DK175769B1 - DNA-sekvens i renset og isoleret form, der koder for enzymet penicillinacetyltransferase, protein, der koder for DNA-sekvensen, vektor, ........... - Google Patents

DNA-sekvens i renset og isoleret form, der koder for enzymet penicillinacetyltransferase, protein, der koder for DNA-sekvensen, vektor, ........... Download PDF

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Publication number
DK175769B1
DK175769B1 DK198906221A DK622189A DK175769B1 DK 175769 B1 DK175769 B1 DK 175769B1 DK 198906221 A DK198906221 A DK 198906221A DK 622189 A DK622189 A DK 622189A DK 175769 B1 DK175769 B1 DK 175769B1
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DK
Denmark
Prior art keywords
pat
sequence
enzyme
dna
penicillin
Prior art date
Application number
DK198906221A
Other languages
Danish (da)
English (en)
Other versions
DK622189D0 (da
DK622189A (da
Inventor
Franz Knauseder
Ernst Leitner
Norbert Palma
Gerhard Weber
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AT92288A external-priority patent/AT390268B/de
Priority claimed from AT180688A external-priority patent/AT391141B/de
Priority claimed from AT220188A external-priority patent/AT391142B/de
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of DK622189D0 publication Critical patent/DK622189D0/da
Publication of DK622189A publication Critical patent/DK622189A/da
Application granted granted Critical
Publication of DK175769B1 publication Critical patent/DK175769B1/da

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C12N9/84—Penicillin amidase (3.5.1.11)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Mold Materials And Core Materials (AREA)
  • Luminescent Compositions (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
DK198906221A 1988-04-08 1989-12-08 DNA-sekvens i renset og isoleret form, der koder for enzymet penicillinacetyltransferase, protein, der koder for DNA-sekvensen, vektor, ........... DK175769B1 (da)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
AT92288 1988-04-08
AT92288A AT390268B (de) 1988-04-08 1988-04-08 Dna aus peniciliium chrysogenum sowie protein, fuer welches diese dna codiert
AT180688 1988-07-13
AT180688A AT391141B (de) 1988-07-13 1988-07-13 Dna, die fuer das enzym penicillinacyltransferase (pat) codiert
AT220188 1988-09-08
AT220188A AT391142B (de) 1988-09-08 1988-09-08 Dna aus penicillium chrysogenum
PCT/EP1989/000374 WO1989009821A1 (en) 1988-04-08 1989-04-07 GENE AND GENE PRODUCT FOR PREPARING beta-LACTAM COMPOUNDS
EP8900374 1989-04-07

Publications (3)

Publication Number Publication Date
DK622189D0 DK622189D0 (da) 1989-12-08
DK622189A DK622189A (da) 1990-02-02
DK175769B1 true DK175769B1 (da) 2005-02-14

Family

ID=27146880

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198906221A DK175769B1 (da) 1988-04-08 1989-12-08 DNA-sekvens i renset og isoleret form, der koder for enzymet penicillinacetyltransferase, protein, der koder for DNA-sekvensen, vektor, ...........

Country Status (12)

Country Link
EP (1) EP0336446B1 (es)
JP (1) JPH0767387B2 (es)
KR (1) KR900700610A (es)
AT (1) ATE105860T1 (es)
AU (1) AU637317B2 (es)
DE (1) DE58907667D1 (es)
DK (1) DK175769B1 (es)
ES (1) ES2054916T3 (es)
FI (1) FI103053B (es)
HK (1) HK99996A (es)
HU (1) HU208845B (es)
WO (1) WO1989009821A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5747285A (en) * 1989-02-01 1998-05-05 Gist-Brocades, Nv. DNA comprising regulatory regions from gene y of penicillium chrysogenum
IL95766A (en) * 1989-09-27 1996-12-05 Lilly Co Eli Recombinant DNA expression vectors And DNA compounds. Which encode Aspergillus acyltransferase activity
US5882879A (en) * 1990-02-28 1999-03-16 Gist-Brocades, N.V. Method for influencing β-lactam antibiotic production and for isolation of large quantities of ACV synthetase
EP0453047B1 (en) * 1990-04-18 1995-07-05 Gist-Brocades N.V. Penicillin G acylase, a gene encoding the same and a method for the production of this enzyme
WO1998002567A2 (en) * 1996-07-16 1998-01-22 Gist-Brocades B.V. PROCESS FOR THE PREPARATION OF CEPHALOSPORINS USING $i(ACREMONIUM CHRYSOGENUM)
EP1851309A2 (en) * 2005-02-24 2007-11-07 DSMIP Assets B.V. Altered isopenicillin-n acyltransferase polypeptides and related polynucleotides

Also Published As

Publication number Publication date
FI895846A0 (fi) 1989-12-07
WO1989009821A1 (en) 1989-10-19
HK99996A (en) 1996-06-14
FI103053B1 (fi) 1999-04-15
EP0336446B1 (de) 1994-05-18
JPH02503750A (ja) 1990-11-08
AU3362689A (en) 1989-11-03
DK622189D0 (da) 1989-12-08
JPH0767387B2 (ja) 1995-07-26
FI103053B (fi) 1999-04-15
HU892092D0 (en) 1990-02-28
HU208845B (en) 1994-01-28
DE58907667D1 (de) 1994-06-23
KR900700610A (ko) 1990-08-16
HUT52156A (en) 1990-06-28
EP0336446A1 (de) 1989-10-11
ATE105860T1 (de) 1994-06-15
AU637317B2 (en) 1993-05-27
DK622189A (da) 1990-02-02
ES2054916T3 (es) 1994-08-16

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Legal Events

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AHB Application shelved due to non-payment
AHB Application shelved due to non-payment
PUP Patent expired