DK1763586T3 - Ny sekvens til forbedring af ekspressionen af nukleinsyre - Google Patents

Ny sekvens til forbedring af ekspressionen af nukleinsyre

Info

Publication number
DK1763586T3
DK1763586T3 DK05756870T DK05756870T DK1763586T3 DK 1763586 T3 DK1763586 T3 DK 1763586T3 DK 05756870 T DK05756870 T DK 05756870T DK 05756870 T DK05756870 T DK 05756870T DK 1763586 T3 DK1763586 T3 DK 1763586T3
Authority
DK
Denmark
Prior art keywords
expression
nucleic acid
enhance
new sequence
repressor
Prior art date
Application number
DK05756870T
Other languages
Danish (da)
English (en)
Inventor
Arie Pieter Otte
Theodorus Hendrikus Jaco Kwaks
Richard George Antonius Sewalt
Blokland Henricus Johannes Van
Original Assignee
Chromagenics Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34971366&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1763586(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chromagenics Bv filed Critical Chromagenics Bv
Application granted granted Critical
Publication of DK1763586T3 publication Critical patent/DK1763586T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK05756870T 2004-07-08 2005-07-07 Ny sekvens til forbedring af ekspressionen af nukleinsyre DK1763586T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58700704P 2004-07-08 2004-07-08
EP2004051405 2004-07-08
PCT/EP2005/053251 WO2006005718A2 (en) 2004-07-08 2005-07-07 Novel sequence for improving expression of nucleic acid

Publications (1)

Publication Number Publication Date
DK1763586T3 true DK1763586T3 (da) 2008-03-17

Family

ID=34971366

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05756870T DK1763586T3 (da) 2004-07-08 2005-07-07 Ny sekvens til forbedring af ekspressionen af nukleinsyre

Country Status (20)

Country Link
US (1) US7825232B2 (xx)
JP (1) JP4805262B2 (xx)
KR (1) KR101188013B1 (xx)
CN (1) CN1981057B (xx)
AT (1) ATE378426T1 (xx)
AU (1) AU2005261699B2 (xx)
BR (1) BRPI0512798A (xx)
CA (1) CA2573022C (xx)
DE (1) DE602005003369T2 (xx)
DK (1) DK1763586T3 (xx)
EA (1) EA011747B1 (xx)
ES (1) ES2296201T3 (xx)
HK (1) HK1097004A1 (xx)
IL (1) IL180531A (xx)
MX (1) MXPA06014553A (xx)
NO (1) NO341862B1 (xx)
NZ (1) NZ551510A (xx)
PT (1) PT1763586E (xx)
WO (1) WO2006005718A2 (xx)
ZA (1) ZA200610470B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1572994T3 (da) 2002-12-20 2007-05-29 Chromagenics Bv Midler og fremgangsmåder til fremstilling af en protein gennem chromatinåbnere, som kan göre chromatin mere tilgængeligt for transkriptionsfaktorer
US8999667B2 (en) 2004-11-08 2015-04-07 Chromagenics B.V. Selection of host cells expressing protein at high levels
US20100136616A1 (en) * 2004-11-08 2010-06-03 Chromagenics B.V. Selection of Host Cells Expressing Protein at High Levels
US20060195935A1 (en) 2004-11-08 2006-08-31 Chromagenics B.V. Selection of host cells expressing protein at high levels
US8039230B2 (en) 2004-11-08 2011-10-18 Chromagenics B.V. Selection of host cells expressing protein at high levels
JP5291341B2 (ja) * 2004-11-08 2013-09-18 クロマジェニックス ベー ヴェー タンパク質を高レベルで発現する宿主細胞の選定
ES2384391T3 (es) * 2004-11-08 2012-07-04 Chromagenics B.V. Selección de células hospedantes que expresan proteína a altos niveles
DK2443239T3 (en) 2009-06-15 2016-02-15 Cellagenics B V New stringent selection markers
US9790517B2 (en) 2010-06-15 2017-10-17 Cellagenics B.V. Intergenic elements for enhancing gene expression
EP2611915B1 (en) 2010-09-01 2015-04-15 Cellagenics B.V. Nucleic acid fragments from a ribosomal protein promoter for enhancing gene expression
CN110484563B (zh) * 2019-07-25 2023-04-07 新乡医学院 哺乳动物细胞组合表达载体、表达系统、制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60236333D1 (de) 2001-07-04 2010-06-17 Chromagenics Bv DNS-Sequenzen mit anti-repressor Aktivität
NZ537073A (en) * 2002-06-14 2006-08-31 Chromagenics B A method for simultaneous production of multiple proteins; vectors and cells for use therein
DK1572994T3 (da) * 2002-12-20 2007-05-29 Chromagenics Bv Midler og fremgangsmåder til fremstilling af en protein gennem chromatinåbnere, som kan göre chromatin mere tilgængeligt for transkriptionsfaktorer

