ATE445009T1 - Signalpeptid zur herstellung eines polypeptids - Google Patents

Signalpeptid zur herstellung eines polypeptids

Info

Publication number
ATE445009T1
ATE445009T1 AT05748651T AT05748651T ATE445009T1 AT E445009 T1 ATE445009 T1 AT E445009T1 AT 05748651 T AT05748651 T AT 05748651T AT 05748651 T AT05748651 T AT 05748651T AT E445009 T1 ATE445009 T1 AT E445009T1
Authority
AT
Austria
Prior art keywords
polypeptide
signal peptide
producing
nucleotide sequence
nucleic acid
Prior art date
Application number
AT05748651T
Other languages
English (en)
Inventor
Tomoko Matsui
Henriette Draborg
Steffen Danielsen
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes As filed Critical Novozymes As
Application granted granted Critical
Publication of ATE445009T1 publication Critical patent/ATE445009T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT05748651T 2004-06-14 2005-06-14 Signalpeptid zur herstellung eines polypeptids ATE445009T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200400917 2004-06-14
PCT/DK2005/000387 WO2005121333A1 (en) 2004-06-14 2005-06-14 Signal peptide for producing a polypeptide

Publications (1)

Publication Number Publication Date
ATE445009T1 true ATE445009T1 (de) 2009-10-15

Family

ID=34956242

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05748651T ATE445009T1 (de) 2004-06-14 2005-06-14 Signalpeptid zur herstellung eines polypeptids

Country Status (7)

Country Link
EP (1) EP1756273B1 (de)
JP (1) JP4809347B2 (de)
CN (1) CN1969041B (de)
AT (1) ATE445009T1 (de)
DE (1) DE602005017034D1 (de)
DK (1) DK1756273T3 (de)
WO (1) WO2005121333A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2319489B1 (es) * 2007-07-11 2010-02-10 Universidade Da Coruña Cepas de levadura capaces de secretar beta-galactosidasa al medio y su uso para la produccion de biomasa, etanol, beta-galactosidasa y proteinas de interes.
CN103483423B (zh) * 2010-09-17 2015-04-29 上海凯茂生物医药有限公司 一种人工合成的信号肽及其应用
CN103797114A (zh) 2011-02-23 2014-05-14 杜邦营养生物科学有限公司 生产能够水解叶绿素或叶绿素衍生物的重组酶的方法
WO2012127001A1 (en) * 2011-03-23 2012-09-27 Novozymes A/S Methods for producing secreted polypeptides
EP2794873A1 (de) * 2011-11-08 2014-10-29 Novozymes A/S Verfahren zur herstellung von archeae-protease in hefe
CN122012456A (zh) * 2013-12-11 2026-05-12 诺维信公司 角质酶变体以及对其进行编码的多核苷酸
CN105802989B (zh) * 2014-12-31 2020-05-19 江苏众红生物工程创药研究院有限公司 毕赤酵母表达重组蛋白的载体、基因、方法及应用
CN112205512A (zh) * 2019-07-11 2021-01-12 江南大学 一种低致敏性植物蛋白肉的制备方法
WO2025133003A2 (en) 2023-12-19 2025-06-26 21St.Bio A/S Non-animal bovine beta lactoglobulin

