DK175377B1 - Hidtil ukendt S-timolol-derivat samt fremgangsmåde til fremstilling deraf - Google Patents

Hidtil ukendt S-timolol-derivat samt fremgangsmåde til fremstilling deraf Download PDF

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Publication number
DK175377B1
DK175377B1 DK199100725A DK72591A DK175377B1 DK 175377 B1 DK175377 B1 DK 175377B1 DK 199100725 A DK199100725 A DK 199100725A DK 72591 A DK72591 A DK 72591A DK 175377 B1 DK175377 B1 DK 175377B1
Authority
DK
Denmark
Prior art keywords
timolol
hemihydrate
solvent
base
mixture
Prior art date
Application number
DK199100725A
Other languages
Danish (da)
English (en)
Other versions
DK72591D0 (da
DK72591A (da
Inventor
Markku Peraelampi
Original Assignee
Santen Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharma Co Ltd filed Critical Santen Pharma Co Ltd
Publication of DK72591D0 publication Critical patent/DK72591D0/da
Publication of DK72591A publication Critical patent/DK72591A/da
Application granted granted Critical
Publication of DK175377B1 publication Critical patent/DK175377B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/10—1,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Control Of El Displays (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
DK199100725A 1988-10-20 1991-04-19 Hidtil ukendt S-timolol-derivat samt fremgangsmåde til fremstilling deraf DK175377B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FI884838 1988-10-20
FI884838A FI82240C (fi) 1988-10-20 1988-10-20 Foerfarande foer framstaellning av farmakologiskt vaerdefullt s-timolol-hemihydrat.
PCT/FI1989/000196 WO1990004592A1 (en) 1988-10-20 1989-10-13 Novel s-timolol derivative and process for its preparation
FI8900196 1989-10-13

Publications (3)

Publication Number Publication Date
DK72591D0 DK72591D0 (da) 1991-04-19
DK72591A DK72591A (da) 1991-04-19
DK175377B1 true DK175377B1 (da) 2004-09-20

Family

ID=8527232

Family Applications (1)

Application Number Title Priority Date Filing Date
DK199100725A DK175377B1 (da) 1988-10-20 1991-04-19 Hidtil ukendt S-timolol-derivat samt fremgangsmåde til fremstilling deraf

Country Status (12)

Country Link
US (4) US5231095A (ja)
EP (1) EP0440684B1 (ja)
JP (1) JP2949508B2 (ja)
AT (1) ATE112277T1 (ja)
AU (1) AU624431B2 (ja)
CA (1) CA2001083C (ja)
DE (1) DE68918597T2 (ja)
DK (1) DK175377B1 (ja)
FI (1) FI82240C (ja)
NO (1) NO179838C (ja)
NZ (1) NZ231057A (ja)
WO (1) WO1990004592A1 (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI82240C (fi) * 1988-10-20 1991-02-11 Huhtamaeki Oy Foerfarande foer framstaellning av farmakologiskt vaerdefullt s-timolol-hemihydrat.
US5496820A (en) * 1988-10-20 1996-03-05 Peraelampi; Markku Ophthalmic use of S-timolol hemihydrate
TW208013B (ja) * 1990-03-01 1993-06-21 Daiichi Co Ltd
ATE154513T1 (de) * 1992-07-08 1997-07-15 Leiras Oy Augenarzneimittel enthaltend timolol hemihydrat
US20060143783A1 (en) * 2004-12-15 2006-07-06 Berman Paul K Energy diffusing glove insert
US7862552B2 (en) 2005-05-09 2011-01-04 Boston Scientific Scimed, Inc. Medical devices for treating urological and uterine conditions
EP2130828A4 (en) 2007-02-28 2010-12-29 Asahi Kasei Pharma Corp sulfonamide

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3657237A (en) * 1968-05-22 1972-04-18 Frosst & Co Charles E Process for making 1 2 5-thiadiazoles in the sinister configuration
US4428883A (en) * 1981-03-06 1984-01-31 The University Of Kentucky Research Foundation Novel method of administering β-blockers and novel dosage forms containing same
FI71933C (fi) * 1984-03-30 1989-04-06 Star Oy Ab Nya l-vinsyra-0-monoestrar av 3-morfolino-4-(3'-tert.-butylamino-2'-hydroxipropoxi)-1,2,5-tiadiazol och deras anvaendning saosom mellanprodukter.
JPS60226855A (ja) * 1984-04-26 1985-11-12 Nippon Kayaku Co Ltd Ｎ−ベンジルオキシカルボニル−ｌ−スレオニンアミド・１／２水和物およびその製造法
US4752478A (en) * 1984-12-17 1988-06-21 Merck & Co., Inc. Transdermal system for timolol
US4756710A (en) * 1985-04-05 1988-07-12 Merck & Co., Inc. pH-Mediated drug delivery system
FI82240C (fi) * 1988-10-20 1991-02-11 Huhtamaeki Oy Foerfarande foer framstaellning av farmakologiskt vaerdefullt s-timolol-hemihydrat.

Also Published As

Publication number Publication date
NZ231057A (en) 1990-11-27
FI884838A (fi) 1990-04-21
US5574035A (en) 1996-11-12
US5354860A (en) 1994-10-11
ATE112277T1 (de) 1994-10-15
JPH04502612A (ja) 1992-05-14
US5541184A (en) 1996-07-30
FI884838A0 (fi) 1988-10-20
JP2949508B2 (ja) 1999-09-13
NO911508L (no) 1991-04-17
DE68918597T2 (de) 1995-05-11
DE68918597D1 (de) 1994-11-03
NO911508D0 (no) 1991-04-17
DK72591D0 (da) 1991-04-19
EP0440684B1 (en) 1994-09-28
CA2001083A1 (en) 1990-04-20
FI82240B (fi) 1990-10-31
WO1990004592A1 (en) 1990-05-03
FI82240C (fi) 1991-02-11
EP0440684A1 (en) 1991-08-14
NO179838B (no) 1996-09-16
CA2001083C (en) 1999-06-15
NO179838C (no) 1996-12-27
AU4347389A (en) 1990-05-14
AU624431B2 (en) 1992-06-11
DK72591A (da) 1991-04-19
US5231095A (en) 1993-07-27

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