DK1720544T3 - Nye azabicykliske derivater, fremstillingsmetode hertil og farmaceutiske sammensætninger indeholdende disse - Google Patents
Nye azabicykliske derivater, fremstillingsmetode hertil og farmaceutiske sammensætninger indeholdende disseInfo
- Publication number
- DK1720544T3 DK1720544T3 DK05717646T DK05717646T DK1720544T3 DK 1720544 T3 DK1720544 T3 DK 1720544T3 DK 05717646 T DK05717646 T DK 05717646T DK 05717646 T DK05717646 T DK 05717646T DK 1720544 T3 DK1720544 T3 DK 1720544T3
- Authority
- DK
- Denmark
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- azabicyclic derivatives
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Psychology (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0401690A FR2866647B1 (fr) | 2004-02-20 | 2004-02-20 | Nouveaux derives azabicycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
PCT/FR2005/000382 WO2005089747A1 (fr) | 2004-02-20 | 2005-02-18 | Nouveaux derives azabicycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
Publication Number | Publication Date |
---|---|
DK1720544T3 true DK1720544T3 (da) | 2008-07-21 |
Family
ID=34833930
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK05717646T DK1720544T3 (da) | 2004-02-20 | 2005-02-18 | Nye azabicykliske derivater, fremstillingsmetode hertil og farmaceutiske sammensætninger indeholdende disse |
Country Status (30)
Country | Link |
---|---|
US (1) | US7576120B2 (sr) |
EP (1) | EP1720544B1 (sr) |
JP (1) | JP4519861B2 (sr) |
KR (1) | KR100885104B1 (sr) |
CN (2) | CN101230033B (sr) |
AR (3) | AR047685A1 (sr) |
AT (1) | ATE389398T1 (sr) |
AU (1) | AU2005224129B2 (sr) |
BR (1) | BRPI0507830A (sr) |
CA (1) | CA2555216C (sr) |
CY (1) | CY1108529T1 (sr) |
DE (1) | DE602005005456T2 (sr) |
DK (1) | DK1720544T3 (sr) |
EA (1) | EA010300B1 (sr) |
ES (1) | ES2303233T3 (sr) |
FR (1) | FR2866647B1 (sr) |
GE (1) | GEP20094578B (sr) |
HK (1) | HK1123789A1 (sr) |
HR (1) | HRP20080184T5 (sr) |
MA (1) | MA28342A1 (sr) |
ME (1) | ME01400B (sr) |
MY (1) | MY137282A (sr) |
NO (1) | NO337013B1 (sr) |
NZ (1) | NZ548898A (sr) |
PL (1) | PL1720544T3 (sr) |
PT (1) | PT1720544E (sr) |
RS (1) | RS50577B (sr) |
SI (1) | SI1720544T1 (sr) |
WO (1) | WO2005089747A1 (sr) |
ZA (1) | ZA200606558B (sr) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1717234A1 (en) * | 2005-04-29 | 2006-11-02 | Bioprojet | Phenoxypropylpiperidines and -pyrrolidines and their use as histamine H3-receptor ligands |
EP1717235A3 (en) | 2005-04-29 | 2007-02-28 | Bioprojet | Phenoxypropylpiperidines and -pyrrolidines and their use as histamine H3-receptor ligands |
WO2008116145A2 (en) * | 2007-03-22 | 2008-09-25 | Arete Therapeutics, Inc. | Soluble epoxide hydrolase inhibitors |
FR2932479A1 (fr) * | 2008-06-13 | 2009-12-18 | Servier Lab | Nouveaux derives azabicycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
FR2937251B1 (fr) * | 2008-10-16 | 2011-03-18 | Servier Lab | Utilisation du 4-{3-°hexahydrocyclopenta°c!pyrrol-2(1h)-yl! propoxy}benzamide pour l'obtention de medicaments destines au traitement des troubles du sommeil |
