DK20979A - 4-amino-5-alkylsulfonyl-0-anisamid-derivater samt fremgangsmaade til fremstilling deraf - Google Patents

4-amino-5-alkylsulfonyl-0-anisamid-derivater samt fremgangsmaade til fremstilling deraf

Info

Publication number
DK20979A
DK20979A DK20979A DK20979A DK20979A DK 20979 A DK20979 A DK 20979A DK 20979 A DK20979 A DK 20979A DK 20979 A DK20979 A DK 20979A DK 20979 A DK20979 A DK 20979A
Authority
DK
Denmark
Prior art keywords
alkylsulphonyl
procedures
amino
preparation
anisamide
Prior art date
Application number
DK20979A
Other languages
English (en)
Other versions
DK158346C (da
DK158346B (da
Inventor
M Thominet
J Acher
J C Monier
Original Assignee
Ile De France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ile De France filed Critical Ile De France
Publication of DK20979A publication Critical patent/DK20979A/da
Publication of DK158346B publication Critical patent/DK158346B/da
Application granted granted Critical
Publication of DK158346C publication Critical patent/DK158346C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
DK020979A 1978-01-20 1979-01-18 Analogifremgangsmaade til fremstilling af 4-amino-5-alkylsulfonyl-o-anisamid-derivater samt 2-methoxy-4-amino-5-alkylsulfonylbenzoesyrer til anvendelse som mellemprodukter ved fremgangsmaaden DK158346C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7801632 1978-01-20
FR7801632A FR2415099A1 (fr) 1978-01-20 1978-01-20 Nouveaux derives de 4-amino-5-alkylsulfonyl ortho-anisamides, leurs procedes de preparation et leur application comme psychotropes

Publications (3)

Publication Number Publication Date
DK20979A true DK20979A (da) 1979-07-21
DK158346B DK158346B (da) 1990-05-07
DK158346C DK158346C (da) 1990-10-08

Family

ID=9203689

Family Applications (1)

Application Number Title Priority Date Filing Date
DK020979A DK158346C (da) 1978-01-20 1979-01-18 Analogifremgangsmaade til fremstilling af 4-amino-5-alkylsulfonyl-o-anisamid-derivater samt 2-methoxy-4-amino-5-alkylsulfonylbenzoesyrer til anvendelse som mellemprodukter ved fremgangsmaaden

Country Status (42)

Country Link
US (2) US4294828A (da)
JP (1) JPS6049192B2 (da)
AR (2) AR221354A1 (da)
AT (1) AT377977B (da)
AU (1) AU528561B2 (da)
BE (1) BE872585A (da)
BG (2) BG31497A3 (da)
CA (1) CA1101430A (da)
CH (1) CH637927A5 (da)
CS (1) CS226181B2 (da)
CY (1) CY1201A (da)
DD (1) DD141520A5 (da)
DE (1) DE2901181C2 (da)
DK (1) DK158346C (da)
EG (1) EG14045A (da)
ES (2) ES476755A1 (da)
FI (1) FI71126C (da)
FR (1) FR2415099A1 (da)
GB (2) GB2012765B (da)
GR (1) GR64431B (da)
HK (1) HK12184A (da)
HU (1) HU179793B (da)
IE (1) IE47798B1 (da)
IL (1) IL56411A (da)
IN (1) IN150226B (da)
IT (1) IT1164655B (da)
LU (1) LU80786A1 (da)
MC (1) MC1232A1 (da)
MX (2) MX7623E (da)
NL (1) NL191707C (da)
NO (1) NO151320C (da)
NZ (1) NZ189378A (da)
OA (1) OA06156A (da)
PH (2) PH15725A (da)
PL (2) PL118151B1 (da)
PT (1) PT69068A (da)
RO (2) RO76393A (da)
SE (2) SE448874B (da)
SU (1) SU820659A3 (da)
YU (2) YU42172B (da)
ZA (1) ZA79219B (da)
ZM (1) ZM579A1 (da)

Families Citing this family (44)

