NO20070757L - Ny sekvens for forbedring av ekspresjon av nukleinsyre(r) - Google Patents

Ny sekvens for forbedring av ekspresjon av nukleinsyre(r)

Info

Publication number
NO20070757L
NO20070757L NO20070757A NO20070757A NO20070757L NO 20070757 L NO20070757 L NO 20070757L NO 20070757 A NO20070757 A NO 20070757A NO 20070757 A NO20070757 A NO 20070757A NO 20070757 L NO20070757 L NO 20070757L
Authority
NO
Norway
Prior art keywords
nucleic acid
new sequence
enhancing expression
expression
repressor
Prior art date
Application number
NO20070757A
Other languages
English (en)
Other versions
NO341862B1 (no
Inventor
Arie Pieter Otte
Theodorus Hendrikus Jaco Kwaks
Richard George Antonius Sewalt
Henricus Johannes Mar Blokland
Original Assignee
Chromagenics Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34971366&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20070757(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chromagenics Bv filed Critical Chromagenics Bv
Publication of NO20070757L publication Critical patent/NO20070757L/no
Publication of NO341862B1 publication Critical patent/NO341862B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Oppfinnelsen skaffer til veie et nytt anti-repressorelement, som er anvendelig for å forbedre ekspresjonen av nukleinsyrer i en vertscelle. Metoder som anvender det nye anti-repressorelementet for å produsere et protein av interesse er også fremskaffet. Oppfinnelsen skaffer også til veie nye konfigurasjoner av ekspresjons-kassetter som består av anti-repressorelementer.
NO20070757A 2004-07-08 2007-02-08 Ny sekvens for forbedring av ekspresjon av nukleinsyre(r) NO341862B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58700704P 2004-07-08 2004-07-08
EP2004051405 2004-07-08
PCT/EP2005/053251 WO2006005718A2 (en) 2004-07-08 2005-07-07 Novel sequence for improving expression of nucleic acid

Publications (2)

Publication Number Publication Date
NO20070757L true NO20070757L (no) 2007-02-08
NO341862B1 NO341862B1 (no) 2018-02-12

Family

ID=34971366

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20070757A NO341862B1 (no) 2004-07-08 2007-02-08 Ny sekvens for forbedring av ekspresjon av nukleinsyre(r)

Country Status (20)

Country Link
US (1) US7825232B2 (no)
JP (1) JP4805262B2 (no)
KR (1) KR101188013B1 (no)
CN (1) CN1981057B (no)
AT (1) ATE378426T1 (no)
AU (1) AU2005261699B2 (no)
BR (1) BRPI0512798A (no)
CA (1) CA2573022C (no)
DE (1) DE602005003369T2 (no)
DK (1) DK1763586T3 (no)
EA (1) EA011747B1 (no)
ES (1) ES2296201T3 (no)
HK (1) HK1097004A1 (no)
IL (1) IL180531A (no)
MX (1) MXPA06014553A (no)
NO (1) NO341862B1 (no)
NZ (1) NZ551510A (no)
PT (1) PT1763586E (no)
WO (1) WO2006005718A2 (no)
ZA (1) ZA200610470B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1572994B1 (en) * 2002-12-20 2007-02-21 Chromagenics B.V. Means and methods for producing a protein through chromatin openers that are capable of rendering chromatin more accessible to transcription factors
EA010863B1 (ru) * 2004-11-08 2008-12-30 Хромагеникс Б.В. Отбор клеток-хозяев, экспрессирующих белок на высоких уровнях
DK1809750T3 (da) 2004-11-08 2012-06-25 Chromagenics Bv Selektion af værtsceller, der udtrykker protein ved høje niveauer
US8999667B2 (en) * 2004-11-08 2015-04-07 Chromagenics B.V. Selection of host cells expressing protein at high levels
US20060195935A1 (en) 2004-11-08 2006-08-31 Chromagenics B.V. Selection of host cells expressing protein at high levels
US20100136616A1 (en) * 2004-11-08 2010-06-03 Chromagenics B.V. Selection of Host Cells Expressing Protein at High Levels
US8039230B2 (en) 2004-11-08 2011-10-18 Chromagenics B.V. Selection of host cells expressing protein at high levels
EP2443239B1 (en) * 2009-06-15 2015-11-25 Cellagenics B.V. Novel stringent selectable markers
EP2582816B1 (en) 2010-06-15 2017-12-20 Cellagenics B.V. Novel intergenic elements for enhancing gene expression
US9650630B2 (en) 2010-09-01 2017-05-16 Cellagenics B.V. Nucleic acid fragments from a ribosomal protein promoter for enhancing gene expression
CN110484563B (zh) * 2019-07-25 2023-04-07 新乡医学院 哺乳动物细胞组合表达载体、表达系统、制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60236334D1 (de) 2001-07-04 2010-06-17 Chromagenics Bv DNS-Sequenzen mit anti-repressor Aktivität
WO2003106684A2 (en) * 2002-06-14 2003-12-24 Chromagenics B.V. A method for simultaneous production of multiple proteins; vectors and cells for use therein
EP1572994B1 (en) * 2002-12-20 2007-02-21 Chromagenics B.V. Means and methods for producing a protein through chromatin openers that are capable of rendering chromatin more accessible to transcription factors

Also Published As

Publication number Publication date
EA011747B1 (ru) 2009-06-30
JP2008505626A (ja) 2008-02-28
CN1981057A (zh) 2007-06-13
DE602005003369T2 (de) 2009-03-05
KR20070042122A (ko) 2007-04-20
IL180531A0 (en) 2007-06-03
CA2573022C (en) 2012-03-06
US7825232B2 (en) 2010-11-02
DE602005003369D1 (de) 2007-12-27
NZ551510A (en) 2009-10-30
IL180531A (en) 2011-04-28
ZA200610470B (en) 2008-09-25
DK1763586T3 (da) 2008-03-17
JP4805262B2 (ja) 2011-11-02
AU2005261699B2 (en) 2009-07-23
MXPA06014553A (es) 2007-03-12
WO2006005718A3 (en) 2006-08-17
PT1763586E (pt) 2008-02-25
BRPI0512798A (pt) 2008-04-08
CN1981057B (zh) 2012-07-04
WO2006005718A2 (en) 2006-01-19
AU2005261699A1 (en) 2006-01-19
EA200700233A1 (ru) 2007-06-29
HK1097004A1 (en) 2007-06-15
ES2296201T3 (es) 2008-04-16
ATE378426T1 (de) 2007-11-15
NO341862B1 (no) 2018-02-12
CA2573022A1 (en) 2006-01-19
US20070212755A1 (en) 2007-09-13
KR101188013B1 (ko) 2012-10-08

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