DK2059513T3 - Fremgangsmåde til fremstillingen af 1,2,4-oxadiazolbenzoesyrer - Google Patents
Fremgangsmåde til fremstillingen af 1,2,4-oxadiazolbenzoesyrerInfo
- Publication number
- DK2059513T3 DK2059513T3 DK07837899.9T DK07837899T DK2059513T3 DK 2059513 T3 DK2059513 T3 DK 2059513T3 DK 07837899 T DK07837899 T DK 07837899T DK 2059513 T3 DK2059513 T3 DK 2059513T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- benzoic acids
- oxadiazole benzoic
- oxadiazole
- acids
- Prior art date
Links
- SNGNHEIIYFNIIL-UHFFFAOYSA-N benzoic acid;1,2,4-oxadiazole Chemical class C=1N=CON=1.OC(=O)C1=CC=CC=C1 SNGNHEIIYFNIIL-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US84359506P | 2006-09-08 | 2006-09-08 | |
| PCT/US2007/019561 WO2008030570A1 (en) | 2006-09-08 | 2007-09-06 | Processes for the preparation of 1,2,4-oxadiazole benzoic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2059513T3 true DK2059513T3 (da) | 2013-05-06 |
Family
ID=38935880
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK07837899.9T DK2059513T3 (da) | 2006-09-08 | 2007-09-06 | Fremgangsmåde til fremstillingen af 1,2,4-oxadiazolbenzoesyrer |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US7678922B2 (https=) |
| EP (1) | EP2059513B1 (https=) |
| JP (2) | JP5955494B2 (https=) |
| KR (1) | KR101466368B1 (https=) |
| CN (1) | CN101535284B (https=) |
| AR (3) | AR062715A1 (https=) |
| AU (1) | AU2007292915B2 (https=) |
| BR (1) | BRPI0716996B8 (https=) |
| CA (2) | CA2662749C (https=) |
| CL (1) | CL2007002606A1 (https=) |
| DK (1) | DK2059513T3 (https=) |
| ES (1) | ES2404348T3 (https=) |
| IL (1) | IL197445A (https=) |
| MX (1) | MX2009002439A (https=) |
| MY (1) | MY148598A (https=) |
| NZ (2) | NZ575511A (https=) |
| PE (2) | PE20120669A1 (https=) |
| PL (1) | PL2059513T3 (https=) |
| PT (1) | PT2059513E (https=) |
| RU (1) | RU2495030C2 (https=) |
| TW (1) | TWI482761B (https=) |
| UA (1) | UA99265C2 (https=) |
| WO (1) | WO2008030570A1 (https=) |
| ZA (1) | ZA200901782B (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4101846B1 (en) | 2003-04-11 | 2023-08-02 | PTC Therapeutics, Inc. | 1,2,4-oxadiazole benzoic acid compounds and their use for nonsense suppression and the treatment of disease |
| PL2402002T3 (pl) | 2005-04-08 | 2018-11-30 | Ptc Therapeutics, Inc. | Kompozycje zawierające kwas 1,2,4-oksadiazolobenzoesowy i ich zastosowania do leczenia chorób związanych z przedwczesnym kodonem stop |
| EP2387995A1 (en) | 2006-03-30 | 2011-11-23 | PTC Therapeutics, Inc. | Methods for the production of functional protein from DNA having a nonsense mutation and the treatment of disorders associated therewith |
| UA99265C2 (ru) * | 2006-09-08 | 2012-08-10 | ПиТиСи ТЕРАПЬЮТИКС, ИНК. | Способ получения 1,2,4-оксадиазолбензойной кислоты и ее производных (варианты) |
| US8101641B2 (en) | 2006-09-25 | 2012-01-24 | Ptc Therapeutics, Inc. | Hydroxylated 1,2,4-oxadiazole benzoic acid compounds and compositions thereof |
