DK174523B1 - Anvendelse af gamma-interferon til fremstilling af et lægemiddel til behandling af vasculær stenosis - Google Patents
Anvendelse af gamma-interferon til fremstilling af et lægemiddel til behandling af vasculær stenosis Download PDFInfo
- Publication number
- DK174523B1 DK174523B1 DK199100562A DK56291A DK174523B1 DK 174523 B1 DK174523 B1 DK 174523B1 DK 199100562 A DK199100562 A DK 199100562A DK 56291 A DK56291 A DK 56291A DK 174523 B1 DK174523 B1 DK 174523B1
- Authority
- DK
- Denmark
- Prior art keywords
- cells
- gamma interferon
- smooth muscle
- cell
- expression
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
- A61K38/217—IFN-gamma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Radiation-Therapy Devices (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8803472A SE462364B (sv) | 1988-09-30 | 1988-09-30 | Anvaendning av gamma-interferon foer beredning av ett preparat foer behandling av vaskulaer stenos |
SE8803472 | 1988-09-30 | ||
PCT/SE1989/000520 WO1990003189A1 (fr) | 1988-09-30 | 1989-09-27 | Utilisation de gamma-interferon pour le traitement de stenose vasculaire |
SE8900520 | 1989-09-27 |
Publications (3)
Publication Number | Publication Date |
---|---|
DK56291D0 DK56291D0 (da) | 1991-03-27 |
DK56291A DK56291A (da) | 1991-05-24 |
DK174523B1 true DK174523B1 (da) | 2003-05-12 |
Family
ID=20373494
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK199100562A DK174523B1 (da) | 1988-09-30 | 1991-03-27 | Anvendelse af gamma-interferon til fremstilling af et lægemiddel til behandling af vasculær stenosis |
Country Status (18)
Country | Link |
---|---|
US (1) | US5208019A (fr) |
EP (1) | EP0367735B1 (fr) |
JP (1) | JP2895896B2 (fr) |
KR (1) | KR0137017B1 (fr) |
AT (1) | ATE86869T1 (fr) |
AU (1) | AU623181B2 (fr) |
CA (1) | CA1338722C (fr) |
DD (1) | DD288094A5 (fr) |
DE (1) | DE68905438T2 (fr) |
DK (1) | DK174523B1 (fr) |
HU (1) | HU206988B (fr) |
IE (1) | IE63874B1 (fr) |
IL (1) | IL91796A (fr) |
NZ (1) | NZ230816A (fr) |
PH (1) | PH26293A (fr) |
PT (1) | PT91863B (fr) |
SE (1) | SE462364B (fr) |
WO (1) | WO1990003189A1 (fr) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5811447A (en) | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6515009B1 (en) | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
CA2131550A1 (fr) * | 1992-02-05 | 1993-08-19 | Andrew Zalewski | Therapie genique a l'interferon pour le traitement des troubles vasculaires |
US6395494B1 (en) * | 1993-05-13 | 2002-05-28 | Neorx Corporation | Method to determine TGF-β |
US5770609A (en) * | 1993-01-28 | 1998-06-23 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
US6306421B1 (en) | 1992-09-25 | 2001-10-23 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6251920B1 (en) | 1993-05-13 | 2001-06-26 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
US5957972A (en) * | 1992-09-29 | 1999-09-28 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Implants possessing a surface of endothelial cells genetically-modified to inhibit intimal thickening |
JPH08505397A (ja) * | 1993-01-07 | 1996-06-11 | トーマス ジェファーソン ユニバーシティ | 平滑筋細胞の増殖を調節するためのc‐mycのアンチセンス阻害 |
US6663881B2 (en) | 1993-01-28 | 2003-12-16 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US5595722A (en) * | 1993-01-28 | 1997-01-21 | Neorx Corporation | Method for identifying an agent which increases TGF-beta levels |
US5981568A (en) | 1993-01-28 | 1999-11-09 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
US6491938B2 (en) | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
DE69435137D1 (de) * | 1993-05-13 | 2008-10-16 | Poniard Pharmaceuticals Inc | Prävention und behandlung von pathologien, die mit einer abnormalen proliferationglatter muskelzellen verbunden sind |
US6133242A (en) * | 1993-10-15 | 2000-10-17 | Thomas Jefferson Univerisity | Inhibition of extracellular matrix synthesis by antisense compounds directed to nuclear proto-oncogenes |
US6323184B1 (en) | 1993-10-15 | 2001-11-27 | Thomas Jefferson University | Arteriovenous and venous graft treatments: methods and compositions |
US5449679A (en) * | 1994-07-29 | 1995-09-12 | Leonard; Robert J. | Process and products for reducing biological fluid levels of a lipid soluble waste |
US5665591A (en) * | 1994-12-06 | 1997-09-09 | Trustees Of Boston University | Regulation of smooth muscle cell proliferation |
JPH11510479A (ja) | 1995-06-07 | 1999-09-14 | ネオルックス コーポレイション | タモキシフェン類似体による心臓血管疾病の予防及び治療 |
US7611533B2 (en) * | 1995-06-07 | 2009-11-03 | Cook Incorporated | Coated implantable medical device |
EP0797998A4 (fr) * | 1995-11-17 | 2003-01-15 | Toray Industries | Protection des cellules endotheliales |