FR2953514B1 (fr) * | 2009-12-09 | 2011-12-23 | Servier Lab | Nouveaux derives azabicyclo[3.2.0]hept-3-yl, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2953513B1 (fr) * | 2009-12-09 | 2011-12-23 | Servier Lab | Nouveaux derives azabicyclo[3.2.0]hept-6-yl, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2953521B1 (fr) * | 2009-12-09 | 2011-11-18 | Servier Lab | Nouveaux derives azabicyclo[3.1.0]hex-2-yl, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2953515B1 (fr) * | 2009-12-09 | 2011-12-23 | Servier Lab | Nouveaux derives du type hexahydrocyclopenta[b]pyrrole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
FR2974729B1 (fr) * | 2011-05-02 | 2013-04-19 | Servier Lab | Nouvelle association entre le 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1h)-yl]propoxy}benzamide et un inhibiteur de l'acetylcholinesterase et les compositions pharmaceutiques qui la contiennent |
FR2976286B1 (fr) | 2011-06-08 | 2013-05-24 | Servier Lab | 4-{3-[trans-hexahydrocyclopenta[c]pyrrol-2(1h)-yl]propoxy}benzamide, son procede de preparation et les compositions pharmaceutiques qui le contiennent |
FR2976285B1 (fr) * | 2011-06-08 | 2013-05-24 | Servier Lab | Procede de synthese et forme cristalline du chlorhydrate de 4-{3-[cis-hexahydrocypenta[c]pyrrol-2(1h)-yl]propoxy}benzamide ainsi que les compositions pharmaceutiques qui la contiennent |
BR112014013461A2 (pt) | 2011-12-08 | 2017-06-13 | Taisho Pharmaceutical Co Ltd | derivado de fenilpirrol |
FR2983732B1 (fr) * | 2011-12-09 | 2013-11-22 | Servier Lab | Nouvelle association entre le 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1h)-yl]propoxy}pharmaceutiques qui la contiennent |
WO2013100054A1 (ja) * | 2011-12-27 | 2013-07-04 | 大正製薬株式会社 | フェニルトリアゾール誘導体 |
CN103183632A (zh) * | 2011-12-29 | 2013-07-03 | 山东方明药业集团股份有限公司 | 一种3-氮杂双环辛烷盐酸盐的提纯方法 |
FR2999179A1 (fr) * | 2012-12-07 | 2014-06-13 | Servier Lab | Procede de synthese d'un sel d'addition a un acide pharmaceutiquement acceptable du 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1h)-yl]propoxy}benzamide, ainsi que les formes cristallines associees |
FR3003466B1 (fr) * | 2013-03-22 | 2015-08-07 | Servier Lab | Utilisation du 4-{3-[cis-hexahydrocyclopenta[c]pyrrol-2(1h)-yl]propoxy}benzamide pour le traitement des douleurs neuropathiques |
EP3594205A1 (en) | 2018-07-09 | 2020-01-15 | Abivax | Phenyl-n-aryl derivatives for treating a rna virus infection |
EP3594206A1 (en) * | 2018-07-09 | 2020-01-15 | Abivax | Phenyl-n-quinoline derivatives for treating a rna virus infection |
CN111377911B (zh) * | 2018-12-27 | 2022-05-24 | 江苏恩华药业股份有限公司 | 一种吗啉苯甲酰胺类化合物及其应用 |
CN111377846B (zh) * | 2018-12-27 | 2022-05-24 | 江苏恩华药业股份有限公司 | 一种哌嗪苯甲酰胺类衍生物及其应用 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2962496A (en) * | 1957-01-28 | 1960-11-29 | Geschickter Fund Med Res | Nu-substituted-3-azabicyclooctanes [3: 3: 0] and salts thereof |
