ES2090031T3 - Proceso para la preparacion enzimatica de beta-lactamas. - Google Patents

Proceso para la preparacion enzimatica de beta-lactamas.

Info

Publication number
ES2090031T3
ES2090031T3 ES89201074T ES89201074T ES2090031T3 ES 2090031 T3 ES2090031 T3 ES 2090031T3 ES 89201074 T ES89201074 T ES 89201074T ES 89201074 T ES89201074 T ES 89201074T ES 2090031 T3 ES2090031 T3 ES 2090031T3
Authority
ES
Spain
Prior art keywords
beta
lactamas
enzymatic preparation
enzymatic
aminophenylacetamido
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89201074T
Other languages
English (en)
Inventor
Der Laken Cornelis Jacobus Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gist Brocades NV
Original Assignee
Gist Brocades NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades NV filed Critical Gist Brocades NV
Application granted granted Critical
Publication of ES2090031T3 publication Critical patent/ES2090031T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P37/00—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin
    • C12P37/04—Preparation of compounds having a 4-thia-1-azabicyclo [3.2.0] heptane ring system, e.g. penicillin by acylation of the substituent in the 6 position

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

SE PREPARAN BETA - LACTAMAS QUE TIENEN UNA CADENA LATERAL 6 - D ALFA - AMINOFENILACETAMIDA EN GRAN CANTIDAD POR REACCION ENZIMATICA DE 6 - AMINO BETA - LACTAMA CON UN DERIVADO DE D,L - FENILGLICINA, PREFERENTEMENTE A TEMPERATURAS ENTRE 0 Y 25 (GRADOS) C.
ES89201074T 1988-04-26 1989-04-25 Proceso para la preparacion enzimatica de beta-lactamas. Expired - Lifetime ES2090031T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP88200811 1988-04-26

Publications (1)

Publication Number Publication Date
ES2090031T3 true ES2090031T3 (es) 1996-10-16

Family

ID=8199787

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89201074T Expired - Lifetime ES2090031T3 (es) 1988-04-26 1989-04-25 Proceso para la preparacion enzimatica de beta-lactamas.

Country Status (9)

Country Link
EP (1) EP0339751B1 (es)
JP (1) JP2771244B2 (es)
KR (1) KR890016184A (es)
AT (1) ATE138690T1 (es)
DE (1) DE68926548T2 (es)
DK (1) DK198789A (es)
ES (1) ES2090031T3 (es)
GR (1) GR3020486T3 (es)
PT (1) PT90373B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ381392A3 (en) * 1990-07-04 1993-12-15 Novo Nordisk As Process for preparing beta-lactams
SK63894A3 (en) * 1991-12-19 1995-03-08 Novo Nordisk As Method of preparation of beta-lactam antibiotic
ZA954839B (en) * 1994-06-10 1996-05-14 Gist Brocades Bv An acylation method
AU3163295A (en) * 1994-07-18 1996-02-16 Gist-Brocades B.V. Process for preparation of beta -lactams at constantly high concentration of reactants
US6320069B1 (en) 1996-07-02 2001-11-20 Toray Industries, Inc. Production of optically active ketone
JP2000512860A (ja) * 1997-04-22 2000-10-03 ギスト ブロカデス ベスローテン フェンノートシャップ β―ラクタム抗生物質を調製する方法
CN103108879B (zh) 2010-09-07 2016-08-17 中化帝斯曼制药有限公司荷兰公司 用于生产头孢菌素类的方法
EP2723882B1 (en) 2011-06-23 2019-05-01 Centrient Pharmaceuticals Netherlands B.V. Process for preparing 3'-thiosubstituted cephalosporins employing a penicillin g acylase
CN103635586A (zh) 2011-06-23 2014-03-12 中化帝斯曼制药有限公司荷兰公司 结晶头孢氧哌唑中间体、其制备方法及其制药用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5343597B1 (es) * 1970-12-25 1978-11-21
JPS5548797B1 (es) * 1971-04-02 1980-12-08
US3904606A (en) * 1973-01-12 1975-09-09 Upjohn Co Process for preparing optically active 6-(' -amino-acetamido)penicillanic acids and 7-(' -aminoacetamido) cephalosporanic acids
JPS51133488A (en) * 1975-05-14 1976-11-19 Shionogi & Co Ltd Process for producing antibiotics enzymatically
JPS591995Y2 (ja) * 1980-02-21 1984-01-19 日立造船株式会社 微細粒を含有する液体の貯溜槽
JPS63294932A (ja) * 1987-05-27 1988-12-01 Niigata Eng Co Ltd スラリーの貯蔵装置
JPS63294933A (ja) * 1987-05-27 1988-12-01 Niigata Eng Co Ltd スラリ−貯槽

Also Published As

Publication number Publication date
EP0339751A1 (en) 1989-11-02
EP0339751B1 (en) 1996-05-29
DK198789D0 (da) 1989-04-25
GR3020486T3 (en) 1996-10-31
PT90373A (pt) 1989-11-10
JP2771244B2 (ja) 1998-07-02
DE68926548D1 (de) 1996-07-04
ATE138690T1 (de) 1996-06-15
DK198789A (da) 1989-10-27
DE68926548T2 (de) 1996-09-26
KR890016184A (ko) 1989-11-28
PT90373B (pt) 1994-09-30
JPH01312998A (ja) 1989-12-18

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