DK172313B1 - Fremgangsmåde til enantiospecifik fremstilling af (S)-2-ethylamino-1-[3-(trifluormethyl)phenyl]propan samt mellemprodukter til brug ved fremgangsmåden - Google Patents

Fremgangsmåde til enantiospecifik fremstilling af (S)-2-ethylamino-1-[3-(trifluormethyl)phenyl]propan samt mellemprodukter til brug ved fremgangsmåden Download PDF

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Publication number
DK172313B1
DK172313B1 DK373888A DK373888A DK172313B1 DK 172313 B1 DK172313 B1 DK 172313B1 DK 373888 A DK373888 A DK 373888A DK 373888 A DK373888 A DK 373888A DK 172313 B1 DK172313 B1 DK 172313B1
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DK
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Prior art keywords
ethylamino
formula
propane
propanol
trifluoromethyl
Prior art date
Application number
DK373888A
Other languages
Danish (da)
English (en)
Other versions
DK373888D0 (da
DK373888A (da
Inventor
Claude Fugier
Michel Leroux
Robert Mauge
Alexandre Alexakis
Jean-Francois Normant
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of DK373888D0 publication Critical patent/DK373888D0/da
Publication of DK373888A publication Critical patent/DK373888A/da
Application granted granted Critical
Publication of DK172313B1 publication Critical patent/DK172313B1/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/04Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
    • C07C215/06Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
    • C07C215/08Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with only one hydroxy group and one amino group bound to the carbon skeleton

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK373888A 1987-07-16 1988-07-05 Fremgangsmåde til enantiospecifik fremstilling af (S)-2-ethylamino-1-[3-(trifluormethyl)phenyl]propan samt mellemprodukter til brug ved fremgangsmåden DK172313B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8710020A FR2618148B1 (fr) 1987-07-16 1987-07-16 Nouveau procede de preparation enantiospecifique du (s) ethylamino-2 (trifluoromethyl-3 phenyl)-1 propane
FR8710020 1987-07-16

Publications (3)

Publication Number Publication Date
DK373888D0 DK373888D0 (da) 1988-07-05
DK373888A DK373888A (da) 1989-01-17
DK172313B1 true DK172313B1 (da) 1998-03-16

Family

ID=9353184

Family Applications (1)

Application Number Title Priority Date Filing Date
DK373888A DK172313B1 (da) 1987-07-16 1988-07-05 Fremgangsmåde til enantiospecifik fremstilling af (S)-2-ethylamino-1-[3-(trifluormethyl)phenyl]propan samt mellemprodukter til brug ved fremgangsmåden

Country Status (13)

Country Link
EP (1) EP0301925B1 (pt)
AT (1) ATE68783T1 (pt)
AU (1) AU602101B2 (pt)
DE (1) DE3865765D1 (pt)
DK (1) DK172313B1 (pt)
ES (1) ES2009944A6 (pt)
FR (1) FR2618148B1 (pt)
GR (1) GR1002241B (pt)
IE (1) IE59990B1 (pt)
NZ (1) NZ224499A (pt)
OA (1) OA08845A (pt)
PT (1) PT88011B (pt)
ZA (1) ZA883484B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1292595B1 (it) * 1997-06-03 1999-02-08 Alfa Chem Ital Processo per la produzione della dexfenfluramina cloridrato.
EP3170807B1 (en) 2015-11-23 2019-12-11 Frau Pharma S.r.l. New method for synthesis of fenfluramine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH204708A (de) * 1937-07-21 1939-05-15 Chem Fab Vormals Sandoz Verfahren zur Darstellung eines Aminoalkohols.
US3198834A (en) * 1964-07-27 1965-08-03 Snc Science Union Et Compagnie Optical isomers of trifluoromethylated phenethylamines
US3792048A (en) * 1970-10-29 1974-02-12 Pacific Res Labor Process for hydrolyzing 3-trifluoromethyl phenethylamines

Also Published As

Publication number Publication date
NZ224499A (en) 1990-07-26
GR880100293A (el) 1989-04-12
EP0301925A1 (fr) 1989-02-01
IE881335L (en) 1989-01-16
DE3865765D1 (de) 1991-11-28
ES2009944A6 (es) 1989-10-16
EP0301925B1 (fr) 1991-10-23
DK373888D0 (da) 1988-07-05
GR1002241B (en) 1996-04-22
ZA883484B (en) 1988-11-21
IE59990B1 (en) 1994-05-18
AU1908388A (en) 1989-01-19
PT88011A (pt) 1989-06-30
FR2618148B1 (fr) 1989-10-27
ATE68783T1 (de) 1991-11-15
AU602101B2 (en) 1990-09-27
PT88011B (pt) 1995-03-01
DK373888A (da) 1989-01-17
FR2618148A1 (fr) 1989-01-20
OA08845A (fr) 1989-03-31

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B1 Patent granted (law 1993)
PBP Patent lapsed

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