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FR2440946A2 (fr) * 1978-01-20 1980-06-06 Ile De France Nouveaux benzamides heterocycliques substitues, leurs procedes de preparation et leur application comme modificateurs du comportement
NZ199080A (en) * 1980-12-12 1984-07-31 Beecham Group Ltd 2-alkoxy-4-amino-5-alkylsulphonyl-n-(3beta-(8-hydrocarbyl-8-azabicyclo (3,2,1)octyl))benzamides
FR2550447B1 (fr) * 1983-08-10 1986-01-17 Ile De France Application du n-(ally-2-pyrrolidinylmethyl) 2-methoxy 4-amino 5-methylsulfamoyl benzamide comme antiagregant plaquettaire
FR2574795B1 (fr) * 1984-12-18 1987-11-20 Ile De France Nouveau procede industriel de synthese du n-((1'-allyl 2'-pyrrolidinyl) methyl) 2-methoxy 4,5-azimido benzamide
FR2584401B1 (fr) * 1985-07-04 1987-11-20 Ile De France Nouveau benzamide, son procede de preparation et son application dans le domaine therapeutique
US5227388A (en) * 1989-12-26 1993-07-13 Hoechst-Roussel Pharmaceuticals Incorporated Thienobenzoxepins and naphthothiophenes
US5260319A (en) * 1989-12-26 1993-11-09 Hoechst-Roussel Pharmaceuticals Incorporated Thienobenzoxepins and naphthothiophenes
FR2678266A1 (fr) * 1991-06-28 1992-12-31 Delagrange Laboratoires Nouveaux derives de 2-hydroxy 4-amino 5-ethylsulfonyl benzamide utiles comme anxiolytiques.
FR2699533A1 (fr) * 1992-12-21 1994-06-24 Mouhtaram Mohamed Dérivés de N-((1,4-dialkyl-6-arylpipérazine-2-yl)méthyl)benzamides. (Isomères cis et trans) Propriétés pharmacologiques et applications.
FR2753376B1 (fr) * 1996-09-18 1998-10-16 Synthelabo Compositions pharmaceutiques comprenant de l'amisulpride et leurs applications therapeutiques
FR2762213B1 (fr) * 1997-04-18 1999-05-14 Synthelabo Composition pharmaceutique a retention gastrique
US6169094B1 (en) * 1998-07-14 2001-01-02 Sanofi-Synthelabo Compositions of (S) (-)-amisulpride
CA2450073C (en) 2001-07-25 2017-08-29 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
KR20060011873A (ko) * 2003-05-16 2006-02-03 화이자 프로덕츠 인코포레이티드 비정형 항정신약과 ｇａｂａ 조절제, 항경련성 약물 또는 벤조다이아제핀의 치료 혼합물
FR2857263B1 (fr) * 2003-07-09 2005-09-09 Sanofi Synthelabo Nouvelle composition pharmaceutique solide comprenant de l'amisulpride
EP1753460A2 (en) * 2004-05-11 2007-02-21 Pfizer Products Inc. Combination of atypical antipsychotics and 5-ht1b receptor antagonists
WO2006116221A2 (en) * 2005-04-22 2006-11-02 Wyeth Therapeutic combinations for the treatment or prevention of psychotic disorders
EP2392258B1 (en) 2005-04-28 2014-10-08 Proteus Digital Health, Inc. Pharma-informatics system
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료
US7825156B2 (en) * 2007-02-02 2010-11-02 Copharms Method of treating bipolar depression with a benzamide derivative
CA2727573A1 (en) * 2008-06-25 2009-12-30 Pfizer Inc. Diaryl compounds and uses thereof
US20100105755A1 (en) * 2008-09-12 2010-04-29 Auspex Pharmaceuticals, Inc. Substituted benzamide modulators of dopamine receptor
EP2398500B1 (en) 2009-02-20 2019-03-13 2-BBB Medicines B.V. Glutathione-based drug delivery system
MY163048A (en) 2009-05-06 2017-08-15 Laboratory Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
CN101898991B (zh) * 2009-05-31 2013-09-25 江苏天士力帝益药业有限公司 一种(s)(-)-氨磺必利d-(-)-酒石酸盐的合成方法
CN101628886B (zh) * 2009-08-25 2012-12-12 北京紫萌同达科技有限公司 一种2-甲氧基-4-氨基-5-乙砜基苯甲酸的合成方法
AU2016216578B2 (en) * 2010-03-11 2017-11-23 Acacia Pharma Limited The use of amisulpride as an anti-emetic
GB201004020D0 (en) * 2010-03-11 2010-04-21 Acacia Pharma Ltd New therapeutic use
AU2014202535B2 (en) * 2010-03-11 2016-05-26 Acacia Pharma Limited The use of amisulpride as an anti-emetic
EP2582665A1 (en) 2010-06-17 2013-04-24 Lupin Limited An improved process for preparation of amisulpride
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CN103304453A (zh) * 2013-06-18 2013-09-18 苏州诚和医药化学有限公司 两步法合成2-甲氧基-4-氨基-5-乙砜基苯甲酸
CN103319384A (zh) * 2013-06-18 2013-09-25 苏州诚和医药化学有限公司 制备2-甲氧基-4-氨基-5-乙砜基苯甲酸的方法
CN103450058B (zh) * 2013-09-18 2015-10-14 广安凯特医药化工有限公司 一种氨磺必利酸的制备方法
CN104725292B (zh) * 2015-03-23 2017-07-25 湖北荆江源制药股份有限公司 一种(s)(‑)‑氨磺必利的制备方法
GB201618425D0 (en) * 2016-11-01 2016-12-14 Acacia Pharma Ltd method
US11377421B2 (en) 2016-11-28 2022-07-05 Lb Pharmaceuticals Inc. Psychotropic agents and uses thereof
CN110248655B (zh) 2016-11-28 2023-07-07 Lb制药公司 精神药剂及其用途
CN106995397B (zh) * 2016-12-12 2020-01-14 河北医科大学 R-氨磺必利药用盐、制备方法、晶型及其用途
GB201702250D0 (en) 2017-02-10 2017-03-29 Acacia Pharma Ltd Method
CN112118838A (zh) 2017-12-05 2020-12-22 赛诺维信制药公司 非外消旋混合物及其用途
EP3720435B1 (en) 2017-12-05 2024-03-06 Sunovion Pharmaceuticals Inc. Crystal forms and production methods thereof
CN110790693A (zh) * 2018-08-02 2020-02-14 北京万全德众医药生物技术有限公司 一种(s)(-)-氨磺必利的制备方法
WO2020247627A1 (en) 2019-06-04 2020-12-10 Sunovion Pharmaceuticals Inc. Modified release formulations and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3342826A (en) * 1964-01-13 1967-09-19 Ile De France Heterocyclic aminoalkyl benzamides
FR2313935A1 (fr) * 1975-06-10 1977-01-07 Ile De France Nouveaux benzamides substitues, leurs derives et leur procede de preparation
US3862139A (en) * 1972-06-23 1975-01-21 Delmar Chem Heterocyclic benzamide compounds
FR2244760B1 (da) * 1973-09-25 1980-06-27 Ile De France
FR2299862B1 (fr) * 1975-02-07 1978-07-21 Ile De France Nouveau
FR2294698A1 (fr) * 1974-12-18 1976-07-16 Synthelabo Nouveaux derives des methoxy-2 benzamides substitues, leurs sels, leur preparation et les medicaments qui en renferment
CA1039731A (en) * 1974-12-18 1978-10-03 Synthelabo Process for preparing new 2-methoxy-benzamide derivatives

