ES2054916T3 - Gen y producto de gen para la obtencion de compuestos de beta-lactama. - Google Patents

Gen y producto de gen para la obtencion de compuestos de beta-lactama.

Info

Publication number
ES2054916T3
ES2054916T3 ES89106214T ES89106214T ES2054916T3 ES 2054916 T3 ES2054916 T3 ES 2054916T3 ES 89106214 T ES89106214 T ES 89106214T ES 89106214 T ES89106214 T ES 89106214T ES 2054916 T3 ES2054916 T3 ES 2054916T3
Authority
ES
Spain
Prior art keywords
gen
lactama
beta
compounds
obtaining
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89106214T
Other languages
English (en)
Inventor
Franz Knauseder
Ernst Leitner
Norbert Palma
Gerhard Weber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz GmbH
Original Assignee
Biochemie GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AT92288A external-priority patent/AT390268B/de
Priority claimed from AT180688A external-priority patent/AT391141B/de
Priority claimed from AT220188A external-priority patent/AT391142B/de
Application filed by Biochemie GmbH filed Critical Biochemie GmbH
Application granted granted Critical
Publication of ES2054916T3 publication Critical patent/ES2054916T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C12N9/80—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5) acting on amide bonds in linear amides (3.5.1)
    • C12N9/84—Penicillin amidase (3.5.1.11)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Mold Materials And Core Materials (AREA)
  • Luminescent Compositions (AREA)
  • Macromonomer-Based Addition Polymer (AREA)

Abstract

LA INVENCION TRATA DE GENES Y PRODUCTOS DE GENES DE UN NUEVO ENZIMA CLAVE EN SU ESTRUCTURA Y FUNCIONALIDAD MULTIVALENTE, EL CUAL CATALIZA LA ULTIMA ETAPA DE LA BIOSINTESIS DE PENICILINA G Y PENICILINA V.
ES89106214T 1988-04-08 1989-04-07 Gen y producto de gen para la obtencion de compuestos de beta-lactama. Expired - Lifetime ES2054916T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AT92288A AT390268B (de) 1988-04-08 1988-04-08 Dna aus peniciliium chrysogenum sowie protein, fuer welches diese dna codiert
AT180688A AT391141B (de) 1988-07-13 1988-07-13 Dna, die fuer das enzym penicillinacyltransferase (pat) codiert
AT220188A AT391142B (de) 1988-09-08 1988-09-08 Dna aus penicillium chrysogenum

Publications (1)

Publication Number Publication Date
ES2054916T3 true ES2054916T3 (es) 1994-08-16

Family

ID=27146880

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89106214T Expired - Lifetime ES2054916T3 (es) 1988-04-08 1989-04-07 Gen y producto de gen para la obtencion de compuestos de beta-lactama.

Country Status (12)

Country Link
EP (1) EP0336446B1 (es)
JP (1) JPH0767387B2 (es)
KR (1) KR900700610A (es)
AT (1) ATE105860T1 (es)
AU (1) AU637317B2 (es)
DE (1) DE58907667D1 (es)
DK (1) DK175769B1 (es)
ES (1) ES2054916T3 (es)
FI (1) FI103053B (es)
HK (1) HK99996A (es)
HU (1) HU208845B (es)
WO (1) WO1989009821A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5747285A (en) * 1989-02-01 1998-05-05 Gist-Brocades, Nv. DNA comprising regulatory regions from gene y of penicillium chrysogenum
IL95766A (en) * 1989-09-27 1996-12-05 Lilly Co Eli Recombinant DNA expression vectors And DNA compounds. Which encode Aspergillus acyltransferase activity
US5882879A (en) * 1990-02-28 1999-03-16 Gist-Brocades, N.V. Method for influencing β-lactam antibiotic production and for isolation of large quantities of ACV synthetase
EP0453047B1 (en) * 1990-04-18 1995-07-05 Gist-Brocades N.V. Penicillin G acylase, a gene encoding the same and a method for the production of this enzyme
WO1998002567A2 (en) * 1996-07-16 1998-01-22 Gist-Brocades B.V. PROCESS FOR THE PREPARATION OF CEPHALOSPORINS USING $i(ACREMONIUM CHRYSOGENUM)
EP1851309A2 (en) * 2005-02-24 2007-11-07 DSMIP Assets B.V. Altered isopenicillin-n acyltransferase polypeptides and related polynucleotides

Also Published As

Publication number Publication date
FI895846A0 (fi) 1989-12-07
WO1989009821A1 (en) 1989-10-19
HK99996A (en) 1996-06-14
FI103053B1 (fi) 1999-04-15
EP0336446B1 (de) 1994-05-18
JPH02503750A (ja) 1990-11-08
AU3362689A (en) 1989-11-03
DK622189D0 (da) 1989-12-08
JPH0767387B2 (ja) 1995-07-26
FI103053B (fi) 1999-04-15
HU892092D0 (en) 1990-02-28
HU208845B (en) 1994-01-28
DE58907667D1 (de) 1994-06-23
DK175769B1 (da) 2005-02-14
KR900700610A (ko) 1990-08-16
HUT52156A (en) 1990-06-28
EP0336446A1 (de) 1989-10-11
ATE105860T1 (de) 1994-06-15
AU637317B2 (en) 1993-05-27
DK622189A (da) 1990-02-02

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