DE4341403A1 (de) * | 1993-12-04 | 1995-06-08 | Basf Ag | N-substituierte 3-Azabicycloalkan-Derivate, ihre Herstellung und Verwendung |
ATE302751T1 (de) * | 2000-06-30 | 2005-09-15 | Elan Pharm Inc | Verbindungen zur behandlung der alzheimerischen krankheit |
JP4516717B2 (ja) * | 2000-07-13 | 2010-08-04 | アボット・ラボラトリーズ | ヒスタミン−3受容体リガンドとしての1,3−二置換ピロリジン及び1,3,3−三置換ピロリジン並びにそれらの治療的応用 |
FR2827288B1 (fr) * | 2001-07-12 | 2003-10-31 | Servier Lab | Nouveaux derives d'octahydro-2h-pyrido[1,2-a]pyrazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
2004
- 2004-02-20 FR FR0401690A patent/FR2866647B1/fr not_active Expired - Fee Related
-
2005
- 2005-02-18 DE DE602005005456T patent/DE602005005456T2/de active Active
- 2005-02-18 AT AT05717646T patent/ATE389398T1/de active
- 2005-02-18 EA EA200601512A patent/EA010300B1/ru not_active IP Right Cessation
- 2005-02-18 KR KR1020067019301A patent/KR100885104B1/ko not_active IP Right Cessation
- 2005-02-18 CN CN2008100828098A patent/CN101230033B/zh not_active Expired - Fee Related
- 2005-02-18 PL PL05717646T patent/PL1720544T3/pl unknown
- 2005-02-18 AU AU2005224129A patent/AU2005224129B2/en not_active Ceased
- 2005-02-18 PT PT05717646T patent/PT1720544E/pt unknown
- 2005-02-18 WO PCT/FR2005/000382 patent/WO2005089747A1/fr active Application Filing
- 2005-02-18 AR ARP050100585A patent/AR047685A1/es active IP Right Grant
- 2005-02-18 ES ES05717646T patent/ES2303233T3/es active Active
- 2005-02-18 CA CA2555216A patent/CA2555216C/fr not_active Expired - Fee Related
- 2005-02-18 NZ NZ548898A patent/NZ548898A/en not_active IP Right Cessation
- 2005-02-18 ME MEP-2008-947A patent/ME01400B/me unknown
- 2005-02-18 DK DK05717646T patent/DK1720544T3/da active
- 2005-02-18 CN CN200580005456A patent/CN100577160C/zh not_active Expired - Fee Related
- 2005-02-18 GE GEAP20059627A patent/GEP20094578B/en unknown
- 2005-02-18 EP EP05717646A patent/EP1720544B1/fr active Active
- 2005-02-18 MY MYPI20050619A patent/MY137282A/en unknown
- 2005-02-18 JP JP2006553623A patent/JP4519861B2/ja not_active Expired - Fee Related
- 2005-02-18 SI SI200530217T patent/SI1720544T1/sl unknown
- 2005-02-18 RS RSP-2008/0226A patent/RS50577B/sr unknown
- 2005-02-18 BR BRPI0507830-0A patent/BRPI0507830A/pt not_active IP Right Cessation
- 2005-02-20 US US10/589,831 patent/US7576120B2/en not_active Expired - Fee Related
-
2006
- 2006-08-03 MA MA29229A patent/MA28342A1/fr unknown
- 2006-08-07 ZA ZA2006/06558A patent/ZA200606558B/en unknown
- 2006-09-14 NO NO20064160A patent/NO337013B1/no not_active IP Right Cessation
-
2008
- 2008-04-22 HR HR20080184T patent/HRP20080184T5/xx unknown
- 2008-05-20 CY CY20081100520T patent/CY1108529T1/el unknown
-
2009
- 2009-01-09 HK HK09100237.4A patent/HK1123789A1/xx not_active IP Right Cessation
-
2012
- 2012-12-26 AR ARP120104964A patent/AR089451A2/es unknown
-
2014
- 2014-01-28 AR ARP140100250A patent/AR094601A2/es unknown
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