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
CA2191718A1 (en) 1994-06-03 1995-12-14 Randy M. Berka Phosphonyldipeptides useful in the treatment of cardiovascular diseases
ATE294871T1 (de) 1994-06-30 2005-05-15 Novozymes Biotech Inc Nicht-toxisches, nicht-toxigenes, nicht- pathogenes fusarium expressionssystem und darin zu verwendende promotoren und terminatoren
CA2203398A1 (en) * 1994-10-26 1996-05-09 Thomas Sandal An enzyme with lipolytic activity
ZA9610456B (en) * 1995-12-20 1997-06-20 Novo Nordisk As N-terminally extended proteins expressed in yeast
AU1750697A (en) 1996-01-19 1997-08-11 Novo Nordisk Biotech, Inc. Morphological mutants of filamentous fungi
US6292282B1 (en) 1998-08-10 2001-09-18 Templex Technology, Inc. Time-wavelength multiple access optical communication systems and methods
JP5043254B2 (ja) 1998-10-26 2012-10-10 ノボザイムス アクティーゼルスカブ 糸状面細胞内の問題のｄｎａライブラリーの作製及びスクリーニング
NZ523912A (en) * 2000-07-31 2005-03-24 Biolex Inc Expression of biologically active polypeptides in duckweed
JP4362651B2 (ja) * 2001-03-30 2009-11-11 味の素株式会社 タンパク質の分泌生産法
GB0116460D0 (en) * 2001-07-05 2001-08-29 Celltech R&D Ltd Biological products

Also Published As

Publication number Publication date
CN1969041A (zh) 2007-05-23
DE602005017034D1 (de) 2009-11-19
CN1969041B (zh) 2012-06-20
JP2008502354A (ja) 2008-01-31
DK1756273T3 (da) 2010-02-01
EP1756273B1 (de) 2009-10-07
JP4809347B2 (ja) 2011-11-09
WO2005121333A1 (en) 2005-12-22
EP1756273A1 (de) 2007-02-28

Similar Documents

Publication Publication Date Title
WO2008049837A3 (en) Improved alpha factor signal peptide for producing a polypeptide
ATE512980T1 (de) Polypeptide mit beta-glucosidase-aktivität sowie diese codierende polynukleotide
ATE492633T1 (de) Polypeptide mit cellobiohydrolaseaktivität und dafür kodierende polynukleotide
EP2395091A3 (de) Pflanzen mit verbesserten Ertragseigenschaften und Verfahren zu deren Herstellung
WO2005074656A3 (en) Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
EA201071323A1 (ru) Axmi-115, axmi-113, axmi-005, axmi-163, axmi-184 инсектицидные белки и способы их применения
ATE460477T1 (de) Verfahren zur herstellung von d-psicose durch d- psicose-epimerase
DK1622921T3 (da) Varianter af beta-glucosidaser
EP2295555A3 (de) Polypeptide mit Lipase-Aktivität und diese kodierende Polynukleotide
WO2003000941A3 (en) Polypeptides having cellobiohydrolase i activity and polynucleotides encoding same
WO2005001064A3 (en) Polypeptides having alpha-amylase activity and polypeptides encoding same
EP2615174A3 (de) Pflanzen mit verbesserten Ertragseigenschaften und/oder erhöhter abiotischer Stressresistenz sowie Verfahren zu ihrer Herstellung
ATE530643T1 (de) Säureaktive fungale protease
ATE513907T1 (de) Polypeptide mit endoglucanase-aktivität und polynukleotide zu ihrer kodierung
EA200901110A1 (ru) Рекомбинантная клетка-хозяин для получения соединения, представляющего интерес
ATE489377T1 (de) Verfahren zur herstellung von 3-methylamino-1- (thien-2-yl)-propan-1-ol
DE602004028724D1 (de) Verfahren zur herstellung sezernierter polypeptide
WO2006047469A3 (en) Polypeptides having lipase activity and polynucleotides encoding same
WO2007141189A3 (en) Plants having improved growth characteristics and method for making the same
PH12012502520A1 (en) Plants having enhanced yield-related traits and method for making the same
ATE542913T1 (de) Promotorvarianten zur expression von genen in einer pilzzelle
ATE493497T1 (de) Verfahren zur herstellung von oligopeptiden
DE602005017034D1 (de) Signalpeptid zur herstellung eines polypeptids
WO2006053021A3 (en) Methods for engineering polypeptide variants via somatic hypermutation and polypeptides made thereby
DK1157100T3 (da) Oxaloacetathydrolase-defekte svampeværtsceller

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties