BR112017022340A2 (pt) | 2015-05-05 | 2018-07-10 | Pfizer | 2-tiopirimidinonas |
CA2987179C (en) | 2015-05-29 | 2020-08-25 | Pfizer Inc. | Heterocyclic compounds as inhibitors of vanin-1 enzyme |
HUE051898T2 (hu) | 2015-06-17 | 2021-03-29 | Pfizer | Triciklusos vegyületek és alkalmazásuk foszfodiészteráz inhibitorokként |
WO2016203335A1 (en) | 2015-06-18 | 2016-12-22 | Pfizer Inc. | Novel pyrido[2,3-b]pyrazinones as bet-family bromodomain inhibitors |
CA2995153A1 (en) | 2015-08-13 | 2017-02-16 | Pfizer Inc. | Bicyclic-fused heteroaryl or aryl compounds |
EP3858825A1 (en) | 2015-08-27 | 2021-08-04 | Pfizer Inc. | Bicyclic-fused heteroaryl compounds as irak4 modulators |
WO2017037567A1 (en) | 2015-09-03 | 2017-03-09 | Pfizer Inc. | Regulators of frataxin |
EP3353182A1 (en) | 2015-09-24 | 2018-08-01 | Pfizer Inc | Tetrahydropyrano[3,4-d][1,3]oxazin derivatives and their use as bace inhibitors |
AU2016325665A1 (en) | 2015-09-24 | 2018-03-08 | Pfizer Inc. | N-[2-(2-amino-6,6-disubstituted-4, 4a, 5, 6-tetrahydropyrano [3,4-d][1,3] thiazin-8a (8h)-yl) -1, 3-thiazol-4-yl] amides |
EP3353174A1 (en) | 2015-09-24 | 2018-08-01 | Pfizer Inc | N-[2-(3-amino-2,5-dimethyl-1,1-dioxido-5,6-dihydro-2h-1,2,4-thiadiazin-5-yl)-1,3-thiazol-4-yl]amides useful as bace inhibitors |
JP6503515B2 (ja) | 2015-12-29 | 2019-04-17 | ファイザー・インク | ケトヘキソキナーゼ阻害薬としての置換3−アザビシクロ[3.1.0]ヘキサン |
SG11201811161YA (en) | 2016-07-14 | 2019-01-30 | Pfizer | Novel pyrimidine carboxamides as inhibitors of vanin-1 enzyme |
AR109179A1 (es) | 2016-08-19 | 2018-11-07 | Pfizer | Inhibidores de diacilglicerol aciltransferasa 2 |
WO2019133445A1 (en) | 2017-12-28 | 2019-07-04 | Inception Ibd, Inc. | Aminothiazoles as inhibitors of vanin-1 |
CN108658938B (zh) * | 2018-06-15 | 2021-03-23 | 上海现代制药股份有限公司 | 一种甲磺酸达比加群酯工艺杂质的合成方法 |
CN108774242B (zh) * | 2018-08-22 | 2020-10-27 | 牡丹江医学院 | 一种防治冠心病的药物及其制备方法 |
MX2021002428A (es) | 2018-08-31 | 2023-01-02 | Pfizer | Combinaciones para tratamiento de ehna/ehgna y enfermedades relacionadas. |
CN109400618B (zh) * | 2018-11-09 | 2021-08-10 | 中国药科大学 | 一种色满衍生物及其制备方法和应用 |
WO2020102575A1 (en) | 2018-11-16 | 2020-05-22 | Inception Ibd, Inc. | Heterocyclic aminothiazoles and uses thereof |
CN109809992A (zh) * | 2019-02-16 | 2019-05-28 | 安徽华胜医药科技有限公司 | 一种2-(2-氟-3-甲氧基苯基)-2-羟基乙酸乙酯的合成方法 |
EP3972596A1 (en) | 2019-05-20 | 2022-03-30 | Pfizer Inc. | Combinations comprising benzodioxol as glp-1r agonists for use in the treatment of nash/nafld and related diseases |
CN110128347A (zh) * | 2019-06-17 | 2019-08-16 | 韶远科技(上海)有限公司 | 一种1-甲基-1h-吲唑-6-甲酸的合成方法 |
GB201910304D0 (en) | 2019-07-18 | 2019-09-04 | Ctxt Pty Ltd | Compounds |
WO2022095971A1 (zh) * | 2020-11-06 | 2022-05-12 | 上海医药集团股份有限公司 | 一种螺杂环类化合物、其制备方法及应用 |
WO2023169456A1 (en) | 2022-03-09 | 2023-09-14 | Gasherbrum Bio , Inc. | Heterocyclic glp-1 agonists |
WO2023198140A1 (en) | 2022-04-14 | 2023-10-19 | Gasherbrum Bio, Inc. | Heterocyclic glp-1 agonists |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL96507A0 (en) * | 1989-12-08 | 1991-08-16 | Merck & Co Inc | Nitrogen-containing spirocycles and pharmaceutical compositions containing them |
JP2001516330A (ja) * | 1995-06-06 | 2001-09-25 | メルク エンド カンパニー インコーポレーテッド | アルファ1aアドレナリンレセプターアンタゴニスト |
WO2002020509A2 (de) * | 2000-09-06 | 2002-03-14 | Bayer Aktiengesellschaft | Arzneimittel gegen virale erkrankungen |