| NZ575795A (en) * | 2006-09-25 | 2012-03-30 | Ptc Therapeutics Inc | Crystalline forms of 3-[5-(2-fluorophenyl)-[1,2,4]oxadiazol-3-yl]-benzoic acid |
| MX2009003909A (es) | 2006-10-12 | 2009-05-25 | Ptc Therapeutics Inc | Métodos para dosificar un compuesto 1,2,4, - oxadiazol oralmente activo para el tratamiento de supresión de la mutación finalizadora. |
| CN101714009A (zh) * | 2009-05-14 | 2010-05-26 | 翁印嵩 | 集成通用电话功能的计算机 |
| ES2610362T3 (es) | 2011-01-25 | 2017-04-27 | Viviabiotech, S.L. | Derivados de 1,2,4-oxadiazol como fármacos moduladores del receptor para el péptido glp-1 |
| EP2867230B1 (en) | 2012-07-02 | 2020-02-12 | Monsanto Technology LLC | Process for the preparation of 3,5-disubstituted-1,2,4-oxadiazoles |
| TWI695717B (zh) | 2014-03-06 | 2020-06-11 | 美商 Ptc 治療公司 | １,２,４-二唑苯甲酸之鹽及醫藥組合物 |
| CN105461650B (zh) * | 2014-09-12 | 2018-04-13 | 杭州普晒医药科技有限公司 | 一种噁二唑化合物的溶剂化物及其制备方法 |
| CN106316885B (zh) * | 2015-07-03 | 2019-02-12 | 普济生物科技（台州）有限公司 | 一种3-[5-(2-氟苯基)-1,2,4-噁二唑-3-基]苯甲酸的制备方法 |
| CN108348527A (zh) | 2015-10-30 | 2018-07-31 | Ptc医疗公司 | 用于治疗癫痫的方法 |
| TW201808922A (zh) | 2016-06-20 | 2018-03-16 | 台灣神隆股份有限公司 | 製備阿塔魯仁及其中間體的方法 |
| WO2020128816A2 (en) | 2018-12-20 | 2020-06-25 | Pfizer Inc. | Pharmaceutical compositions and methods comprising a combination of a benzoxazole transthyretin stabilizer and an additional therapeutic agent |
| EP4473971A3 (en) | 2019-04-10 | 2025-02-19 | PTC Therapeutics, Inc. | Method for treating nonsense mutation mediated duchenne muscular dystrophy in pediatric patients |
| WO2022112919A1 (en) | 2020-11-25 | 2022-06-02 | Pfizer Inc. | (aza)benzothiazolyl substituted pyrazole compounds |
| CN113045510B (zh) * | 2021-03-31 | 2022-05-27 | 北京大学生命科学华东产业研究院 | 一种阿塔鲁伦的制备方法 |
| CN114920667B (zh) * | 2022-06-30 | 2024-06-21 | 湖南大学 | 一种阿塔鲁伦酯的电化学制备方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2801509A1 (de) * | 1978-01-12 | 1979-07-19 | Schering Ag | 1,2,4-oxadiazolderivate, verfahren zur herstellung dieser verbindungen sowie diese enthaltende selektive herbizide mittel |
| DE3905242A1 (de) * | 1989-02-21 | 1990-08-23 | Basf Ag | Verfahren zur herstellung von phenyloxdiazolylanilinen |
| NZ234760A (en) * | 1989-08-18 | 1991-09-25 | Sterling Drug Inc | Antiviral oxazole compounds and compositions |
| DE4425794A1 (de) * | 1994-07-21 | 1996-01-25 | Basf Ag | Nitrofarbstoffe |
| US6660753B2 (en) | 1999-08-19 | 2003-12-09 | Nps Pharmaceuticals, Inc. | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
| KR20040004705A (ko) | 2001-06-08 | 2004-01-13 | 시토비아 인크. | 카스파제의 활성제 및 아폽토시스의 유도제로서의 치환된3-아릴-5-아릴-[1,2,4]-옥사디아졸과 유사체 및 이의 용도 |
| MY151199A (en) | 2001-11-02 | 2014-04-30 | Rigel Pharmaceuticals Inc | Substituted diphenyl heterocycles useful for treating hcv infection |
| MXPA05001592A (es) | 2002-08-09 | 2005-05-05 | Astrazeneca Ab | Oxadiazoles como moduladores de receptor-5 de glutamato metabotropico. |