US5681558A (en) * | 1995-11-30 | 1997-10-28 | Berlex Laboratories, Inc. | Method of using beta-interferons to treat restenosis |
DE69932235T2 (de) | 1998-04-02 | 2007-06-14 | Genentech, Inc., South San Francisco | Behandlung von herzhypertrophie |
US7524826B2 (en) * | 2000-04-14 | 2009-04-28 | Mcmaster University And Hamilton Health Sciences Corporation | Method of inhibiting the generation of active thrombin on the surface of a cell within an atherosclerotic plaque |
AU2002310922A1 (en) * | 2001-05-04 | 2002-11-18 | Institute Of Molecular And Cell Biology | Interferons in the treatment of ischemia |
JP2007519422A (ja) | 2004-02-02 | 2007-07-19 | アンブレツクス・インコーポレイテツド | 修飾されたヒト四螺旋バンドルポリペプチド及びそれらの使用 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3261761D1 (en) * | 1981-07-14 | 1985-02-14 | Efamol Ltd | Pharmaceutical and dietary composition when used for enhancement of 1-series pg production |
US5096705A (en) * | 1981-10-19 | 1992-03-17 | Genentech, Inc. | Human immune interferon |
US4454115A (en) * | 1981-10-23 | 1984-06-12 | Wisconsin Alumni Research Foundation | Method of reducing the level of low density lipoproteins in the serum of a patient |
US4483849A (en) * | 1983-01-07 | 1984-11-20 | Carter William A | Stabilization and purification of interferon with propylene glycol, resulting in a non-toxic product |
JPS6069037A (ja) * | 1983-09-26 | 1985-04-19 | Sunstar Inc | エリテマト−デス治療用外用剤 |
US4680175A (en) * | 1984-02-07 | 1987-07-14 | Interferon Sciences, Inc. | Interferon administration vehicles |
US4605555A (en) * | 1984-09-20 | 1986-08-12 | Sun Star Kabushiki Kaisha | Composition and method for treating keratosic disorder of skin and mucosa |
US4946674A (en) * | 1984-10-05 | 1990-08-07 | Bioferon Biochemische Substanzen Gmbh & Co. | Process for treatment of rheumatic diseases |
IL78444A (en) * | 1986-04-08 | 1992-05-25 | Yeda Res & Dev | Human gamma interferon-specific receptor protein,antibody against said protein,and compositions containing said protein and antibody |
US5026544A (en) * | 1988-02-16 | 1991-06-25 | Board Of Reagents, The University Of Texas System | Methods and compositions for inhibiting the growth of neoplastic cells |
-
1988
- 1988-09-30 SE SE8803472A patent/SE462364B/sv not_active IP Right Cessation
-
1989
- 1989-09-27 AU AU43051/89A patent/AU623181B2/en not_active Expired
- 1989-09-27 JP JP1510051A patent/JP2895896B2/ja not_active Expired - Lifetime
- 1989-09-27 HU HU895542A patent/HU206988B/hu not_active IP Right Cessation
- 1989-09-27 DE DE89850317T patent/DE68905438T2/de not_active Expired - Lifetime
- 1989-09-27 IL IL9179689A patent/IL91796A/en not_active IP Right Cessation
- 1989-09-27 AT AT89850317T patent/ATE86869T1/de not_active IP Right Cessation
- 1989-09-27 KR KR1019900701144A patent/KR0137017B1/ko not_active IP Right Cessation
- 1989-09-27 US US07/671,786 patent/US5208019A/en not_active Expired - Lifetime
- 1989-09-27 EP EP89850317A patent/EP0367735B1/fr not_active Expired - Lifetime
- 1989-09-27 WO PCT/SE1989/000520 patent/WO1990003189A1/fr active Application Filing
- 1989-09-28 DD DD89333072A patent/DD288094A5/de unknown
- 1989-09-28 NZ NZ230816A patent/NZ230816A/en unknown
- 1989-09-29 CA CA000614859A patent/CA1338722C/fr not_active Expired - Lifetime
- 1989-09-29 PT PT91863A patent/PT91863B/pt not_active IP Right Cessation
- 1989-09-29 IE IE312389A patent/IE63874B1/en not_active IP Right Cessation
- 1989-09-29 PH PH39308A patent/PH26293A/en unknown
-
1991
- 1991-03-27 DK DK199100562A patent/DK174523B1/da not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
NZ230816A (en) | 1997-06-24 |
IE893123L (en) | 1990-03-30 |
US5208019A (en) | 1993-05-04 |
DK56291D0 (da) | 1991-03-27 |
JP2895896B2 (ja) | 1999-05-24 |
AU4305189A (en) | 1990-04-18 |
JPH04500966A (ja) | 1992-02-20 |
PT91863B (pt) | 1995-05-31 |
PT91863A (pt) | 1990-03-30 |
KR0137017B1 (ko) | 1998-04-25 |
AU623181B2 (en) | 1992-05-07 |
DE68905438D1 (de) | 1993-04-22 |
CA1338722C (fr) | 1996-11-19 |
HUT57063A (en) | 1991-11-28 |
DE68905438T2 (de) | 1993-09-30 |
DK56291A (da) | 1991-05-24 |
IE63874B1 (en) | 1995-06-14 |
ATE86869T1 (de) | 1993-04-15 |
SE8803472D0 (sv) | 1988-09-30 |
IL91796A (en) | 1994-10-07 |
IL91796A0 (en) | 1990-06-10 |
PH26293A (en) | 1992-04-10 |
HU895542D0 (en) | 1991-10-28 |
DD288094A5 (de) | 1991-03-21 |
SE462364B (sv) | 1990-06-18 |
EP0367735B1 (fr) | 1993-03-17 |
EP0367735A1 (fr) | 1990-05-09 |
KR900701308A (ko) | 1990-12-01 |
WO1990003189A1 (fr) | 1990-04-05 |
HU206988B (en) | 1993-03-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUP | Patent expired |