WO2004092179A1 (ja) * | 2003-04-14 | 2004-10-28 | Nippon Soda Co. Ltd. | スピロ誘導体、製造法および抗酸化薬 |
JP2005119987A (ja) * | 2003-10-15 | 2005-05-12 | Ajinomoto Co Inc | アシルスルホンアミド誘導体 |
EP1802623A1 (en) * | 2004-10-12 | 2007-07-04 | Novo Nordisk A/S | 11beta-hydroxysteroid dehydrogenase type 1 active spiro compounds |
WO2006117669A1 (en) * | 2005-05-03 | 2006-11-09 | Pfizer Inc. | Amide resorcinol compounds |
US7935712B2 (en) * | 2005-07-19 | 2011-05-03 | Merck Sharp & Dohme Corp. | Spirochromanone derivatives as acetyl coenzyme A carboxylase (ACC) inhibitors |
-
2007
- 2007-11-16 WO PCT/IB2007/003639 patent/WO2008065508A1/en active Application Filing
- 2007-11-16 CN CNA2007800442537A patent/CN101541809A/zh active Pending
- 2007-11-16 AU AU2007326950A patent/AU2007326950B2/en not_active Expired - Fee Related
- 2007-11-16 MX MX2009005604A patent/MX2009005604A/es not_active Application Discontinuation
- 2007-11-16 BR BRPI0721053-1A patent/BRPI0721053A2/pt not_active IP Right Cessation
- 2007-11-16 JP JP2009538803A patent/JP2010511035A/ja active Pending
- 2007-11-16 AT AT07825738T patent/ATE552262T1/de active
- 2007-11-16 EA EA200900613A patent/EA200900613A1/ru unknown
- 2007-11-16 US US12/514,596 patent/US20090270435A1/en not_active Abandoned
- 2007-11-16 KR KR1020097013481A patent/KR20090083956A/ko not_active Application Discontinuation
- 2007-11-16 RS RSP-2009/0249A patent/RS20090249A/sr unknown
- 2007-11-16 EP EP07825738A patent/EP2097420B1/en active Active
- 2007-11-16 CA CA2670422A patent/CA2670422C/en not_active Expired - Fee Related
- 2007-11-16 AP AP2009004880A patent/AP2009004880A0/xx unknown
-
2009
- 2009-05-12 ZA ZA200903268A patent/ZA200903268B/xx unknown
- 2009-05-14 IL IL198779A patent/IL198779A0/en unknown
- 2009-05-14 NO NO20091889A patent/NO20091889L/no not_active Application Discontinuation
- 2009-05-22 TN TNP2009000204A patent/TN2009000204A1/fr unknown
- 2009-05-28 CR CR10831A patent/CR10831A/es not_active Application Discontinuation
- 2009-05-28 CO CO09054954A patent/CO6180424A2/es not_active Application Discontinuation
- 2009-05-29 MA MA31936A patent/MA30932B1/fr unknown
- 2009-05-29 SV SV2009003281A patent/SV2009003281A/es not_active Application Discontinuation
- 2009-05-29 EC EC2009009371A patent/ECSP099371A/es unknown
Also Published As
Publication number | Publication date |
---|---|
JP2010511035A (ja) | 2010-04-08 |
AU2007326950B2 (en) | 2010-10-14 |
US20090270435A1 (en) | 2009-10-29 |
WO2008065508A1 (en) | 2008-06-05 |
ATE552262T1 (de) | 2012-04-15 |
CA2670422A1 (en) | 2008-06-05 |
SV2009003281A (es) | 2010-08-17 |
NO20091889L (no) | 2009-06-17 |
AP2009004880A0 (en) | 2009-06-30 |
MA30932B1 (fr) | 2009-11-02 |
MX2009005604A (es) | 2009-06-08 |
ZA200903268B (en) | 2010-07-28 |
EA200900613A1 (ru) | 2009-10-30 |
RS20090249A (en) | 2010-06-30 |
EP2097420B1 (en) | 2012-04-04 |
EP2097420A1 (en) | 2009-09-09 |
KR20090083956A (ko) | 2009-08-04 |
BRPI0721053A2 (pt) | 2014-07-29 |
CA2670422C (en) | 2011-09-06 |
ECSP099371A (es) | 2009-06-30 |
TN2009000204A1 (fr) | 2010-10-18 |
CN101541809A (zh) | 2009-09-23 |
IL198779A0 (en) | 2010-02-17 |
CO6180424A2 (es) | 2010-07-19 |
AU2007326950A1 (en) | 2008-06-05 |
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