DK171392B1 - Anvendelse af N-(2-hydroxyethyl)nicotinamidnitrat eller et farmaceutisk acceptabelt salt deraf til fremstilling af et farmaceutisk præparat til forøgelse af hjernens glucoseoptagelse - Google Patents

Anvendelse af N-(2-hydroxyethyl)nicotinamidnitrat eller et farmaceutisk acceptabelt salt deraf til fremstilling af et farmaceutisk præparat til forøgelse af hjernens glucoseoptagelse Download PDF

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Publication number
DK171392B1
DK171392B1 DK441987A DK441987A DK171392B1 DK 171392 B1 DK171392 B1 DK 171392B1 DK 441987 A DK441987 A DK 441987A DK 441987 A DK441987 A DK 441987A DK 171392 B1 DK171392 B1 DK 171392B1
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DK
Denmark
Prior art keywords
hydroxyethyl
brain
cerebral
nitrate
pharmaceutical composition
Prior art date
Application number
DK441987A
Other languages
Danish (da)
English (en)
Other versions
DK441987D0 (da
DK441987A (da
Inventor
Yukifumi Noda
Hiroyuki Nabata
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of DK441987D0 publication Critical patent/DK441987D0/da
Publication of DK441987A publication Critical patent/DK441987A/da
Application granted granted Critical
Publication of DK171392B1 publication Critical patent/DK171392B1/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465Nicotine; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
DK441987A 1986-08-27 1987-08-25 Anvendelse af N-(2-hydroxyethyl)nicotinamidnitrat eller et farmaceutisk acceptabelt salt deraf til fremstilling af et farmaceutisk præparat til forøgelse af hjernens glucoseoptagelse DK171392B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP19879686 1986-08-27
JP19879686 1986-08-27

Publications (3)

Publication Number Publication Date
DK441987D0 DK441987D0 (da) 1987-08-25
DK441987A DK441987A (da) 1988-02-28
DK171392B1 true DK171392B1 (da) 1996-10-14

Family

ID=16397046

Family Applications (1)

Application Number Title Priority Date Filing Date
DK441987A DK171392B1 (da) 1986-08-27 1987-08-25 Anvendelse af N-(2-hydroxyethyl)nicotinamidnitrat eller et farmaceutisk acceptabelt salt deraf til fremstilling af et farmaceutisk præparat til forøgelse af hjernens glucoseoptagelse

Country Status (22)

Country Link
US (1) US4870090A (ja)
JP (1) JPH07121863B2 (ja)
KR (1) KR950002151B1 (ja)
AU (1) AU603375B2 (ja)
BE (1) BE1003959A5 (ja)
CA (1) CA1302888C (ja)
CH (1) CH672069A5 (ja)
DE (1) DE3728499A1 (ja)
DK (1) DK171392B1 (ja)
FI (1) FI873727A (ja)
FR (1) FR2605222B1 (ja)
GB (1) GB2195532B (ja)
HK (1) HK64993A (ja)
IE (1) IE60601B1 (ja)
IT (1) IT1211477B (ja)
LU (1) LU86973A1 (ja)
NL (1) NL8701994A (ja)
NO (1) NO873571L (ja)
NZ (1) NZ221564A (ja)
SE (1) SE502323C2 (ja)
SG (1) SG52393G (ja)
ZA (1) ZA876401B (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5736529A (en) * 1996-03-22 1998-04-07 Neurocal International Inc. Use of NAD-related compounds in the treatment of neural trauma to inhibit neurodegeneration
US6329349B1 (en) * 1997-10-23 2001-12-11 Trustees Of The University Of Pennsylvania Methods for reducing ischemic injury of the heart via the sequential administration of monophosphoryl lipid A and adenosine receptor agents
US6417207B1 (en) 1999-05-12 2002-07-09 Nitromed, Inc. Nitrosated and nitrosylated potassium channel activators, compositions and methods of use
CN107773545A (zh) * 2016-08-29 2018-03-09 烟台益诺依生物医药科技有限公司 依达拉奉与(+)‑2‑莰醇的舌下用药物组合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200640A (en) * 1976-04-02 1980-04-29 Chugai Seiyaku Kabushiki Kaisha Nitric ester of N-(2-hydroxyethyl)nicotinamide and pharmaceutical use
GB1562962A (en) * 1976-04-02 1980-03-19 Chugai Pharmaceutical Co Ltd Nicotinamide derivatives processes for producting the same and pharmaceutical compositions containing the same
EP0223811A1 (en) * 1985-05-22 1987-06-03 Beecham Group Plc Use of nicorandil or pinacidil for the treatment of peripheral vascular disease
US4696934A (en) * 1986-01-10 1987-09-29 Warner-Lambert Company Method for using nifedipine for treating stroke
WO1987005508A1 (en) * 1986-03-14 1987-09-24 Medical College Of Wisconsin Research Foundation, Method of treatment and prevention of cerebral vasospasms

Also Published As

Publication number Publication date
ZA876401B (en) 1988-04-27
JPH07121863B2 (ja) 1995-12-25
CA1302888C (en) 1992-06-09
BE1003959A5 (fr) 1992-07-22
FR2605222B1 (fr) 1991-02-22
KR880002525A (ko) 1988-05-09
NZ221564A (en) 1999-08-30
IE872218L (en) 1988-02-27
CH672069A5 (ja) 1989-10-31
FI873727A0 (fi) 1987-08-27
JPS63152317A (ja) 1988-06-24
US4870090A (en) 1989-09-26
NO873571D0 (no) 1987-08-24
IT1211477B (it) 1989-11-03
NO873571L (no) 1988-02-29
AU7731187A (en) 1988-03-03
IT8767725A0 (it) 1987-08-21
SE8703308D0 (sv) 1987-08-26
DE3728499A1 (de) 1988-03-03
FI873727A (fi) 1988-02-28
FR2605222A1 (fr) 1988-04-22
SE8703308L (sv) 1988-02-28
GB2195532A (en) 1988-04-13
AU603375B2 (en) 1990-11-15
SG52393G (en) 1993-08-06
HK64993A (en) 1993-07-16
KR950002151B1 (ko) 1995-03-14
DK441987D0 (da) 1987-08-25
DK441987A (da) 1988-02-28
IE60601B1 (en) 1994-07-27
SE502323C2 (sv) 1995-10-02
NL8701994A (nl) 1988-03-16
GB2195532B (en) 1990-05-23
LU86973A1 (fr) 1987-12-16
GB8720219D0 (en) 1987-10-07

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B1 Patent granted (law 1993)
PBP Patent lapsed

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