Also Published As

Publication number Publication date
ES2296201T3 (es) 2008-04-16
CN1981057B (zh) 2012-07-04
ZA200610470B (en) 2008-09-25
CA2573022C (en) 2012-03-06
IL180531A0 (en) 2007-06-03
NO341862B1 (no) 2018-02-12
KR101188013B1 (ko) 2012-10-08
IL180531A (en) 2011-04-28
WO2006005718A2 (en) 2006-01-19
JP2008505626A (ja) 2008-02-28
EA011747B1 (ru) 2009-06-30
AU2005261699A1 (en) 2006-01-19
EA200700233A1 (ru) 2007-06-29
NZ551510A (en) 2009-10-30
DE602005003369T2 (de) 2009-03-05
WO2006005718A3 (en) 2006-08-17
JP4805262B2 (ja) 2011-11-02
US7825232B2 (en) 2010-11-02
HK1097004A1 (en) 2007-06-15
CA2573022A1 (en) 2006-01-19
MXPA06014553A (es) 2007-03-12
BRPI0512798A (pt) 2008-04-08
AU2005261699B2 (en) 2009-07-23
KR20070042122A (ko) 2007-04-20
US20070212755A1 (en) 2007-09-13
ATE378426T1 (de) 2007-11-15
DE602005003369D1 (de) 2007-12-27
CN1981057A (zh) 2007-06-13
PT1763586E (pt) 2008-02-25
NO20070757L (no) 2007-02-08

Similar Documents

Publication Publication Date Title
DK1763586T3 (da) Ny sekvens til forbedring af ekspressionen af nukleinsyre
DK1831362T3 (da) Syreaktive svampeproteaser
DK1836299T4 (da) Polypeptider, der har cellobiohydrolaseaktivitet, og polynukleotider, der koder for disse
DK2213724T3 (da) Medium frit for dyreprotein til dyrkning af celler
DK1928901T3 (da) Polypeptider, der har beta-glucosidaseaktivitet og polynukleotider, der koder for samme
DK2287288T3 (da) Medium frit for animalsk protein til dyrkning af celler
HK1210627A1 (en) Preparing crude biological estracts using protease, suitable for preparing cdna cdna
ATE512228T1 (de) Induzierbare expressionssysteme
ATE515488T1 (de) Click-chemie zur herstellung von reportermolekülen
WO2006039541A3 (en) Polypeptides having lipase activity and polynucleotides encoding same
DK1819427T3 (da) Forstærkede kapillarmembraner samt fremgangsmåde til deres fremstilling
CR9969A (es) Anticuerpos anti-globulomero ab, porciones de union a antigeno de estos, hibridomas correspondientes, acidos nucleicos, vectores, celulas huesped, metodos para producir dichos anticuerpos, composiciones que comprenden dichos anticuerpos
EA201070764A1 (ru) Полипептиды, обладающие активностью, усиливающей лизис целлюлозы, и кодирующие их полинуклеотиды
WO2006047469A8 (en) Polypeptides having lipase activity and polynucleotides encoding same
IS8035A (is) Nýir ljósóstöðugir verndarhópar til bættra aðferða við að framleiða fákirnafylkingar
DK1733039T3 (da) Forbedret bakteriel værtscelle til direkte ekspression af peptider
ATE488591T1 (de) Neuer l-lysin-induzierbarer promotor
DK1877551T4 (da) Polypeptider, der har endoglucanaseaktivitet, og polynukleotider, der koder for samme
DK1851320T3 (da) Vacciner på basis af anvendelsen af MVA
NO20081470L (no) Polypeptider som har antimikrobeaktivitet og polynukleotider som koder for disse.
DK1756273T3 (da) Signalpeptid til frembringelse af et polypeptid
ATE486127T1 (de) Wiederherstellung der aktivität von 5- enolpyruvylshikimat-3-phosphat-synthase durch fragmentkomplementierung
DK1963514T3 (da) Fremgangsmåder til fototransferering af nukleinsyre til levende celler
WO2010038145A3 (en) Kit for the optimisation of protein synthesis/secretion
IS8646A (is) Aðferð til að framleiða spendýrafrumur