Also Published As

Publication number Publication date
SE8603773D0 (sv) 1986-09-09
MX7623E (es) 1990-03-27
CH637927A5 (fr) 1983-08-31
NL191707C (nl) 1996-04-02
MX5793E (es) 1984-07-19
YU25483A (en) 1983-10-31
GB2083458B (en) 1983-03-09
BG31496A3 (en) 1982-01-15
IE47798B1 (en) 1984-06-27
IL56411A (en) 1982-09-30
SE448874B (sv) 1987-03-23
GB2012765A (en) 1979-08-01
DK158346C (da) 1990-10-08
AU4337379A (en) 1979-07-26
BG31497A3 (en) 1982-01-15
IT7947706A0 (it) 1979-01-18
NO151320C (no) 1985-04-17
AR220574A1 (es) 1980-11-14
NL7900457A (nl) 1979-07-24
RO76393A (ro) 1981-03-30
PH15725A (en) 1983-03-18
FI790182A (fi) 1979-07-21
YU42172B (en) 1988-06-30
NO790180L (no) 1979-07-23
GB2012765B (en) 1982-09-08
OA06156A (fr) 1981-06-30
DE2901181A1 (de) 1979-07-26
CS226181B2 (en) 1984-03-19
IT1164655B (it) 1987-04-15
AT377977B (de) 1985-05-28
YU5079A (en) 1983-06-30
DD141520A5 (de) 1980-05-07
SE460968B (sv) 1989-12-11
GB2083458A (en) 1982-03-24
US4294828A (en) 1981-10-13
JPS6049192B2 (ja) 1985-10-31
ZA79219B (en) 1980-01-30
FI71126C (fi) 1986-11-24
NL191707B (nl) 1995-12-01
YU41278B (en) 1986-12-31
ATA39879A (de) 1983-12-15
MC1232A1 (fr) 1979-10-26
BE872585A (fr) 1979-06-07
PH22287A (en) 1988-07-22
ES477782A1 (es) 1979-09-16
PT69068A (fr) 1979-02-01
IL56411A0 (en) 1979-03-12
EG14045A (en) 1983-09-30
NZ189378A (en) 1983-03-15
SE7900380L (sv) 1979-07-21
CY1201A (en) 1983-12-31
FR2415099A1 (fr) 1979-08-17
DK158346B (da) 1990-05-07
ZM579A1 (en) 1979-12-21
HK12184A (en) 1984-02-24
CA1101430A (en) 1981-05-19
PL212899A1 (da) 1980-01-14
RO80311A (ro) 1982-12-06
AU528561B2 (en) 1983-05-05
GR64431B (en) 1980-03-21
SU820659A3 (ru) 1981-04-07
LU80786A1 (fr) 1979-09-07
NO151320B (no) 1984-12-10
PL118151B1 (en) 1981-09-30
FI71126B (fi) 1986-08-14
DE2901181C2 (de) 1984-07-19
IN150226B (da) 1982-08-21
ES476755A1 (es) 1979-06-01
SE8603773L (sv) 1986-09-09
IE790092L (en) 1979-07-20
FR2415099B1 (da) 1981-02-20
AR221354A1 (es) 1981-01-30
JPS54145658A (en) 1979-11-14
US4401822A (en) 1983-08-30
PL116532B1 (en) 1981-06-30
HU179793B (en) 1982-12-28

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