| GB0303503D0 (en) | 2003-02-14 | 2003-03-19 | Novartis Ag | Organic compounds |
| EP4101846B1 (en) | 2003-04-11 | 2023-08-02 | PTC Therapeutics, Inc. | 1,2,4-oxadiazole benzoic acid compounds and their use for nonsense suppression and the treatment of disease |
| US20050075375A1 (en) | 2003-05-14 | 2005-04-07 | Anadys Pharmaceuticals, Inc. | Heterocyclic compounds for treating hepatitis C virus |
| PL2402002T3 (pl) * | 2005-04-08 | 2018-11-30 | Ptc Therapeutics, Inc. | Kompozycje zawierające kwas 1,2,4-oksadiazolobenzoesowy i ich zastosowania do leczenia chorób związanych z przedwczesnym kodonem stop |
| UA99265C2 (ru) * | 2006-09-08 | 2012-08-10 | ПиТиСи ТЕРАПЬЮТИКС, ИНК. | Способ получения 1,2,4-оксадиазолбензойной кислоты и ее производных (варианты) |
-
2007
- 2007-09-06 UA UAA200903350A patent/UA99265C2/ru unknown
- 2007-09-06 MX MX2009002439A patent/MX2009002439A/es active IP Right Grant
- 2007-09-06 DK DK07837899.9T patent/DK2059513T3/da active
- 2007-09-06 AU AU2007292915A patent/AU2007292915B2/en active Active
- 2007-09-06 NZ NZ575511A patent/NZ575511A/en unknown
- 2007-09-06 CA CA2662749A patent/CA2662749C/en active Active
- 2007-09-06 EP EP07837899A patent/EP2059513B1/en active Active
- 2007-09-06 ZA ZA200901782A patent/ZA200901782B/xx unknown
- 2007-09-06 RU RU2009113019/04A patent/RU2495030C2/ru active
- 2007-09-06 MY MYPI20090941A patent/MY148598A/en unknown
- 2007-09-06 PT PT78378999T patent/PT2059513E/pt unknown
- 2007-09-06 CA CA2842625A patent/CA2842625C/en active Active
- 2007-09-06 US US11/899,813 patent/US7678922B2/en active Active - Reinstated
- 2007-09-06 ES ES07837899T patent/ES2404348T3/es active Active
- 2007-09-06 BR BRPI0716996A patent/BRPI0716996B8/pt active IP Right Grant
- 2007-09-06 NZ NZ598012A patent/NZ598012A/xx unknown
- 2007-09-06 KR KR1020097007202A patent/KR101466368B1/ko not_active Expired - Fee Related
- 2007-09-06 WO PCT/US2007/019561 patent/WO2008030570A1/en not_active Ceased
- 2007-09-06 PL PL07837899T patent/PL2059513T3/pl unknown
- 2007-09-06 JP JP2009527430A patent/JP5955494B2/ja active Active
- 2007-09-06 CN CN200780041169.XA patent/CN101535284B/zh active Active
- 2007-09-07 PE PE2011001405A patent/PE20120669A1/es active IP Right Grant
- 2007-09-07 PE PE2007001203A patent/PE20080771A1/es active IP Right Grant
- 2007-09-07 TW TW096133607A patent/TWI482761B/zh active
- 2007-09-07 CL CL200702606A patent/CL2007002606A1/es unknown
- 2007-09-07 AR ARP070103975A patent/AR062715A1/es not_active Application Discontinuation
-
2009
- 2009-03-05 IL IL197445A patent/IL197445A/en active IP Right Grant
- 2009-11-13 US US12/617,757 patent/US8367841B2/en active Active
-
2014
- 2014-05-20 JP JP2014103966A patent/JP2014193896A/ja active Pending
-
2017
- 2017-01-27 AR ARP170100223A patent/AR107474A2/es not_active Application Discontinuation
-
2020
- 2020-05-12 AR ARP200101362A patent/AR118922A2/es unknown
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