FR2605222B1 - Agent therapeutique a base de nitrate de n-(2-hydroxyethyl) nicotinamide pour le traitement de troubles associes a l'ischemie cerebrale - Google Patents

Agent therapeutique a base de nitrate de n-(2-hydroxyethyl) nicotinamide pour le traitement de troubles associes a l'ischemie cerebrale

Info

Publication number
FR2605222B1
FR2605222B1 FR878711957A FR8711957A FR2605222B1 FR 2605222 B1 FR2605222 B1 FR 2605222B1 FR 878711957 A FR878711957 A FR 878711957A FR 8711957 A FR8711957 A FR 8711957A FR 2605222 B1 FR2605222 B1 FR 2605222B1
Authority
FR
France
Prior art keywords
nicotinamide
hydroxyethyl
treatment
therapeutic agent
disorders associated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR878711957A
Other languages
English (en)
Other versions
FR2605222A1 (fr
Inventor
Yukifumi Noda
Hiroyuki Nabata
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chugai Pharmaceutical Co Ltd
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of FR2605222A1 publication Critical patent/FR2605222A1/fr
Application granted granted Critical
Publication of FR2605222B1 publication Critical patent/FR2605222B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
FR878711957A 1986-08-27 1987-08-26 Agent therapeutique a base de nitrate de n-(2-hydroxyethyl) nicotinamide pour le traitement de troubles associes a l'ischemie cerebrale Expired - Fee Related FR2605222B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP19879686 1986-08-27

Publications (2)

Publication Number Publication Date
FR2605222A1 FR2605222A1 (fr) 1988-04-22
FR2605222B1 true FR2605222B1 (fr) 1991-02-22

Family

ID=16397046

Family Applications (1)

Application Number Title Priority Date Filing Date
FR878711957A Expired - Fee Related FR2605222B1 (fr) 1986-08-27 1987-08-26 Agent therapeutique a base de nitrate de n-(2-hydroxyethyl) nicotinamide pour le traitement de troubles associes a l'ischemie cerebrale

Country Status (22)

Country Link
US (1) US4870090A (fr)
JP (1) JPH07121863B2 (fr)
KR (1) KR950002151B1 (fr)
AU (1) AU603375B2 (fr)
BE (1) BE1003959A5 (fr)
CA (1) CA1302888C (fr)
CH (1) CH672069A5 (fr)
DE (1) DE3728499A1 (fr)
DK (1) DK171392B1 (fr)
FI (1) FI873727A (fr)
FR (1) FR2605222B1 (fr)
GB (1) GB2195532B (fr)
HK (1) HK64993A (fr)
IE (1) IE60601B1 (fr)
IT (1) IT1211477B (fr)
LU (1) LU86973A1 (fr)
NL (1) NL8701994A (fr)
NO (1) NO873571L (fr)
NZ (1) NZ221564A (fr)
SE (1) SE502323C2 (fr)
SG (1) SG52393G (fr)
ZA (1) ZA876401B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5736529A (en) * 1996-03-22 1998-04-07 Neurocal International Inc. Use of NAD-related compounds in the treatment of neural trauma to inhibit neurodegeneration
WO1999020284A1 (fr) * 1997-10-23 1999-04-29 Trustees Of The University Of Pennsylvania Procedes utiles pour reduire des lesions ischemiques du coeur par l'administration sequentielle d'agents de lipide a monophosphoryle et de recepteurs d'adenosine
AU4841700A (en) 1999-05-12 2000-11-21 Nitromed, Inc. Nitrosated and nitrosylated potassium channel activators, compositions and methods of use
CN107773545A (zh) * 2016-08-29 2018-03-09 烟台益诺依生物医药科技有限公司 依达拉奉与(+)‑2‑莰醇的舌下用药物组合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200640A (en) * 1976-04-02 1980-04-29 Chugai Seiyaku Kabushiki Kaisha Nitric ester of N-(2-hydroxyethyl)nicotinamide and pharmaceutical use
GB1562962A (en) * 1976-04-02 1980-03-19 Chugai Pharmaceutical Co Ltd Nicotinamide derivatives processes for producting the same and pharmaceutical compositions containing the same
EP0223811A1 (fr) * 1985-05-22 1987-06-03 Beecham Group Plc Utilisation de nicorandile ou de pinacidile dans le traitement de maladies vasculaires peripheriques
US4696934A (en) * 1986-01-10 1987-09-29 Warner-Lambert Company Method for using nifedipine for treating stroke
EP0259309A1 (fr) * 1986-03-14 1988-03-16 Medical College Of Wisconsin Research Foundation, Inc. Procede de traitement et de prevention de spasmes vasculaires cerebraux

Also Published As

Publication number Publication date
US4870090A (en) 1989-09-26
IT8767725A0 (it) 1987-08-21
JPH07121863B2 (ja) 1995-12-25
BE1003959A5 (fr) 1992-07-22
SG52393G (en) 1993-08-06
ZA876401B (en) 1988-04-27
CA1302888C (fr) 1992-06-09
FI873727A0 (fi) 1987-08-27
SE8703308L (sv) 1988-02-28
JPS63152317A (ja) 1988-06-24
GB8720219D0 (en) 1987-10-07
LU86973A1 (fr) 1987-12-16
NO873571L (no) 1988-02-29
GB2195532B (en) 1990-05-23
NZ221564A (en) 1999-08-30
AU603375B2 (en) 1990-11-15
SE8703308D0 (sv) 1987-08-26
SE502323C2 (sv) 1995-10-02
NL8701994A (nl) 1988-03-16
DK441987A (da) 1988-02-28
FI873727A (fi) 1988-02-28
NO873571D0 (no) 1987-08-24
KR880002525A (ko) 1988-05-09
KR950002151B1 (ko) 1995-03-14
AU7731187A (en) 1988-03-03
DK171392B1 (da) 1996-10-14
DE3728499A1 (de) 1988-03-03
HK64993A (en) 1993-07-16
DK441987D0 (da) 1987-08-25
CH672069A5 (fr) 1989-10-31
IE872218L (en) 1988-02-27
IT1211477B (it) 1989-11-03
FR2605222A1 (fr) 1988-04-22
GB2195532A (en) 1988-04-13
IE60601B1 (en) 1994-07-27

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Legal Events

Date Code Title Description
ST Notification of lapse